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Jaundice
Clinical Vignette
A 40-year-old patient has come to the outpatient clinic today because of jaundice.
Vital Signs
Temperature: 98.7 (37.0)
Blood Pressure: 130/70 mm
Hg Pulse: 98/min
Respirations: 18/min
Expected Tasks
The student’s teams should efficiently perform the following tasks during this lab:
Task Description
1
Read the following before the lab
1. Give examples for appropriate questions to identify the cardinal features of jaundice
(page 437)
Jaundice:
“How long have you been jaundiced?”
“Did the jaundice develop rapidly?”
“Is the jaundice associated with abdominal pain? Loss of appetite? Nausea? Vomiting?
Distaste for cigarettes?”
“Is the jaundice associated with chills? Fever? Itching? Weight loss?”
“In the past year have you had any transfusions? Tattooing?”
2
“Do you use any recreational drugs?” If yes, “Do you use any drugs intravenously?”
“Do you eat raw shellfish? Oysters?”
“Have you traveled abroad in the past year?” If yes, “Where? Were you aware that you
may have consumed unclean water?”
“Have you been jaundiced before?”
“Has your urine changed color since you noticed that you were jaundiced?”
“What is the color of your stools?”
“Do you have any friends or relations who are also jaundiced?”
“What type of work do you do? What other types of work have you done?”
“What are your hobbies?”
1
2. What are the different types of jaundice, how they can be differentiated according to history?
1
http://www.msdmanuals.com/professional/hepatic-and-biliary-disorders/approach-to-the-patient-with-liver-disease/jaundice
Intrahepatic Common: Alcoholic liver Gradual onset of jaundice
cholestasis disease, drugs, toxins, viral
hepatitis Pruritus
3. Explain how past medical, family history, and social history can be significant to patient
presenting with jaundice, give example from the textbook or the lecture.
Past medical history should identify known causative disorders, such as hepatobiliary
disease (eg, gallstones, hepatitis, cirrhosis); disorders that can cause hemolysis (eg,
hemoglobinopathy, G6PD deficiency); and disorders associated with liver or biliary disease,
including inflammatory bowel disease, infiltrative disorders (eg, amyloidosis, lymphoma,
sarcoidosis, TB), and HIV infection or AIDS.
Family history: should include questions about recurrent, mild jaundice in family
members and diagnosed hereditary liver disorders. The patient’s history of recreational
drug and alcohol use should be corroborated by friends or family members when possible.
Social History: should include questions about risk factors for hepatitis, amount and
duration of alcohol use, injection drug use, and sexual history.
4. What are the symptoms and signs of cirrhosis (page 465)
Features of Chronic Liver disease: ascites, asterixis, fetor hepaticus, muslce wasting,
Hepatobiliary gynecomastia, spider angiomas, palmar erythema, xanthelasmas or
diseases xanthomas, dupuytren’s contracture, parotid gland enlargement
Jaundice
Pruritus
Dark urine
Pale coloured stool
Steatorrhea
RUQ pain
Colicky pain
Teaching Points
Approach to a patient with jaundice
Identify possible risk factors for jaundice (drug use, STDs, etc)
Able to differentiate the type of jaundice based on the history and physical examination
Identify the signs of Liver failure
Sample of Patient (SOAP) Note
Abdominal System
SUBJECTIVE
CC: “I am having pain in my belly”
HPI :Maria, Female Patient reports pain in the right upper quadrant for 7 days. It is constant,
crampy and is 4/10 in severity with no radiation. Aggravated with pressure and no known alleviating
factors. Patient notes loss of appetite and yellowing of the skin. The patient’s urine is darker and
stools are pale. This morning, it was noticed that the right arm was itchy. No sick contacts but admits
to recent illness with fever, body aches and flu like symptoms that eventually resolved on its own. No
diarrhea or vomiting. No weight loss or fever
PMH: No significant PMH, advised by physician to monitor diet one year prior. No previous surgeries.
Up to date on preventive health screenings and immunizations.
Allergies: penicillin.
FH: Family is obese. Father Hypertensive. Mother had surgery to remove gall stones.
SH: Chef. Non-smoker. Alcohol use up to 3 drinks on occasion no more than once a month. No
recreational drug use. Recent travel to Trinidad 2 weeks ago. Admits to consuming local foods and
drinks. No exposure to pets. No tattoos.
ROS: No headache, dizziness, chest pain, palpitations, sore throat, burning on urination, changes in
gait, joint pain, rashes.
OBJECTIVE
GA: Patient is a middle aged woman/man of medium build, currently in mild painful distress. Alert
and oriented to time, place and person.