TOPIC Notes

General
Autonomic Nervous system !!!!( especially the
receptors & drugs and their actions)
Gen Pharma ( Michaelis-Menten kinetics, Allosteric
agents/inhibitors etc., dose response curves)
General Patho ( Protooncogenes and tumor
suppressors, inflammation and healing)
Exercise physiology ( changes in RS,CVS, vasculature)
Cytochrome P450 inducers and inhibitors
Common toxicities
Action potential in cells and Neurons ( CVS also)
Paraneoplastic syndromes Pg 217

Biochemistry (ENTIRE!)
Molecular- Transcription/translation, RNA(m,t,r),
Splicing
Collagen synth and diseases
Lysosomal diseases and glycogen storage diseases
Cystic fibrosis
Metabolisms- GLUCOSE
FRUCTOSE
UREA
FOLIC acid
Fat metabolism and drugs! Do FA met, Ketone, Fasting/starvation state,
Apolipo+lipo, dyslipidemias and drugs
Nutrition – All Vits & def and Minerals (
hemochromatosis, Copper etc)

Immunology
HLA and the functions of T, B lympho, NK, inf etc.
Immune response
Hypersensitivity reactions
Transplant and GFVD
Auto antibodies
Immune deficiency states ( ESPLY Di-george, HIV,
CGD, SCID)
Immunosuppressants

Microbiology
Disinf and sterilization
STD !!!!
TORCH infections
Antimicrobials
Bact – staph, strep, diphtheria, Neisseria, clostridium,
TB, LYME, P.jirovecii
Virus- Hep B,E, HIV, polio, influenza, Coxsackie, Herpes
Fungi- C.albicans, apergillus
Parasites- common ones(ascaris, giardia etc.)
Public Health Sciences
Study designs and calculations
Inheritance pattern calculation
SD and Confidence interval
Probability calculation
Errors ( alpha and Beta)

Cardiology
Blood supply of heart
Cardiac physiology
Murmurs
MI/Angina/atherosclerosis
HF
RF/ BE/ Pericarditis
Cardio Pharm !! Do With ANS
1. Anti-lipid drugs (with biochemistry)
2. Anti-arrhythmics
3. Nitrates
4. Cardiac glycosides
5. CCB/ B-blocker

Endocrine
Thyroid
Diabetes and antidiabetic agents
MEN !
PTH, RANK-L stuff
Gastrointestinal
Regulation of GI function ( GI Physio)
Abdominal aorta + celiac trunk Pg 348-9
Portal Venous system Pg 350
Peptic ulcer disease
GI Histo !
Jaundice and all its causes
Liver stuff – Porta/ Cirrhosis/ Budd-chiari /CA/
Hepatitis
Liver enzymes
Colon CA
IBD, IBS
FAP

HematOnc
Formation of BCs
Porphyria
CO and Cyanide poisoning
Anemia
Porphyria
Leukemias
G6PD
Coagulation cascade + diseases + drugs Watch Rx360
Cell cycle with Chemotherapy + chemotoxman!!!! Watch Rx360
MSK
Muscle mechanics Watch Rx360 (4 videos)
UL and LL – Nerve, Artery and Vein
Cell biology of bone (Osteoblast and osteoclast Watch rx360
activity)
Osteoporosis, petrosis, LAB Values in bone disorders Watch Rx360
SLE !!!!!
MG/ Myopathies/ DMD etc.
Arachidonic acid pathway + Drugs
Bone tumours ( most common ones)
Dermat- Anat, Drug reactions, CA

CNS
Embryo- Neural crest/ notochord/ Neural tube defects
Regions of brain and functions
Spinal tracts
Ventricular system and its defects
Homunculus
STROKE- Regions/ territory and features
Intracranial Hemorrhage Pg 483
Multiple sclerosis
Seizures
Parkinson’s and other motor disorders
Alzheimer’s and dementia
ALS
GBS
Sleep physio
Speech stuff
CNS Tumors !

Psychiatry
Diagnosis of conditions based on timelines and Use the U world chart for timeline
features
PSYCH pharm!

Renal
Nephron Physio Pg555
Relative conc of solutes along PCT Pg 557, Look at the graph
Acid Base balance
CA
Nephrotic/ Nephritic Refer to the chart & pg 564
Renal Calculi
ATN / Acute interstitial necrosis
Diuretics !
ACE/ARB/ Direct renin inhibitors

Repro
Anat – M & F
Embryology- Pharyngeal pouches, Genito-urinary
Breast Pathology
STD!
Repro Physio ( M & F) `
Menstruation
Pregnancy – Prenatal tests( B-hcg, quadruple etc.)and
conditions
Childbirth and neonat – Infections
CA Ovary/endometrium

Respiratory
PHYSIO ( O2-Hb dissociation, Lung volumes, V/Q Glance through Kaplan
mismatch, Haldane & Bohr effect and Chloride shift)
Surfactant stuff, ARDS/NRDS
Pneumoconiosis
Resp loop graphs ( Obstructive vs Restrictive) See Kaplan
Resp parameter changes in diseases
Resp Pharm

Genetics
HOX genes
Population Genetics (Hardy Weinberg calc.)
Trisomies ( esply Downs)
Trinucleotide repeats
Muscle dystrophies