DAFTAR ISI

HALAMAN JUDUL .................................................................................................. i

LEMBAR PENGESAHAN ....................................................................................... ii
PERNYATAAN KEASLIAN TULISAN ................................................................ iii
KATA PENGANTAR ............................................................................................... iv
DAFTAR ISI .............................................................................................................. v
DAFTAR TABEL ...................................................................................................... vi
DAFTAR GAMBAR ................................................................................................. vii
DAFTAR SINGKATAN ........................................................................................... viii
BAB I PENDAHULUAN .......................................................................................... 1
BAB II TINJAUAN PUSTAKA ............................................................................... 2
2.1 Chronic Kidney Disease ........................................................................................ 2
2.1.1 Definisi ......................................................................................................... 2
2.1.2 Etiologi ......................................................................................................... 2
2.1.3 Klasifikasi Stadium ...................................................................................... 2
2.1.4 Patofisiologi ................................................................................................. 4
2.1.5 Gambaran Klinis .......................................................................................... 5
2.1.6 Penegakan Diagnosis ................................................................................... 6
2.1.7 Penatalaksanaan ........................................................................................... 7
2.2 Diabetes Mellitus .................................................................................................. 8
2.2.1 Definisi ......................................................................................................... 8
2.2.2 Epidemiologi ................................................................................................ 8
2.2.3 Klasifikasi ..................................................................................................... 9
2.2.4 Manifestasi Klinis ......................................................................................... 9
2.2.5 Diagnosis ...................................................................................................... 10
2.2.6 Penatalaksanaan ............................................................................................ 13
BAB III LANDASAN TEORI .................................................................................. 14
3.1 Landasan Teori .............................................................................................. 14
3.2 Kerangka Konsep ......................................................................................... 15
BAB IV METODE PENELITIAN ........................................................................... 16
4.1 Jenis dan Rancangan penelitian ................................................................... 16
4.2 Populasi Penelitian ...................................................................................... 16
4.3 Sampel dan Teknik Pengambilan Sampel ................................................... 16

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 4.4 Estimasi Besar Sampel ................................................................................. 16
4.5 Kriteria Pemilihan ........................................................................................ 17
4.5.1 Kriteria Inkulsi ..................................................................................... 17
4.5.2 Kriteria Eksklusi ................................................................................... 17
4.6 Variabel Penelitian ....................................................................................... 17
4.6.1 Variabel Bebas ...................................................................................... 17
4.6.2 Variabel Tergantung ............................................................................. 17
4.7 Definisi Operasional ..................................................................................... 18
4.8 Instrumental Penelitian ................................................................................. 18
4.9 Prosedur Pengumpulan Data ......................................................................... 18
4.10 Cara Pengolahan Data dan Teknik Analisis Data ....................................... 19
4.10.1 Pengolahan Data .................................................................................. 19
4.10.2 Analisis Data ........................................................................................ 19
4.11 Alur Penelitian ............................................................................................. 20
BAB V HASIL DAN PEMBAHASAN ...................................................................... 21
5.1 Hasil ............................................................................................................... 21
5.2 Pembahasan ...................................................................................................
DAFTAR PUSTAKA....................................................................................................

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 DAFTAR GAMBAR

Gambar 2.1 Piramid iskemik dan sklerosis arteri dan arteriol pada potongan lintang
ginjal ..................................................................................................... 4
Gambar 3.1 Kerangka Konsep Penelitian ................................................................. 15
Gambar 4.1 Alur Penelitian ....................................................................................... 20

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 DAFTAR TABEL

Tabel 2.1 Stadium Chronic Kidney Disease ...................................................................... 3

Tabel 2.2 Rencana Tatalaksana CKD Sesuai Stadium ....................................................... 7
Tabel 2.3 Perbandingan antara DM tipe 1 dan DM tipe 2 .................................................. 10
Tabel 2.4 Kriteria Diagnosis Diabetes Melitus ................................................................... 11

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 DAFTAR SINGKATAN

ADA : American Diabetes Association

BUN : Blood Urea Nitrogen
CKD : Chronic Kidney Disease
CT : Computed Tomography
DM : Diabetes Mellitus
EIA : Immunoassay
GDPT : Glukosa Darah Puasa Terganggu
GFR : Glomerulus Filtration Rate
HPLC : High Performance Liquid Chromatography
IGF-1 : Insuline-like Growth Factor 1
MRI : Magnetic Resonance Imaging
OHO : Obat Hipoglikemik Oral
TTGO : Tes Toleransi Glukosa Oral
TGT : Toleransi Glukosa Terganggu
WHO : World Health Organization