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Generic Name Brand Classification Dosage Mechanism of Indication Contraindication Side Effects Nursing

Name Action Implications


Metoclopramide Plasil GI stimulant/ Adults: - stimulates motility -relief of -allergy to Restlessnes,
Antiemetic/ Prevention of of upper GI tract symptoms of metoclopramide; drowsiness, -Obtain patient
Dopaminergic chemotherapy- without stimulating acute and GI hemorrhage, fatigue, history prior to
Blocker induced emesis gastric, biliary, or recurrent epilepsy, lactation, therapy,
insomnia,
- Dilute and give pancreatic secretions diabetic pregnancy including drug
by IV infusion gastroparesis EPS, transient hypersensitivitie
over at least 15 - appears to sensitize hypertension, s
min. Give first tissues to action of -prevention of nausea,
dose 30 min acetylcholine nausea and diarrhea -Inform patient
before vomiting of the potential
chemotherapy, - relaxes pyloric associated with adverse
repeat every 2 sphincter, which, emetogenic reactions, and
hours for two when combined with cancer encourage to
doses, then effects on motility, chemotherapy report any
every 3 hours accelerates gastric problems
for three doses. emptying and -single-dose
intestinal transit parenteral use:
Pedia: stimulation of -Monitor BP
Facilitation of - little effect on gastric emptying carefully during
intubation, gastric gallbladder or colon and intestinal IV
emptying motility transit of barium administration
- <6 yr: 0.1 when delayed
mg/kg by direct -increases LES emptying -Monitor
IV injection pressure interferes with diabetic patients,
over 1-2 min radiologic arrange for
- 6-14 yr: 2.5 to 5 -has sedative examination of alteration in
mg by direct IV properties and the stomach or insulin dose or
injection over induces release of intestine timing if
1-2 min prolactin diabetic control
is compromised
Vinblastine Velban Mitotic *Do not administer -Affects cell energy Palliative Allergy to Hypertension, -Ensure that
inhibitor more than once a production required treatment for vinblastine, malaise; patient is not
Antineoplastic week because of for mitosis and Hodgkin disease, leucopenia, acute weakness; pregnant before
leukopenic interferes with non-Hodgkin infection, administering
dizziness;
response nucleic acid lymphoma, pregnancy,
synthesis mycosis lactation numbness of -Do not
Pedia: fungoides, digits or administer IM or
1st wk; 2.5 mg/m2 -has antimitotic Letterer-Siwe paresthesia; subcutaneously
2nd wk: 3.75 effect and causes disease, loss of deep due to severe
3rd wk: 5 abnormal mitotic choriocarcinoma. tendon local reaction
4th wk: 6.25 figures. reflexes; and tissue
5th wk: 7.5 necrosis. Never

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