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Normal Arterial Serum pH 7.35-7.

45
Oxygen (PaO2) 80-100 mm Hg
Blood Gases Carbon dioxide (PaCO2) 35-45mm Hg
Bicarbonate (HCO3-) 22-26 mEq/L
Base Excess +3 to -3
Normal Serum Sodium 135-145 mEq/L
Potassium 3.5-5.1 mEq/L
Electrolytes Chloride 98-107 mEq/L
Bicarbonate (venous) 23-29 mEq/L
Calcium 9-10.5mg/dL total or
4.6-5.1mg/dL ionized
Magnesium 1.8-3 mg/dL
Phosphorous 3-4.5mg/dL
Normal Adult Fasting blood glucose 70-110mg/dL
Random (capillary) glucose 60-110 mg/dL
Glucose Levels 2-hour postprandial blood <140 mg/dL
glucose
Oral glucose tolerance test (OGTT)
Fasting baseline 70-110 mg/dL
30-minute sample 110-170 mg/dL
60-minute sample 120-170 mg/dL
90-minute sample 100-140 mg/dL
120-minute sample 70-120 mg/dL
Glycosylated hemoglobin A1c
Normal 3.5-6%
Good Diabetic Control 7.5% or lower
Fair Diabetic Control 7.6%-8.9%
Poor Diabetic Control 9% or higher
Coagulation Prothrombin Time (PT) 9.6-11.8 seconds for adult
males and 9.5-11.3 seconds
Studies for adult females.
Therapeutic level for
warfarin is 1.5 to 2 times the
control.
International Normalized Ratio 2.0-3.0 for normal warfarin
(INR) therapy
3.0-4.5 for high dose therapy
Activated Partial Thromboplastin 20-35 seconds, therapeutic
time (aPTT) range for heparin therapy is
1.5-2.5 times the controls.
Clotting time (measures time of 8-15 minutes
clotting process)
Complete Blood Hematocrit (Hct) [proportion of Males: 40-50%
RBCs in a volume of whole Females 38-47%
Count blood]
Hemoglobin Males: 13.5-18 grams/dL
Females: 12-16 grams/ dL
RBC count Males: 4.5-6.2 million cells/
microliter
Females: 4.0-5.5 million
cells/ microliter
Platelet count 150, 000-450, 000 per cubic
mm (mm3)
WBC (consists Total WBC 5000-10,000 cells/mm3
of Monocytes Neutrophils 50-70% or 2500-7000
and (total) cells/microliter
lymphocytes; Segments 50-65% or 2500-6500
no stainable (mature) cells/microliter
granules in Bands 0-5% or 0-500
nucleus) and (immature) cells/microliter
granulocytes [increase
(neutrophils, indicate
eosinophils, and inflammation
basophils) or infection,
demand
outweigh
production]
Eosinophils 1-3% or 100-300
[increase cells/microliter
indicate
allergic and
parasitic
conditions and
decrease with
higher level of
steroids]
Basophils 0.4-1.0% or 40-100
(increase cells/microliter
during healing
process and
decrease when
steroid levels
rise)
Lymphocytes 25-35% or 1700-3500
(increase cells/microliter
during chronic
and viral
infections and
lymphocytic
leukemia)
Monocytes 4-6% or 200-600 cells/
(phagocytes, microliter
ingest debris)
Cardiovascular Serum Lipids Total < 200 mg/dL
(elevated levels Cholesterol
Function Studies of total
cholesterol, low
density
lipoproteins LDL < 130 mg/dL
(LDLs) and
triglycerides
increase risk of
heart disease,
stroke, HDL 30-70 mg/dL
peripheral
vascular
disease. While
High density
lipoproteins Triglycerides < 200 mg/dL, increased
have a levels indicate
cardioprotective hyperlipidemia (possibly
function) familial)

Cardiac Creatine Males: 55-170 units/L


Enzymes Kinase (CK) Females: 30-135 units/L

CK-MM(skel.) 94-100%
CK-MB(cardi) 0-6%
CK-BB(brain) 0%
(begins to rise
4-6 hrs after
myocardial or
skeletal
muscle
damage, peaks
at 18-24hrs
and returns to
normal within
3-4 days)
Lactic 140-280 units/L
dehydrogenase
(LDH)
LDH1 14-26%
LDH2 29-39%
LDH3 20-26%
LDH4 8-16%
LDH5 6-16%
(begins to rise
24 hours after
myocardial
damage, peaks
in 48-72hours
and returns to
normal within
7-14 days)
Cardiac
Troponins

Troponin I <0.1 to <1.0ng/mL


Troponin T <0.2 to <1.0ng/mL
(rise within 3
hours of
myocardial
infarction,
returns to
normal in 5-9
days (I) or 10-
14 days (T)
Thyroid Function Thyroxine (T4) (major hormone 4.5-11.5 mcg/mL or 1.0-2.3
secreted by thyroid gland, low ng/dL free T4
Studies levels=hypothyroidism and high
levels= hyperthyroidism)

Triiodothyronine (T3) (a short 80-200 ng/dL


acting but potent thyroid
hormone, more useful in
diagnosing hyperthyroidism than
hypothyroidism)
Thyroid Stimulating hormone 0.5-4 microinternational
(TSH) (a hormone secreted via units/mL
negative feedback loop by
anterior pituitary in response to
decreased T4, used with T4 level
to differentiate between pituitary
and thyroid dysfunction)
[decreased T4 and normal or
elevated TSH is consistent with
thyroid disorder]
[decreased T4 and decreased
TSH is consistent with pituitary
disorder]
Renal Function Blood urea nitrogen (BUN) 8-22 mg/dL
(formed in liver as end product [rises with reduced GFR,
Studies of protein metabolism; consists increased dietary protein,
of nitrogen portion of urea; increased catabolism (such
excreted via kidneys with only as starvation), crush injuries,
small amounts reabsorbed in febrile illness, absorption of
renal tubules) blood from intestines, and
with hemoconcentration
from dehydration]
[decreases with
overhydration, inadequate
protein intake, or liver
disease (liver is not
adequately converting
ammonia to urea) ]
Serum Creatinine (end product of 0.6-1.3 mg/dL
muscle Creatinine metabolism; [elevated levels indicate
specific indicator of GFR and renal insufficiency or failure]
renal status)

Creatinine Clearance Males: 95-135mL/min


(compares serum Creatinine with Females: 85-125 mL/min
excreted Creatinine in a volume
of urine over a period of hours)

Serum Osmolality 280-296 mOsm/kg water


[reflects concentration of serum
(number of osmotically active
particles in solution)] often used
to detect risk of increased
Intracranial pressure]
Urine Osmolality 500-800 mOsm/kg water
(measures concentration of urine, (average)
as does specific gravity) 50-1,400 mOsm/kg water
[high values indicate kidneys are (extremes)
conserving water, while low
values may reflect increased
fluid intake, effect of diuretics,
diabetes insipidus, or renal
damage; clinical correlation is
needed]
Urinalysis Nitrites (if present suggest Dietary nitrates are excreted
urinary tract infection) in urine, when Gram-
negative bacteria (such as
common E. coli) are present
in urine these nitrates are
converted to nitrites, test
suggests UTI with gram-
negative bacteria, false-
negatives can result if urine
does not sit in bladder long
enough (greater or equal to
4hrs), for reaction to take
place, if infection is not
caused by gram-negative
organism, or if dietary nitrate
is absent.
Leukocyte esterase Simple test that may be
done on voided urine
sample; positive result
suggests UTI. White blood
cells contain esterases that
react with substances in
urine. More than 100, 000
colonies of bacteria (per
high-powered field) needed
for UTI diagnosis.
Normal Color Ranges from pale yellow to
Urinalysis amber
Findings

Clarity Clear when first excreted

Odor Faintly aromatic

Specific 1.005-1030
gravity

pH 4.6-6.0
Protein Trace to none

Glucose None

Ketones None

Sediment 0-3 RBCs, 0-4 WBCs;


occasional cast; occasional
renal epithelial cell

Abnormal Color Pale: Diabetes insipidus,


Urinalysis drinking of excess free
Findings water.
Reddish: RBCs
Burgundy: porphyria (refers
to a group of disorders that
result from a buildup of
natural chemicals that
produce porphyrin in your
body. Porphyrins are
essential for the function of
hemoglobin — a protein in
your red blood cells that
links to porphyrin, binds
iron, and carries oxygen to
your organs and tissue).
Orange: phenazopyridine
HCL (Pyridium) or rifampin
(Rifadin).
Green: bile
Black-brown: mercury
poisoning
Milky: pus, fat globules
Clarity Cloudy: infection, phosphate
precipitation from standing.
Turbid(thick): spermatozoa,
prostatic fluid

Odor Sweet: Acetonuria


Strong: drugs, asparagus
Ammonia: after standing for
a time.

Specific Decreased: diabetes


gravity insipidus, diuretics,
excessive intake of free
water.
Increased: diabetes mellitus,
hypovolemia, liver disease,
heart disease, SIADH, IV
contrast medium
pH Acid: acidosis, diabetes
mellitus, fever, starvation,
dehydration.
Alkaline: citrus, salicylate
poisoning, sodium
bicarbonate, urinary tract
infection; urine becomes
alkaline after standing
because urea-splitting
bacteria result in ammonia
production.
Protein Transient: fever, stress

0.5 gram/day: pyelonephritis

0.5- 4 grams/day: multiple


myeloma, diabetic
nephropathy.

5 grams/day: nephrotic
syndrome,
glomerulonephritis.

Glucose Present: Diabetes Mellitus


Ketones Present: acidosis, diabetic
ketoacidosis, starvation, or
dieting (fat breakdown).

Sediments Casts: clumps or material or


cells that form in renal
collecting tubule, assuming
shape of tubule; are seen in
various renal disease states.
Granular casts: acute tubular
necrosis, glomerulonephritis,
UTI, stress, renal transplant
rejection.
Pus: glomerulonephritis
RBC casts:
glomerulonephritis
WBCs: UTI
RBCs: bleeding with
glomeruli, transfusion
reaction, malaria, hemolytic
anemia.
Liver Function Alanine aminotransferase (ALT) 10-25 units/L
[found primarily in liver cells but [rise as high as 200-400 units
Studies also found in small amounts in with hepatitis or liver
heart, kidney, and skeletal damage from drugs and
muscle] chemicals]
[used to differentiate
between jaundice caused by
liver disease (often >300
units/L) and causes outside
liver (often < 300 units/L).]
Aspartate aminotransferase 8-38 units/L
(AST) [enzyme found mainly in [rises with cellular injury
the heart muscle and liver, with and release of enzyme into
moderate amounts found also in circulation]
skeletal muscle, kidneys and [rises following MI in 6-10
pancreas] hours, peaks in 24-48 hours,
and returns to normal in 4-6
days; rarely used because not
specific to myocardial tissue]
[with liver injury (hepatitis,
necrosis), levels rise by 10
times or more and stay
elevated longer; also rises
with pancreatitis and
musculoskeletal trauma,
including injections.

Bilirubin Total: 0.1-1.2 mg/dL adults


and 1-12mg/dL newborn.
Direct 0.1-0.3 mg/dL
Indirect: calculate by
subtracting direct from total.
Ammonia 35-65 micrograms/dL

Pancreatic Amylase 25-151 units/L


(produced by pancreas and [increased with pancreatitis;
Enzymes salivary glands for carb. elevation begins 3 to 6 hrs
digestion and excreted by after pain begins, peaks in 24
kidneys.) hours and returns to normal
in 2 to 3 days]
[false results can occur if
measured within 72 hours of
cholecystography with
radiopaque dyes]
Lipase 10-140 units/L
(produced by pancreas to break [increased with pancreatic
down fats and triglycerides into disorders; may rise as late as
fatty acids and glycerol) 24 to 36 hours after onset of
disorder and return to normal
as much as 14 days later.]
Metabolic Prealbumin 12-50 mg/dL
[Is also known as thyroxin- [low values indicate need for
Function Studies binding prealbumin or comprehensive nutritional
transthyretin, it is a sensitive evaluation (history, weight,
indicator of recent changes in anthropometric
catabolism because half-life is measurements, calorie count]
less than 2 days] [High values are found in
[used to screen for nutritional renal failure because of poor
problems and gauge renal excretion]
effectiveness of nutrition
therapy]
Albumin 3.4-5.0 grams/dL
[A plasma protein that maintains [may be decreased with
oncotic pressure (to prevent malnourished states and
edema) and transports water monitored as an indicator of
soluble substances (fatty acids, nutritional status]
hormones, bilirubin, drugs]
Total protein 6.0-8.0 grams/dL
[consists of circulating albumin [may be decreased with
and globulins in serum; serve malnutrition, low protein
many functions, including tissue diet, GI disorders, severe
growth and repair, pH buffering, liver disease, chronic renal
enzymes, hormones, and failure, severe burns, or
coagulation factors] water intoxication]
[may be increased with
dehydration
(hemoconcentration),
vomiting, diarrhea, and
myeloma]
Alkaline Phosphatase 4.5-1.3 King-Armstrong
(enzyme present in intestines, units/dL
liver, bone and placenta) [rises with periods of growth
and liver disease or bile duct
obstruction]
[results may be affected by
hepatotoxic drugs given 12
hrs before test]
Uric acid Males (adult): 3.5-8.0 mg/dL
(by-product of purine Females:2.8-6.8 mg/dL
metabolism; is elevated in gout; [excessive uric acid can lead
is affected by diet and renal to kidney stone formation as
function) renal clearance occurs]
[teach client to avoid high
purine foods such as liver,
kidney, brain, heart,
sweetbreads, scallops and
sardines prior to test]

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