1st Year MBBS MCQs

1. The term “glycocalyx” refers to 6. The type of the blood cells which are likely to be
a. The negatively charge carbohydrate chains elevated in number in parasitic infection.
that protrude into the cytosol from a. Eosinophils
glycolipids and integral glycoprotiens b. Neutrophils
b. The negatively charged carbohydrate layer c. T lymphocytes
on outer cell surface d. B lymphocytes
c. The layer of anions aligned on the cytosolic e. Monocytes
surface of the plasma membrane 7. The clotting of blood in normal intact vascular
d. The large glycogen stores found in fast system is prevented by:
muscles a. Fibrinogen
e. A mechanism for cell-cell attachment b. Albumin
2. The Lysosomal enzymes are are mostly c. Platelets
a. Oxidases d. Thrombomodulin
b. Hydrolases e. Immunoglobulins
c. Reductases 8. Perforins are secreted by
d. Oxygenases a. Cytotoxic T cells
e. Lipases b. Macrophages
c. Plasma cells
3. A mother brought her 3 year old son to the clinic.
d. Platelets
He had watery stools fir the last one day. He is
e. Neutrophils
treated with a rehydration fluid containing glucose
and electrolytes. Which mechanism is most 9. A malnourished 60-years-old woman gets her
important in the absorption of this solution from complete blood count done for extreme weakness
the gastrointestinal tract? which showed her MCV is equal to 105fl (normal:
a. Passive diffusion 76-96), MCH is equal to 39 pg (normal:27-32).
b. Co-transport Which one of the following type of anemia does
c. Counter-transport she suffer from?
d. Secondary active transport a. Aplastic anemia.
e. Primary active transport b. Hemolytic anemia
c. Iron deficiency.
4. A 34 years old male after acute blood loss due to d. Megaloblastic anemia.
road side accident was brought to the emergency. e. Sickle cell anemia
In his peripheral blood film there was increased
10. The transfusion which will result in immediate
number of reticulocytes. What is it indicative of?
transfusion reaction is
a. Increased white cell turn over
a. Rh--- whole blood to an O Rh+
b. Decreased rate of RBC production
b. A Rh--- whole blood to B Rh+
c. Decreased rate or WBC production
c. AB Rh--- whole blood to an AB Rh+ patient
d. Increased rate of erythropoiesis
d. B Rh--- whole blood to a B Rh--- patient
e. Decreased in erythropoietin levels
e. A Rh--- whole blood to a A Rh--- patient
5. What is the cause of histamine release in allergic 11. On exposure of blood to collagen in the vessel
reaction? wall, clot formation is initiated by:
a. Binding of lgM to basophils a. Extrinsic pathway
b. Binding of lgE to most cells b. Intrinsic pathway
c. Release of histamine by helper T cells c. Both of the above
d. Free redical stimulation of endothelial cells d. Complement system
e. Binding of complement to most cells e. Negative feedback mechanism
12. Sodium potassium Pump
a. Is an example of secondary active transport
b. Does not require energy
c. Pumps two sodium ions outwards and there
potassium ion inward
d. Is an example of primary active transport
mechanism
e. Is not present in all body cell
13. Sustained contraction in muscle due to high
frequency stimulation would result in:
a. Single muscle twitch
b. Wave stimulation
c. Treppe
d. Tetanization
e. Muscle tone
14. Which of the following decreased in length during
the contraction of a skeletal muscle fiber?
a. Thin filaments
b. Thick filaments
c. Z discs of the Sarcomere
d. A band of the Sarcomere
e. I band of the Sarcomere
15. If a mixed nerve containing motor and sensory
fibers is cut, there is:
a. An increase in motor activity
b. An increase in sensory activity
c. Loss in sensation and motor activity
d. An increased in autonomic nervous system
activity
e. Formation of plaques on the myelin sheath
16. Secretory granules are mainly formed by
a. Golgi apparatus
b. Nucleus
c. Lysosomes
d. Mitochondria
e. Peroxisomes
17. The characteristic which is most important in
governing diffusion of a water insoluble substance
through the cell membrane is
a. Molecular weight
b. Electrical weight
c. Lipid Solubility
d. Diameter
e. Three dimension
18. Primary and secondary active transport both:
a. Generate ATP
b. Are based on passive movement of sodium
ions.
c. Include the passive movement of glucose
molecule
d. Use ATP directly
e. Move salutes against their concentration
gradients.
19. Skeletal muscle contraction is terminated by which
action:
a. Removal of acetylcholine from the
neuromuscular junction
b. Removal of CA+ from terminal of the
neuromuscular junction
c. Closure of the postsynaptic nicotinic
acetylcholine receptor
d. Removal of CA+ released by sarcoplasmic
reticulum
e. Return of the dihydropyridine receptor to
its resting conformation
20. Initiated of action potential in skeletal muscle by
stimulating its motor nerve:
a. Requires spatial facilitation
b. Requires temporal facilitation
c. Is inhibited by high concentration of
calcium at neuromuscular junction
d. Require the release of nor epinephrine
e. Require the release of acetylcholine