RSC - IW - SRSM-2019 - Souvenir & Abstracts Book Final2 PDF

Organised by In Associaton with
Department of Chemistry Royal Society of Chemistry &

Uka Tarsadia University The National Academy of
Bardoli, Gujarat – 394 350 Sciences India
Sponsored by
Department of Science & Technology

Government of Gujarat
BPKM
Promoting Society Through
Quality Education Since 2011…
120 Acre
Green
Campus
50+
Collaborations/ 21 Institutes
MoUs
10000+ 550+
Students Faculties
Table of Content
SN Details Page No
1. About Uka Tarsadia University 01
2. About RSC & NASI 03
3. About GSBTM and GOJCOST 04
4. Goodwill Messages 05
5. About Department of Chemistry, UTU 13
6. RSC-IW-SRSM-2019 Committee 31
7. Program Out Line 32
8. Invited Lectures 33
9. Oral Presentations 39
10. Poster Presentations 68

01
About Uka Tarsadia University
Uka Tarsadia University, popularly known as UTU has been established in 2011
by Bardoli Pradesh Kelavani Mandal, with an objective of meeting the growing
demand for quality education. The University offers a comprehensive array of
academic programs across the disciplines of Applied Science viz. Chemistry,
Physics, Mathematics, Biotechnology, Microbiology etc., Management,
Commerce, Engineering and Technology, Architecture, Design, Computer
Science, Pharmacy, Nursing, Physiotherapy and others that lead students to
self-enrichment and productive careers in their respective professions,
government, business and industry. The University being located near the
town of Bardoli, Gujarat on a 120 acre land assures educational opportunities
to over 10,000 students. UTU has epitomized excellence in imparting the
research oriented education in the state of Gujarat, having well experienced
dynamic faculty members and equipped with adequate and state-of-art
infrastructure linked with internet (Wi-Fi) facilities.
MISSION
To serve the society by creation, augmentation, dissemination and
perpetuation of knowledge through highest level of learning and research.
VISION
To become a preeminent education hub that is responsive to the changing
needs of a knowledge-based global society.
OBJECTIVES
 To impart holistic education in the context of dynamic global challenges.
 To mobilize resources which promote acquisition, retention and application
of knowledge.
 To provide a platform for economic development through collaboration
with academic institutes and industries.
02
About Uka Tarsadia University

03
About Royal Society of Chemistry

The Royal Society of Chemistry (RSC) is a learned society of United Kingdom with the goal
of “advancing the chemical sciences.” The headquarters of the Society is at Burlington
House, Piccadilly, London (U.K.) along with branch offices in the United States at the
University City Science Centre, Philadelphia, in Beijing and Shanghai, China and in
Bangalore, India.
The RSC-IW section organizes a wide range of events to support chemical scientists at all
stages in their careers including frequent lectures and symposia, popular science events
and activities for postgraduates and undergraduates.
RSC-IW Symposium & Research Scholars Meet-2019 is an event organized for research
scholars and young academicians to showcase their research in front of distinguished
panellists from RSC-IW section. This is an unique opportunity especially for young doctoral
research scholars to interact with eminent scientists and fellow scholars from different
institutions of Western India region. The scientific sessions are consisting of 6 to 7 expert
lectures by eminent academicians/ researchers, and other short lectures by students, and
poster presentations.
About The National Academy of Sciences India

The National Academy of Sciences, India (NASI), established in 1930, is the oldest science
academy in India. It is headquartered in Prayagraj. The objectives of the NASI are cultivation
and promotion of Science and Technology in all its branches, providing a national forum for
publication of research work, holding symposia/seminars on scientific topics of national
relevance, organizing a Science Library including students section, organizing meetings and
discussions on scientific and technological problems, concerned with the problems of
national welfare, creating an adequate impact of the Academy all over the country, by
opening Chapters of the Academy in other cities in the country, where reasonable number
of Fellows and Members are available. Currently NASI has twenty local Chapters, of which
one is located in Mumbai. The research journal, Proceedings of the Academy, being
published regularly in two sections covering Physical Sciences and Biological Sciences. The
Academy also publishes a monthly research journal, ‘National Academy Science Letters.
04
About GSBTM
The State Government of Gujarat, in its resolve and continued endeavors for socio-economic up-liftment of
society, has identified Biotechnology as most potential tool for development. The State intends to promote
biotechnology sector by building appropriate image, encouraging entrepreneurship, strengthening
organizational colorations and forecasting business partnerships. For facilitating the development of
biotechnology in the State, Government of Gujarat has constituted Gujarat State Biotechnology Mission,
under the aegis of Department of Science and Technology.
Vision
To realize and harness the potential of Biotechnology as a human endeavor for the highest intellectual pursuit
and as an effective future delivery system for creating a disease free, nutritionally secure society living in safe,
clean environment, leading to overall socio-economic growth, welfare and progress of humanity.
Mission
GSBTM will promote, support and facilitate the development of biotechnology in the state by promoting
research and development in the field of biotechnology, by generating the quality human resource in the field
of biotechnology and by supporting the development of biotechnology industries by taking effective
measures and policy and planning level. To promote, support and facilitate the overall development of
Biotechnology in the State To provide institutional, legal, financial and policy support To facilitate networking
among stakeholders at Regional, National and International level To facilitate the infrastructure development
and R&D activities To create scientific awareness, sensitization, socio-ethical acceptance and adoption to the
potentials and application of biotechnology.
About GUJCOST
The Gujarat Council on Science and Technology (GUJCOST) was established in September, 1986, to play a
catalytic role in promoting the use of Science and Technology in the development process of the State. The
S&T Council was constituted with a view to develop technologies appropriate to and in harmony with present
conditions. The Council has been catalyzing interaction between developers and users of technologies, by
bringing on a common platform to training Scientists and Engineers on the one hand and policy makers as
well as administrators on the other.
Vision
"Gujarat Council on Science and Technology shall act as a focal forum to inculcate scientific temper for
attaining new heights in research and development for welfare of masses and to improve the quality of their
life as well as to solve important issues of socio-economic development of the state by acting as organic link
between science, technology and economy.”
Mission
"GUJCOST will dedicated to educating young minds, assisting teachers and increasing public understanding of
science and technology along with its research and development programmes.”
05
Messages
06
Messages
07
Messages
08
Messages
Prof. D. R. Shah
Provost,
Uka Tarsadia University,
Bardoli
It gives me immense pleasure to hear that the Department of Chemistry in

association with Royal Society of Chemistry India West and The National Academy of
Sciences have been organizing “RSC India West Chapter Symposium and Research
Scholar Meet – 2019” during 22nd – 23rd February 2019.
The Department of Chemistry right from its inception has been devoted towards the
creation of an up-to-date academic environment for its students and research
scholar. This research scholar meet – 2019 will bring together people of varied
experiences and provide an opportunity for all the participant to share their
thoughts and contribution to science. Mutual participation and high quality
deliberations in this meet would create inspiring learning environment resulting into
innovative ideas for all of us.
Advances in Chemical Sciences offer solution for numerous problems of society and
thereby promote human wellbeing. It is expected that this endeavour of the
organizers will create a ways to link the people from different area of research. Also
Uka Tarsadia University has always strived hard to inculcate a culture of innovation
and creativity in our students and faculty members. Also the university has been in
the forefront in organising national as well as international conferences, seminars
and workshops on the subject relevant to different areas of education. This research
scholar meet is another step in our endeavour to provide a platform to the scholars,
academics and industries to deliberate upon and map the chemical sciences in new
era.
I express my gratitude towards all the dignitaries and academic luminaries for their
active participation in this meet. I also congratulate the Ex-Director Prof. K R Desai,
I/C Director Ajit Joshi, scientific committee, coordinators, students, reviewers and
faculty for their contribution to this meet. I also congratulate all the young scientists
who had participated in this meet and wish them all the best for their future
research endeavours. The proceedings of this meet will be of great source of
information to the scholars, academicians and industrialists.
I wish the meet all success and a pleasent stay of the delegates coming from
different parts of the India.
Prof. D. R. Shah
Provost,
Uka Tarsadia University,
Bardoli
09
Messages
It is a matter of great honour and privilege for us to be associated with the program
that has been organized by Uka Tarsadia University. This is the first time that I have
been to a University in a rural environment.
I am pleased to extend my hearty welcome to all participants of “Royal Society of

Chemistry India West (RSC-IW) Symposium and Research Scholar Meet-2019”.
Conferences and Symposiums are great opportunities not only for researchers and
scientists, but also for experts, policy makers, stakeholders and students. Organizing
such events on academic campus allows us to learn new information and tactics
from hearing others’ presentations, you also can converse with other researchers
from different universities and even countries you may have only heard or read
about.
I am happy to express that the symposium is going to held under the joint-support of
the Royal Society of Chemistry and NASI. The enthusiasm shown by the Faculty and
the students of your University is heart warming. This is reflected in the large
number of posters. I sincerely hope that we will be able to come to your
expectations. I congratulate Uka Tarsadia University for organizing and hosting such
mega event to provide very unique platform to young researcher of our state.
Both the Royal Society of Chemistry (West India Chapter) and the National
Prof. Girjesh Govil

President, RSC (UK), Western Zone India,
NASI, Senior Scientist
TIFR, Mumbai
10
Messages
11
Messages
12
Messages
It’s appreciable and delighted news, as the Chemistry Department of Uka Tarsadia
University is organizing Royal Society of Chemistry India West Chapter Symposium and
Research Scholars Meet -2019 (RSC-IW-SRSM-2019) in association with Royal Society of
Chemistry India West and The National Academy of Sciences, India (Mumbai Chapter).
Academic conferences provide opportunities to students to build networks with other
academics and experts in the similar field of studies all around the world and to share
thoughts on recent advances and technological breakthroughs. These also provide
feasibility to meet new people with different cultures and dispositions enlighten the way
of thinking in your field of study. It is an imperative chance to find out what’s new in your
field of study to survive in an academic discipline.
Chemistry is an ever growing specialized area in Applied Sciences, as it is a broad science

incorporates the concepts of creation of molecules and dealt with nano level to macro
level materials and their applications. Chemistry forms the indispensable foundation of
disciplines such as biology, medicine, and materials sciences. Universities have a vital
role in the training of excellent people and as partners with industry in collaborative R&D
projects. These kind of conferences make a bridge of understanding between academic
institutes and various organizations and thus may enhance the relations related to
placements/ start-up programs.
I hope that all the delegates in this symposium will participate with full enthusiasm and
carry out fruitful and valuable interactions with various renowned professors. I also wish
the young generation for their success in basic R&D and entrepreneurships.
Dr. AJIT JOSHI

I/C Director & Associate Professor,
Department of Chemistry,
Uka Tarsadia University
Maliba Campus,
Bardoli-Mahuva Road,
Surat-394350 (Guj.)
Mobile: +91-9413805777
E-mail: ajit.joshi@utu.ac.in;
13
Department of Chemistry
It is our proud privilege to welcome you all at Department of Chemistry, UTU. Department
of Chemistry was started in 2011 and we came to exist on 12th April 2016 as separate
independent department of UTU. Presently Department of Chemistry is one of the leading
departments in the university which offers BSc (Hons.) Chemistry, Integrated MSc
Chemistry, post graduate MSc-Organic, Pharmaceutical, Industrial, Analytical Chemistry
courses. The department was started with 30 students and today we have well over 1000
students enrolled in BSc, MSc and Ph.D. degrees.
Over the years, department has progressed at rapid pace with development in both
spheres of infrastructure facilities and academic programmes. The department is also
having all facilities to pursue the PhD program. The faculties of department are having the
experience across the world and along with teaching based on their experience, they are
also actively engaged in various fields of research. In order to nurture the research
atmosphere, department is also having various types of collaborations and MoU signed
with various industries as well as academic institutes.
Be the 1 st in Chemistry through excellence in research & education to become Gujarat’s

What?
leading department for developing technological solutions to meet the state challenges
Why?
Meet the state aspirations and objectives

Research - Education
Alumni Engagement
Entrepreneurship &
Flexible Academic
Collaborations
Engagements
International
Programmes
Start-up Cell
High-Quality
& Outreach
Industrial
How?
Faculties and Staffs Students

Enablers
Infrastructure, Facilities and Freedom
Pursuing world- Creating value

Developing high class research Nurturing through
Activities
quality human including integrity, technology

Core
resources to serve translational and creativity and development that

the state transformational academic freedom addresses state
research challenges
14
Our Authenticity
Graduands’ Pledge
“We the graduates and post-graduates of the Department of Chemistry, UTU, hereby
pledge that we shall, in thought, word and deed ever endeavour to be scrupulously
honest in the discharge of our duties, that in all circumstances, we shall uphold the
dignity and integrity of our profession and the honour of our Institute and the nation
and that we shall devote all our energies to promote the unity and secular ideal of
our country and utilise our knowledge in the service of our nation and society”
© Department of Chemistry, UTU 2019

This publication is available in electronic form at:
http://www.utu.ac.in/dchemistry/index.html
Text and design: Department of Chemistry
15
Faculty Strength
“We are having versatile subject expert faculty members worked with various national and
international Institutes and Universities across the globe. Based on our exposer with those
Institutes and Universities, trying our best to strengthen our department to make it a role
model for other Institutes and University. We are very actively involved is various
academic as well as research activities for the betterment of students, university and
ultimately society.”
“We believe to work in a team because teamwork is the knack to work together for a
common vision. Our aptitude to direct individual accomplishments toward organizational
objectives. These two are the fuel that allows us to attain uncommon vision”
We are oblige to follow the quote given by Sir A. P. J. Abdul Kalam
“Teaching is a very noble profession that shapes the character, caliber, and future of an
individual. If the people remember me as a good teacher, that will be the biggest
honour for me”
16
Department of Chemistry Faculty Profile

Dr Joshi’s group addresses unsolved problems in Chemistry,
Synthesis, Environmental Science, Medicine Chemistry, Natural
Products and Materials Science using new computational tools,
new reactions, reagents, strategies and design. The lab
emphasizes the use of chemistry, design and synthesis to
address problems of significance in allied science. During his 15
Years Industry and R&D experiences, he has
discovered/synthesis various new molecules, Intermediates, API
Dr. Ajit Joshi and its Impurities from mg scale to commercials scale as well as
I/C Director technology transfer to R&D to Plants. Have extensive
(PhD from MLSU, experience of following single to multi steps reaction from
Udaipur) milligrams to grams then scale up. Still they are ready to accept
all kind open challenge to rectify them as a team works.
“Dr Parth has completed his doctoral study from VNSGU. As a

part of his contribution to research community, he has worked
on design and synthesis of various novel heterocyclic systems.
Currently his group is working on design and synthesis of novel
heterocyclic lignands and their metal complexes with
application in medicinal and material science. They are also
working on extraction and isolation of biologically active natural
products from various plant materials. They are also working on Dr. Parth J. Naik
development of photo luminescent material” Assistant Professor
(PhD from VNSGU, Surat)
“Dr Battula and his team is working on construction of

exigent chemical bonds through metal free/ matal catalyzed
reactions wherein performed between various distinguished
electrophilic variants with diverse range of rational
nucleophiles and thus to develop conceptual multi
component reactions which leads to produce biologically
important heterocycles, and discover the applications of
these exigent chemical bond formations and heterocycles in
Dr. Satyanarayan Battula the biology. Furthermore, find out the utility of established
Assistant Professor chemical methods in the total synthesis of natural products
(PhD from CSIR-IIIM, and their libraries. In addition, interested to focus on
Jammu) NET-JRF discover the routes to innate C-H activations and related
applications.”
17
“Dr Paresh and his group is a team of professional chemists

including graduate, undergraduate and high school students.
They have a broad range research interests with the
development of sustainable chemical methods while dealing
with experimental challenges. They are working at the
interface of chemistry – biology and have a special interest in
development of sustainable method for nano material
Dr. Paresh N. Patel synthesis and their application in organic synthesis. They are
Assistant Professor developing bio-catalytic process for asymmetric synthesis.
(PhD from SPU, Anand They are also working on design and synthesis of
Post Doc from IIT Madras) photoluminescent molecules for PDT and sensor application.
“Dr Roy’s current and future research interests include studies

on specific uses of membrane vesicles as vehicles for targeted
drug delivery, host-guest complexation and
fluorimetric and colorimetric sensing of ions using organic
ligands etc. Synthesis of several antibiotic drugs based Schiff
bases and preparation of antibiotic drugs containing metal-
nanoparticles is also under way including their antibacterial
studies. DFT calculations using Gaussian09, of nanoparticles, Dr. Sutapa Mondal Roy
drugs, drug-nanoparticle interactions, organic ligand- Assistant Professor
cation/anion interactions etc is also in progress. QSTR and QSAR (PhD from Jadavpur
based studies of several ACAT inhibitors are ongoing with future University, Kolkata)
goal to develop QSTR and QSAR based models for six different CSIR-NET
ACAT inhibitors.”
“Dr Patil’s team is working on Color Chemistry, Dye Sensitized
Solar Cells (DSSC’s), Functional Organic Materials, Colorimetric
and Fluorescent sensors, Bio-sensors, pH sensors, Optical
Whiteners, NIR-absorbing/emitting molecules, to design and
synthesize multi-specialty organic molecules and conjugated
macro-molecules or polymers for fluorescent sensors, research
and development in chemistry for sustainability. Further he has
also explored his research domain in the field of Green
Dr. Sharad Patil Chemistry and Computational Chemistry (Design and various
Assistant Professor optimization for prior knowledge such as energy (stability),
(PhD from ICT Mumbai) simulated absorption/emission, conformers, Thermodynamic
CSIR-NET, SET (MH), GATE parameters, packing, geometrical parameters etc.).”
18
“Dr Dharmesh did his PhD (2014) from the Academy of

Scientific and Innovative Research (AcSIR), New Delhi. The
research work was carried out at CSMCRI, Bhavnagar,
Gujarat. He has worked as a Postdoctoral Researcher at the
University of Witwatersrand, Johannesburg, South Africa
during June 2014 to May 2016. His research work is on
polysaccharide modification, functional materials from
Dr. Dharmesh R. Chejara biopolymers, smart gels for biomedical applications. Further
Assistant Professor he has also explored his research domain in the field of
(PhD from AcSIR, natural products chemistry and medicinal chemistry with
Post Doc from South Africa) special reference to design and develop advanced drug
delivery systems.”
“Dr Jyoti’s research area is intensely focused on find out the

stability parameters and their related issues of metal ligand
complexes particularly for In(III), Ga(III),Cu(II) and Tl(I)
complexes through electrochemical as well as polorographic
studies, and determine their applications in Biomimetic
complexes are getting importance in the field of biosensors and
various fields. In addition, synthesizing various ionic liquids and
environmentally benign Lewis/ Bronsted catalysts possibly in
Dr. Jyoti Singh
newer methods and discover their applications/ utility in
Assistant Professor
various organic chemical reactions in green approaches, as now
(PhD from Rajasthan
a day’s these procedures took high importance in various
University.)
challenging organic reactions. She is looking forward to work in
organic synthesis and electrochemistry. Looking out for a
challenging in both field.
Dr Chintan did his Ph.D. (2013) from the Sardar Patel

University, Anand. He have worked as a Postdoctoral
Researcher at the University of KwaZulu-Natal, Durban,
South Africa during Aguest 2014 to Auguest 2017. His
research is on the development of mixed ligand metal
complexes and drug-based metal complexes and their
Dr. Chintan R. Patel biological activity. He currently working on homogeneous
Assistant Professor catalysis using cavitand capped metalloporphyrin and
(PhD from SPU, Anand, fluorometric sensing of metal ions using organic ligands and
Post Doc from, South Africa) supra molecules.
19
Completed Doctoral degree in National Institute of Technology

Rourkela (NITR) in the field of display device mateials and
sensing. From the joing in the UTU, focusingon developmentof
the optoelectronic properties of conjugated molecular
(Organic/Inorganic) and polymeric systems is a fascinating issue
in the design of new materials for light-emitting devices
(OLEDs/LEDs) and displays that offer bright colorsas well a high
degree of resolution. Addition to the same in my optoelectronic Dr. B. Rajamouli
materials laboratory (OEML), focusing multi-disciplinary Assistant Professor
research work such as luminescent organic fluorophores (deep (PhD from NIT Rourkela)
blue emitting materials), lanthanide complexes for
photodynamic therapy (PDT), molecular sensor, functional
dyesand theoretical (computational) calculations (DFT, TD-DFT).
To support the research work recently received University
research promotion scheme (RPS) fund.
Dr Jirimali is Contributing in the field of Bio-Nano-

Electro-materials for the development of Biosensors,
Biofuel cell, Electro-chromatography, capacitive
deionization, and Electro-osmotic-pump. Utilization of
the environmental waste for the generation of value
added products like hydroxyapatite, silica, activated
carbonmedicinal extracts, and biopolymers. Nano-
Dr. Harishchandra Jirimali materials for surface modifications used in anticorrosive,
Assistant Professor antimicrobial and UV-protective smart coatings. Nano
(PhD from CSMCRI, andmicroencapsulations of pesticidesand drugs.
Post Doc from South Korea) Analytical method development and Industrial
instrumental analysis.
Dr. Amrutlal Prajapat completed B.Sc. Chemistry

(2006),M.Sc. Polymer Chemistry (2008)from NMU, Jalgaon
(MH) and Ph.D. Science (2017) from Institute of Chemical
Technology, Mumbai, India.Currently, Dr. Prajapat from 2018
associated with UTU, Bardoli, Surat as an Assistant
Professor in Chemistry Department. The main research
interests include Cavitation phenomena, Wastewater Dr. Amrutlal Prajapat
treatment, Polymer synthesis, Depolymerization and Assistant Professor (PhD
Derivatization of natural polymers. Dr. Prajapat has more from ICT Mumbai)
than 4 years of industrial experience on analytical
instrumentation like XRD, XRF, BET, ICP etc.
20
“She aspire to make our students not only a good chemist but
also good responsible citizen of country. Being a Gold
Medalist, she is trying her best to impart best part of her
theoretical & practical knowledge to our students. Her area of
interest is in the subject of Physical chemistry which is bridge
connecting chemistry, physics & mathematics.” Ms. Rutu Patel
Teaching Assistant
(MSc from MSU, Baroda,
Gold Medalist)
“Mr Bhavin is pursing his doctoral degree for this

universty. His research interest is synthetic organic
chemistry, where he is working on the synthesis of
molecule that exhibits pharmaceutical importance,
particularly in the synthesis of heterocycles. He is also
working on the development of new synthetic
methodology through green processes based on
Mr. Bhavin R. Patel principles of Green Chemistry. In the green methodology,
Teaching Assistant my main focus on grinding approach for the synthesis of
(PhD pursing from UTU, molecules, ultrasound and microwave assisted organic
Bardoli) synthesis.”
“Dr Anand’s major research interest is in the area of drug

delivery system and developing new technologies for
delivery of poorly-soluble drugs. From past few years, he
is focusing on nanotechnology, especially the
incorporation of drugs into newly synthesised
biodegradable polymer for better bioavailability. His,
another area of interest is in formulation methods and
technologies that are employed to transport
pharmaceutical compounds to various sites in the body. It Dr. Anand Patel
may include synthetic drug carrier systems capable of Assistant Professor
improving the bioavailability and tissue-specific targeting (PhD from UTU, Bardoli)
of an active pharmaceutical ingredient (API) to the site of
desired drug action, such as targeting of cancer cells.”
21
“Dr Pramod has completed his doctoral study from

VNSGU. He has worked on the synthesis of various
thermally stable polymers. His research interest is in the
field of design and synthesis of advanced polymeric
material and their allpication in material science. He is
also working on design and synthesis of small organic
molecules with application in medicinal chemistry.” Dr. Pramod J. Patil
Assistant Professor
(PhD from VNSGU,
Surat)
“Dr Nilesh Pandya has done his doctoral study from

VNSGU. He has worked on synthesis of natural product
driven heterocyclic system. Currently he is working on
design and development of green and sustainable
methodology for various organic synthesis. He is also
Dr. Nilesh S. Pandya working on the application of carbohydrates in material
Assistant Professor sciences”.
(PhD from VNSGU,
Surat)
Mr. Dipen Desai

Teaching Assistant
(PhD Perusing from
UTU, Bardoli)
22
“Working in the field of Dyes Chemistry and also in

the field of new modified Drug synthesis that deals
with new concept of alternative and synthetic
strategies to synthesis heterocyclic , carbocyclic and
metal organic compounds.”
Nisha Odedara
Teaching Assistant
(MSc from VNSGU, Surat)
“Ms. Meghana has done her master with Physical

Chemistry from Veer Narmad South Gujarat
University. Her current and future research
interests are in the field of nanoscience, polymers,
material science, and colloidal chemistry. She is
Ms. Meghana V. Panchal currently working on “Synthesis of Nano-
Teaching Assistant Hyroxyapatite from Waste Egg Shells for the
Controlled Release of Urea”.
(MSc from VNSGU, Surat)
Ms. Shivani N. Tandel

Teaching Assistant
(MSc from UTU, Bardoli)
23
Department of Chemistry at Glimpse

Recognition of faculty members as well as students by scientific society
Dr. Sharad R. Patil, was honored to receive the

BHARAT VIKAS AWARD - 2018 by Institute of Self
Reliance (ISR), Bhubaneswar, for his loyalty,
diligence and outstanding performance in the
field of Color Chemistry and Effluent Water
Treatment
Senior Scientist Award had been awarded to

Mr. Bhavin R. Patel in International
Conference on “Chemical Sciences in New
Era” organized by Pacific Academy of Higher
Education and Research University in
association with Indian Chemical Society,
Kolkata during October 5-6,2018.
Dr. Rajamouli recived best poster presentation

award at GUJCOST Sponsored Two days
Seminar on “Targeted Bioconjugates for drug
delivery to cancer cells” organized by Maliba
Pharmacy College, Uka Tarsadia University,
UTU- Bordoli, on 5-6 October 2018.
Mr. Divyang Panchal and Ms. Preeti

Bhalodiya awarded 1st prize in poster
presentation during the National
Conference on “Global Opportunities in
Chemical, Biological & Material Sciences”
held on 28th & 29th December 2018.
24

Recognition of faculty members as well as students by scientific society
Ms. Preeti Bhalodiya, Ms. Nidhi Bhimani

and Ms. Shreya Patel have awarded 3rd
prize in poster presentation at National
Conference on “Global Opportunities in
Chemical, Biological & Material Sciences”
held on 28th & 29th December 2018.
Mr Chirag N Gadhiya Secured 58th Rank in CSIR-UGC-JRF, June – 2018.
Mousam, Saranya, Deepika, Vihang and Harshil got summer and winter internship with
fellowship at IIT Gandhinagar and IIT Goa.
25

Invited talk by faculty members
In order to develop the connection among the scientific community and to have
collaboration with other institutes, faculties are actively involved to deliver the invited
talk as various national as well as international conferences as well as workshop and
seminars.
Dr. Rajamouli Boddula delivered a invited talk at

6th International Conference on Luminescence
and Applications [ICLA-2019] organized by School
of Studies in Physics and Astrophysics, Pt.
Ravishankar Shukla University & Luminescence
Society of India (LSI) Co-organizers Department of
Physics, National Institute of Technology Raipur,
Govt. Science College, Raipur, Chhattisgarh, INDIA
on January 7-10, 2019.
Dr Ajit Joshi, Dr Sharad Patil, Dr B

Satnarayan and Dr Paresh N Patel
delivered Expert Talk in Intensive Crash
Workshop for Cracking IIT-JAM, JNU-
CEEB, Entrance Exam’s of Phase II
Sponsored by GSBTM
Dr. Sharad Patil has delivered a

plenary lecture as a Resource
person in the National Conference
on “Global Opportunities in
Chemical, Biological & Material
Sciences (GOCBMS)-2018” held on
28th & 29th December 2018.
26

Invited talk by faculty members
Dr. Sutapa Mondal Roy has presented an

Invited Lecture at “6th International
Conference on Natural Polymers”
organized by Center for Nanoscience
and Nanotechnology, Mahatma Gandhi
University, Kottayam, Kerala, on 7th – 9th
December, 2018.
Mr. Bhavin R. Patel was invited as Jury

Member for poster presentation
competition for UG and PG students
of Chemistry Department at V.S. Patel
College of Arts and Science Bilimora
on 29-12-2018.
Dr. Paresh N. Patel was called as eminent

speaker for state level two days
workshop on “Chemistry and
Mathematics for Biologist” organised by
President Science College, Gujarat
University, Ahmedabad, from 5th to 6th
July, 2018 which was sponsored by
GSBTM.
Dr Paresh N Patel was called as a Resource

Person for state level two days workshop
from 26th to 27th March, 2018 organised by
C. G. Bhakta Institute of Biotechnology,
UTU.
27

Additional activities by students and staff members
Apart from regular academic activities, we also organize several extra curricular as
well as co-curricular activates for the overall growth of the students. Where they can
get chance to show their hidden talent. Also they can get a chance to develop their
leader and managing skill.
In order to put hand together

with Gujarat Government
initiative as SSIP, we organised
a one day “Workshop for
Student Awareness about
Start-up to Business” on 18th
January 2019.
A session on ‘Interview
Skills & Resume Writing’
was conducted on the
18th of December 2018 at
the Manjula Hall by the
Centre of Humanities and
Development of the Uka
Tarsadia University (UTU).
Bhabha Atomic Research

Centre (BARC) & Uka Tarsadia
University (UTU) organized an
outreach programme on the
theme "Empowering India
through Atomic Energy" on
20th Dec 2018.
28

Additional activities by students and staff members
In honour to Dr Sarvepalli
Radhakrishnan and all the
teachers of the society,
Department of Chemistry,
UTU celebrated Teachers
day on 5th September,
2018.
In order to have live

demonstration about
industrial work
calture, final year PG
students have visited
IPCA Laboratories
Silvassa on 8th
September 2018.
To develop the bridge

between industries and
academia, Department
of Chemistry in
association with
Training & Placement
Cell of Uka Tarsadia
University organized
Academia–Industry
Interface 2018 (AII-
2018) on 18th August
2018.
Self-Defense Workshop
was organised by The
Center of Humanities
and Development, UTU.
29

Training and Placement Cell
Our training and placement partners…

30

National and International Events organized and hosted
54th Annual National Convention of Chemists-2017 jointly organized by Department of

Chemistry, Uka Tarsadia University, Surat (Gujarat-India) and Indian Chemical Society-
Kolkata during 23rd - 25th December –2017.
Academia- Industry Meet-2017 in collaboration with Southern Gujarat Chamber of

Commerce and Industry (SGCCI) on 21st February, 2017. 1000+ Students and
Faculties from various science colleges across Gujarat and delegates from industries
participated in the seminar.
31
Symposium and Research Scholar Meet in Allied Sciences
Patron
Shri Shailesh Patel Prof. D. R. Shah
President Provost
Uka Tarsadia University Uka Tarsadia University
Advisors Convener
Prof. G. Govil (TIFR, Bombay) Prof. K.R. Desai
Prof. A. K. Singh (IIT, Bombay) (UTU, Bardoli)
Secretary
Dr. Ajit Joshi
(I/C Director, Dept. of Chem., UTU)
Organising Secretaries
Dr. Paresh Patel, Dr. Sharad Patil
(Dept. of Chem., UTU)
Coordinators
Dr. Harishchandra Jirimali, Dr. Dharmesh Chejara
Dr. Pramod Patil, Dr. Satyanarayana Battula,
Dr. Anand Patel, Mr. Bhavin Patel
Organising Members
Dr. Parth J Naik Dr. Amrutlal Prajapat
Dr. Sutapa M Roy Dr. Nilesh Pandya
Dr. Chintan R Patel Dr. Jyoti Singh
Dr. Rajamouli Boddula Mr.Dipen H Desai
Mrs. Rutu D Patel Mrs. Nisha Odedara
Mrs. Meghna Panchal Ms. Shivani Tandel
Expert Talk by
Prof. G. Govil (TIFR, Mumbai)
Prof. A. K. Singh (IIT Mumbai)
Prof. K. P. Mishra (Ex-BARC, Mumbai)
Prof. Vimal KumarJain (UM-DAE-CEBS, Mumbai)
Prof. Prakash M. Bhate (ICT, Mumbai)
Prof. Atul Chaskar (Mumbai University)
Prof. Arnab Dutta (IIT Gandhinagar)
32
Symposium and Research Scholar Meet in Allied Sciences
TENTATIVE PROGRAM OUTLINE
DAY-1 (February 22, 2019);

Morning Venue: Pushpam Tarsadia Auditorium
09:00–10:00hrs Registration & Break Fast
10:00–10:30hrs Inaugural Ceremony
10:30–11:15hrs Technical Session – I
11:15–12:00hrs Technical Session – II
12:00–12:45hrs Technical Session – III
12:45–13:00hrs Photo session
13:00–14:00hrs Lunch
Post Lunch Venue: SRIMCA
14:00–16:00hrs Interactive Oral Presentation – I
16:00-16:15hrs Tea
16:00–18:00hrs Interactive Poster Presentation
DAY-2 (February 23, 2019); Venue: Manjul Auditorium
09:00–10:00hrs Break Fast
10:00–10:45hrs Technical Session – IV
10:45–11:30hrs Technical Session – V
11:30–12:15hrs Technical Session – VI
12:15–13:15hrs Lunch
13:15–14:45hrs Interactive Oral Presentations – II
14:45–15:00hrs Tea
15:00–16:00hrs Panel Discussion
16:00hr Valedictory
33
Invited Lecture
Prof. Girjesh Govil

President RSC (UK) Western Zone India
NASI Senior Scientist
Tata Institute of Fundamental Research
Mumbai
Physical methods in chemistry and biology
Several physical methods have been used in research and

industries in chemistry and biology. In fact, the entire
electromagnetic range has been used, starting from microwave to
gamma rays. The visible range is often used in estimates of
compounds in a mixture. However, the two important techniques
are nuclear magnetic resonance and X-rays. In my talk, I will
introduce the two techniques and then present their applications
in the following areas (a) basic research (b) applications in
chemical industries (c) applications in security and (d) human
health.
34
Invited Lecture
Prof. Anil Kumar Singh

Chairman, NASI Mumbai
Ex-HOD, Department of Chemistry, IIT Bombay
A Few Aspects of Chemical Biology
Lying in the overlap area between biology and chemistry, chemical

biology is a relatively new field of research. It deals with creation
and use of novel molecular tools and techniques to the study and
manipulation of biological systems. In one of the forms, chemical
biology involves application of chemical techniques, analysis, and
often small molecules produced through synthetic chemistry for
probing a biological system, or for use as speciality chemicals. This
aspect of chemical biology will be illustrated by discussing: i) the
nature of interactions at the reaction centre of retinal-binding
biological photoreceptors as probed by employing synthetic
analogues of retinal, ii) design and development of synthetic
caged compounds for spatially and temporally-controlled release
of bioactive compounds under physiological conditions, and iii)
development of chemical products including both novel molecules
and drop-in replacements using bioprivileged molecular approach.
The talk would accentuate on the concept and need behind the
use of bioprivileged molecules, which essentially are biology-
derived chemical intermediates and have brought in a new
paradigm in synthetic chemistry and chemical development.
Recent accomplishments in the field and future inroads into other
fields will also be highlighted.
35
Invited Lecture
Prof Prakash Bhate

Institute of Chemical Technology
Mumbai
Innovations in Colorants – Past and Present
This presentation will discuss some innovations that have taken

place in the field of colorants from 1857 when Perkin started
manufacturing the purple dye he accidently made a year earlier
to the development of dyes for inkjet printing. Other examples
include Perkin’s alizarin manufacturing process, development of
azoic colours, flush pigments, reactive dyes, nanofiltration and
diketopyrrolopyrrole pigments. Recent developments in the
author’s laboratory at ICT on reactive dyes based on diazonium
salts will also be discussed.
36
Invited Lecture
Prof. K.P. Mishra

Ex Bhabha Atomic Research Center, Mumbai-
400 085, India
Reactive oxygen species turn from friend to foe in cancer therapies
Reactive oxygen species (ROS) have amazing chemical properties and determine
the survival and death of both normal and cancer cells. There exists a delicate
balance between ROS and antioxidant defense in normal functioning of cells. A
pathological situation arises when there is imbalance between ROS and built in
defenses. Cancer cells are known to possess increased ROS level than that in
normal cells. Increased ROS are known to cause damage to DNA, proteins and lipids
which is reflected in the incidence of mutation in genes and alterations in other
vital cellular molecules leading to transformation and malfunctioning of cells. At
present point of time, it is widely accepted that ROS play a significant role in cell
homeostasis maintenance, signaling, tissue protection against external insults by
controlling cells proliferation through inducing apoptosis and defending against
cancer. ROS are capable of changing their roles in normal physiological functions,
induction of cancer (carcinogenesis) and in toxic responses of tumor cells to chemo
and radiotherapies. Thus at low and moderate levels ROS affect some of the most
essential mechanisms of cell survival such as proliferation, angiogenesis and tumor
invasion, at higher levels these agents can expose cells to detrimental
consequences of oxidative stress including DNA damage and apoptosis that result
in therapeutic outcomes on cancer. In more recent years, new knowledge has
accumulated to suggest that cancer treatment is often limited due to tiny amount
of cancer stem cells (CSC) in the core of tumor mass which are resistant to drugs
and radiation treatments. Interestingly, both normal and cancer stem cells,
maintain low ROS levels perhaps by augmenting endogenous antioxidants ensuring
their survival to therapies Evidently, understanding the new aspects on molecular
mechanisms and signaling pathways modulating creation and therapy of cancers by
ROS are critical in developing new and effective therapeutic strategies for cancer
treatments. This talk describes a general overview and rationale of paradoxical
action of ROS in creation and therapy of cancer including our research
contributions in this field.
37
Invited Lecture
Dr Atul Chaskar
National Centre for Nanosciences and
Nanotechnology, University of Mumbai
C-H bond Functionalization: A promising tool for synthesis of Key

building blocks for construction of complex Drug Candidates
In recent years, C-H bond functionalization has given a great impetus to

modern organic synthesis owing to the selective construction of new
carbon-carbon and carbon-heteroatom bonds leading to the rapid
assembly of complex molecular frameworks from easily available
simple starting materials. In these circumstances the power and
potential of C-H bond functionalization inspired domino strategies have
been demonstrated by synthesizing the library of medicinally important
heterocycles. In the context of sustainable organic synthesis, metal free
C-H bond functionalization and transition metal catalyzed C-H bond
activation are the most efficient, attractive, powerful and highly
desirable strategies. In recent years, I 2 in combination with DMSO has
proved to be an environment-friendly, metal-free effective system for
the series of organic reactions particularly in C–H functionalization. This
approach has emerged as an attractive tool in organic synthesis due to
its diverse applications. Considering this, we have synthesized various
key building blocks from easily available and prefunctionalized
multiform substrates.
38
Invited Lecture
Prof. Arnab Dutta

Chemistry Discipline, IIT Gandhinagar
Gujarat 382355
Inclusion of peripheral basic groups activates dormant
Cobalt-Salen like complexes for catalytic H2 production
The activity of the metalloenzymes is critically modulated by the

protein scaffold that tunes the electron and proton movements
along with the substrate around the metal active centre. However,
this unique outer coordination sphere feature is rarely considered
during the designing of synthetic catalysts. In our research group,
we have incorporated a minimal but essential outer coordination
sphere component around metal complexes. Following this
hypothesis, recently, we developed four complexes containing the
same Cobalt-Salen (Co-(N2O2)2] like core but have variable basic
functionalities on the periphery of the ligand structure. These basic
groups are derived from carboxylic acid (-COOH) or phenolic –OH,
which resemble the protein scaffold (i.e. outer coordination
sphere) in enzymes. Detailed electrochemical data exhibited that
the incorporation of these protic moieties around the complex has
activated the otherwise dormant Cobalt-Salen like core for
catalytic H2 production in aqueous solution. The presence of
carboxylic acid in two of those complexes enabled unique pH-
switchable catalytic H2 production, where the key role is played by
the pH-dependent metal-ligand interactions. The complementary
NMR and spectroscopic results indicated the formation of an
intricate hydrogen-bonding network by the basic functionalities
around the metal centre in presence of water. This highlights that
the rational inclusion of enzyme-inspired outer coordination
sphere features not only improve catalytic performance of an
already active catalyst, but also spark catalytic life even into an
otherwise inert metal core.
39
Abstract for Oral Presentation

40
ACCEPTED ABSTRACTS FOR ORAL PRESENTATION

Parallel Session – A (01:30pm to 03:30pm 22nd February 2019)
Venue: SRIMCA (Seminar Room - 01)
Oral Code Author Name Abstract Title Thrust Area
ABB-01 Dr Hiren Patel Bioprospecting and molecular Advances in

characterization of laccase producing Biotechnology /
bacteria from industrial contaminated Biochemistry
sites
ABB-02 Ms Jyotsnamayee Lock and Key mechanism of Protein Advances in
Nayak binding on conducting biomimetic Biotechnology /
polydopamine surfaces revealed by Biochemistry
Electrochemical Impedance
spectroscopy.
ABB-03 Dr Sushma Ijardar Liquid-liquid demixing of aqueous Advances in
solution of ionic liquids in presence of Biotechnology /
inorganic salts: Phase diagram and Biochemistry
application
DPC-01 Mr Ashish Raychura Utilization of the vegetable oil based Dyes & Polymer
polyol in the preparation of wood chemistry
protective polyurethane coating
DPC-02 Dr Mehul Khimani Self-assembly of thermo-responsive Dyes & Polymer
diblock copolymer in aqueous chemistry
solution
DPC-03 Mrs Nilam Patel Disperse Styryl and Azo Dyes for Dyes & Polymer
Polyester and Nylon Fiber Synthesis, chemistry
Optical Properties Having the 1,2,4-
triketo Naphthoquinone Skeleton.
DPC-04 Dr Rahulbhai “Synthesis and Characterization and Dyes & Polymer
Balvantbhai Physico-chemical Properties of chemistry
Tailor Homopolyamide Containing s-triazine
ring in the main chain”
DPC-05 Ms Reena Tondwal Drug (Quercetin) interaction with Dyes & Polymer
chitosan and functionalized chitosan chemistry
in acetate buffer-DMSO medium
through physicochemical properties
OIB-01 Dr Pallavi Jain Bidentate thiosemicarbazone and its Organic/Inorganic/Bio-
coordination complex: structure organic synthesis
elucidation and biological
investigation
OIB-02 Dr Rajamouli Boddula Experimental and Theoretical Organic/Inorganic/Bio-
Approach of TTA Antenna based organic synthesis
Tunable Light Emissive Eu(III)
Complexes for Versatile applications
41

Parallel Session – B (01:30pm to 03:30pm 22nd February 2019)
ENC-01 Dr Chirag Mistry Thermo gravimetric studies of Environmental

hydrothermally modified zeolitic chemistry
materials
ENC-02 Dr Hemangi Desai Examination of water quality pollution Environmental
generated due to leachate formation at chemistry
municipal solid waste landfill site.
ENC-03 Mr Himanshu Kohli Removal of Ethylparaben from Aqueous Environmental
Solution using Emulsion Liquid Membrane chemistry
ENC-04 Ms Pragya Singh Investigation of the kinetics of catalytic Environmental
ozone reaction using a manganese chemistry
catalyst
ENC-05 Dr Vaibhavkumar Metallic Nanoparticles: Simple analytical Environmental
Mehta toolbox for visual detection of trace level chemistry
metal ions
GC-01 Mr Bhavin Patel Expeditious synthesis of Oxirane Green chemistry
derivatives through the epoxidation of
coumarinyl chalcones under sonic
conditions
GC-02 Mr Chandra Bhushan Deep eutectic solvents and their Green chemistry
Triveni Pal applications
GC-03 Ms Dimpy Patel Combustion studies in liquid fuelled gas Green chemistry
turbine combustor
NPC-01 Ms Swati Sharma L-Alanine induced Thermally Stable Self- Natural products
Healing Guar gum hydrogel as Potential chemistry
Drug Vehicle for Sustained Release of
Hydrophilic Drug.
CP-01 Dr Neeraj Kumar Potential Noscapine Analogue designing Computational
and Pharmacological Evaluation chemistry
employing Chemoinformatics approach to
combat cancer associated tubulin protein
CP-02 Dr Sutapa Mondalroy Biological Activity of Some ACAT Inhibitors Computational
in the Light of DFT based Quantum chemistry
Descriptors
42

Parallel Session – C (01:30pm to 03:30pm 22nd February 2019)
MS-01 Dr Abhitosh Kedia Plasmonic Response of Anisotropic Gold Material Science

Nanostructures
MS-02 Dr Harishchandra Nanostructured Hydroxyapatite and Its Material Science
Jirimali Polymeric Composites: for Anticorrosive
Antimicrobial and Thermally Stable Coatings.
MS-03 Mr Lakhan Chaudhari Expired Pharmaceutical Drug as Corrosion Material Science
Inhibitor for Mild Steel in Acidic Media
MS-04 Ms Manita Das Engineered multifunctional nanoconjugates for Material Science
photothermal therapy and multi drug delivery
MS-05 Mr Mohammad Thermo-Switchable de Novo Ionic Liquid-Based Material Science
Muzammil Kuddushi Gelators with Dye- Absorbing and Drug-
Encapsulating Characteristics
MS-06 Dr Pratima Surati Synthesis, Characterization and Molecular Material Science
switching Performance of Photochromic
Edaraovone Derivative
MS-07 Dr Ramesh Sivasamy Synthesis, structure, electronic structure, Material Science
optical, and magnetic properties of Pd/
Mn(Mn1.36Pd0.64)O4 nanocomposite
MS-08 Dr Surati Kirankumar Highly Effcient Red Heteroleptic Ir(III) complexes Material Science
R. for OLEDs Application
MS-09 Ms Yachana Application of vitamin B6 cofactor conjugated Material Science
Upadhyay BSA-CdS QDs for the fluorescence recognition of
alkaline phosphatase
43

Parallel Session – D (01:30pm to 03:30pm 22nd February 2019)
Venue: SRIMCA (Shrimad Hall)
OIB-03 Dr Garima Pandey Synthesis and spectral studies of Co and Organic/Inorganic/Bio-

Ni complexes of Diacetato-bis-(p- organic synthesis
methoxy phenyl carbonyl azomethine
benzene sulphanilamide
OIB-04 Mr Gaurang Bhatt Ru-catalyzed unusual benzylic oxidation Organic/Inorganic/Bio-
of Dodecahydrotriphenylene organic synthesis
OIB-05 Mr Gaurangkumar DBU-Catalyzed Domino-Aldol-hetero- Organic/Inorganic/Bio-
Brahmbhatt Diels-Alder Reaction in Glycerol: Efficient organic synthesis
Synthesis of Tricyclic Pyrano[3, 4-
c]chromenes
OIB-06 Dr Jyoti Singh “Electrochemical study of mixed ligands Organic/Inorganic/Bio-
biomimetic complexes of In(III) with organic synthesis
succinic and amino acids.”
OIB-07 Ms Mousam Patel Terpyridine based Photoluminescence Organic/Inorganic/Bio-
Lanthanide Metal Complexes as organic synthesis
Photodynamic Therapy
OIB-08 Dr Pramod Kulkarni Sulfanilic acid catalysed one pot three Organic/Inorganic/Bio-
component mannich reaction for organic synthesis
synthesis of ß- amino ketones
OIB-09 Ms Pratibha Prasad Synthesis And Pharmacological Studies of Organic/Inorganic/Bio-
Imidazo[1,2- a]Pyrimidine Derivatives Of organic synthesis
Imidazole/Triazole Clubbed Pyrazole
OIB-10 Dr Sampatrao Synthesis of 2’, 6’-Dihydroxy Chalcone Organic/Inorganic/Bio-
Suryawanshi Using Lithium Hydroxide as a Base organic synthesis
OIB-11 Dr Satyanarayana 2-Oxo Group Driven Chemistry in a- Organic/Inorganic/Bio-
Battula Hydroxyphosphonates organic synthesis
OIB-12 Mr Vishal Khomane Optimization of Ultrasound Assisted Organic/Inorganic/Bio-
Reactive Crystallization of Strontium organic synthesis
Sulfate.
OIB-13 Mr Yogesh Walunj An Efficient Synthesis of Ethyl 2, 4-Dioxo- Organic/Inorganic/Bio-
4-Aryl/Alkyl Butanoate Under Thermal organic synthesis
and Microwave Conditions.
44

Session – E (02:00pm to 03:30pm 23rd February 2019)
Venue: Manjula Auditorium
CC-03 Mr Tanmay Theoretically Inspired Electro Optic Computational

Dashaputre Chromophores with Substituent Chemistry
Changes in the first order ?(Beta)
Values
MS-10 Mr Bhausaheb Patil Synthesis and Characterization of Material Science
Triazolopyridine and Pyrrolo
Quinoxaline Based Bipolar Host
Materials for Phosphorescent
Organic light Emitting Diodes
(PhOLEDs)
MS-11 Dr Someshwar Pola Synthesis of New Pd (II) Complexes Material Science
for Oxidative-Cyclization Reactions
under Visiblie-light-driven
OIB-14 Dr Jawahar Jat Direct N-H/N-alkyl Aziridination of Organic/Inorganic/
Alkenes Bio-organic
synthesis
OIB-15 Mr Sachin Pardeshi NOVEL SYNTHETIC METHODS FOR Organic/Inorganic/
ONE POT CASCADE SYNTHESIS OF Bio-organic
MULTISUBSTITUTED IMIDAZOLES synthesis
OIB-16 Dr Tushar Shinde Immobilization of ruthenium Organic/Inorganic/
catalysts on inorganic support and Bio-organic
testing thereof in cardanol synthesis
metathesis.
45
Immobilization of ruthenium catalysts on inorganic support

and testing thereof in cardanol metathesis
Tushar Shinde, Hynek Balcar
SVKM’s Institute Of Technology, Dhule, Survey No. 499, Plot No 02, Behind Gurudwara,
Mumbai Agra National Highway, Dhule -424 001, Maharahstra, India
Grubbs second generation (GII) and Hoveyda-Grubbs type catalysts (ZC) are well known
metathesis catalysts for their high activity and tolerance to the heteroatoms in substrate
molecules.[1] An idea behind this work is to immobilize the ZC and GII, on SBA-15 (SBET =
863 m2/g, V = 0.920 cm3/g, D = 6.8 nm) and to apply these hybrid catalysts in cardanol
metathesis and cardanol cross metathesis with ethene and cis-1,4-diacetoxy-2-butene
(DAB). The ZC catalyst was attached to the sieve surface by non-covalent interactions[2] and
GII catalyst was attached to the surface via phosphine linkers.[3]
R=
OH
N N N N
Cl Cl
Ru Ru O
R Cl Ph Cl
P O S N
Ethene DAB O
OH OH
Grubbs II generation catalyst ZC

(GII)
Scheme 1: Cardanol Cross Metathesis
Cardanol cross metathesis is depicted in the Scheme 1. There are two reasons for the study
of cardanol metathesis. Firstly, CNSL are produced in a large quantity but chemical
transformations of cardanol are not much known. Secondly, as a natural product it may
serve as a renewable source of phenolic compounds. The given hybrid catalysts proved to be
active in cardanol metathesis even without protecting OH groups. In metathesis of cardanol
high conversion (78%) was obtained by using ZC/SBA-15. Both ZC/SBA-15 (1 wt % Ru) and
GII/SBA-15 (0.3 wt% Ru) catalysts proved to be highly active and selective in cardanol cross
metathesis with ethene and DAB, however Ru leaching was lower in case of GII/SBA-15
(0.5% with respect to the original content of Ru) as compared to ZC/SBA-15 (2.5%). The low
Ru leaching gives an opportunity for obtaining products free of catalyst residues with
applications as a detergent precursor and as fragrance and flavor agents.
References:
1 Grubbs, R. Angew. Chem. Int. Ed., 2006, 45, 3760-3765.
2. Balcar, H.; Shinde, T.; Žilková, N.; Bastl, Z. Beilstein J. Org. Chem. 2011, 7, 22-28.
3. Bek, D.; Balcar, H.; Žilková, N.; Zukal, A.; Horáček, M.; Čejka, J. ACS Catal. 2011, 1, 709-718.
46
2-Oxo Group Driven Chemistry in α-Hydroxyphosphonates

Dr Satyanarayana Battula
Department of chemistry, Uka Tarsadia University, Bardoli, Surat, Gujarat-394350
A well known Pudovik reaction requires the assistance of either acid/ base catalyst to
produce α-hydroxyphosphonates from aldehydes and dialkyl phosphates/ H-
phosphonates. The same reaction occur in absence of catalyst when aldehyde with the
environment of 2-oxo group in 2OA. The resultant α-hydroxy-β-oxophosphonates
(HOP), unlike regular hydroxyphosphonates, display variety of transformations into
various products oxoesters, phosphates and acids respectively at various conditions.
This typical behavior is owing to enhanced electrophilicity of HOP by the presence of 2-
oxo group which is enough able to switch the reactions in diverse directions at various
conditions.
Synthesis, Characterization and Molecular switching

Performance of Photochromic Edaraovone Derivative
Pratima R. Surati*a and Bhavna A. Shahb
aM.L. Parmar Science College,Masma, Surat-394540,Veer Narmad South Gujarat University,
Gujarat, India.
A new Schiff base compound 4[(1,5-Dimethyl-3-oxo-2-phenyl-pyrazolidin-4-ylimino)-

phenyl-methyl]-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one (PMBP-4AAP) was
synthesised and characterized by elemental analyses, LC-MS, FTIR and 1 H-NMR spectra.
The photochromic property of the synthesised compound investigated under 365 nm
UV-light irradiation, which can be observed with solid state absorption spectra. The
photoisomerization is due to photoinduced intermolecular hydrogen bond, which
results in enol to keto transformation. The binding studies shows good selectivity with
Ni(II). The Photo switching behaviour was studied in solution, which reveals the
sensing can be photo controllable. The logic behaviour was investigated for Ni (II) in
acidic media for two input system (Ni+2 and H+ ) using the UV absorption spectra, which
shows NOR logic gate behaviour.
47
Synthesis, structure, electronic structure, optical, and magnetic

properties of Pd/ Mn(Mn1.36Pd0.64)O4 nanocomposite
Ramesh Sivasamy, PotuVenugopal and Rodrigo Espinoza
Saveetha University, Pondicherry University, University of Chile
Herein, we synthesize the Pd/ Mn(Mn1.36Pd0.64)O4 nanocomposite using the facile sol-
gel technique and the structure, morphology, optical, electrochemical and magnetic
properties were elucidated. The composite formation, phase identification and
crystalline structures of the cubic crystalline Pd and Mn(Mn1.36Pd0.64)O4 nanoparticles
of the composites were confirmed by the X-ray diffraction. Porous and nanosized
globular shape morphologies were revealed using SEM and TEM images. The observed
optical band gap from the diffuse reflectance spectra is found to be 2.22 eV.
Electrochemical performance was estimated from the cyclic voltammetric analysis. The
Symmetric nature of the voltammetry cure shows that the nanocomposite is a promising
entrant for fast redox reactions with enhanced specific capacitance. Magnetization curve
explores the paramagnetic behavior of the samples at room temperature. Band structure
and spin-polarized partial density of states of Mn(Mn1.36Pd0.64)O4 crystal structure
confirm the half-metallic and magnetic behavior.
Deep eutectic solvents and their applications

Chandra Bhushan T. Pal and Girirajsinh C. Jadeja*
Chemical Engineering Department, SVNIT, Surat - 395007, Gujarat, India
Phytochemicals are still traditionally extracted by noxious petro-derived solvents, such

as methanol, ethanol, acetone, hexane, etc. Traditional methods such as Soxhlet
extraction, percolation are very time consuming and require relatively large amount of
solvents. There is an increasing demand for novel extraction techniques with shortened
extraction time, reduced organic solvent consumption and increased pollution
prevention. Novel extraction methods like Pressurized Liquid Extraction (PLE),
Ultrasound Assisted Extraction (UAE), Microwave Assisted Extraction (MAE), Deep
Eutectic Solvents (DESs), Ionic Liquids (ILs) etc., which are fast and efficient for
extracting phytochemicals, are gaining popularity. One of the novel green extraction
techniques, DESs is used for the purpose of extracting polyphenols in the present
research work. Deep eutectic solvents are now widely acknowledged as a new class of
ionic liquid (IL) analogues because they share many characteristics and properties with
ILs. The terms DES and IL have been used interchangeably in the literature though it is
necessary to point out that these are actually two different types of solvent. DESs are
systems formed from a eutectic mixture of Lewis or Brønsted acids and bases which can
contain a variety of anionic and/or cationic species; in contrast, ILs are formed from
systems composed primarily of one type of discrete anion and cation. In recent years,
deep eutectic solvents (DESs) have been considered green solvent alternatives to
conventional solvents and have attracted considerable attention.
48
Highly Efficient Red Heteroleptic Ir(III) complexes for OLEDs

Application
Meha J Prajapati, K. R. Surati
Department of Cheistry, Sardar Patel University, Vallabh Vidyanagar 388120, Anand,
Gujarat, India
Three heteroleptic complexes of Ir(III) I-III were synthesized and characterized by

spectroscopic techniques. Electrochemical and photophysical properties of the
complexes were measured by cyclic voltammetry, UV-visible and luminescence spectra.
These complexes show band gap in the range of 1.97 – 2.0 ev with the highest occupied
molecular orbitals (HOMO) and lowest unoccupied molecular orbitals (LUMO) around
-5.60 and -3.61 ev. Whereas the photoluminescence spectra were shows λPL at 602 nm.
with the luminescence quantum yield 44.2 to 52.9 %. Thermal properties of all the
complexes were measured and they are stable upto 300 C. These characteristics of the
complexes useful to utilize them for OLED fabrication. The device fabricated with the
device structure ITO/HAT-CN/TAPC/CBP-I or II or III/TPBi/LiF/Al. The fabricate device
doped with 10% complex shows a high luminous efficiency of 6.6 cd/A, maximum
external quantum efficiency of 6.67% at 4 V, maximum outstanding luminance of 12950
cd/m2, and maximum power efficiency of 5.6 lm/W with Commission Internationale de
L’Eclairage (CIE) coordinates of (0.67, 0.33).
Removal of Ethylparaben from Aqueous Solution using Emulsion

Liquid Membrane
Himanshu P. Kohli, Mousumi Chakraborty, Smita Gupta
Department of Chemical Engineering, Sardar Vallabhbhai National Institute of Technology,
Surat, Gujarat 395007, India.
Ethylparaben (EP) being the esters of p-hydroxybenzoic acid is an endocrine disrupting

compound which hinders the glandular action and hormone production. It is still detected
in river water samples even after the treatment by conventional methods. In the current
study, Emulsion Liquid Membrane (ELM) consisting of Span 80 as surfactant,
trioctylamine (TOA) as carrier, n-heptane as diluent and sodium carbonate (Na2CO3) as
the stripping solution was used for the removal of ethylparaben from aqueous solution.
Investigations were carried out to observe the influence of several operating parameters
like carrier type and its concentration, stripping phase type and its concentration, speed of
homogenizer, surfactant concentration and volume ratio of membrane to stripping
solution on the extraction of EP. Impact of homogenizer speed on emulsion droplet size
were studied through microscopic images. Stability of the emulsion was detected by
Turbiscan. Atomic force microscopy (AFM) analyzed the dimensions and shape of
emulsion droplet. Fourier transform infrared (FTIR) spectroscopy confirmed the bonding
and presence of different functional groups. By means of a stable emulsion, ~90% removal
of EP was attained at optimum conditions.
49

Thermo-Switchable de Novo Ionic Liquid-Based Gelators with
Dye-Absorbing and Drug-Encapsulating Characteristics
Muzammil Kuddushi, Nehal K. Patel, Sargam Rajput, Ankit Shah, Omar A. El
Seoud, and Naved I. Malek
Applied Chemistry Department, S. V. National Institute of Technology, Surat 395007
Gujarat, India
An ionic liquid-based surfactant with ester functionality self-aggregates in an aqueous

medium and forms ionogels at 8.80% (w/v) concentration at physiological pH. The
ionogel exhibited a remarkable change in its appearance with temperature from
fibrillar opaque to transparent because of the dynamic changes within its
supramolecular structure. This gel-to-gel phase transition occurs below the melting
point of the solid ionic liquid. The ionogels were investigated using turbidity,
differential scanning calorimetry, scanning electron microscopy (SEM), field emission
SEM (FE-SEM), inverted microscopy, transmission electron microscopy imaging,
Fourier transform infrared spectroscopy, rheological measurements and small angle
neutron scattering (SANS). The fibrillar opaque ionogel and transparent ionogel were
studied for their ability to absorb dyes (methyl orange and crystal violet) and to
encapsulate drugs (diclofenac sodium and imatinib mesylate).
Combustion studies in liquid fuelled gas turbine combustor

Patel Dimpy A, Poonawala T. Y, Kulshreshtha D. B.
Technical Surveyor, JPAL Associates, Surat, Research Assistant, SVNIT, Surat
Associate Professor, MED, CKPCET, Surat
The combustor is designed developed and experimentally investigated using

Ethanol as fuel. The chamber is experimentally optimized and operated at different
equivalence ratio. The results show stable combustion which was a primary
objective of present combustor. The temperature levels obtained are 1400 K at
centerline. However, due to non-availability of sophisticated instruments pressure
and temperature at walls were not conducted.
50
Optimization of Ultrasound Assisted Reactive Crystallization of

Strontium Sulfate
Vishal D. Khomane
CGIPT , Uka Tarsadia University, Gujarat
Strontium sulfate is main source of strontium element and its widely used in various
manufacturing industries in the form of nano range crystal size such as ceramic,
cosmetic, textile, paint etc. In present work ultrasound assisted reactive crystallization
process has been used to produce strontium sulfate from strontium chloride
hexahydrate, sodium sulfate and ethylene disodium salt dihydrate (EDTA). For this
purpose various operating parameters such as equimolar concentration of reactant,
temperature, EDTA concentration, ultrasound amplitude and ultrasound duration have
studied in details for percentage yield and crystal size. Multi-response optimization for
maximization of percentage yield and minimization of the crystal size was done by using
taguchi method with grey relational analysis. The optimize condition obtained 0.02M
equimolar concentration of reactant, 30oC temperature, 50mg of EDTA concentration,
50% ultrasound amplitude and 20min ultrasound duration. At the multi-response
optimized condition resulted to 91 percentage yield and crystal size 615.1nm. Compare
to conventional process large amount of percentage yield increase with relatively
smaller size of crystals observed in multi-response optimized experiment.
Application of vitamin B6 cofactor conjugated BSA-CdS QDs for the

fluorescence recognition of alkaline phosphatase
Yachana Upadhyay, Shilpa Bothra, Rajender Kumar and Suban K Sahoo *
Department of Applied Chemistry, SVNIT, Surat-395007, Gujarat, India
This manuscript presents a novel nanosensor system for the rapid detection of alkaline
phosphatase (ALP) activity in biological samples. The nano-assembly was designed by
functionalizing vitamin B6 cofactor pyridoxal 5’-phosphate (PLP) over the surface of
BSA stabilized CdS quantum dots through the interaction of free amine present in BSA
with the aldehyde group of PLP. Upon addition of ALP, the functionalized PLP
converted to pyridoxal followed by the emission of QDs was restored. Without any
noticeable interference other tested bioactive analytes, this nano-assembly can be
applied to detect ALP activity down to 0.09 U/mL and also successfully tested to
determine the ALP activity in in real water and biological samples such as human
serum plasma with good recoveries.
51
Nanostructured Hydroxyapatite and Its Polymeric Composites: for

Anticorrosive Antimicrobial and Thermally Stable Coatings
Dr. Harishchandra D. Jirimali
Department of Chemistry, UkaTarsadia University, Maliba Campus, Gopal-Vidya Nagar
(Surat) Guarat 394350 India
Hydroxyapatite (HAP) (HAP; Ca5(PO5)3OH is one of the important bio-inorganic

materials found in the bones and skeletons of the several organisms. The important
properties of the Nano-HAP such as biocompatibility, affinity towards the biopolymers
and high surface area made its applicable in various fields like bone tissue engineering
environmental applications, control drug delivery systems and anticorrosive coatings etc.
The synthetic sources of calcium are usually used for the production of HAP and its
derivatives. The waste egg shells, Mollusc Shells are the biological source of the calcium
and worldwide available abundantly, so it can be a cheaper material for the production of
HAP. The utilization of the waste eggs shells for the preparation of useful biocompatible
nanostructured HAP automatically solve the environmental issue of disposal of the waste
egg shells and its large quantity can be used in the polymer nano-composite preparation
for the anticorrosive coating applications. The Nanomaterials like CNT and GO can be
decorated with the hydroxyapatite and utilised in the polymer composite preparation.
Silver doped HAP is used in the antimicrobial and anticorrosive coating applications. The
properties of the polymers like LLDPE and natural polyols can be improved by addition
of hydroxyapatite nano particles in the polymeric matrix. The Hydroxyapatite polymer
composites can be used in the catalysis, anticorrosive and antimicrobial coatings and fire
resistant coatings.
Electrochemical study of mixed ligands biomimetic complexes of

In(III) with succinic and amino acids
Dr. JYOTI SINGH
Department of Chemistry, UkaTarsadia University, Maliba Campus, Gopal-Vidya Nagar
(Surat) Guarat 394350 India
Biomimetic complexes are getting importance in the field of biosensors, bio-fuel cells,
artificial photosynthesis and bio-catalysis due to their high stability. In the present
study In(III) complexes with the succinic acid and some amino acids (Serine and
Glycine) were synthesised. The prepared complexes were characterized
electrochemically at the dropping mercury electrode (DME) at constant ionic strength
KNO3 (μ = 1.0 M) and 308 OK temperature. Triton X-100, (0.002%) was used as
maximum suppressor. The complexes of In(III) showed a reversible electrochemical
behaviour and diffusion controlled electron transfer phenomena involving three
electrons. A cathodic shift in half-wave potential is observed as a function of glycine
concentration. The magnitude of the shift in half-wave potential is greater in presence
of glycine and serine than obtained for simple In(III)-succinic acid system. Overall
formation constant calculated by Schaap and Mc-Master.
Keywords: CL-362 Polarographic analyser, In(III),succinic acids ,amino acids.
52
Biological Activity of Some ACAT Inhibitors in the Light of DFT

based Quantum Descriptors
Dr. SUTAPA MONDAL ROY
Department of Chemistry, Uka Tarsadia University, Maliba Campus, Bardoli 394350,
Gujarat
The biological activity of a series of homologue molecules may be quantitatively

represented in terms of their structural descriptors through a mathematical relationship,
known as the quantitative structure activity relationship (QSAR). The determination of
biological activity or toxicity of a series of compounds through experiments often find
difficulty in terms of time, cost and availability of sources associated with it. Along this
line, the proper utilization of QSAR methodology saves resources for the development of
new molecules and drugs. A significant amount of effort has been tendered for
developing various descriptors to address reliable prediction of biological activity of
different important compounds. The types of developed descriptors include geometrical
parameters, topological index, electronic properties, and electrophhilicity index, philicity,
charge transfer (∆N), Fukui function etc. as quantum chemical descriptors.
A detail investigation is performed for a series of twenty four aminosulfonyl carbamates
as acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitors. The biological activity of
aminosulfonyl carbamates in terms of log (IC50) has been estimated by developing
suitable quantum chemical descriptors in the light of density functional theory. In order
to identify potential descriptors, In order to understand inhibitor-biosystem interactions,
a model biosystem is considered which comprises of five nucleic acid bases. Accordingly,
two global descriptors, viz. electron affinity (EA) and energy transfer during the
interaction between inhibitors and biosystems (∆E), and a local descriptor, viz. group
atomic charges on sulfonyl moiety (  QSul) are developed toward understanding bio-
activity of aminosulfonyl carbamates. It is noteworthy to achieve that the three-

parameter regression model for considered parameters EA, ∆E and QSul is observed to
predict more than 94% activities of aminosulfonyl carbamates in terms of log(IC50). The
developed regression model is also statistically validated and successfully tested for a
series of unknown compounds.
Utilization of the vegetable oil based polyol in the preparation of

wood protective polyurethane coating
Ashish J. Raychura, Smita Jauhari and Bharatkumar Z. Dholakiya
Department of Applied Chemistry, Sardar Vallabhbhai National Institute of Technology
(SVNIT), Surat - 395 007, Gujarat, India
Polyurethanes have gain a lot of significance due to its wide range of application.
Generally most of the diols or polyols used for the polyurethane synthesis are
synthesized from petroleum resources. By keeping environmental aspect in mind, the
current work reports the synthesis of polyol from vegetable oil. The structure of the
synthesized polyol was confirmed by the spectroscopic techniques and it was further
used in the preparation of wood protective polyurethane coating. The coating
performance of the prepared wood coating was evaluated by the measurement
mechanical, thermal and chemical properties.
Keyword: Coating, Polyol, Polyurethane Vegetable oil, wood.
53
Examination of water quality pollution generated due to leachate

formation at municipal solid waste landfill site
Mr. Yogesh Maurya and *Dr. Hemangi Desai
TIFAC-CORE in Environmental Engineering, SCET-Surat and
*Shree Ramkrishna Institute of Computer Education and Applied Science, Surat
The burial of municipal solid waste in landfills is the most common disposal alternative in
most countries. Landfill leachate is generated by excess rainwater percolating through the
waste layers in a landfill. A combination of physical, chemical, and microbial processes in the
waste transfer pollutants from the waste material to the percolating water. An
understanding of leachate composition is critical for making projections on the long-term
impacts of landfills. To know the amount of pollution five sampling locations were decided:
In the study, these five samples were analyzed in the laboratory for the parameters namely
Phosphate, Nitrite, Nitrate, Chloride, Fluoride, Alkalinity, TDS/TSS, Ammonia, Ammonical
Nirogen, Iron, COD, Phenol. From the result of analysis, the leachate sample was found to
have the maximum pollution in it, the mixture sample was taken from the place where the
leachate used to get accumulate in the Auranga river, and the sample of Auranga river was
taken a bit far from that place of MSW disposal site to know about the amount of pollution
created by this leachate in the Auranga river. The parameter of underground water was
analyzed by comparing it with drinking water standard and underground water from other
place where there was no site of solid waste. By examining analytical results it is clearly seen
that Nitrate(90), Phenol(7.2), Iron(446.8), Alkalinity(1800), Ammonical Nitrogen(178.2),
COD (1560) parameters in the mg/L (concentration), found above the inland surface water
discharge standards, are responsible for polluting the Auranga river as well as ground water
at the disposal site nearby Auranga river. Whereas the water sample taken from residential
area, far away from MSW-leachate site, is free from pollution. The results from data analysis
show that, the water is certainly unfit for drinking purpose without any kind of treatment,
even for other surface water usage purposes, it could not be considered quite acceptable.
Thermo gravimetric studies of hydrothermally modified

zeolitic materials
Chirag B. Mistrya*, Bhavna A. Shahb, Mayank Chapaneriyaa
aBhagwan Mahavir College of Science & Technology, Bharthana road, Vesu, Surat-395017
bDepartment of Chemistry, Veer Narmad South Gujarat University, Surat-395007
The present study reports the thermal degradation of zeolitic materials. The key starting
material is Bagasse Fly Ash (BFA) which is an agricultural detritus. The zeolitic material
was synthesized viz. Conventional Zeolitic Bagasse Fly Ash (CZBFA) and Electrolyte
treated Conventional Zeolitic Bagasse Fly Ash (ECZBFA) from BFA using hydrothermal
method. The thermal study will focus on the thermal characteristics of the sorbents in the
form of the kinetic parameters of the thermal degradation. The Coats and Redfern method
has been employed for estimation of various kinetic parameters viz. order of
decomposition (n), energy of activation (E*), pre-exponential factor (A). The other
thermodynamic parameters also carried out using thermal degradation data viz. entropy
of activation (S*), enthalpy of activation (H*) and free energy of activation (G*). The
results of thermodynamic analysis shows that the native BFA shows higher activation
energy than that of CZBFA and ECZBFA.
Key words: zeolitic materials, TGA, Thermal degradation, Coats and Redfern method.
54
Expeditious synthesis of Oxirane derivatives through the

epoxidation of coumarinyl chalcones under sonic conditions
Bhavin R. Patela* , Jignesh P. Ravalb
a*Department of Chemistry, Uka Tarsadia University, Maliba Campus, Bardoli-394
350, Gujarat, INDIA, bMandvi Education Society (TMES), Mandvi, Dist: Surat,
Gujarat, INDIA
Oxiranes can serve as versatile precursor in the synthesis of natural products and drug
molecules and are considered as important intermediates in synthetic organic chemistry.
This information leads in development of methodologies allowing the epoxidation of
carbon–carbon double bonds. The most efficient methods used for this purpose is
epoxidation of chalcone. We employed urea hydrogen peroxide as epoxidant and
epoxidation of coumarinyl chalcones was carried out to afford the titled compounds.
Ultrasound accelerate many organic reaction and this prompts us to investigate the
reaction using Ultrasound technique and the reaction was carried out in shorter reaction
time (15-45 minutes) with high yield (71-90%). This method is found to be
advantageous in terms of mild conditions, no toxic solvents used, especially; the reaction
time is much shorter compared with the conventional method.
Keywords: Oxiranes, Coumarinyl Chalcones, Epoxidation, Ultrasound.
Terpyridine based Photoluminescence Lanthanide Metal

Complexes as Photodynamic Therapy
Mousam H Patel and Paresh N Patel*
Laboratory of Bioorganic Chemistry, Department of Chemistry, UkaTarsadia
University, Bardoli – 394 350, Gujarat, India
Lanthanide metal complexes are of increasing interest as photosensitizers in

photodynamic therapy (PDT) and, more recently, for photochemotherapy (PCT). In
recent years, Ru(II) polypyridyl complexes have emerged as promising systems for
both PDT and PCT. Their rich photochemical and photophysical properties derive from
a variety of excited-state electronic configurations accessible with visible and near-
infrared light. Octahedral/Square planer complexes of Eu(III), Tb(III) and Gd(III) with
terpyridine ligands were synthesized and characterized by IR, 1 H NMR, 1 H-1 H COSY, 13 C
NMR, mass spectral analyses, single crystal XRD data and thermo gravimetric analysis.
The lanthanide complexes of terpyridine ligands are more rigid than other tridentate
ligands, and have several synthetic and structural advantages over other lanthanide
complexes. These complexes have not been investigated systematically for their bio-
interaction. Briefly, presentation summarizes the challenges to bringing PDT into
mainstream cancer therapy. It considers the chemical and photophysical solutions that
lanthanide metal complexes offer, and it puts into context the multidisciplinary effort
needed to bring a new drug to clinical trial.
Reference: Susan Monro, et al.,

Chem. Rev. 2019, 119, 797−828
55
Self-assembly of thermo-responsive diblock copolymer

in aqueous solution
Dr. Mehul Khimani
School of Science, P. P. Savani University, NH-8, GETCO, Near Biltech, Village: Dhamdod,
Kosamba, Dist., Surat 394125, Gujarat, India
Stimuli responsive neutral-b-ionic diblock copolymers were synthesized by RAFT

polymerization and characterized by NMR and GPC. The aggregation behavior of these
copolymers was examined by turbidity, DLS, and SANS as a function of temperature, pH,
presence of salts and surfactant. Turbidimetry data showed that block copolymers
remain as molecularly dissolve in water below the lower critical solution temperature
(LCST) of neutral block, however they form aggregates/micelles with neutral block at
higher temperature. The cloud point temperature (CPT) of copolymers decrease in the
presence of NaCl and opposite charge surfactant but increases with increase in DP
(degree of polymerization) of ionic block copolymer and pH. DLS data also support the
turbidity results. The copolymers showed larger aggregates in presence of additives.
Small angle neutron scattering (SANS) data conﬁrm the formation of worm- or thread-
like micelles in the presence of oppositely charged surfactant.
Novel synthetic methods for one pot cascade synthesis of

multisubstituted imidazoles
Sachin D. Pardeshi 1,a, Atul C. Chaskar *,a
aNational Centre for Nanosciences and Nanotechnology, University of Mumbai,
Imidazoles is a privileged azaheterocycle, an ubiquitous component in various natural

products and pharmaceuticals. A convenient and an effective synthesis of
multisubstituted imidazoles utilizing arylacetic acids, N-arylbenzamidines[1,2] and
styrene[3] has been developed. The use of inexpensive catalysts as well as oxidant and
readily available starting materials makes this protocol environmentally friendly and
economically viable. The multisubstituted imidazoles were obtained in moderate to
good yields with significant functional group tolerance and high regio selectivity using
this protocol
REFERENCES:
[1] S. D. Pardeshi, K. S. Vadagaonkar, J. J. Lade, L. Melone, A. C. Chaskar, chem. select., 2017, 2 , 5409. [2] S.
D. Pardeshi, P. A. Sathe, K. S. Vadagaonkar, L. Melone, A. C. Chaskar, Synthesis., 2017, 50, 361.[3] S. D.
Pardeshi, P. A. Sathe, K. S. Vadagaonkar, A. C. Chaskar, Adv. Synth. Catal., 2017, 359, 4217.
56
Metallic Nanoparticles: Simple analytical toolbox for

visual detection of trace level metal ions
Vaibhavkumar N. Mehta1, Rameshchandra M. Patel1 and Suresh Kumar Kailasa2
1 Aspee Shakilam Biotechnology Institute, Navsari Agricultural University, Ghod-dod Road,
Surat; 2 Applied Chemistry Department, SVNIT, Surat-39507
Nowadays, metal pollution has become a major concern in ecology in the world. Metal ions
such as Cu2+ , Hg2+ , Pb2+ , Cd2+ , Al3+ , Mn2+ and Co2+ exhibit toxic nature even at trace levels,
inhibiting various biochemical pathways in the living systems. Therefore, there is a big
challenge to analytical chemists to develop a facile, sensitive and selective analytical
methods for real-time monitoring of trace level metal ions at minimal sample volumes.
Since the traditional analytical techniques (ICP-MS, XRF, ICP-AES etc) are very expensive,
laborious, and time consuming, and importantly they required tedious sample pre-
treatment prior to their identification by analytical technique. In this connection, metallic
nanoparticles (Au and Ag NPs) have shown remarkable performance in developing
miniaturized analytical platforms for colorimetric detection of wide variety chemicals due
to their unique physico-chemical properties which mainly depends on the size of NPs due
to their surface plasmon resonance (SPR). To tune their recognition ability towards specific
metal ion, gold and silver nanoparticles have been modified with various dithiocarbamate
derivatives and used as probes for the colorimetric detection of heavy metal ions (Cu2+,
Hg2+ , Pb2+ , Al3+) via aggregation mechanism. Functionalized Au and Ag NPs were
characterized by UV-visible, FT-IR, TEM and DLS. The specific metal ion has shown great
ability to induce colour change and SPR peak shift of functionalized metal NPs, showing
wider linear range with lower detection limits from micro molar to nanomolar range. The
develop methods are free from interference and exhibited good accuracy and precision. The
developed probes were successfully utilized for the rapid, selective and sensitive detection
of heavy metal ions in drinking, tap, canal and river water samples. Overall, colorimetric
sensing ability of Au and Ag NPs was successfully tuned by modifying their surfaces with
different dithiocarbamate derivatives.
An Efficient Synthesis of Ethyl 2, 4-Dioxo-4-Aryl/Alkyl

Butanoate Under Thermal and Microwave Conditions.
Yogesh S. Walunj,1,2 Pravin Mhaske,2 Pramod Kulkarni,1 Jayashri Jasud,1 Sharmila
Walunj 1
1. Post Graduate Centre in Orgaanic Chemistry ^&Department of Chemistry, Hutatma
Rajguru Mahavidyalaya, Rajgurunagar. 2.Research Centre in Chemistry, S.P. College, Pune.
Affiliated to Savitribai Phule Pune University, Pune.
An efficient method for synthesis of ethyl 2, 4-dioxo-4-aryl/alkyl butanoate has been

developed under thermal and microwave conditions. We prepared ethyl 2, 4-dioxo-4-
aryl/alkyl butanoate by the reaction between substituted acetophenone/cycloalkyl
ketones with diethyl oxalate in presence of ≈ 21% ethanolic solution of sodium ethoxide
in ethanol under thermal condition and solvent free under microwave condition. The
yield of reaction is moderate to high under both conditions. The microwave condition the
reaction is completed in short time and yield is high as compared to thermal condition.
57
Drug (Quercetin) interaction with chitosan and functionalized chitosan

in acetate buffer-DMSO medium through physicochemical properties
Reena Tondwal, Man Singh
School of Chemical Sciences, Central University of Gujarat, Gandhinagar 382030, India
The drug (quercetin) interaction with 0.015 to 0.24 g∙L-1 of chitosan (Chi) and
functionalized chitosan (f-Chi) have been analyzed by using physicochemical properties
performed at T= 298.15K and 0.1mPa. The physicochemical parameters (PCPs), viscosity
(η), density (ρ), surface tension (γ) and relative viscosity (ηr), friccohesity (σ), surface
excess concentration (Γ), surface area (Amin) illustrated stronger interaction of quercetin
with Chi and f-Chi. Hydrophilic-hydrophobic interactions to monodisperse the quercetin
with increasing carbon atom of f-Chi is predicted through these PCPs. In case of MChi
(methionine functionalized chitosan) at higher concentration (0.24 g∙L-1), the density,
viscosity, and friccohesity value increases with quercetin due to decrease in cohesive forces
and increase in intermolecular forces. The Γmax values are higher with higher
hydrophobicity and stronger binding forces which produced greater internal pressure and
lower surface area. In case of MChi with enhanced surface activities, the quercetin strongly
interact with f-Chi by decreasing cohesive forces with stronger shear due to intermolecular
forces like van der Waal forces and electrostatic interactions. The antioxidant activity of Chi
and f-Chi with and without quercetin inferred that high surface area shows high scavenging
of free radicals. The drug (quercetin) interaction with 0.015 to 0.24 g∙L-1 of chitosan (Chi)
and functionalized chitosan (f-Chi) have been analyzed by using physicochemical
properties performed at T= 298.15K and 0.1mPa. The physicochemical parameters (PCPs),
viscosity (η), density (ρ), surface tension (γ) and relative viscosity (ηr), friccohesity (σ),
surface excess concentration (Γ), surface area (Amin) illustrated stronger interaction of
quercetin with Chi and f-Chi. Hydrophilic-hydrophobic interactions to monodisperse the
quercetin with increasing carbon atom of f-Chi is predicted through these PCPs. In case of
MChi (methionine functionalized chitosan) at higher concentration (0.24 g∙L-1), the
density, viscosity, and friccohesity value increases with quercetin due to decrease in
cohesive forces and increase in intermolecular forces.
Synthesis of 2’, 6’-Dihydroxy Chalcone Using Lithium

Hydroxide as a Base
Sampat Suryawanshi, Pramod Kulkarni
Department of Chemistry, Hutatma Rajguru Mahavidyalaya, Rajgurunagar Dist-Pune
410505
Hydroxy chalcones are found medicinally important compounds. They shows various
bioactivity like anticancer, antimicrobial, anti-inflammatory and antituberculosis as well
as synthetic intermediates for synthesis of heterocyclic compounds. Due to its
importance in medicines and synthetic organic chemistry, scientists are attracted
towards the synthesis of hydroxyl chalcone. The 2’, 6’-dihydroxy chalcones are sterically
hindered compound, and the reported methods for synthesis of this compounds are
suffer from shortcomings such as low yield, long reaction time, using toxic and hazardous
catalysis etc. Here, we report the improved method for synthesis of 2’,6’—
dihydroxychalcone using lithium hydroxide as base catalyst for the condensation
reaction between 2,6-dihydroxy acetophenone and substituted benzaldehyde in ethanol
as solvent. The merit of this method is moderate to high yield, use of inexpensive catalyst
and easy workup procedure.
58
Direct N-H/N-alkyl Aziridination of Alkenes

Jawahar L. Jat
Department of Chemistry, Babasaheb Bhimrao Ambedkar University (A Central
University), Lucknow, U.P. 226025, India
Unprotected Aziridines (N-H/N-Me) are well represented in numerous bioactive

compounds, natural products and pharmaceuticals as well as being essential building
blocks in organic synthesis and drug design. Herein we describe the highly efficient
method for regio and stereospecific synthesis of aziridines (N-H/N-Me) from olefins in a
single step by using O-(sulfonyl) hydroxylamines, Rhodium as catalyst in
trifluoroethanol. This unique process installs an N-H Aziridines to simple or substituted
olefins in a single step. The substrate scope and reaction mechanism will be discussed.
Reference:
S. Sabir; C. B. Pandey; A. K. Yadav; B. Tiwari; J. L. Jat, J. Org. Chem., 2018, 83,12255.
Synthesis and spectral studies of co and ni complexes of

diacetato-bis-(p-methoxy phenyl carbonyl azomethine
benzene sulphanilamide
Garima Pandey1* , Pallavi Jain1, Swati Sharma1, Neeraj Kumar1
1 Department of
Chemistry, SRM-IST, Delhi NCR Campus, Modinagar,
Ghaziabad, 201204
A novel Schiff’s base ligand Diacetato-bis-(p-methoxy phenyl carbonyl azomethine

benzene sulphanilamide was synthesized and its configuration was determined by
performing elemental-analysis, melting point analysis and spectroscopic studies. The
complexes of Co and Ni with the synthesized ligand were then isolated and their molar
conductance and magnetic moments were determined. The conductance and magnetic-
moment studies established the electrolytic nature of these complexes. Spectroscopic
analysis of the complexes assigned the six coordinated octahedral and or tetragonal
geometry for the metal complexes.All the synthesized complexes were assessed for their
biocidal activity and based on the result of these studies it is been established that the
metal-complexes of the prepared Schiff based ligand have more inhibition-potential, than
the Schiff’s base ligand entity.
Keywords- Schiff’s base ligand, Spectroscopic analysis, Transition-metal complexes,

Biocidal activity
59
Theoretically Inspired Electro Optic Chromophores

with Substituent Changes in the first order Β Values
Tanmay Dashaputre1 Dr T Vijayakumar2*
Department of Electronics and Communication Engineering, SRM institute of Science and
Technology, Kattankulathur, Tamilnadu, INDIA, 603203
Department of Physics and Nanotechnology, SRM institute of Science and Technology,
Kattankulathur,
In recent years there has been development in the field of electro optic chromophore
which tends to exploration the field like ultrafast optical communication. The potential
material (Halogen derivative) simulated shows the immense increase in the first order
hyperpolarizability values and the other potential materials shows the certain pattern of
change in the value of hyperpolarizability.
The phenomenon such as resonance (+R) effect and inductive(-I) effect exerted by
halogen atom in para position pushes the electrons in opposite direction in long
conjugated π bonds in structure which enables the ligand to donate the electron and thus
increase in value of hyperpolarizability. Hence the halogen-based chromophore that is
TRIBRDIBAM engineered using the Gaussian 09W and the various characteristics have
been analysed using the first set of density functional theory and certain arrangements of
the atoms in this chromophore gives the enhanced value of 1st order hyperpolarizability,
dipole moment hence making it suitable candidate for ultrafast laser space
communication application.
Synthesis And Pharmacological Studies of Imidazo[1,2- a]Pyrimidine

Derivatives Of Imidazole/Triazole Clubbed Pyrazole
*Pratibha Prasad and Manish P. Patel
Department of Chemistry, Sardar Patel University, VallabhVidyanagar -388120, Gujarat, India
A new, rapid, green synthetic procedure for imidazo[1,2-a]pyrimidine derivatives

8,9(a-g) has been developed by utilizing one-pot three-component cyclocondensation
reaction protocol best accelerated by microwave in presence of ecofriendly couple
KOH/aq.EtOH solvent system. The key intermediate α, β-unsaturated ketone formed in
situ was achieved by claisen-schimdt condensation reaction of pyrazole aldehyde
clubbed with imidazole4 / triazole5 nucleus with various substituted-phenyl/hetero-
aryl-ethanone 6(a-g) followed by cyclization with 2-amino benzimidazole 7 which
efficiently tuned to afford the target compounds. This one-pot process accomplished in
two ways either in one-step or in two-step of which execution of latter methodology in
assistance of microwave afforded the targeted product in good yields.
This method had the advantages of operational
simplicity, mild reaction conditions, short reaction time,
enhanced yield with environmental impact. All the
derivatives were in vitro screened for their capability to
inhibit bacterial, fungal, malarial and tuberculosis
pathogen strains. As evident from SAR study result
revealed that some the compounds were found to be
equipotent or more potent than that of standard drugs.
60
DBU−Catalyzed Domino-Aldol-hetero-Diels−Alder Reaction in

Glycerol: Efficient Synthesis of Tricyclic Pyrano[3, 4−c]chromenes
Gaurangkumar C. Brahmbhatt,†Bhagyashri D. Parmar,†Narsidas J.
Parmar,†*Rajni Kant‡ and Vivek K. Gupta‡
†Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Anand,
Gujarat 388120, India
Domino Aldol-hetero-Diels−Alder (DAHDA) synthetic sequence was studied and

optimized in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) in glycerol at
120 °C, to achieve tricyclic pyrano[3,4-c]chromene frameworks assembling a variety of
acyclic or cyclic mono ketone compounds with prenyl ether-tethered aldehyde
substrates. Aldol-intermediates and corresponding final DAHDA products achieved in
situ from them have been characterized by 1 H and 13 C NMR spectral data. The single-
crystal X-ray diffraction data, in agreement with 2D NMR NOESY supports the cis-fusion
between the central pyran and thiopyran rings, which indicates the endo-E-syn a most
favored pathway of the final Diels-Alder reaction step.
Investigation of the kinetics of catalytic ozone reaction

using a manganese catalyst
Pragya Singh1, Snigdha Khuntia2
1Junier Research Fellow, under project code ECR/2017/001475 DST, Ahmedabad
University, Gujarat, India
2Assistant Professor, School of Engineering and Applied Science, Ahmedabad
University, Gujarat, India
Ozone is a powerful oxidizing agent which is studied for the removal of many organic
pollutants. However, some emerging pollutants, such as pesticides, pharmaceuticals
and short chain carboxylic acids, are difficult to mineralize using only ozone.
Therefore, in this work, the modified manganese catalyst has been used to alleviate the
ozonation process in the aqueous system. The study of operating parameters such as,
the effects of catalyst, pH and the radical scavengers on the degradation of a model
pollutant (e.g. Phenol) was evaluated. The contribution of hydroxyl radicals and
molecular ozone on the oxidation of phenol was studied for both homogeneous and
heterogeneous catalytic systems. The heterogeneous catalyst shows a rather complex
mechanism as compared to homogenous catalyst. In presence of manganese catalyst,
the ozone decomposition and successive generation of hydroxyl radical is faster as
compared to homogeneous catalytic system. The effect of change in pH 3-9 was not
showing any major difference in the degradation of pollutant. It was observed that, the
surface of the catalyst undergoes multiple oxidation reaction and plays the major role
in generation of the hydroxyl radicals.
A considerable amount of phenol degradation was
observed even at low catalyst dose. The rate constants
of the homogeneous and heterogeneous catalytic
reactions have been calculated and compared in this
work. In addition to that, the percentage contribution of
the molecular ozone and the hydroxyl radicals for the
degradation of the model pollutant has been evaluated.
61
Synthesis of New Pd (II) Complexes for Oxidative-

Cyclization Reactions under Visiblie-light-driven
Someshwar Pola and Suresh Kiluru
Department of Chemistry, Osmania University, Hyderabad
Metal complexes used as a photocatalyst in degradation of dyes and splitting of water

molecules in the presence of Pd (II) complexes.1 In this study, Pd(MPPT)Cl2,
Pd(DMPMPT)Cl2 and Pd(DCMPPT)Cl2 complexes are obtained by single step reaction
with MPPT/ DMPMPT/ DCMPPT and Pd(CH3CN)2Cl2 in toluene at 80oC. All the Cu-
complexes are pure and mass spectral data, and elemental analysis coincide. The thermal
behavior of the complexes characterized by thermal gravimetric analysis (TGA) and
thermograms of complexes exhibited thermal stability up to 350 oC. Therefore for this
region, no water molecules are present in either lattice or coordinated. The optical study
showed the absorption at 624 and 630 nm recognized to the d-d transitions, respectively.
Considering the well thermal stability and absorption well within the visible region,
sensibly, Cu (II) complexes have been used as a photocatalyst for the oxidative
cyclization under solar light. The repeatability and reusability study confirmed the
stability of the photocatalyst. The verification of the photocatalytic effect was also
established using rhodamine B (RhB) degradation2 under solar light. The bandgap
energies of Cu (II) complexes are suitable for nature to the generation of ●OH radicals
during the catalytic reaction. For this reason, higher oxidative cyclization 3,3'-dibromo-
5,5',6,6'-tetramethyl-1H,1'H-2,2'-biindole with aryl boronic acids in the presence of
Pd(DCMPPT) as well as a very active photocatalyst for degradation of RhB, desirable high
surface area, and low bandgap energies.
References
1. P. Someshwar, S. Mahesh, G. Ravinder, M. Vithal, Y. T. Tao, RSC Advances, 2015, 5,
58504.
2. G. Ravi, N. K. Veldurthi, S. Palla, V. Radha, P. Someshwar, M. Vithal, Photochemistry and
Photobiology, 2013, 89, 824.
62
Bidentate thiosemicarbazone and its coordination complex:

structure elucidation and biological investigation
Pallavi Jain1*, Garima Pandey1, Swati Sharma1, Neeraj Kumar1, Dinesh Kumar2,
Sulekh Chandra3
1Department of Chemistry, SRM Institute of Science & Technology, Modinagar, Ghaziabad,
201204, India; 2School of Chemical Sciences, Central University of Gujarat, Gandhinagar,
382030, India; 3Department of Chemistry, Zakir Hussain Delhi College, JLN Marg, New Delhi-
110002, India
In today’s scenario, the discovery of various fungicidal and bactericidal drugs has become
essential because of enhanced microbiological and clinical resistance of microbes. So,
keeping this in mind, some novel Cu(II) complexes of bidentate ligand were synthesized
which operate as antimicrobial agent. The bidentate ligand is synthesized after
condensation reaction of 1 mole of phenylcarbamate and 1 mole of thiosemicarbazide in
ethanolic medium.The ratio of metal salt to multi donor atom containing ligand was 1:2.
The conventional condensation metod was employed to synthesize metal complexes. The
different techniques such as melting point, elemental analysis, 1H-NMR, mass, electronic
spectra, molar conductance, magnetic moment, infra-red, UV-visible, electron
paramagnetic resonance and molecular modeling study were utilized for structural
elucidation and for characterization of the ligand and its complexes. Well diffusion
method was carried out for biological investigation of all the synthesized compounds at
different concentration against different pathogenic fungi C.Krusei, C. Parapsilosis and
bacteria E. coli and S. aureus. The experimental results shows enhanced inhibition zone
than free bidentate ligand, which confirms that after complexation the biological activity
enhances.
Keywords: Thiosemicarbazide, metal complexes, spectroscopic, molecular modeling,
antimicrobial study
Engineered multifunctional nanoconjugates for photothermal

therapy and multi drug delivery
Manita Das, Sonal Thakore
Department of Chemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda,
Vadodara 390 002, India
Photothermal therapy is one of the many approaches towards targeted delivery of

anticancer agents. Carbon nanotubes (CNTs) are useful for this purpose because they
have high photothermal efficiency. They can be conjugated to stimuli responsive
polymers for light induced delivery at target sites. Fluorescent tagged multifunctional
nanoconjugates were successfully synthesized based on carbon nanotubes (CNTs) and
characterized by several analytical techniques. The nanoconjugates exhibited heating
effect with Near IR irradiation as well as thermoresponsive drug release. Further, the
nanocarriers were also designed to carry hydrophobic anticancer agent (Curcumin) as
well as hydrophilic drug (Doxorubicin hydrochloride) simultaneously. Cancer cell
targeting ligand folic acid facilitates accumulation and internalization of the
nanocarriers in and around tumor cells in preference to healthy cells. The results show
that superlative release of DOX could be obtained under acidic pH conditions and
elevated temperature, which coincides with the tumor microenvironmen.
63
Liquid-liquid demixing of aqueous solution of ionic liquids in

presence of inorganic salts: Phase diagram and application
Sushma Ijardar
Department of Chemistry, Veer Narmad South Gujarat University, Surat, Gujarat.
Liquid-liquid extraction (LLE) systems are most widely studied separationand

purification technologies. The efficacy of extraction/purification technology depends
on higher selectivity, lower energy inputsfor attaining equilibrium, retaining chemical
structure,activity and stability of biomolecules. Typical LLE systems, organic
compounds exhibit high volatility, substantial levels oftoxicity and thus poor
biocompatibility leading to denaturation of bioactivecompounds like
proteins.Therefore, a need to replace traditionalLLE with more biocompatible and eco-
friendly systems was consideredvery essential. Ionic liquids possess bunch of unique
properties apart from them negligible vapour pressure at room temperature and non-
flammability makes them suitable in replacement of VOC in industries. An aqueous
solution of ionic liquid has been used with inorganic salt to create aqueous biphasic
systems (ABS). Well defined phase diagrams withsuitable tie-lineswere obtained by
cloud point method at 303 K.The nature of inorganic salt to induce phase separation
will be discussed. ABS will be demonstrated for portioning of biomolecules.
Plasmonic Response of Anisotropic Gold Nanostructures

Dr Abhitosh Kedia
Department of Physics, Uka Tarsadia University
The resonant electromagnetic behavior of noble-metal nanostructures, giving rise to
localized surface plasmon resonances (LSPRs) in nanoparticles due to the confinement
of conduction electrons in a much smaller particle volume, further producing a strong
resonantly enhanced homogeneous near field in the immediate vicinity of the particle
surface, from which most of the promising applications (such as SERS, sensing etc.) of
metal nanoparticles stem out. With the advent of numerous chemical and physical
methods for the synthesis of size/shape controlled metal nanostructures, there is a
constantly growing need for both experimental and theoretical investigations for better
understanding the nature of LSPs that occur at the geometrically bounded surface of
metal nanoparticles as well as their interaction with light.
Herein, we engineer the plasmonic response of 3D complex shaped gold nanostars over
the entire visible/NIR spectral range based on the anisotropic etching process using
foreign agent in at room temperature in just one step process, which fine tunes the
corresponding LSPs. Their intuitively modified plasmonic characteristics were analyzed
through electron microscopy and detailed spectroscopic measurements. Furthermore
the spectroscopic results of these anisotropic nanostructures are effectively mapped
with SEM-CL measurements (individual plasmon mapping) in visually displaying the
significant electric field enhancement and consequently an improved sensitivity in both
LSPR of anisotropic metal nanostructures thus allowing them to serve as excellent
substrates for wavelength-tunable surface enhanced Raman spectroscopy.
Catholuminiscence signifying the direct visualization of plasmonic eigenmodes and
their intriguing hybridization mechanism in such complex size/shaped gold
nanostructures. Experimentally obtained results were compared with the numerically
simulated data which expand insight into their interpretation and physical meaning.
64

Bioprospecting and molecular characterization of laccase producing
bacteria from industrial contaminated sites
Hiren Patel1,2*, Pooja Sharma2 and Rishee K. Kalaria3
1 .School of
Sciences, P. P. Savani University, Surat-394125
2.Bhagwan Mahavir College of Science & Technology, VNSGU, Surat-395007
3 .Aspee Shakilam Biotechnology Institutes,Navsari Agricultural university, Athwa
Farm, Surat-39500
Laccases have vast prospective for biotechnological applications due to their outstanding
bioremediation potential. These include abundant applications in effluent detoxification,
enzymatic conversion of chemical intermediates, wine clarification degradation of textile
dyes, biosensors and organic synthesis,herbicide and insecticide degradation, where
enzymatic catalysis could offer as a more environmentally alternative than the presently
used chemical processes. In the present study, two potential microbes were isolated on
solid medium containing guaiacol and ABTS for laccase activity out of 10 microbes. Two
cultures PHP7 and PKD5 were selected for further investigation. Molecular
characterization was carried out using 16S rRNA gene technology of PHP7 revealed as
Bacillus cereus (KU878970.1).Partial amplification of laccase gene contain conserved
domain of multicopper oxidase family. Further research work can be performed on these
isolates PHP7 and PKD5 by upscale the production of laccase in command to meet the
difficulty of the necessity for higher enzyme titer for the bioremediation of textile dyes.
KEYWORD:2, 2-azino-bis (3- ethylbenzthiazoline-6-sulphonic acid (ABTS); Bushnell

Haans medium (BHM); Guaiacol; Laccase;Ribosomal Deoxyribonucleic acid (rDNA).
Synthesis and Characterization of Triazolopyridine and Pyrrolo

Quinoxaline Based Bipolar Host Materials for Phosphorescent
Organic light Emitting Diodes (PhOLEDs)
Bhausaheb N. Patil, Jatin J. Lade, Kamlesh S. Vadagaonkar, Prabhakar Chetti, and
Atul C. Chaskar*
National National Centre for Nanosciences and Nanotechnology, University of Mumbai.;
Department of Dyestuff Technology, Institute of Chemical Technology, Matunga(E),
Mumbai; Nathalal Parekh Marg, Matunga (East), Mumbai-400019
New bipolar host materials comprising hole-transporting triphenylamine as well as

carbazole electron-transporting triazolopyridine and pyrrolo quinoxaline has been
synthesized, characterized and studied for phosphorescent OLED’s. Their thermal,
photo physical and electrochemical properties have also been studied.
These bipolar host materials showed
suitable frontier molecular orbital
(FMO) energy levels and ensure
excellent thermal and morphological
stabilities. These designed structures
efficiently suppress the intramolecular
charge transfer between donor and
acceptor and resulted in moderate
triplet energies (ET = 2.51-2.55 eV).
65
Experimental and Theoretical Approach of TTA Antenna based

Tunable Light Emissive Eu(III) Complexes for Versatile applications
Rajamouli Boddula
Department of Chemistry, Uka Tarsadia University, Bardoli, Surat, Gujarat, India
Organometallic complexes are have significant attention asthe emission mechanism in

molecules used in organic light-emitting diodes(OLEDs). Design and application role of
the luminescent molecular materials are an attractive research trend in recent direction
for reducing the energy crisis in the field of the lighting applications such as full-colour
panel displays (OLEDs) and solid state lightings (SSL, including white LEDs) [1]. Research
on highly emissive red and blue phosphors for warm white LEDs and smart full-colour
displays are highly imperative. To achieve the same a great deal of effort has been
devoted to syntheses of Ln complexes due to their unique optical properties (a line like
(4f-4f) emission spectrum and capable emitting different spectral windows). Among all
Ln complexes, red-emitting phosphorescent emitters (Eu(III) complexes) are efficient
and widely used in OLEDs and LEDs.In general, the Eu(III) complex showed red emission
and producing a white emission is a challenging research task. However, the design
strategy followed to balance the primary colours (Blue, Green and Red) and it results in
white light emission from the complex [2].
In the present study, a new class of bipolar phenanthroimidazole based (N1
functionalization with Ph, mCF3, pCF3 and Fl) ligands and their efficient -diketonate
Eu(III) complexes have been designed, synthesized, characterized successfully and their
photophysical, electrochemical properties have also been investigated. All the ligands
and complexes show similar UV-Visible absorption behaviour (~270, ~360 nm).
Photoluminescence emission spectra of Eu-complexes and its ligands were carried out in
solution form as well as in the solid and thin film. The PL study indicates that the Eu-
complex emits tunable emission due to incomplete/partial energy transfer (white
(solution), red (solid)), whereas fluorene-based Eu-complex shows narrow band red
emission with appropriate CIE colour gamut. The energy transfer mechanism was
proposed based on combined experimental and theoretical study (DFT, TD-DFT). The J–O
intensity parameters, electrochemical study and absolute QY (mCF3 based Eu-complex-
better QY of 75.9%) of the complexes were also been investigated. White and red LED
was fabricated using these complexes with near UV LEDs (395 nm). The detailed
investigation will be presented and discussed.
HIGHLIGHTS: Photoluminescence, LEDs and white emission.
REFERENCES
[1] Guangjie He, Dong Guo, Cheng He, Xiaolin Zhang, Xiuwen Zhao, ChunyingDuan,
Angew. Chem. Int. Ed. 2009, 48, 6132 –6135.
[2] B. Rajamouli, S. Kasturi, S. Giri and V. Sivakumar, Inorg. Chem., 2017, 56, 10127–
10130.
66
Ru-catalyzed unusual benzylic oxidation of Dodecahydrotriphenylene

Gaurang J Bhatt, Pradeep T Deota*
Applied Chemistry Department, Faculty of Technology & Engineering, M.S. University
of Baroda, Vadodara
Trindane (1) and its higher homologue Dodecahydrotriphenylene (DDHTP) (2) have
attracted attention for construction of higher polycyclic hydrocarbons. Oxidation of
trindane using RuCl3/NaIO4 was reported by S. Ranganathan, where oxidation takes
place in benzene ring of trindane to give a highly oxygenated product (3) [1]. Here we
report our results on similar oxidation of DDHTP wherein only benzylic oxidation takes
place giving keto products (5) and (6) instead of the expected ring cleavage product (4).
Mixture of decahydrotriphenylene-1-one (5) and octahydrotriphenylene-1,5-dione (6)
were isolated and characterized. It is reported that DDHTP gives only (5) in the presence
of CrO3 . To the best of our knowledge (6) is not reported. The chemistry of this reaction
will be discussed.
1. Subramania Ranganathan, K. M. Muraleedharan, Chem. Commun., 1998, 2239.
Synthesis and characterisation of gold nanoparticles and their

bioconjugates with bovine serum albumin and flavonoids
K.M. Sachin and Man Singh*
School of Chemical Sciences, Central University of Gujarat, Sector-30,
Gandhinagar- 382030, India
The higher surface areas of the Gold nanoparticle (AuNPs) could induce the activities in
the proteins molecules, and their interfacial linkages could be very dynamic in
engineering the biochemical activities. Similarly, the globular protein and flavonoids have
been the most effective biomolecule as an effective networking with AuNPs to develop
functional nanobioconjugates with higher biological potentials in engineering. Thus, the
AuNPs-BSA and AuNPs-Fv conjugates could offer distinct physical and chemical activities
and acts as excellent scaffolds for employing them as carrier systems. In general, the
AuNPs-BSA and AuNPs-Fv conjugates holds great potential for biomedical applications in
sensing, diagnostic, therapeutic delivery control of protein activity and in imaging
applications. We are synthesised AuNPs and functionalised with BSA and flavonoids and
their AuNP-bioconjugates confirmed by using UV-vis spectroscopy, TEM, DLS, FTIR, TGD-
TA and DSC analysis.
67
Synthesis and optical response to acids and bases of a new

Styrylddihydro-benzo[a]phenazine chromophores
Sharad Patil*
Chemistry, Department of Chemistry, UkaTarsadia University, Bardoli – 394
350, Gujarat, India
Four novel styrylddihydrobenzo[a]phenazine chromophores have been synthesized and

spectroscopically characterized. They respond to acids and bases through changes in
absorption resulting in strong bathochromic shift (>437 nm). The emission quantum
yields of the dyes were in the range 0.11-0.14. Computational studies have been
performed to provide further insights into the nature of electronic transitions for the
synthesized dyes. The qualitative trends observed in the optical properties,
halochromism and geometrical isomers were supported by density functional theory
(DFT) computations.
Study about Bis-Chalcone based Photoluminescence Lanthanide

Metal Complexes as Photodynamic Drug Carrier
Paresh N Patel*
Highly conjugated photo responsive complexes of Eu(III), Tb(III) and Gd(III) with bis-
chalconeligands were synthesized andcharacterized by IR, 1H NMR, 1H-1H COSY, 13C
NMR, mass spectral analyses, single crystal XRD data and thermo gravimetric analysis.
The lanthanide complexes of prepared ligands are more flexible than other tridentate
ligands [1], and have several synthetic and structural advantages over other lanthanide
complexes. These complexes have not been investigated systematically for their PDC. In
this study, automated docking was used to determine the orientation of the synthesised
molecules that response to few radiations. These initial results will be presented during
the conference.
References:
1. S Rai, PN Patel, AChadha. Crystallography Reports2016, 61/7, 1086.
68
Abstract for Poster Presentation

69
Antioxidant activity of hydroalcoholic extract and cardiac glycoside

fraction of calotropis spp. With-respect-to lunar cycle
KEJAL GOHIL1 , ASHOK SHAH2
1- C.G.B.I.BT, Uka Tarsadia University, maliba campus, Bardoli, 394350,Gujarat,India
2- Propioretor of Prasad biotech,Gundlav chokdi, valsad,396001
From ancient time to modern era, Calotropis procera (LINN.) and Calotropis gigantea
(L.) R BR. (asclepediaceae) both spp. are used for welfare of human being, either in a
spiritual or in a medicinal use as they contain many bioactive principles mainly cardiac
glycoside. However, Ayurvedic and Indian medicinal system have recommended to
collecting the parts of calotropis spp. on the day after amavasya (new moon) and
purnima (full moon) in three seasons in order to get optimum phytoconstitute and
effective therapeutic index without extra exploitation of medicinal plant resource from
planet. Calotropis spp. are used to treat the disease like anti diabetic, cold, eczema,
rheumatism, anticancer, anti-inflammatory etc. Overproduction of free redicals and
oxygen reactive spp. leads to many pathological condition. So in this investigation,
highest cardiac glycoside content from the full moon and new moon was extracted with
alcohol: ethanol (1:1). Crude extract further extracted and hydrolysed which gives a
cardiac glycoside rich fraction and then antioxidatively quantified it. The highest Cardiac
glycoside content was observed in summer in new moon (432.83±1.03mg/g) and lowest
was in monsoon in full moon. The free radical scavenging activity of both the plant
extract was evaluated with DPPH activity, cuprac assay, and FRAP assay and significantly
correlate with total phenolic content. An effectiveness of radical scavenging activity of
whole plant extract and pure compound were greater than standard ascorbic acid.
The effects of small molecule mediated G-Quadruplex

stabilization on induction of Autophagy
Piyali Majumder1 and Bhaskar Dattta 1*
1 Biologcal Engineering Discipline, Indian Institute of Technology
Gandhinagar, Palaj, 382355
Autophagy is a housekeeping cellular homeostatic mechanism, whereby cells

auto-digest proteins, lipids and organelles of their cytoplasm for removal or
turnover.Due to their biological significance, G4 structures have emerged as
possible target for therapeutic intervention in human diseases.Recently, an
anthracene based drug was reported to induce autophagy in melanoma cells. This
anthracene based drug is believed to initiate the autophagy by G4-stabilization
activity.Our group has developed certain carbocyanin based drugs that exhibit G4
selective binding. In this study, carbocyanine ligands effect on autophagic pathway
was monitored via the MTOR gene regulation. The GQRS mapper tool revealed
that the MTOR gene has 46 potential G4 forming rich sequences. Moreover, mTOR
being the key negative regulator of autophagy, G4 ligand treatment
downregulated the mTORactivity that leads to the induction of excessive
autophagy. Thus this study unraveled that carbocyanine based G4 ligands have a
unique property to induce autophagy through G4 stabilization.
70
Synthesis and characterization of bisazo reactive dyes and their

applicaion on various fibres
Alkesh B. Pate1, Divyesh R. Patela and Paresh S. Patel
Department of Chemistry, Veer Narmad South Gujarat University, Surat-395007.
a. M.R. Arts and Science College, Rajpipla, Gujarat
Various bisazo reactive dyes have been synthesized by coupling of tetrazotized
4,4’-methylene bis(2,5-dimethylaniline) with various 4-β-sulphatoethyl
sulphonylphenyl-1-amino cyanurated coupling components such as H-acid, J-acid, N-
methyl J-acid, N-phenyl J-acid, N-benzoyl J-acid, Gamma acid, Peri acid, Bronner acid,
Laurent acid, K-acid, S-acid, Tobias acid, Cleave acid and Koch acid. They were
characterized by nitrogen elemental analysis, IR and 1 HNMR spectra. The dyeing
performance of all these dyes on silk, wool and cotton fibres showed fair to very good
light fastness, good to excellent fastness to wash and rubbing fastness.
Solubility and thermal study of polyesters containing

coumarin ring in the main chain
Kamlesh D. Prajapatia Pramod M. Gamitb & Vidhya V. Patelb
a Department of chemistry, V. S. Patel arts & science college, Bilimora-396321,
Gujarat, India; b Department of chemistry, Uka Tarsadia University, Bardoli-394350,
Gujarat, India.
Polyesters containing coumarin ring in the main chain were synthesized by high
temperature polycondensation reaction using cetrimide as an initiator. The
synthesized polyesters were characterized by various techniques like FTIR, NMR and
fluorescence. The inherent and reduced viscosities were checked by ubbelohde
solution viscometer. The relative solubility of these polyesters were determine in a
variety of solvents. Thermal stability was studied by TGA and DTA techniques. The
obtained polyesters possess high thermal stability with good solubility in common
organic solvents.
Computer colour matching data of some newly

synthesized bifunctional reactive dyes
Jigna A. Patela and Paresh S.Patel
Department of Chemistry, Veer Narmad South Gujarat University, Surat-395007.
A series of bifunctional reactive dyes has been synthesized by coupling of diazotized 3-

{4’-[4’’-amino-2”-sulphatobenzyl]-3’-sulphatophenyl}-2-methyl-quinolin-4(H)-one
with various 4-β-sulphatoethylsulphonylphenyl-1-amino cyanurated coupling
components such as H-acid, Gamma acid, J-acid, N-Methyl J-acid, N-Phenyl J-
acid, Chicago acid, S-acid, K-acid, Bronner acid, Peri acid, Laurent acid and Koch acid.
They were characterized by nitrogen elemental analysis, IR and 1 HNMR spectra. The
dyeing performance of all these dyes on wool, silk and cotton has also been assessed.
Spectral properties and colorimetric data (L*, a*, b*, C*, H* and K/S) have also been
investigated
71
Physical properties of polymeric materials containing

heterocyclic ring in backbone
Pramod J. Patila, Pragnesh C. Patelb & Divya S. Vanib
Department of Chemistry, Uka Tarsadiya University, Bardoli, Surat, Gujarat-394350
Polymeric materials containing heterocyclic ring in the main chain were synthesized
by high temperature polycondensation reaction of substituted s-triazine and different
diols. All polymers were obtained in good yield and were characterized by solubility,
viscosity measurement, FTIR and NMR spectral analysis. Thermal stability was studied
by TGA technique. The synthesized polyester showed good thermal stability along with
good solubility in common organic solvent.
Microwave assisted extraction of silicon from bagasse fly ash for

the synthesis of MCM-41 and application for cadmium removal
Alpesh V. Patel
Seth P. T. Mahila College of Arts and Home Science, Surat, Gujarat, India
This study reports the extraction of silicone present in the bagasse fly ash (BFA) which
is primary building block of MCM-41(Mobil Composition of matter no. 41). The
extraction was performed by conventional alkali reflux technique and combine this
with microwave irradiation method. The combined method found best for the
extraction of the silicone form BFA. The MCM-41 was synthesized from the extracted
silicone and Cetyl trimethyl ammonium bromide (CTAB) as a structure-directing agent.
The obtained product was characterized by the advance analytical techniques such
small angle X-ray diffraction (SAXRD), X-Ray florescence (XRF) scanning electron
microscopy (SEM), transmission electron microscopy (TEM), Fourier transform
infrared spectroscopy (FTIR), and nitrogen absorption–desorption measurement
(BET-BJH). It was confirmed that the synthesized material exhibited a well-ordered
mesostructure with high surface area, large pore volume and pore diameter in
nanometre range. The removal efficiency towards cadmium ion was performed
through synthesized MCM-41 at optimized sorption condition. Therefore, the material
could be potentially used as a low-cost and efficient adsorbent candidate to treat
cationic metal contaminant from industrial waste water.
Synthesis Of Nano-Hydroxyapatite from Waste Egg Shells for

the Controlled Release of Urea
Mrs.Meghana Panchal, Jalpesh Kucha, Harishchandra Jirimali
Department of Chemistry, Uka Tarsadia University, Bardoli, Gujarat 394350 India
Nanostructured Hydroxyapatite (HAP) is the biomaterial getting its important due to

its higher surface area and biocompatibility. In the present work, HAP is synthesised
from the waste egg shells as a source of calcium. The urea-HAP composite was
prepared by simple agitation at room temperature. The structure of the synthesised
HAP was conformed by Powder XRD and FT-IR. The nanostructured and the surface
morphology of the synthesised HAP was observed by the SEM. The controlled release
of the prepared Urea-HAP was performed in the closed chamber with the continuous
flow of water. The obtained results showed the better retention of urea in the Urea-
HAP as compared to the Urea.
72
Synthesis Of Nano-Hydroxyapatite from Sea Shells for the

Controlled Release of Urea
Shreya H Patel, Mrs.Meghana Panchal, Harishchandra Jirimali
Department of Chemistry, Uka Tarsadia University, Maliba Campus, Gopal Vidya
Nagar, Surat Gujarat 394350 India
A nanotechnology-based principle for delivering nutrients to crops is getting important

in developing countries, thus, it is important to develop technologies that minimize the
cost of fertilizers through efficient and targeted delivery. In this study, the high solubility
of urea molecules has been reduced by incorporating it into a matrix of hydroxyapatite
nanoparticles. hydroxyapatite nanoparticles have been selected due to their excellent
biocompatibility while acting as a rich phosphorus source. In addition, the high surface
area offered by nanoparticles allows binding of a large amount of urea molecules. HAP
was synthesized from the seashells by the ultrasonic method and urea composite was
prepared insitu and step by step methods. The method is simple and scalable, allowing
the synthesis of urea-modified hydroxyapatite nanohybrid as fertilizer having a ratio of
urea to hydroxyapatite of 6:1 by weight. Specifically, a nanohybrid suspension was
synthesized by in situ coating of hydroxyapatite with urea at the nanoscale.
Treatability Study ofSugar Mill Effluent byGreen Oxidants:Ferrate

Harsh Prajapati* and Ravi Amipara
Institute of Research and Development, Gujarat Forensic Sciences
University, Gandhinagar
Treatability study are carried out to identify suitable coagulant and its dosage, for
primary treatment of effluent with aim to remove suspended solids and reduction in COD
before biological treatment. Conventionally, alum, lime, PAC, Polyelectrolytes are
commonly used as coagulant. In this study, the use of greener oxidantFerrate for
treatability study of sugar mill effluentis explored. Ferrate is referred to a supercharged
iron molecule in which iron is in the plus six oxidation state and is also commonly known
as Iron (VI). Contemporarily, Ferrate is under intense study by the scientist due to its
potential to replace alum, polymers and ferric chloride in removal of metals, nonmetals,
organic components, color, odor and natural organic materials (NOM). A single
application of ferrate has the ability to work as an oxidant, coagulant and disinfectant. In
this study, we have synthesized ferrate by wet chemical method, explored it for the
treatment of sugar mill effluent and treatment efficiency is calculated. The effluent also
given primary treatment with conventional method using alum and subsumed the
comparison study. The obtained results clearly indicates preeminence of Ferrate in
comparison to conventional treatment with alum and its potential to be used as
alternative in primary treatment of sugar mill effluent.
Key Words: Treatability study, Sugar Mill Effluent, GreenOxidant, Ferrate

73
Cavitation approach for Wastewater treatment

Kunj S. Talati, Amrutlal L. Prajapat*
Department of Chemistry,UKA Tarsadia University , Bardoli.
Waste water generated by pesticide and chemical industries is certainly a serious matter with
reference to Indian context. Wastewater contains toxic and non-biodegradable compounds.
Existing wastewater treatment methods: adsorption on activated carbon, extraction, and
chemical oxidation. Limitations of existing methods: limited applicability and low efficiency.
The need of research into alternative treatment techniques. Cavitation has the potential to
degrade the complex chemicals like pesticides with the help of higher temperature, high
pressures, high kinetic energy and radicals generated by it. A promising way to achieve the
degradation is by combination of cavitation with advanced oxidation processes (AOPs)
based on production of hydroxyl radicals under mild experimental conditions.
A Green protocol for the synthesis of some pyrazoline derivatives

using microwave technique
Swami Poonam1 *, Disha Chaudhary2 , Akshay Kodiyawala3 and Bhavin R.
Patel4 , Jignesh P. Raval5
Department of Chemistry, Uka Tarsadia University, Bardoli-Mahuva Road, Tarsadi-
394 350, Gujarat, INDIA, 5Mandvi Education Society (TMES), Mandvi, Dist: Surat,
Gujarat, INDIA
Nitrogen, sulfur and oxygen containing small heterocycles have been under investigation for a
long time because of their important medicinal properties. It was known that 2-pyrazolines
possess a variety of significant and diverse pharmacological activities. So, in light of these
findings, we report the synthesis of some 3-substituted phenyl-5-substituted phenyl-4,5-
dihydro-pyrazole-1-carbothioamides using microwave technique. In the present approach,
substituted acetophenones were reacted with appropriately substituted benzaldehydes in the
presence of ethanol to furnish substituted chalcones. Reaction of these chalcones with
thiosemicarbazide yielded substituted 3,5-diphenyl-4,5-dihydro-1H-pyrazole-1-
carbothioamides. The structures of newly synthesized compounds and have been confirmed
by suitable spectroscopic techniques such as IR and 1 H NMR.
Extraction Of Natural Dye From Rose Flower Using Ultrasound

Raiyan Kapadiya, Amrutlal L. Prajapat*
Department of Chemistry, Uka Tarsadia University, Maliba Campus, Bardoli -
394350, Gujarat
Rose flower have been widely used as raw material in food, cosmetic and pharmaceutical
industry and contain many bioactive compounds. In this study, extraction of natural dye
from rose flower using ultrasound has been done. Several experimental parameters, such as
temperature, contact time, effect of pH, loading of material and volume of solvent has been
studied. It has been observed that the color changes from wine red (pH 4.3) to light yellow
(pH 10.0). UV-VIS spectrophotometry was used to check the % extraction of dye. The result
indicate the extraction efficiency of the colorant obtain from rose flower due to use of
ultrasound is higher as compared to the conventional extraction of dye from rose flower. It
has been also observed that there were no any changes in the quality of rose petals. So this
raw material can be used further for other food applications.
74
Antimicrobial synergy between silver and platinum nanoparticles

synthesized by Dioscorea bulbifera
Bansi Ranpariya 1 and Sougata Ghosh 1 *

1Department of Microbiology, School of Science, RK University, Kasturbadham,
Rajkot – 360020, India
Fabrication of nanoparticles with well defined size and shape is challenging for green
synthesis using plant extracts. Bimetallic nanoparticles are considered to be more active
compared to individual nanoparticles. Hereby, we have employed Dioscorea bulbifera
tuber extract for synthesis of silver and platinum nanoparticles. Further bimetallic
nanoparticles comprised of both silver and platinum was also synthesized which was
completed within 5 h at 100 °C. Bioreduced AgNPs, PtNPs and Ag-PtNPs were
characterized using UV-visible spectrophotometry, dynamic light scattering, zeta
potential measurements, high resolution transmission electron microscopy and fourier
transform infrared spectrometry. Synthesized AgNPs, PtNPs and Ag-PtNPs exhibited
superior antimicrobial activity against test organisms like Escherichia coli, Pseudomonas
aeruginosa, Bacillus subtilis and Staphylococcus aureus. Antibiofilm activity was also
evaluated for all of the synthesized nanoparticles. The present study rationalizes the use
of bimetallic Ag-PtNPs as novel antimicrobial agents.
Poly (d, l- lactide)-gentamicin composite coated orthopaedic

metallic implant
1 Mahendra Lakdawala, 1 Dhwani y. Patel & 2 Malik, G. M.
1M.L.Parmar Science College, Masma 2 Navyug Science College
Antibiotic prophylaxis is a routine procedure in orthopedic surgery. Various local

antibiotic delivery techniques are used to reduce bone and soft tissue-related infection.
The main objective of this study was to develop a prolonged gentamicin delivery system,
which can sustain the drug for at least one month, using a biodegradable polymer, Poly
(D,L- Lactide) coating on metallic implants. We investigated the release kinetics and
antibacterial properties of gentamicin impregnated Poly (D, L- Lactide) coating. In the
present study, two successive layers of drug-polymer composite were coated on SS 316 L
strip using air suspension spray coating technique to achieve a drug loading of 25 mg
/cm2. In-vitro elution of gentamicin at regular intervals, for about 42 days, from strip
was analyzed using high performance liquid chromatography (HPLC). It was observed
that the drug was continuously released over a period of one month owing to swollen
polymeric matrix and bulk erosion. Scanning electron microscopy (SEM) images indicate
smooth and crack free coating on implant surface.
KEY WORDS: Gentamicin, Poly (D, L- Lactide), HPLC, SEM
75
Phenazines and Thiazine: Green Synthesis, Photophysical

Properties and Dichroic Behavior in Nematic Host
*Dr Sharad Patil, Karan S. Patel ,Triguna P Patel and Dhruvkumar G Dhimmar
Department of Chemistry, UkaTarsadia University, Bardoli – 394 350, Gujarat, India
An efficient, mild and environmental friendly protocol is Develop for synthesis of

Phenazines and Thiazine from laws one under ultrasound irradiation in an aqueous
media. Short reaction time, ambient mild reaction conditions, simple work up and high
yield are the striking features of the present protocol. The photo physical properties of
the synthesized Phenazines and Thiazine are evaluated. Density functional theory (DFT)
and time dependent density functional theory (TDDFT) computations. The functional
used is B3LYP and the basis set 6-31G(d) is used for all the atoms. There is a close
agreement between the experimentally observe absorption-emission values and the
compute vertical excitation and emission values. The Dichroic ratio and order parameter
of the dye in nematic liquid crystal (LC) host is calculate. The Anthraquinone fused
Phenazine system is find to exhibit dichroism due to varying absorption under the
electric vectors of incident light, polarized parallel and perpendicular with respect to the
LC director.
Medicinally important silver and gold

nanoparticles synthesized by Gloriosa superba
Kaushik Kakadiya, Nikunj Khunt, and Sougata Ghosh*
1Department of Microbiology, School of Science, RK University,
Kasturbadham,
Rajkot – 360020, India
Diverse phytochemistry of medicinal plants serves as plethora of bioactive principles
that simultaneously reduce the metal ions to nanostructures as well as stabilize them.
Emerging multidrug resistance among microbes at an alarming rate has pointed the
development of novel antimicrobial agents. Similarly, the global increase in the cancer
cases has reflected the need to design new anticancer entities. Hereby, we have employed
Gloriosa superba tuber extract for synthesis of silver and gold nanoparticles, which
completed within 5 h. Optimization studies revealed that 3 mM of AgNO3 and 4 mM
HAuCl4 were optimum for maximum synthesis of AgNPs and AuNPs respectively, at 50
°C. High resolution transmission electron microscopy exhibited smaller and spherical
AgNPs at a range of 3 to 20 nm. Exotic shapes of AuNPs like spheres, triangles and
hexagons varied from 20 to 120 nm. Energy dispersive spectroscopy and X-ray
diffraction spectroscopy confirmed the elemental composition of AgNPs and AuNPs.
Fourier transform infrared spectroscopy showed broad peak from 3300 to 3500 cm-1
attributed to O-H group of phenols/alcohol, which could play a critical role in synthesis
and stabilization. Further, biochemical analysis showed the presence of phenolics, starch,
reducing sugars, ascorbic acid and citric acid. Similarly, gas chromatography-mass
spectroscopy indicated that the most predominant compounds found in GSTE, were
phenol, 3-methoxy- (C7 H8 O2 ), salicyl alcohol (C7 H8 O2 ), benzoic acid, 2-hydroxy-6-
methoxy- (C8 H8 O4 ) and asarone (C12 H16 O3 ). AgNPs exhibited superior antimicrobial
activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and
Staphylococcus aureus. Further, AgNPs and AuNPs exhibited 42.04 ± 1.87 % and 35.59 ±
4.1 % antiproliferative activity against MCF-7 cell line (human breast adenocarcinoma
cells) which was further confirmed using flow cytometry and confocal microscopy.
76
Synthesis and characterization of Nickel Sulfide Nano crystalline

Material and thin films
Komal Parmar, Jaymin Ray*, Kinjal Patel
Department of Physics, Uka Tarsadia University, Maliba Campus, Bardoli
Nickel Sulfide (NiS) is an inorganic semiconductor compound, mainly used in the field of
super-capacitors and fuel cells as an electrode. In the present study, NiS nano-crystalline
powder and thin film were prepared by using chemical method. Nickel Acetate used as a
Nickel source. For the Sulphur source we have used four source viz. Thiourea, Sodium
Sulfide ,Thioacetamide and Sodium Thiosulfate. NiS powder was prepared using solid
state method and Thin films were prepared using dip coating method. The prepared
powder and thin films were heated at 200 oC. The structural properties of the prepared
material and films were studied using X-ray Diffraction method. The optical properties
were studied using UV-Visible spectroscopy. The energy band gap and the broad (hkl)
peak indicated the prepared material is nano-crystalline.
Synthesis and Characterization of Hydroxyapatite Nano-particles

via Hydrothermal Technique
K.J. Joshi, N.M. Shah
Department of Physics, Shri J.S. Bhakta and Shri K.M. Bhakta Arts, Shri A.N. Shah
Science and Shri N.F. Shah Commerce College, Kamrej Char rasta, Surat ,PIN-394185
Hydroxyapatite( Ca10(PO4)6(OH)2) (HA) is the main inorganic compound of human

bone and teeth. Due to its similarity to bone apatite and excellent biocompatibility, it is
extensively used in biomedical field but it has also applications in non-biomedical fields
as catalyser, fertilizer, protein adsorber, etc.
In the present study, an attempt was made to synthesise Hydroxyapatite Nano-
particles via Hydrothermal technique in acidic medium. Calcium nitrate tetra hydrate
(Ca(NO3)2.4H2O) and Potassium Phosphate (K2HPO4) were used as precursors.
Potassium hydroxide (KOH) was used to maintain pH at 4.0. Hydrothermal treatment
was given to the resultant solution at 160° C for 24 h. Synthesized samples were
characterized using X-Ray Diffraction(XRD) analysis and Scanning Electron
Microscopy(SEM).Analysis of XRD data shows that peak positions are in good agreement
with standard data (JCPDS card No.-09-0432).However secondary phases such as
Calcium Hydrogen Phosphate and Calcium Carbonates are also present(JCPDS Card No.-
71-1759 and 72-16512) due to the fact that reaction was carried out in air atmosphere.
Estimated crystallite size using Scherrer’s formula is nearly 40-70 nm.SEM micrograph of
prepared samples shows 2D plate like structure which is similar to bone apatite
.Agglomeration of particles can be seen with higher magnification.
Key words- Hydroxyapatite (HA), Hydrothermal technique, X-Ray Diffraction(XRD)

analysis, Scanning Electron Microscopy(SEM).
77
Performance Improvement of Automobile Radiator by Use

of Nano-fluid - A Critical Review
Krunal Parmar
Research Scholar
In recent time automobile radiator uses water and ethylene glycol as a coolant. These
coolant offers low thermal conductivity. However to improve the thermal performance of
the system automobile radiator is carried out with the coolant which have higher
thermal conductivity. Nano-fluid have capability to increase the thermal performance of
automobile radiator used as coolant. This study aims to evaluate the performance of the
heat transfer characteristic of different Nano-fluid as coolant. The performance of heat
transfer characteristic were evaluated based on certain parameter which are the heat
transfer coefficient, thermal conductivity, Reynolds number, volume concentration
fraction and rate of heat transfer of Nano-fluid.
DMF induced self assembled gold nanostructures

Neha Sharma, Lalita Sharma, Parita Patel, Abhitosh Kedia*
Department of Physics, Uka Tarsadia University, Maliba Campus, Bardoli, Gujarat
394350
Molecular dipole induced self organization of gold nanoparticles into plasmonic
nanochain networks were fabricated insitu via novel RT colloidal synthesis procedure.
We explore stable assembly of gold nanoparticles in single step process by introducing a
simple chemical synthesis in which pH changed gold precursor is added to
dimethylformaamide (DMF) solution at room temperature. The role of DMF more than a
solvent in determining the final morphology of the particle is studied along with
modulation of the optical response in dmf base metal nanoparticle colloid with tuneable
size and shape. An exciting surface plasmon resonance phenomena of the pure gold
nanoparticles in the reactive solvent is examined via UV- Vis spectroscopy reveal exciting
changes to SPR peaks according to synthesis time as well as with pH of gold precursor.
Normal aging imparts better coupling seen through LSPR shift from visible to NIR region
further confirmed by TEM images. DMF reduction not only facilitates Au nanoparticles,
but also manoeuvre pH assisted intra/inter molecular linear coupling forming small
plamonic chain networks provides unique strategy to promote complex sub-wavelength
optical waveguides and nanophotonic devices.
78
A Review on Synthesis Methods of Activated Carbon

and its Applications
Prinkal Patel*, Vaibhavi Solanki, Riddhi Desai
Department of Physics, Uka Tarsadia University, Bardoli-394350, Gujarat
Activated carbon is having a larger pores size than normal carbon. Because of this
characteristic, the surface to volume ratio of material increases leading to high
absorption capacity. The Activated Carbon can be synthesized using raw materials such
as wood, rice husk, coal, peat, sugarcane bagasse, coconut shells, neem leaf etc. To
enhance the efficiency of the Activated Carbon, one needs to increase the pores size.
Carbonization and activation are two major processes used to prepare Activated Carbon.
The Activated Carbon has a vast range of application such as distilled alcoholic beverage
purification, fuel storage, gas purification, chemical purification, mercury scrubbing etc.
The paper reviews the synthesis methods and its applications in industries, medical
science environmental science and analytical chemistry.
Synergistic antimicrobial activity of silver nanoparticles

synthesized by Dioscorea
Nikunj Khunt, Kaushik Kakadiya, and Sougata Ghosh
Department of Microbiology, School of Science, RK University, Kasturbadham, Rajkot –
360020, India
Biological route for synthesis of nanoparticles is considered as environmentally benign
and non-toxic way to synthesize novel nanomedicine. Hereby, we have employed
Dioscorea bulbifera tuber extract for synthesis of silver nanoparticles, which completed
within 5 h. Optimization studies revealed that 0.7 mM of AgNO3 is optimum for maximum
synthesis of AgNPs at 50 °C. High resolution transmission electron microscopy exhibited
smaller and spherical AgNPs at a range of 3 to 20 nm. However, exotic shapes of AgNPs
like hexagons were also seen. Energy dispersive spectroscopy and X-ray diffraction
spectroscopy confirmed the elemental composition of AgNPs while fourier transform
infrared spectroscopy showed involvement of O-H group of phenols/alcohol in
bioreduction and stabilization process. Further, biochemical analysis showed the presence
of phenolics, starch, diosgenin, reducing sugars, ascorbic acid and citric acid. AgNPs
exhibited superior antimicrobial activity against test organisms like Acinetobacter
baumannii, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus
aureus. Synergy in combination with β-lactam (piperacillin) and macrolide (erythromycin)
antibiotics showed a 3.6-fold and 3-fold increase, respectively, against multidrug-resistant
Acinetobacter baumannii. Similarly, remarkable synergy was observed in combination
with chloramphenicol or vancomycin against Pseudomonas aeruginosa. AgNPs in
combination with streptomycin showed remarkable synergy against E. coli. The above
study strongly proves that combinatorial therapy of AgNPs and antimicrobial agents can
prove to a powerful strategy against multidrug resistant pathogens.
79
Study of PbS Thin Films Prepared by Dip Coating Method

Ravina Anghan*, Sagar Patoliya, Kinjal Patel, Jaymin Ray
Lead Sulphide (PbS) is a P-type semiconductor having direct band-gap and a large
excitation Bohr radius of 18 nm. PbS is widely used in solar cells, photo detectors, optical
filters, gas sensors etc. In literature deposition of PbS thin film is reported by various
physical and chemical methods such as chemical bath deposition, electro-deposition, dip
coating, thermal evaporation, molecular beam epitaxy etc. Among these methods,
solution growth technique is beneficial because it is easy to set up and costly instruments
such as vacuum systems are not required. Particularly, dip coating is a simple and low-
cost method for thin film preparation. The dip coating method consists of major two
steps; (i) dip casting of substrate into the precursor solution and (ii) thermolysis of the
film. These steps are repeated multiple times to attain the desired thickness. Here, we
have successfully synthesized PbS thin films using low cost dip coating method. Lead
acetate is used as lead source; Thiourea is used as Sulphur source and Methanol is used
as solvent for preparation of PbS thin film. The structural and optical properties of the
prepared films are analyzed using X-Ray Diffraction (XRD) profiles, Raman Spectroscopy
and UV visible spectroscopy. XRD profiles of the prepared films reveals pure cubic phase.
UV-visible spectroscopy reveals the direct band gap of the prepared film.
Structural characterization of Lead Sulfide

(PbS) nano crystalline Material
Sweety Panchal, Jaymin Ray*, Kinjal Patel
Department of Physics, Uka Tarsadia University, Bardoli - 394601.
PbS is (VI-III) groupof inorganic material which has optical band gap of 0.5-2.0 eV and
hence, it has wide application in many optoelectronic devices such as photodetector,
solar cell,gas sensor, etc. The structural prpperties of lead Sulfide (PbS) nano crystlline
grown by solid state reaction method and are investigated by X-Ray differaction. In the
present work we have used Lead Acetate as a Lead source. For sulfer Sources we Have
used four inorganic compound Viz Thiourea. The brode peak of ( 1 1 1 ) and ( 2 0 0
)plane from XRD pattern suggests the prepared material is in nano crystalline nature.
80
Heavy Metal Removal Techniques From Waste Water- A Review

Vaibhavi Solanki, Prinkal Patel
Heavy metals are widely used in textile industries during manufacturing and processing.
Heavy metals are toxic water pollutant. Their mobility in the aqueous ecosystem affects
mankind, animals and vegetation. Heavy metals are not only toxic but they are non-
biodegradable also. Thus, removal of heavy metals from the effluent is one of the major
quests to the research community. There are noticeable methods which include heavy
metal removal from wastewater in literature. This paper reviews the recent methods used
to remove heavy metal from wastewater such as chemical precipitation, ion exchange,
adsorption, membrane filtration, coagulation, flotation and electrochemical treatment etc.
Extraction of natural dye from beetroot by

using ultrasound
Jinal M. Pandya , Amrutlal L. Prajapat *
There is a growing demand for eco-friendly/non-toxic colorants, specifically for health
sensitive applications such as coloration of food & dyeing of child textile/ leather
garments. Recently, dyes derived from natural sources for these applications have
emerged as an important alternative to potentially harmful synthetic dyes & pose need
for suitable effective extraction methodologies. The present work focus on the influence
of process parameters for ultrasound assisted extraction of colorant from plant
materials. In the present work, extraction of natural dye from beetroot using ultrasound
has been studied. The use of ultrasound is found to have significant improvement in the
extraction efficiency of colorant obtained from beetroot. Here as a solvent, water has
been used. So, after extraction of colorant, beetroot can also use for other food
applications. The present study clearly offers efficient extraction methodology from
natural dye resources such as beetroot with ultrasound. Thereby, also making eco-
friendly non-toxic dyeing of fibers a potential viable option.
81
L-alanine induced thermally stable self-healing guar gum hydrogel

as potential drug vehicle for sustained release of hydrophilic drug
Swati sharma1, 2 , Pallavi jain2 , Garima pandey2 , Neeraj kumar2 , Rajesh kumar1*
1Institute of Science, Banaras Hindu University, Varanasi-221005, (UP), India,
2Department of chemistry, SRMIST-Delhi-NCR campus, Modinagar, Ghaziabad
Hydrogels are 3D polymeric networks, which are hydrophilic and cross-linked via covalent
or non-covalent interactions. Because of their soft nature with similar physical properties
to soft tissues attracts more attention in biomedical application but due to its weak
mechanical strength and non-healable nature, its application are still restricted in
biomedical field. This article introduces a simple approach of preparing self-healable guar
gum-graft-acrylic acid (GG-PAA) hydrogel using first time L-alanine as a cross-linking agent
which alters the various properties of hydrogel such as mechanical strength (G’=90,570Pa).
A series of guar gum (GG) based hydrogel were synthesized by varying the concentration of
L-alanine (from 0.4-1% w/v) which was used as a cross-linking agent. Hydrogel was
characterized by HRSEM and Rheology studies which explore the morphology and
mechanical strength of hydrogel; further it was investigated that synthesized GG based
hydrogel showed good swelling ability with excellent self-healing property. The highly
water soluble drugs have a tendency to burst rapidly into human body which is undesirable
and thus, this hydrogel may be helpful to overcome this problem too and found fruitful
applications in biomedical field.
Keywords: Hydrogel, L-alanine, self-healing, Rheology, drug delivery.
Synthesis of some novel Heterocyclic compounds &

Its antimicrobial activity.
Divy Patel, Akash Patel, Jeet Makadiya, Bhavesh Sharma & Nilesh Pandya
Laboratory of Bio-organic Chemistry, Department of Chemistry, Uka Tarsadia
University, Bardoli – 394350. Gujarat , India.
Schiff bases derived from various heterocycles were reported to possess cytotoxic,1
anticonvulsant,2 antiproliferative3 , anticancer and antifungal activities.4 Mannich
reaction is an important tool for synthesis of novel compounds. A process for preparing
2-(4'-aminophenyl) 5-amino benzimidazole, a known intermediate used in the synthesis
of azo dyes, is disclosed wherein p-nitrobenzoic acid is condensed with aniline, and the
N(4'-nitrobenzoyl) aniline produced is dinitrited to N(4'-nitrobenzoyl) 2,4-dinitroaniline;
the latter is reduced to the corresponding triamine, which, upon cyclodehydration,
results in the 2-(4'-aminophenyl) 5-amino benzimidazole.
Keywords:- Schiff Base, Benzimidazole, Antimicrobial Activity.

Tarafder, M. T.; Kasbollah, A.; Saravan, N.; Crouse, K. A.; Ali, A. M.; Tin, O. K. J. Biochem.,
Mol. Biol. Biophys. 2002, 6, 85
Kucukguzel, I.; Kucukguzel, S. G.; Rollas, S.; Sanis, G. O.; Ozdemir, O.; Bayrak, I.; Altug, T.;
Stables, J. Il Farmaco. 2004, 59, 839.
Vicini, P.; Geronikaki, A.; Incerti, M.; Busonera, B.; Poni, G.; Kabras, C. A.; Colla, P. L. Bioorg.
Med. Chem. 2003, 11, 4785.
Pignatello, R.; Panico, A.; Mazzane, P.; Pinizzotto, M. R.; Garozzo,A.;Fumeri,P.M.Eur.
J.Med.Chem.1974,29, 781.
82
Calcium Chloride An Efficient Catalyst For Synthesis of 1,5-

Benzodiazepine and its derivatives
Akshay S.Ranpise, Pramod Kulkarni*
Post graduate Department of Organic Chemistry, Hutatma Rajguru Mahavidyalaya,
Rajgurunagar, Pune-410505
Benzodiazepines are heterocyclic compound constitute a significant class of biologically

active compounds. The synthesis of these molecules has been receiving much attention in
the field of medicinal and pharmaceutical chemistry. Benzodiazepines show important
medicinal properties such as anticonvulsant, anti-inflammatory, analgesic, hypnotic and
sedative. The derivatives of 1,5-benzodiazepines are also used as dyes for acrylic fibres in
photography. Benzodiazepines are generally synthesized by the condensation of o-
phenylenediamine with ketone, α, β-unsaturated ketone or β-haloketone. Here, we
reported the synthesis of 1,5-benzodiazepines by the condensation reaction between o-
phenylenediamine and 2 moles of ketone using calcium chloride as catalyst. The merits of
this method are short reaction time, high yield, inexpensive and easily available catalyst,
simple workup procedure.
Functionalization of the Chalcone Scaffold for the Discovery of

Novel Lead Compounds Targeting Microbe Infection
Shiv V Kantariya, Hinal K Patel, Anand P Mistry and Paresh N Patel*
Laboratory of Bioorganic Chemistry, Department of Chemistry,
UkaTarsadia University, Bardoli – 394 350, Gujarat, India
The occurrence of invasive fungal infections represents a substantial threat to human
health that is particularly serious in immunocompromised patients. The limited number of
antifungal agents, devoid of unwanted toxic effects, has resulted in an increased demand
for new drugs. Herein, the chalcone framework was synthesised and functionalized to
develop new antifungal agents able to interfere with cell growth and with the infection
process. Thus, a small library of chalcone-based analogues was prepared and
characterized by various spectroscopic techniques, i.e. NMR, HRMS, single crystal XRD, etc.
Indeed it has be reported thet, these compounds combine two modes of action by
selectively interfering with growth and, as an added value, weakening microbial virulence.
Overall, these compounds could be regarded as promising antifungal candidates worthy of
deeper investigation. They also provide a chemical platform through which to perform an
optimization process, addressed at improving potency and correcting liabilities.
Reference: Paresh N Patel, et. al., J Chem Crystallogr (2016) 46: 245.
83
Cascade Reaction in the Synthesis of Heterocyclic

Natural Products
Siddhi V Desai, Anina D Patel, Tina J Ahir and Paresh N Patel*
Cascade reactions, as an attractive branch of organic chemistry, have been the subject of
intense research in the recent years. In these reactions numerous transformations occur
in a single sequence, and the subsequent reactions are formed as a consequence of the
functionality of the previous step. Cascade reactions are environmentally benign
processes due to their one-pot procedure which accordingly proceed in a single reaction
solvent, work-up, and purification step. Therefore, they are often associated with cost
savings in terms of solvents, catalysts, and reagents in addition to time and effort. In the
recent years, cascade reactions have been used for the construction of complicated
molecular scaffolds, especially heterocyclic natural products. Different pyrimidone based
heterocyclic compounds were synthesized through cascade (tandem) reactions and
characterised by various spectroscopic techniques, i.e. NMR, HRMS, IR, XRD, etc. This
abstract for poster presentation has been focused on the use of cascade sequences for the
synthesis of heterocyclic natural products.
Reference: Paresh N Patel, et. al., Tetrahedron, 74, 1, 2018, 204-216.
2-Oxo Group assisted Synthesis of Tetrahydrofuro[3,2-d]oxazoles

and Furanones
Ankit Patil,a , Shivani Tandel,a Satyanarayana Battula*a
a Department of chemistry, Uka Tarsadia University, Bardoli, Surat, Gujarat-394350.
Presenting an efficient microwave assisted synthetic approaches to tetrahydrofuro[3,2-

d] oxazole and furanones. Furthermore, this method accomplished diastereo selective
synthesis of tetrahydrofuro [3,2-d] oxazole. Here, metal catalyzed reaction produces
furanones and metal free method produce tetrahydrofuro[3,2-d]oxazoles by the
reaction between 2-oxoaldehyde, pyrrolideine and β-napthol.
84
Design and development of polysaccharide based new

biodegradablefilms: A comparative study
Anuraag A Moturi,aDharmesh R Chejara*a
aDepartment of Chemistry, UkaTarsadia University, Bardoli, Gujarat, India – 394350
The dissertation is a comparative study between two different methods for the
preparation of biodegradable films based on polysaccharide.Biodegradable films were
prepared using sodium alginate (SA) and carboxymethyl cellulose (CMC) as main
components of the film. In study one, film was obtained using the blend of these two
polymers followed by addition of CaCl2 as a cross-linking agent and glycerin as a
plastisizer. In study two sodium alginate/carboxymethyl cellulose (NaCMC)-based bio-
composite films were prepared by solution casting method and process has been
optimized in terms of weight ratios of these polymers (i.e. 1.5% sodium alginate and
1.5% NaCMC). The optimum combination was selected on the basis of good tensile
strength and low moisture sensitivity, Further this film was treated with aqueous
solution of potassium aluminium sulphate (potassium alum) to reduce water vapour
permeability and moisture content. In both the study the mechanical and
physicochemical properties have been improved. Film biodegradability was not affected
either due to the cross linking or by alum treatment. The designed films may have
potential applications to be a substitute for the currently used polyethylene-based films.
Synthesis and studies on antimicrobial activity of Piperidine

containing Pyrimidine derivatives
Bipin V. Devani , Hirendra K. Bhagatwala , Dipak M. Vashi
Narmada college of science and commerce , Bharuch
A new series of (E)-N-(4-(substitutedbenzylideneamino)phenyl)-4-piperidino-6-

(trifluoromethyl)pyrimidin-2-amine have been synthesized from various substituted
aldehyde N1 -(4-piperidine-6-(trifluoromethyl) pyrimidin-2-yl)benzene-1,4-diamine by
refluxing it in methanol and acetic acid. They were characterized by elemental analysis,
IR and PMR spectroscopy. The newly synthesized compounds were screened for their
antimicrobial activity. Some of the compounds showed moderate to significant activities.
Key words: piperidine, pyrimidine, Schiff Base, antimicrobial.

85
Efficient Red Emitters based on TTA Antenna fusedEu(III)

Complexes and their Photophysical Analysis for OLEDs
Applications
Babita Patil and Rajamouli Boddula*
Department of Chemistry, Uka Tarsadia University, Bardoli, Surat, Gujarat
Luminescent materials gained immerse importance in the field of display devices and
biological field. Research on highly emissive red and blue phosphors for warm white LEDs and
smart full color displays are highly imperative. To achieve the same a great deal of effort has
been devoted to syntheses of Ln complexes due to their unique optical properties (a line like
(4f-4f) emission spectrum and capable emitting different spectral windows). Among all Ln
complexes, red-emitting phosphorescent emitters (Eu(III) complexes) are efficient and widely
used in OLEDs and LEDs. Unfortunately, low absorption coefficients or oscillator strength of
lanthanides restricts the use of practical applications; however the same can be overcome by
using antenna effect (IQE up to 100%). In the present study, the design strategy of ancillary
ligands for obtaining highly emissive Eu complexes as well as single molecule white emissive
Eu complexes.
The complexes are characterized by NMR, Mass, FT-IR and elemental analysis. Thermal
stability, photophysical, electrochemical and theoretical analysis was carried out. The fully
energy transfer process leads to the efficient characteristic red emission at 612 nm and
partial energy transfer leads to tunable emission (in different polarity of solvents), which
gives the white emission by balancing the red, blue, green (RGB) emission. The detailed
results will be presented and discussed.
Key Words : Fluorene, bipolar, antenna, Eu3+ metal ion.
Phenazines and Thiazine: Green Synthesis, Photophysical

Properties and Dichroic Behavior in Nematic Host
*Dr Sharad Patil, Karan S. Patel ,Triguna P Patel and Dhruvkumar G Dhimmar
Department of Chemistry, UkaTarsadia University, Bardoli – 394 350, Gujarat, India
An efficient, mild and environmental friendly protocol is Develop for synthesis of

Phenazines and Thiazine from laws one under ultrasound irradiation in an aqueous
media. Short reaction time, ambient mild reaction conditions, simple work up and high
yield are the striking features of the present protocol. The photo physical properties of
the synthesized Phenazines and Thiazine are evaluated. Density functional theory (DFT)
and time dependent density functional theory (TDDFT) computations. The functional
used is B3LYP and the basis set 6-31G(d) is used for all the atoms. There is a close
agreement between the experimentally observe absorption-emission values and the
compute vertical excitation and emission values. The Dichroic ratio and order parameter
of the dye in nematic liquid crystal (LC) host is calculate. The Anthraquinone fused
Phenazine system is find to exhibit dichroism due to varying absorption under the
electric vectors of incident light, polarized parallel and perpendicular with respect to the
LC director
86
Colorimetric sensing ability of vitamin B6 based receptors

towards Fluoride sensing
a*Darshana A Rana, bS.K. Sahoo, cAniruddhasinh. M. Rana, cJigar R Patel
a Sheth P.T. Mahila Arts and Science College, Surat, Affiliated to VNSGU, Surat
bS.V. National institute of Technology, Surat.
c AEPS Institute of Science, Ankleshwar, Affiliated to VNSGU, Surat.
A simple colorimetric sensor L was prepared through condensation reaction and showed
naked eye colour change from colourless to light yellow brown, and was selective towards F-
anion in DMSO with a stability constant of 1.876358 x 106 M-1. Jobs plot suggested that it
binds F- anion in 1:1 ratio. Besides this it showed real life analysis with toothpaste and on test
paper kit, which ensured the ability of the receptor to detect fluoride in the field of food and
healthcare industries as well as in other bio-relevant purposes.
HO
N
N
H2N
OH
Development of sustainable technologies with practical

approaches on textile waste water dyes removal
Deepika S Gatt and Paresh N Patel*
Textile industry discharges large amounts of highly colored wastewater, using chemicals
reagents within its industrial processes. Discharge of these effluents in open water
bodies represents an environmental and aesthetic problem and it may also limit
photosynthesis in aquatic plants. Many treatment alternatives have been reported in
laboratory as well as full scale, including physical, chemical, biological, Advanced
Oxidation Process (AOP) and a combination of them. We are working on development of
sustainable nano-technology with preatical approach in textile waste water dyes
removal. In order to develop technology, we have synthesised bio mediated gold nano
particles and using them as a sustainable catalyst for the degradation of dye molecules.
This abstract of presentation aims to put together extensive information about dyes and
the best available technologies (BAT) for their removal from textile effluents.
Reference: Markandeya, et al., Journal of Cleaner Production, 149, 2017, 597-606.

87
Decolourization of Methyl red using Calsium Hydroxide and

Ferrous sulphate
Dipa H. patel, Amrutlal Prajapat*
Water effluents from textile industries are a major source of water pollution. This waste
streams contain numerous toxic dyes, which are harmful for aquatic life. Therefore, there is a
need to find economical and bio-friendly methods to degrade textiles dyes. In this study,
methyl red dye was used for degradation using ferrous sulphate and calcium hydroxide as a
flocculants. The oxidation and subsequent degradation of the dye was found to be dependent
on both, the amount of Fe+2 ions as well as calcium hydroxide. A systematic study was
carried out using 10 different sets of methyl red solution with various doses of flocculants.
Optimization of dose was also studied and it has been found that the rate of degradation was
enhanced with dose of flocculants, whereas some had an inhibitory effect. The rates of
degradation were found to fit to first order kinetics. After the treatment of dye, analysis was
studied using UV-visible, conductometer and pH-meter.
Metal catalysed microwave assisted green synthesis of coumarin

derivatives via pechmann condensation
Jignesh P Raval*a, Dipen H Desaib , Shivani N Tandelb, Nisha Odedarab
a The Mandavi Education Society, Mandavi-394160, Gujarat, India.
bDepartment of chemistry, Uka Tarsadia University, Bardoli-394350, Gujarat, India.
Presenting an efficient microwave assisted solvent free synthetic approaches for

coumarin derivatives using metal catalyst via pechmann condensation. The
synthesized compounds were characterized by IR, 1 H-NMR, 13C-NMR and elemental
CHN analysis. The proposed microwave assisted solvent free synthesis on inorganic
support provide the products in high yield with shorter reaction time, quick and easy
isolation of product and excellent chemoselectivity. The products were tested for
antimicrobial activity.

Polymeric materials containing heterocyclic ring in the main chain were synthesized by
high temperature polycondensation reaction of substituted s-triazine and different diols.
All polymers were obtained in good yield and were characterized by solubility, viscosity
measurement, FTIR and NMR spectral analysis. Thermal stability was studied by TGA
technique. The synthesized polyester showed good thermal stability along with good
solubility in common organic solvent.
88
One-pot Synthesis of Some Anti-proliferative Pyrazolyl–

dibenzo[b,e][1,4] diazepinone Scaffolds at room Temperature
Hiralben D. Atara,a Gaurangkumar C. Brahmbhatt,a Narsidas J.
Parmar,a* Vivek K. Gupta,b Irene Lagunesc, José M. Padrónc
aDepartment of Chemistry, Sardar Patel University, Vallabh Vidyanagar-
388120, Dist. Anand, Gujarat, India
One-pot syntheses of some aryl(oxy/sulfanyl)-pyrazolyl-dibenzo[b,e][1,4]diazepinone
scaffolds have been achieved in the presence of indium chloride in acetonitrile, at room
temperature, assembling 5-aryl(oxy/sulfanyl)-3-methyl-1-phenyl-4-carbaldehydes with
cyclic diketones and aromatic diamines. The method is highly efficient to achieve all the
products excellent in purity without use of chromatography. IR, 1H-NMR, 13C-NMR
spectroscopy and the Single crystal X–ray diffraction studies were made and used to
confirm all proposed structures. FRAP (ferric reducing anti–oxidant power) method was
used to evaluate anti-oxidant power of the compounds. A panel of six different human
solid tumour cell lines A549 (lung), HBL–100 (breast), HeLa (cervix), SW1573 (lung), T–
47D (breast) and WiDr (colon) was used to determine anti-proliferative activity of all the
heterocycles, also. The results are promising in many cases.
α-Oxo Group Promoted Catalyst Free Reactions:

Hydrophosphonylation & Aerobic Intramolecular Nucleophilic
Displacement Reaction
Komal Patela, Satyanarayana Battulaa *
Reporting the highly efficient catalyst free approaches for the hydrophosphonylation &
aerobic intramolecular nucleophilic displacement reactions and that has been described
for the synthesis of α-hydroxy-β-oxophosphonates (HOP) and α-oxoesters (OE)
respectively. The presence of 2-oxo group in α-oxoaldehydes (OA) was a key factor in
promoting the reaction of tervalent phosphite form towards activated aldehydes (OA).
Consequently, the α-C-H atom of HOP activated in situ and sustains intramolecular
oxidative nucleophilic displacement (IND) in a unique way to α-oxoester (OE).
Mechanistic studies pointed towards generation of OE from HOP through 1,2,3-
dioxaphosphetan (DOP) intermediate using novel air (O2 ) promoted IND reaction under
in situ generated acidic environment.
Key words: α-oxo group, hydrophosphonylation, IND process, DOP, Phosphonates

89
Tuning, Reshaping and Self-Organization of Gold Nanostructures

Abhitosh kedia, Hitesh V Rajput
Department of Physics, Uka Tarsadia University, Bardoli, Surat-394350, Gujarat, India
Understanding the nature of localized surface plasmons (LSPs) that occur at the
geometrically bounded surface of anisotropic metal nanoparticles in focalizing the
enhanced electromagnetic fields increases with the advent of more complex/exotic
nanostructures. Recently, variety of metal archimedean solids were obtained utilizing
the mild reducing as well as stabilizing effect of the amphiphilic polymer, poly vinyl
pyrrolidone (PVP). The most interesting aspect 'universal solubility' of these PVP coated
metal nanoparticles, which has not been looked upon carefully till now, has been
effectively utilized in our present synthesis approach for size tuning as well as reshaping
along with self-organization with exceptional colloidal monodispersity, thereby provides
a relatively simple but effective paradigm for the easy fabrication of plasmonic
metamaterials. The precise morphology correlated plasmonic signatures before and
after tuning/reshaping of these as-prepared gold nanostructures in the presence of
foreign agents were extensively studied using electron microscopy and spectroscopy
measurements in detail. The modified electron density distribution around both
nitrogen and oxygen components of PVP molecules in the different surrounding reaction
medium or in the presence of foreign ions were detailed through systematic FTIR, and
NMR studies, signifying the strong structure correlated plasmonic eigen modes,
illustrating the direct visualization of plasmons and their intriguing hybridization
mechanism in complex size/shaped metal nanostructures encourage us to quantitatively
identify the efficient plasmonic coupling mechanisms.
Synthesis and studies on antimicrobial activity of Piperazine

containing Pyrimidine derivatives
Hirendra K. Bhagatwala , Bipin V. Devani , Dipak M. Vashi
Narmada college of science and commerce , Bharuch
A new series of 2-(4-benzylpiperazin-1-yl)-N’-(5-bromo-2-(substitutedpiperazin-1-

yl)pyrimidin-4-yl)acetohydrazide have been synthesized from 2-(4-benzylpiperazin-1-
yl)acetohydrazide, 5-bromo-2,4-dichloro pyrimidine and various substituted piperazine
in n-methylpyrrolidinone in presence of diisopropylethylamine. They were
characterized by elemental analysis , IR and 1H NMR spectroscopy. The newly
synthesized compounds showed moderate to significant activities.
90
Design, synthesis and in-vitro antimicrobial evaluation of

Schiff's bases derived from Benzotriazole-1,3,4-Oxadiazole
Keyur M. Pandya1, Parth J. Naik2, Piyush S. Desai*3
1,3Department of chemistry, Arts, Science and Commerce College, Veer Narmad South
Gujarat University, Surat-394185, Gujarat, India.
2 Department of Chemistry, Uka Tarsadia University
Heterocyclic compounds play an important role in medicinal chemistry. Motif such as

Schiff base is routinely observed in several compounds of pharmacological interest.
Several natural products also contain these motifs in them. We have undertaken a library
synthesis of (1H-benzo[d][1,2,3]triazol-5-yl)(phenyl)methanone clubbed 1,3,4-
oxadiazole derivatives bearing substituted Schiff base moiety were synthesized. We have
synthesized a collection of 14 compounds and characterized by elemental analysis, MS,
1H NMR and 13C NMR spectral data and were screened, against bacterial pathogens.
where the majority of these compounds antibacterial and antifungal activities against the
tested strains of bacteria and fungi compared with the reference drugs. Compounds
106d, 106e and 106p showed potency (MIC 62.5 µg/mL) against E. coli and P.
aeruginosa bacterial strain compares to standard drug Ampicillin (MIC 100 µg/mL)
whereas, against C. albicans compounds 106d (MIC 100 µg/mL), 106e (MIC 100 µg/mL)
and 106p (MIC 100 µg/mL) showed similar activity with reference to standard drug
Nystatin (MIC 100 µg/mL) and against A. Niger fungi compounds 106l (MIC 100 µg/mL),
106m (MIC 100 µg/mL), and 106n (MIC 100 µg/mL) showed similar activity compare to
standard drugs Nystatin (MIC 100 µg/mL) and Griseofulvin (MIC 100 µg/mL). Thus,
these studies suggest that (1H-benzo[d][1,2,3]triazol-5-yl)(phenyl)methanone clubbed
1,3,4-oxadiazole derivatives bearing Schiff base moiety are interesting scaffolds for the
development of novel antimicrobial agents.
Synthesis and characterization sodium alginate

based new ester conjugates
Lalit M Sangania,Sagar N Chovatiyaa, Dharmesh R Chejara*a

aDepartment of Chemistry, Uka Tarsadia University, Bardoli, Gujarat, India – 394350
Sodium alginate was chemically modified to ester conjugates using carbodiimide

chemistry. Synthesized derivatives were characterized using proton NMR, infrared (IR)
spectroscopy and differential scanning calorimetry (DSC). These Synthesized conjugates
were prepared by using propyl alcohol and amyl alcohol as alcohol moiety for the ester
formation and DCC was used as a coupling agent. Further these conjugates were
optimized in terms of mole ratio and were used for dye adsorption study to have some
potential application as adsorbent. The results suggest the approach of developing such
chemically modified conjugates- may have possibility of achieving some new materials
for dye adsorption application.
91
Development of sustainable methodology in Asymmetric

Reduction of Ketones with Biocatalysts
Vishal R Lukhi, Mayur J Patel, Nilam D Mahla and Paresh N Patel*
Chiral alcohols are the key chiral building blocks to many enantiomerically pure
pharmaceuticals. The biocatalytic approach in asymmetric reduction of corresponding
prochiral ketones to the preparation of these optically pure substances is one of the most
promising routes. The stereoselective reduction of different kinds of prochiral ketones
catalyzed by various plants and microorganisms was studied in this work. We are trying to
develop sustainable bio-catalyst based methodology for the quantitative reduction of
ketones in to optically pure chiral alcohols. Various optimization studies were in order to
enhance the yield and ee of the product. Initial data will be presented as a poster the the
said symposium.
Reference: Kaoru Nakamura, Tetrahedron: Asymmetry, 14,18, 2013, Pages 2659-2681
Synthesis and optical response to acids and bases of a new

styryldihydro-benzo[a]phenazine chromophores
Sharad R. Patila, NidhiJ. Patel*a, Anjali H. Patel*a, DarshanL. Vaghashiya *a
Department of Chemistry, Uka tarsadia university, Bardoli, Gujarat, India - 394350
Four novel styryl-dihydrobenzo[a]phenazine chromophores have been synthesized and

spectroscopically characterized. They respond to acids and bases through changes in
absorption resulting in strong bathochromic shift (>437 nm). The emission quantum
yields of the dyes were in the range0.11-0.14. Computational studies have been
performed to provide further insights into the nature of electronic transitionsfor the
synthesized dyes. The qualitative trends observed in the optical properties,
halochromism and geometrical isomers were supported by density fictional theory (DFT)
computation.
92
Multicomponent Reactions for the Synthesis of Heterocycles; Greener

Approach in Organic Synthesis
Priyanka J Parmar, Nidhi H Prajapati, Tarun I Dhimmar and Paresh N Patel*
Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the
synthesis of versatile heterocycles, particularly those containing structural diversity and
complexity, by a one-pot operation. These reactions can dramatically reduce the
generation of chemical wastes, costs of starting materials, and the use of energy and
manpower. Moreover, the reaction period can be substantially shortened. We have
synthesised several cyclohexanol derivatives by MDRs. All the prepared molecules are
characterised by various spectroscopic techniques, i.e. NMR, HRMS, Single Crystal XRD.
This presentation covers recent advances on multicomponent domino reactions for the
construction of five-, six-, and seven-membered heterocyclic skeletons and their
multicyclic derivatives.
Reference: Paresh N Patel,

et al., Tetrahedron;
74, 1, 2018, 204-216
Copper Catalyzed Ortho-Functionalization of Phenols with 2-

Oxoaldehydes to Product 2-Hydroxyphenyl-1,2-diones
Siddhant Shah, Nitesh Pareek, and Dr. Satyanarayana Battula*
Department of Chemistry, Uka Tarsadia University, Bardoli-Mahuva Road,
Tarsadi-394 350
An efficient procedure for the synthesis of 2-hydroxyphenyl-1,2-diones, by the reaction

between 2-oxoaldehydes and phenol, catalyzed by the copper(II). This method proceeds
through the ortho-functionalization of phenols. The product 2-hydroxyphenyl-1,2-diones
is obtained to a high standard.
93
Synthesis and evaluation of antimicrobial activity of novel 5-

arylidene-thiazolidine-2,4-diones
Payal, Joshia, Dharmesh, Mahajan*b, Dharmesh, Chejara a
(a) Department of Chemistry, Uka Tarsadiya University, Surat- 394350, Gujarat, India
(b) Department of Chemistry, Government Science College Vankal, Surat-394430,
Gujatat, India
A series of novel 5-arylidene-thiazolidine-2,4-diones were synthesized by the knoevenagel
condensation of aromatic aldehydes with N-substituted thiazolidinedione-2,4-diones by using
Alum KAl(SO4)2·12(H2O) which is an inexpensive, non toxic and efficient catalyst.
Substitution of arylidine at position 5 on the thiazolidine nucleus were synthesized and tested
against Gram-positive, Gram negative bacteria and one fungal strain for antimicrobial
activities. All synthesized compounds showed moderate to very good activity against
microorganism.
Biginelli Reaction
Dr. Sharad Patil* Pratik Pipaliya, Pooja Rathod, Yash Mehta
Department of Chemistry; Uka Tarsadia University; Bardoli - 394350
Ionic liquids have increased popularly in last couple of decades as solvent for its greener
approach. Here a novel three-component, one-pot condensation yielding 4-phenyl-3,4
dihydrobenzo[g]quinazoline-2,5,10(1H)-trione is reported in halogen free ionic liquid
(HFIL). Components of reaction are aldehyde, urea, and β-keto esters in presence of HFIL
Nmethyl- 2-pyrrolidonium hydrogen sulfate [HNMP]+[HSO4]−. Comparative reactions
were performed under conventional heating and sonication in HFIL. Solvent utility of HFIL
makes purification and separation process artless task offering an advantage of five times
recyclability without degrading its activity. The use of HFIL is advantageous over
conventional solvent due to very short reaction time and halogen-free volatile solvent
utility and recyclability. Latterly these compounds applied as disperse dye on polyester and
nylon fiber were found to give moderate color and fastness properties.

Department of chemistry, Uka Tarsadia University, Bardoli-394350, Gujarat, India.
Polymeric materials containing heterocyclic ring in the main chain were synthesized by high
temperature polycondensation reaction of substituted s-triazine and different diols. All
polymers were obtained in good yield and were characterized by solubility, viscosity
measurement, FTIR and NMR spectral analysis. Thermal stability was studied by TGA technique.
The synthesized polyester showed good thermal stability along with good solubility in common
organic solvent.
94
Solubility and thermal study of polyesters containing

coumarin ring in the main chain
Kamlesh D. Prajapatia Pramod M. Gamitb & Vidhya V. Patelb
a Department of chemistry, V. S. Patel arts & science college, Bilimora-396321, Gujarat, India.
b Department of chemistry, Uka Tarsadia University, Bardoli-394350, Gujarat, India.
Polyesters containing coumarin ring in the main chain were synthesized by high
temperature polycondensation reaction using cetrimide as an initiator. The synthesized
polyesters were characterized by various techniques like FTIR, NMR and fluorescence.
The inherent and reduced viscosities were checked by ubbelohde solution viscometer. The
relative solubility of these polyesters were determine in a variety of solvents. Thermal
stability was studied by TGA and DTA techniques. The obtained polyesters possess high
thermal stability with good solubility in common organic solvents.
Organocatalyzed Synthesis of Coumarin Derivatives Via

Pechmann Condensation
Rushikesh Mane, Pramod Kulkarni*
Post graduate Department of Organic Chemistry, Hutatma Rajguru
Mahavidyalaya, Rajgurunagar, Pune-410505
Coumarin is a heterocyclic compound, which shows significant role in the natural

product and synthetic organic chemistry. They are widely used as additives in perfumes,
foods, agrochemicals, pharmaceuticals, cosmetics and in the preparation of insecticides.
Coumarin and its derivatives shows various bioactivities such as antimicrobial,
antithrombotic, anticoagulant, antipsoriasis activity, anticancer, anti-HIV, antioxidant
activity. Coumarins also act as intermediates in the synthesis of furocoumarins,
chromenes, coumarones and 2-acylresorcinols. Due to importance of this molecule, many
chemists are attracted towards its synthesis. In literature the synthesis of Coumarins
have been reported by several routes comprising Pechmann, Perkin, Knoevenagel,
Reformatsky, Wittig reactions and by flash vacuum pyrolysis. Among these, the
Pechmann reaction is the most widely used method, as the reaction involves the use of
simple starting materials that is phenols and β-ketoesters in the presence of acidic
condensing agents. This reaction is carried by using Bronsted acid, Lewis acid, Metal salt,
ionic liquid, solid support reagent. Most of these reported methods are suffer from
drawbacks like use of excess amount of catalyst, long reaction times, low yield, and high
temperature. Here, we develop a short and efficient synthesis of coumarins using organic
acid under microwave condition. This method is simple, cost effective, high yield.
95
Synthesis & Characterization of Amoxicillin-Isatin Schiff

Bases and Their In-Vitro Anti-Bacterial Activity
RAVI L. THUMMAR and SUTAPA MONDAL ROY
Department of Chemistry, Uka Tarsadia University, Maliba Campus, Gopal
Vidhyanagar, Bardoli 394350, Gujarat.
Amoxicillin is a broad-spectrum antibiotic drug belonging to the penicillin group. It is use
for treating infections involving both gram-positive and gram-negative bacteria. This
drug inhibits the bacterial DNA gyrase, an enzyme essential for DNA replication. Isatin is
an important class of heterocyclic compounds, which is a derivative of indole.
Compounds consisting of an azomethine group (with the general structure R2C=NR’) are
known as Schiff bases. The immense chelating abilities, of Schiff bases have attracted
extreme attention in terms of analytical and biological applications. Schiff bases of
amoxicillin and isatin, show very significant activity against methicillin resistant
Staphylococcus aureus (MRSA). The new Schiff bases of isatin and 5-bromo isatin linked
to amoxicillin show an interesting antibacterial activity. Amoxicillin are linked directly
through their α-amino groups to the acyl side chain with isatin and isatin derivatives by
nucleophilic addition using glacial acetic acid as a catalyst. The amoxicillin-isatin Schiff
bases were synthesized and characterized on the basis of physical properties,
conductance measurements, elemental analysis, UV/Vis., infrared and nuclear magnetic
resonance spectroscopy. These derivatives were also evaluated for their antibacterial
activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus,
Salmonella typhae, and E. coli. It was found that amoxicillin-isatin Schiff bases are having
more antibacterial activity as compared to the bare drugs.
Electrophilic Cyclization of N-Arylimines through Cu-

Benzotriazole Catalyst: A Methodical Tandem Approach to 4-
Alkoxy quinazolines
Priyanka Gamit,a Satyanarayana Battula*a
An efficient approach to 4-alkoxy quinazolines has been developed via copper-

benzotriazole (Cu-BtH) catalyzed intramolecular electrophilic cyclization of N-arylimines,
achieved through reaction of 2-aminobenzonitriles and various aldehydes. This 4-alkoxy
quinazolines are promising biologically active molecules, as VEGFR-2 kinase inhibitors.
This could be the first synthesis of these molecules from mono cyclic systems. It also
added a conceptual launching of –OR group on quinazolinerings.
96
Therapeutic production of protein C

Saiyed Kashaf F, Gopal Jee Gopal*
CGBIBT, Uka Tarsadia University, Bardoli – 394350, Gujarat, India
Protein C, a blood coagulation factor XIV. It plays an important role in regulating anti-
coagulation, inflammation, maintaining the permeability of blood vessel in human and
other animals. Activated protein contains 419 amino acid in multiple domain. Deficiency
of protein C leads to dangerous blood clot, Deep vein thrombosis (DVT) purpura
fulminans. It may be inherited or acquired. In November 2001 FDA approved
Drotrecogin alfa activated, it is recombinant form of human activated protein C.
It is marketed as Xigris by Eli Lily Company. But in October 2011 Xigris
was withdrawn from the market due to its higher mortality in trial among adults. e-
health statistical ratio shows that 3539 people had serious risk of bleeding among them
422 had died .
My hypothesis is to produce inactivated form of protein C by using
suitable expression system and purify the expressed product by affinity chromatography.
This recombinant product will be administered to deficient patient to reduce mortality
and sepsis, which was caused by activated form of protein C.
Potassium Carbonate An Efficient Catalyst For Synthesis of α,β, γ, δ-

Unsaturated Ketone
Sameer Gawade, Pramod Kulkarni*
Post graduate Department of Organic Chemistry, Hutatma Rajguru Mahavidyalaya,
Rajgurunagar, Pune-410505
Cinnamylideneacetophenones are α, β, γ, δ-Unsaturated Ketone shows important

bioactivity like antibacterial, antitubercular, antinociceptive and anticancer activity.
Cinnamylideneacetophenones are important key intermediates in organic synthesis for
2-benzoyl-1, 5-diphenylpyrroles, 4-aryl-2,3-dihydro-2-styryl-1,5-benzothiazepines,
isoquinuclidines. The cinnamylideneacetophenones are synthesized by calsein Schmidt
reaction between acetophenone and cinnamaldehyde using sodium hydroxide as base
catalyst. Here we report the synthesis of cinnamylideneacetophenones using potassium
carbonate as a base catalyst for condensation reaction between acetophenone and
cinnamldehyde. The merits of this method are short reaction time, high yield, easy work-
up procedure and inexpensive and easily available catalyst.
97
Benz-imidazole based Luminescent Molecular Materials for Sensing

Applications: Combined Experimental and Theoretical analysis
Shivamkumar Bhoye and Rajamouli Boddula*
Department of Chemistry, Uka Tarsadia University, Bardoli, Surat, Gujarat
Photoluminescence is light emission from any form of matter after the absorption of
photons(Electromagnetic radiation). It is one of many forms of luminescence (light
emission)and is initiated by photo excitation (excitation by photons). It can be utilized to
produce the white emission by mixing of the primary colors (RGB). In addition, can be
utilized to find (sensing) the hazards by luminescence quenching process. In the part of
that we have synthesizedBenz-imidazole based blue emissive fluorophores for sensing
application. Fast and reliable chemical sensors for the trace detection of hazardous
chemical species have attracted special attention in recent years due to their possible
applications in environmental cleaning and home land security.
The detection process is based on the luminescence of certain materials, called
luminophores. The sensor transmits invisible UV light at a wavelength of 375 nm. This
excites the luminophores contained in the object so that they emit light in the visible range
of the electromagnetic spectrum.
Luminophores can be attached to labels or mixed with a variety of materials for detection
purposes. Thus, for example, paper contains optical brighteners that are excited by the UV
light and reflect light (mostly blue) to the sensor.
In this work, a new imidazole-based sensitive and selective sensor was synthesized. It was
observed that the synthesized new fluorescent sensor had high selectivity and sensitivity
to picric acid. Currently working on luminescence sensor on Imidazole molecule.
Luminescence is spontaneous emission of light by a substance not resulting from heat; it is
thus a form of cold-body radiation.The synthesized ligand shown blue emission in UV
light. This fluorescence was decreases by using the picric acid. The synthetic procedures
and detailed study will be presented and discussed.
HIGHLIGHTS: Photoluminescence,Sensor.
REFERENCES
[1] J. R. Lakowicz, Principles of Fluorescence Spectroscopy, 70 3rd edn., Springer, 2006.
[2] T. W. Bell and N. M. Hext, Chem. Soc. Rev., 2004, 33, 589-598. [c] H. Lu, L. Xiong, H.Liu,
M. Yu, Z. Shen, F. Li and X. You, Org. Biomol. Chem., 2009, 7, 2554-2558.
Metal catalysed microwave assisted green synthesis of coumarin

derivatives via pechmann condensation
Jignesh P Raval*a, Dipen H Desaib, Shivani N Tandelb, Nisha Odedarab
a The Mandavi Education Society, Mandavi-394160, Gujarat, India.
Presenting an efficient microwave assisted solvent free synthetic approaches for coumarin
derivatives using metal catalyst via pechmann condensation. The synthesized compounds
were characterized by IR, 1H-NMR, 13C-NMR and elemental CHN analysis. The proposed
microwave assisted solvent free synthesis on inorganic support provide the products in high
yield with shorter reaction time, quick and easy isolation of product and excellent
chemoselectivity. The products were tested for antimicrobial activity.
98
In Silico analysis of Cag PAI sequence in Type IV Secretion System

of Helicobacterpylorito generate motif
Gohil Shivani*, Bhrugesh Joshi, Dr. Gopal Jee Gopal
C.G. Bhakta Institute of Biotechnology, Uka Tarsadia University, Maliba Campus,
Bardoli-Mahuva Road, Tarsadi, Dist.Surat, Gujarat, India
Helicobacter pylori, which is spiral, gram negative human pathogen cause infection in
stomach and forms colonies which results in peptic ulcer, chronic ulcer, gastric cancer,
MALT(Mucosa Associated Lymphoid Tissue)and inflammation occurs through
interaction of Vac A(Vacuolating toxin) and Cag A( Cytotoxic associated toxin)with
surface receptor molecule this response in immune inhibition, apoptosis.Cag PAI is 40 kb
genomic region response for pathogenicity in human. It involves type IV secretion system
(T4SS) used to deliver DNA as well as protein substrate from donor to target cell through
conjugation and through pilus formation.To understand how thesesequence is
responsible for pathogenicity which is donethrough computational method, we
haveretrivedHelicobacter pylori sequence such as Hp0522, Hp0523,Hp0524, Hp0525,
Hp0526, Hp0527, Hp0528, Hp0529, Hp0531, Hp0532, Hp0533, Hp0534. Then by using
Clustal W software multiple sequence alignment is done. From the alignment we get
conserved genes region that analysed by Motif software such as “FMM”. By analysing this
helps to understand the molecular bases of infection and pathogenesis which can further
used to design novel drugsto prevent the infection. Drugs such as acetazolamide and
methazolamide and enzymes which plays a centrol role in H.pylori are Urease and
carbonic analysic which inhibit the growth of bacteria and decrease itspathogenicity of
infection in human body.
Keywords : Type IV Secretion System, Multiple Sequence Alignment, Motif, Helicobacter
pylori
Study the effect of RPM on Synthesis of Diacetone alcohol &

mesityl oxide from acetone
Shrinivas Tejerao Mundkar
CGPIT, Uka Tarsadia University, Bardoli – 394350, Gujarat, India
The reaction was performed in a 300 ml glass batch reactor equipped with
temperature and speed monitoring facility. The desired quantities of acetone (i.e. 250
ml) and the catalyst were charged before the heating was started. The agitation was
started, typically after 5 min, when the desired reaction temperature was attained.
This time was considered as the zero reaction time. The samples were re-moved after
specific time intervals and were cooled through a coil immersed in chilled water to
prevent acetone evaporation during the sampling. Various experiments were carried
out to study the effect of RPM on the kinetics of the reaction.
99
Discovery of Tadalfil Analog as a selective Antimalarial Agent

Vaishali patel, Satyanarayana Battula*
Tadalafil is a human PDE5 inhibitor for ED, PAH and BPH. Plasmodium falciparum PDEs
(pfPDEs) display a significant role in the cell cycle of Plasmodium falciparum growth.
Both the catalytic sites of PfPDEs and hPDE5 display only 41-47% sequence homology.
So as to this, it has been studied for the therapeutic utility as an antimalarial agent. The
structure activity relationship supports the hypothesis that the developed compounds
kill the parasite via inhibition of plasmodial PDE activity. It also proves that these
derivatives (Series 1 and 2) inhibit the hydrolysis of cyclic nucleotides of the parasite,
validating the cAMP/cGMP pathways as therapeutic targets against Plasmodium
falciparum.
Synthesis, Characterization and Biological Evaluation of some

novel Isoxazole derivatives
Vishvajit Raj
Sheth M N Science college, North Gujarat University, Patan.
The novel chalcones (3a-e and 4a-e) were prepared by aldol condensation of various 5-
aryl-2-furancarboxaldehyde (1a-e) respectively with acetophenone(2a) and 2-acetyl
naphthalene(2b). Both the series of chalcones (3a-e and 4a-e) were then treated with
hydroxylamine hydrochloride and obtained as iso oxazole (5a-e and 6a-e) heterocyclic
compounds. All the derivatives were characterized by IR, NMR and LC-MS spectral
features. The elemental content of all the compounds also determined. The
antimicrobial activities of all the iso oxazole derivatives was evaluated against common
microbes.
100
Catalytic Asymmetric Synthesis of Allylic Alcohols and Derivatives

and Their Applications in Organic Synthesis
Yash V Patel, Preksha N Vadukiya and Paresh N Patel*
Allylic alcohols represent an important and highly versatile class of chiral building blocks
for organic synthesis. We have synthesised several allylic alcohols by catalytic reduction
of chalcones. All the prepared compounds were characterised by NMR, HRMS, IR and UV
spectroscopy. This abstract of poster presentation summarizes the methods developed
for the catalytic asymmetric synthesis of enantioenriched allylic alcohols. These include:
dynamic kinetic resolution (DKR/DKAT), nucleophilic 1,2-addition to carbonyl groups,
allylic substitution, oxidation of C-H bonds, the addition of O nucleophiles to π systems,
reduction of unsaturated carbonyl compounds, and an alternative route from
enantioenriched propargylic alcohols. Furthermore, these catalytic asymmetric
processes have been exemplified by their applications in the syntheses of complex
molecules such as natural products and potential therapeutic agents. The review about
allylic alcohols and initial results of our work will be presented during the RSC-IW-SRSM
– 2019.
Reference: Alexandre Lumbroso, et. al., Angew. Chem. Int. Ed. 2013, 52, 2 – 45.
Structure elucidation of major degradant of venlafaxine

Tarapra Ankita, Vaghela Vipul
A.R. College of Pharmacy and G.H Patel Institute of Pharmacy
Venlafaxine, an antidepressant drug was subjected to hydrolytic stress condition in acidic
medium. The drug was found to be degraded under acid hydrolytic condition and
produce one major degradation product. The Rf of the degradation product was well
resolved from that of the pure drug. Isolation of degraded product was carried out by
performing preparative TLC using mobile phase n-Hexane: Ethyl acetate (7:3). Structural
elucidation of degradation product was done by IR, 1 H NMR and Mass spectrometric
studies. Its fragmentation pathway was proposed. The study presents isolation and
characterization of unidentified impurity in a drug product with the purpose of
identiﬁcation of the degradation products that could form during manufacturing, storage,
shipping, and in therapeutic use of a drug or its formulations for properly defining the
quality specification of product.
101
Study on synthesis and release kinetics of pH sensitive Cefixime

Loaded Lauryl Succinyl Chitosan Nanoparticles
Anand Patela, Jignesh Ravalb *, Preeti Bhalodiya a
aDepartment of Chemistry, UkaTarsadia University, Maliba Campus, Gopal Vidyanagar,
Bardoli-Mahuva Road, Tarsadia- 394 350, Tal: Mahuva, Dist: Surat, Gujarat, INDIA
bMandvi Science College(TMES), Mandvi, Dist: Surat, Gujarat, INDIA
The objective of the present study is to achieve Cefixime maximum therapeutic efficacy.
cefixime-loaded lauryl succinyl chitosan nanoparticles were prepared by water-in-oil-in-
water (w/o/w) double emulsion solvent evaporation technique with different
formulation variables such as concentrations of drug and polymer. The effects of these
variables on surface morphology, particle size distribution, encapsulation efficiency and
in vitro release behavior were examined. To observe the nature of nanoparticles, X-ray
diffraction studies were carried out. The release data obtained were determined using
various kinetic models and Korsmeyer–Peppas model showed an acceptable regression
value for all compositions. The in vitro drug release studies were carried out in various
buffer solutions (pH 1.2, 3.0, 5.0, 6.8, 7.4, 8.0, 1.2-7.4). The results showed marked
retardation of cefixime release and higher percentage of polymer gave longer drug
release profile. This may definitely provide a useful controlled-release drug therapy and
also prove to be effective over a long period of time.
Keywords: LSC, Cefixime, pH sensitive, Release kinetics
In-Vitro Anti-Bacterial Studies of Transition Metal-Chelate Complexes

Containing Fluoroquinolone Antibiotic Drug Mediated Schiff Bases
ANJALI V. DESAI, PARIMAL R. PATEL and SUTAPA MONDAL ROY
Fluoro-quinolones are a group of antibiotics that have been extensively used in treating
several bacterial diseases. These fluoroquinolone compounds have been synthesized
and are being used as antibacterials since 1962. They have antibacterial activity against
both gram-negative and gram-positive strains. The primary mechanism of their
antibacterial action is inhibition of the coiling of the long DNA chain into the restrained
space inside the bacterial cells. Compounds consisting of an azomethine group (with the
general structure R2 C=NR’) are known as Schiff bases. The immense chelating abilities,
of Schiff bases have attracted extreme attention in terms of analytical and biological
applications. In the present work, two drugs belong to fluoroquinolone group viz.
Ofloxacin and Ciprofloxacin were used to form Schiff bases. These antibiotic drugs-
derived Schiff bases were used as ligands and dissolved in methanol to react with
respective transition metal (CuCl2 ) salts. The resulting metal-chelate complexes were
characterized using UV-VIS spectroscopy, FTIR Spectroscopy, NMR Spectroscopy etc.
These chelate complexes show better antibacterial activity in terms of higher Zone-of-
Inhibition for both gram-negative and gram-positive bacteria.
102
Synthesis and Screening of Quinoline Analogues as Anti-

tubercular Agents
Kapupara Charvi, Thakkar Dinesh
A.R. College of Pharmacy and G.H Patel Institute of Pharmacy, S P University,
V V Nagar, Anand
Tuberculosis is deadly infectious disease caused by M. Tuberculi in human. It usually
attacks lung but can also affect other parts of body. In 2017, worldwide 10 million people
fell ill with TB. Among them 5.8 million are men, 3.2 million are women, 1.0 are million
children. So there is an emergence to develop new molecules for TB therapy. In the
present study various quinoline derivatives were designed taking quinoloine as a lead
molecule. All developed compounds were screened for in-vitro anti-TB activity using
Lewenstein Jenson (LJ) method on H37RV strain of M. tuberculosis. They exhibit
promising anti-TB activity at different concentration. Several Compounds of the designed
compounds were found to have potent anti-TB activity.
Preparation of alginate amide conjugate beads as a drug

delivery system
Jaymin H Parikha, Dharmesh R Chejara*a
aDepartment of Chemistry, Uka Tarsadia University, Bardoli, Gujarat, India –394350
Sodium alginate was chemically modified with four different amines of varying
hydrophilic hydrophobic characteristics (i.e. tris(hydroxymethyl)methyl-, allyl-,
benzyl- or pentyl-amines). Conjugation reaction was performed using carbodiimide
chemistry with the use of dicyclohexylcarbodiimide as a coupling agent. Synthesized
derivatives were characterized using proton NMR, infrared (IR) spectroscopy and
differential scanning calorimetry (DSC). These modified polymers were further used
to prepare beads loaded with folic acid as model drug, where it was tested in vitro to
assess their folic acid release profiles. The resulting beads accessed enteric release
kinetics, with tris(hydroxymethyl)methyl-amide alginic conjugate producing most
pronounced enteric profile. The results suggest the approach of developing such
chemically modified beads may have possibility of achieving some new drug delivery
systems for controlled drug release application.
Simple ultrasonic synthesis of nanoporous silica from sugar cane

leaf ash for the sustained release of drugs and removal of dyes
Meera C. Desai , Dr. Jyoti singh*
Department of Chemistry ,Uka Tarsadia University,Maliba campus , Gopal
vidhyanagar, Bardoli,Surat
In the present work, we have utilized the waste sugarcane leaf ash for the preparation of
Nanoporous silica .The obtained sugarcane leaves ash was treated with the acid followed
by alkali to make a transparent solution. The Gel was prepared from solution with the
treatment of acid. Nanoporous silica was obtained by adding the surfactant in the Gel,
and calcined the obtained product at 700° c. after calcinations of the obtained product
washed to get the pure nanoporous silica material. The nanoporous silica use for the
sustained release of drugs and removal of dyes. The synthesized particles characterized
by SEM,TEM,XRD.
103
Determination of order of reaction, reaction rate constant and

half-life of saponification of ethyl acetate
Kruti Gandhi*, Jaimini Gandhi, Hetal Patel
Maliba Pharmacy College, Gopal Vidyanagar Campus, Uka Tarsadia University, Surat-
394350, (Gujarat), India.
Saponification is the hydrolysis of a carboxylic acid ester in a basic medium. It is

essentially a soap manufacturing process that takes place by reacting the fatty acid with
alkali, especially triglycerides producing glycerol and carboxylate salts (soap).Order of
any chemical reaction can be determined by graphical, substitution and/or half-life
method. In chemical kinetics a reaction rate constant or reaction rate coefficient, k,
quantifies the rate of a chemical reaction. In this research, saponification of ethyl acetate
was performed in the presence of sodium hydroxide. 50 ml ethyl acetate and 50 ml
0.05N of sodium hydroxide were heated at 50°C and thoroughly mixed. At regular time
interval (0, 5, 10, 15, 20,25 and 30) minute 10 ml of each of the samples were withdrawn
into a conical flask having 10 g ice The sample was titrated against 0.05 N HCl solution
using phenolphthalein as an indicator. Order of reaction was determined by graphical as
well as substitution method. Reaction of ethyl acetate with sodium hydroxide followed
second order reaction meaning doubling the concentration of reactant will quadruple
the rate of the reaction. The reaction rate constant, half-life was foundto be 1.16Conc.-1
min-1 , 31.92 min respectively. Order of reaction, reaction rate constant, half-life of
saponification of ethyl acetate was successfully determined by graphical as well as
substitution method.
Validated spectrophotometric method for simultaneous estimation

of loratadine and betamethasone in synthetic mixture
Mrs. Bhoomi H. Patel*, Dr. Satish A. Patel
Shree S. K. Patel College of Pharmaceutical Education & Research, Ganpat
Vidyanagar,Mehsana-384012
A simple, accurate, rapid and precise spectrophotometric method has been developed for
simultaneous estimation of Loratadine and Betamethasone in synthetic mixture. This method
was based on UV spectrophotometric determination of two drugs, using First order derivative
method. Loratadine and Betamethasone were scanned separately in the wavelength range of
200-400 nm. From the overlay derivatised spectra of two drugs, it is evident that Loratadine
and Betamethasone show a zero crossing point at 239.2 nm and 247.2 nm. These two
wavelengths were employed for the determination of Loratadine and Betamethasone. The
method showed good reproducibility and recovery with % RSD less than 2. Method was found
to be rapid, specific, precise and accurate, can be successfully applied for the routine analysis
of Loratadine and Betamethasone in synthetic mixture, and combined dosage form without
any interference by the excipients. The method was validated according to ICH guidelines.
104
Spectrophotometric methods for simultaneous estimation of

febuxostat and diacerein in synthetic mixture
Ms.Roshani A. Patel*, Dr. Dipti B. Patel, Mr. Sachin A. Patel
Shree S. K. Patel College of Pharmaceutical Education & Research, Ganpat
Vidyanagar, Mehsana-384012
Present research work describes a Simple, Precise, Accurate, Fast and Economical two
Spectrophotometric methods for simultaneous estimation ofFebuxostat (FEB) and
Diacerein(DIA) in Synthetic Mixture. Method A is first order derivative spectrophotometric
method, in which261.4nm (Zero crossing point for FEB) was used for DIA and 295.1nm (Zero
crossing point for DIA) was used for FEB. Method B is area under curve (AUC), in the
wavelength range of 309.2-319.2nm for FEB and 251.1 -261.1 nm for DIA. Linearity for
detector response was observed in the concentration range of 2-12μg/ml for FEB and DIA by
both the methods. For Method A accuracy was assessed by %recovery studies and was found
to be 100.69 ±0.86 % and 101.99 ±0.81 % for FEB and DIA respectively. For Method B
accuracy was assessed by %recovery studies and was found to be 101.98 ± 0.49 % and 100.98
± 0.80 % for FEB and DIA respectively.The developed method was validated with respect to
Linearity, Accuracy (%recovery), Precision, LOD, LOQ and Assay. The results were validated
statistically as per ICH Q2 R1 guideline and were found to be satisfactory. The proposed
methods were successfully applied for the determination of for FEB and DIA in combination.
In-Vitro Anti-Bacterial Studies of Transition Metal-Chelate Complexes

Containing Ciprofloxacin-Imine and Levofloxacin-Imine Derivatives
SHREYA H. PATEL, BINAL T. AHIR, NIMESH I. PATEL and SUTAPA MONDAL ROY*
Department of Chemistry, Uka Tarsadia University, Maliba Campus, Gopal Vidhyanagar,
Bardoli 394350, Gujarat.
Ciprofloxacin and Levofloxacin are synthetic broad spectrum fluoroquinolone antibiotic

drugs. Both of these drugs binds to and inhibits the bacterial DNA gyrase, an enzyme
essential for DNA replication. This agent is more active against Gram-negative bacteria
than Gram-positive bacteria. Both of these drugs are antibiotics used to treat a number of
bacterial infections. Some new transition metal complexes, of drug-imines derived from
these two fluoroquinolones and p-substituted anilines, were synthesized and
characterized on the basis of physical properties, conductance measurements, elemental
analysis, UV/Vis., infrared and nuclear magnetic resonance spectroscopy. These ligands
as well as their metal complexes were also evaluated for their antibacterial activity
against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus,
Salmonella typhae, and E. coli. It was found that metal complexes are more antibacterial
as compared to uncomplexed ligands and bare drugs. The present study was carried out
in search of a target antibiotic instead of a broad spectrum one. Antibacterial activity of
the ligand and its metal complexes is compared with the standard drug ciprofloxacin and
levofloxacin. In this series Co (II) complexes showed high antibacterial activity and the
other complexes showed moderate antibacterial activity against different bacteria.
105
Synthesis of Ligands Based On S-Triazine Compounds and Their

Characterization and Anti-Microbial Activity
Vishal K. Mistry*1, Mahima R. Patel2, Dr P. J. Naik3, Bhavesh R. Sharma4

Department of Chemistry, Uka Tarsadia University, Bardoli
A variety of Schiff base ligands were synthesized from S-Triazine and Aldehyde via
conventional practice. Reaction was divided into four different stages to get desire
outcome. After complete synthesis of compound, Structures of these compounds were
confirmed by IR and NMR Spectral analysis. The novel synthesized compounds were
evaluated for antimicrobial activity against a diversity of bacterial strains and some of
this composite has shown significant antimicrobial activity.
Formulation and evaluation of herbal ointment from

Pseudarthria viscida whole plant extract
Kunal Naik, R. Krishnamurthy
CGBIBT, Uka Tarsadia University, Maliba Campus, Gopal Vidhyanagar, Bardoli
394350, Gujarat
Ayurveda- the traditional Indian medicine has illustrated herbal wealth of Indian
medicinal plants, as number of different plants and its extract and minerals shows anti-
aging as well as wound healing activities. Pseudarthria viscida is an important
constituent of herbal formulation Dashmoolarista. Whole plant is important and
consider for many ethnobotanical activities. The aim of this study is formulation and
physicochemical evaluation of ointment prepared from P. viscida plant extract. The
formulation of ointment was done under levigated condition by incorporating extract
with previously prepared jelly base. Thus prepared ointments was further evaluated for
its physicochemical parameter like color, odor, texture, viscosity, spreadability, pH,
Extrudability, diffusion study, loss on drying, solubility, washability and non-irritancy.
This ointment was also tested for stability under different temperature range and result
shows great stability as there were no changes in texture, spreadability, and diffusion
capacity of ointment. Thus, the formulations can be useful for different tropical
application as ointment. Evaluation of ethnobotanical potential of this ointment was
also done for normal and diabetic wound as well.
106
A Lawsone–DAMN based colorimetric Chemosensor for rapid naked-

eye detection of Mercury (II)
Mayank Gami, Divyang Panchal, Sharad Patil*
We designed and synthesized a new colorimetric chemosensor L based on the

combination of 3-hydroxy-1, 4-dioxo-1,4-dihydronaphthalene-2-carbaldehyde 2 and
diaminomaleonitrile 3 moieties. The recognition abilities of the probe with a range of
metal ions were evaluated and their optical properties have been systematically
investigated. Chemosensor L exhibited well defined naked-eye visible color changes
from yellow to pink for Hg2+ detection in acetonitrile. Other ions, including Na+ , Ca2+ ,
CO2+, Ni2+ , Cu2+, Mn2+ , Sn2+, Hg2+, Fe3+, and Th4+, had a negligible influence on the probe
behaviour. The limit of detection (LOD) was 1.1 X 10-7 M using the UV-vis changes. For
the selective recognition of Hg2+ ions, it forms a 1: 1 stoichiometric complex involving
naphthoquinone hydroxyl and diaminomaleonitrile nitrogen functionalities. The
complex formation was proposed to be in a 1 : 1 ratio based on Job’s plot, 1H NMR
titrations, ESI-mass spectrometry analysis and DFT calculations. Test strips based on L
were fabricated, which could act as convenient and efficient Hg2+ test kits. The results
consistently indicated that Lawsone–DAMN is an ideal sensor, which can be utilised to
monitor Hg2+ in solution over a wide pH range.
Decolourization of Methyl red using Calsium Hydroxide

and Ferrous sulphate
Dipa H. patel, Amrutlal Prajapat*
Chemistry, Department of Chemistry, UkaTarsadia University,
Bardoli – 394 350, Gujarat, India
Water effluents from textile industries are a major source of water pollution. This
waste streams contain numerous toxic dyes, which are harmful for aquatic life.
Therefore, there is a need to find economical and bio-friendly methods to degrade
textiles dyes. In this study, methyl red dye was used for degradation using ferrous
sulphate and calcium hydroxide as a flocculants. The oxidation and subsequent
degradation of the dye was found to be dependent on both, the amount of Fe+2 ions as
well as calcium hydroxide. A systematic study was carried out using 10 different sets
of methyl red solution with various doses of flocculants. Optimization of dose was also
studied and it has been found that the rate of degradation was enhanced with dose of
flocculants, whereas some had an inhibitory effect. The rates of degradation were
found to fit to first order kinetics. After the treatment of dye, analysis was studied
using UV-visible, conductometer and pH-meter.
107
Synthesis of 6-Aminophenanthridines via N2 Elimination Induced

Decarbonylative Cyclization Reaction in Benzotriazoles
Harshil S. Bhatt & Satyanarayana Battula*
Benzotriazole (BTA) has always been an interesting substrate due to its various roles
and modes in Chemical transformations and important applications in biology. For the
synthesis of 6 aminophenanthridine (6AP) an efficient functional group induced
strategy has been developed as a result of an in-situ generated novel system “CO−CH
(N1N2)”. This reaction includes a new method of N2 expulsion in benzotriazoles that
results in decarbonylative cyclization leading to the formation of 6AP. In this method,
easier and cheaply available substrates are used for the synthesis of 6AP. A new concept
is established in BTA which is based on ring-opening chemistry and successfully same
concept is applied for the generation of different secondary amine substituted
phenanthridines (6AP) from readily available substrates. Studies related to the
synthesis of various other heterocycles and its applications from these substrates are in
progress.
DMSO Assisted Synthesis of α-Ketoamide from 2-Oxo

Aldehyde and Secondary Amines
Nitesh Pareek, Siddhant Shah, and Dr. Satyanarayana Battula*

Chemistry, Department of Chemistry, UkaTarsadia University,
Bardoli – 394 350, Gujarat, India
Presenting an efficient synthesis of α-Ketoamide by the reaction between 2-

oxoaldehyde and amines in the presence of DMSO (Dimethyl sulfoxide) solvent under
metal free conditions. This involves the formation of 2-oxo iminium ion as an
intermediate which is the main feature of the reaction and produce α-Ketoamide by
the adequate nucleophilic attack of DMSO at C1 carbon atom.
108
Assessment of Total Hardness (TH) as an important parameter for

groundwater quality of Valsad district of South Gujarat
1Pruvesh Shroff, 2R. T. Vashi, *S. A. Desai

1, 2Navyug Science College, Surat, Gujarat, INDIA.
*B. M. College of Science & Technology, Bharthana - Vesu, Surat, Gujarat, INDIA.
The present investigation is carried out during 2007 to 2009 for the determination of
Total hardness (TH), Calcium (Ca) and magnesium (Mg) levels in groundwater samples
of Valsad district situated in South Gujarat, India. For the collection of water samples
fifteen sampling stations of the area were selected. Water samples shows TH level from
70 to 1060 mg/l with a mean value of 368 mg/l. The desirable limit of TH is 300 mg/l
and permissible limit is 600 mg/l as per IS standard. The lowest value of TH (70 mg/l)
was reported at S12 station (Sutharpada village) whereas the highest value of 1060
mg/l was recorded at S1 station (Tithal). The permissible limit for Calcium (Ca) is 200
mg/l and for Magnesium (Mg) is 90 mg/l as per IS standards. Water samples of
sampling stations of S1 (Tithal) and S2 (Dhamdachi) is not desirable for drinking
purpose as level of TH, Ca and Mg are beyond permissible limit.
Key words: Groundwater, Total Hardness (TH), Ca and Mg.
“A convenient, rapid and eco-friendly synthesis of

Chalcones N-[4-chloro-2-(2-fluorobenzoyl)phenyl]-3-
(substitutedphenyl)acrylamides as well as their
antimicrobial activity”
Dr. Nigam J. Desai* , Dr. Bhavnaben D. Mistry

*Department of Chemistry, Uka Tarsadia University, Bardoli.
Department of Chemistry, B.K.M.Sc.College, Valsad. (VNSGU)
In this work, an attempt was made to synthesize chalcones N-[4-chloro-2-(2-

fluorobenzoyl)phenyl]-3-(substitutedphenyl)acrylamide derivatives by the
condensation of aromatic aldehyde with N-[4-chloro-2-(2-
fluorobenzoyl)phenyl]acetamide under basic conditions by using both conventional
and microwave irradiation methods. A simple condensation of aromatic aldehyde and
N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide using sodium methoxide as a base
was carried out for the study. The synthesized compounds were characterized for IR,
1H NMR, 13C NMR and mass spectral analysis. It was observed that completion of a
reaction occurred in 10-12 min by microwave irradiation method and in 10-12 hr by
conventional method. Finally, it was observed that microwave irradiation method is
more convenient, rapid and eco-friendly as compare to conventional method. The
reaction time has been brought down from hours to seconds with improved yield as
compared to conventional method.
109
Depolymerization of guar gum using utlrasound

Amrutlal L. Prajapat
UTU, Bardoli
The present work investigates the application of ultrasound and microwave operated
individually or in combination for depolymerization of aqueous solution of guar gum. In
addition, intensification aspects due to the use of an initiator, potassium persulfate
(KPS), has been investigated. The extent of depolymerization has been analyzed in
terms of the reduction in intrinsic viscosity. Also, the effectiveness of treatment
approach has been analyzed on the basis of kinetic rate constant, limiting intrinsic
viscosity and the time required for the desired extent of viscosity reduction. The kinetic
rate constant has been found to increase with an increase in the temperature and KPS
loading. For the individual operation involving irradiations, the rate was found to be
higher in the case of ultrasound as compared to the microwave irradiations. In the case
of sequential approach, microwave followed by ultrasound was more effective as
compared to the approach of ultrasound followed by microwave. The obtained results
clearly established that ultrasound in combination with KPS was the most effective
approach for depolymerization. The work has also enabled to understand the effective
role of KPS and operating temperature in intensifying the viscosity reduction of guar
gum polysaccharides.
Decolorisation of dyes based on coagulation
Prakash Bhoraniya, Amratlal Prajapat

Department of Chemistry, Uka Tarsadia University, Bardoli.
Department of Chemistry, B.K.M.Sc.College, Valsad. (VNSGU)
Wastewaters from textile industries represent a source of water contamination, and

should be treated in some way so as to reduce the concentration of the polluting dyes,
prior to discharge of the wastewater to the receiving environment. In this study the
dye removal capacity of locally produced ferrous sulphate was investigated: The
efficiency of the process was investigated in series of batch experiments using
simulated textile dye solutions to assess the effects of various process parameters:
contact time, ferrous sulphate-lime(calcium hydroxide) weight ratio, coagulant dosage,
dye’s initial concentration, pH and reaction kinetics of coagulation. The result of the
study showed that an increase in both coagulant dosage and dye initial concentration
increases the percentage of dye removal. In all cases the percentage of dye removal at
optimized conditions is nearly or above 95%. Most of the reactions are completed in
less than 3 to 5 minutes. The highest percentage of the dye removal was observed at
pH around neutrality for all the dyes indicating that addition of lime(calcium
hydroxide) is indispensable to maintain efficient floc formation. It was found that
Ferroussulphatecombined with lime is suitable Material form removing dyes.
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Visit us on : http://utu.ac.in/dchemistry/index.html
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Organised by In Associaton with

Department of Chemistry Royal Society of Chemistry &

Department of Science & Technology

1. About Uka Tarsadia University 01

2. About RSC & NASI 03

3. About GSBTM and GOJCOST 04

5. About Department of Chemistry, UTU 13

7. Program Out Line 32

10. Poster Presentations 68

About Uka Tarsadia University

About Uka Tarsadia University

About Royal Society of Chemistry

About The National Academy of Sciences India

It gives me immense pleasure to hear that the Department of Chemistry in

I am pleased to extend my hearty welcome to all participants of “Royal Society of

Prof. Girjesh Govil

Chemistry is an ever growing specialized area in Applied Sciences, as it is a broad science

Dr. AJIT JOSHI

Be the 1 st in Chemistry through excellence in research & education to become Gujarat’s

Meet the state aspirations and objectives

Faculties and Staffs Students

Infrastructure, Facilities and Freedom

Pursuing world- Creating value

quality human including integrity, technology

resources to serve translational and creativity and development that

© Department of Chemistry, UTU 2019

Department of Chemistry Faculty Profile

“Dr Parth has completed his doctoral study from VNSGU. As a

“Dr Battula and his team is working on construction of

Department of Chemistry Faculty Profile

“Dr Paresh and his group is a team of professional chemists

“Dr Roy’s current and future research interests include studies

Department of Chemistry Faculty Profile

“Dr Dharmesh did his PhD (2014) from the Academy of

“Dr Jyoti’s research area is intensely focused on find out the

Dr Chintan did his Ph.D. (2013) from the Sardar Patel

Department of Chemistry Faculty Profile

Completed Doctoral degree in National Institute of Technology

Dr Jirimali is Contributing in the field of Bio-Nano-

Dr. Amrutlal Prajapat completed B.Sc. Chemistry

Department of Chemistry Faculty Profile

“Mr Bhavin is pursing his doctoral degree for this

“Dr Anand’s major research interest is in the area of drug

Department of Chemistry Faculty Profile

“Dr Pramod has completed his doctoral study from

“Dr Nilesh Pandya has done his doctoral study from

Mr. Dipen Desai

Department of Chemistry Faculty Profile

“Working in the field of Dyes Chemistry and also in

“Ms. Meghana has done her master with Physical

Ms. Shivani N. Tandel

Department of Chemistry at Glimpse

Dr. Sharad R. Patil, was honored to receive the

Senior Scientist Award had been awarded to

Dr. Rajamouli recived best poster presentation

Mr. Divyang Panchal and Ms. Preeti

Department of Chemistry at Glimpse

Ms. Preeti Bhalodiya, Ms. Nidhi Bhimani

Mr Chirag N Gadhiya Secured 58th Rank in CSIR-UGC-JRF, June – 2018.

Department of Chemistry at Glimpse

Dr. Rajamouli Boddula delivered a invited talk at

Dr Ajit Joshi, Dr Sharad Patil, Dr B

Dr. Sharad Patil has delivered a