Label elements

of the CLP regulation

The CLP regulation

(Classification, Labelling
and Packaging of substances
and mixtures) institutes new hazard
symbols and standard phrases,
and new classification rules.
 Label elements of the CLP regulation 1

Physical hazards 1/2

Explosives
Classification Unstable Explosive Division 1.1 Division 1.2 Division 1.3 Division 1.4 Division 1.5 Division 1.6
Pictogram No pictogram No pictogram
is used is used

Signal word Danger Danger Danger Danger Warning Danger No signal word
Hazard statement H200 Unstable H201 Explosive; H202 Explosive; H203 Explosive; H204 Fire or H205 May mass No hazard
Explosive mass explosion severe projection fire, blast or projection hazard explode in fire statement
hazard hazard projection hazard

Flammable liquids Flammable solids

Classification Category 1 Category 2 Category 3 Classification Category 1 Category 2
Pictogram Pictogram

Signal word Danger Danger Warning Signal word Danger Warning

Hazard statement H224 Extremely H225 Highly H226 Flammable Hazard statement H228 Flammable H228 Flammable
flammable liquid flammable liquid liquid and vapour solid solid
and vapour and vapour

Flammable gases Flammable aerosols Oxidising gases

Classification Category 1 Category 2 Classification Category 1 Category 2 Classification Category 1

Pictogram No pictogram Pictogram Pictogram

Signal word Danger Warning Signal word Danger Warning Signal word Danger
Hazard statement H220 Extremely H221 Flammable Hazard statement H222 Extremely H223 Flammable Hazard statement H270 May cause
flammable gas gas flammable aerosol aerosol or intensify fire;
oxidizer

Oxidising liquids Oxidising solids

Classification Category 1 Category 2 Category 3 Classification Category 1 Category 2 Category 3
Pictogram Pictogram

Signal word Danger Danger Warning Signal word Danger Danger Warning
Hazard H271 May H272 May H272 May Hazard statement H271 May cause H272 May H272 May
statement cause fire or intensify fire; intensify fire; fire or explosion; intensify fire; intensify fire;
explosion; oxidiser oxidiser strong oxidiser oxidiser oxidiser
strong oxidiser
PRC – CNRS • Août 2012

1. CLP regulation: regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances
and mixtures, according to the last adaptation to technical and scientific progress.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Physical hazards 2/2

Self-reactive substances and mixtures Pyrophoric liquids

Classification Type A Type B Types C and D Types E and F Type G Classification Category 1
Pictogram There are no Pictogram
label elements
allocated to this
hazard category

Signal word Danger Danger Danger Warning Signal word Danger

Hazard H240 Heating H241 Heating may cause a H242 Heating H242 Heating Hazard H250 Catches fire
statement may cause an fire or explosion may cause a fire may cause a fire statement spontaneously if
explosion exposed to air

Pyrophoric solids Organic peroxides

Classification Category 1 Classification Type A Type B Types C and D Types E and F Type G
Pictogram Pictogram There are no
label elements
allocated to this
hazard category

Signal word Danger Signal word Danger Danger Danger Warning

Hazard H250 Catches fire Hazard H240 Heating H241 Heating may cause a H242 Heating H242 Heating
statement spontaneously if statement may cause an fire or explosion may cause a fire may cause a fire
exposed to air explosion

Substances and mixtures which, Self-heating

1. CLP regulation: regulation
in contact with water, emit flammable gases substances and mixtures
(EC) No 1272/2008 of the
Classification Category 1 Category 2 Category 3 Classification Category 1 Category 2 European Parliament and of
Pictogram Pictogram
the Council of 16 December
2008 on classification,
labelling and packaging of
substances and mixtures,
according to the last
Signal word Danger Danger Warning Signal word Danger Warning adaptation to technical and
scientific progress.
Hazard statement H260 In contact H261 In contact H261 In contact Hazard H251 Self- H252 Self-
with water with water with water statement heating: may heating in large
releases releases releases catch fire quantities: may
flammable gases flammable gases flammable gases catch fire
which may ignite
spontaneously

Substances and mixtures Gases under pressure

corrosive to metals Classification Compressed gas Liquefied gas Refrigerated Dissolved gas
Classification Category 1 liquefied gas

Pictogram Pictogram

Signal word Warning Signal word Warning Warning Warning Warning

Hazard statement H290 May be Hazard statement H280 Contains gas H280 Contains gas H281 Contains H280 Contains gas
corrosive to under pressure; under pressure; refrigerated under pressure;
may explode if may explode if gas; may cause may explode if
PRC – CNRS • Août 2012

metals
heated heated cryogenic burns heated
or injury

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Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
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 Label elements of the CLP regulation 1

Health hazards 1/2

Acute toxicity Specific target organ toxicity after single exposure

Classification Categories 1 and 2 Category 3 Category 4 Classification Category 1 Category 2 Category 3
Pictogram Pictogram

Signal word Danger Danger Warning Signal word Danger Warning Warning
Hazard statement : H300 Fatal if H301 Toxic if H302 Harmful if Hazard H370 Causes H371 May cause H335 May cause
oral swallowed swallowed swallowed statement damage to organs damage to organs respiratory irritation
(or state all organs (or state all organs or
affected, if known) affected, if known)
Hazard statement : H310 Fatal in H311 Toxic in H312 Harmful in H336 May cause
(state route of (state route of
dermal contact with skin contact with skin contact with skin exposure if it is exposure if it is drowsiness or
conclusively proven conclusively proven dizziness
Hazard statement : H330 Fatal if H331 Toxic if H332 Harmful if that no other routes that no other routes
inhalation inhaled inhaled inhaled of exposure cause of exposure cause
the hazard) the hazard)

Skin corrosion/irritation Serious eye damage/eye irritation

Classification Categories Category 2 Classification Category 1 Category 2
1A, 1B and 1C
Pictogram Pictogram

Signal word Danger Warning Signal word Danger Warning

Hazard H314 Causes H315 Causes skin Hazard H318 Causes H319 Causes
statement severe skin burns irritation statement serious eye serious eye
and eye damage damage irritation

Respiratory or skin sensitisation

Aspiration toxicity 1. CLP regulation: regulation
Classification Respiratory Skin sensitisation (EC) No 1272/2008 of the
sensitisation Category 1 and Classification Category 1 European Parliament and of
Category 1 and sub-categories the Council of 16 December
sub-categories 1A and 1B Pictogram
2008 on classification,
1A and 1B
labelling and packaging of
Pictogram substances and mixtures,
according to the last
Signal word Danger adaptation to technical and
scientific progress.
Hazard H304 May be fatal
Signal word Danger Warning statement if swallowed and
enters airways
Hazard H334 May cause H317 May cause
statement allergy or asthma an allergic skin
symptoms reaction
or breathing
difficulties if
inhaled
PRC – CNRS • Août 2012

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Health hazards 2/2

Specific target organ toxicity Carcinogenicity

after repeated exposure Classification Categories 1A Category 2
Classification Category 1 Category 2 and 1B

Pictogram Pictogram

Signal word Danger Warning Signal word Danger Warning

Hazard statement H372 Causes H373 May cause Hazard H350 May cause H351 Suspected
damage to organs damage to organs statement cancer (state of causing cancer
(or state all organs (or state all organs route of exposure (state route of
affected, if known) affected, if known) if it is conclusively exposure if it
through prolonged through prolonged proven that no is conclusively
or repeated or repeated other routes of proven that no
exposure (state exposure (state exposure cause other routes of
route of exposure route of exposure the hazard) exposure cause
if it is conclusively if it is conclusively the hazard)
proven that no other proven that no other
routes of exposure routes of exposure
cause the hazard) cause the hazard)

Germ cell mutagenicity Reproductive toxicity

Classification Categories 1A Category 2 Classification Categories 1A and 1B Category 2 Effects on or via
and 1B lactation
Pictogram Pictogram No pictogram
is used

Signal word Danger Warning Signal word Danger Warning No signal word
Hazard H340 May cause H341 Suspected Hazard H360 May damage H361 Suspected of H362 May cause
statement genetic defects of causing genetic statement fertility or the damaging fertility harm to breast-fed
(state route of defects (state unborn child (state or the unborn child children
exposure if it route of exposure specific effect if (state specific
is conclusively if it is conclusively known) (state route effect if known)
proven that no proven that no of exposure if it is (state route of
other routes of other routes of conclusively proven exposure if it is
exposure cause exposure cause that no other routes conclusively proven
the hazard) the hazard) of exposure cause that no other routes
the hazard) of exposure cause
the hazard)

1. CLP regulation: regulation

(EC) No 1272/2008 of the
European Parliament and of
the Council of 16 December
2008 on classification,
labelling and packaging of
substances and mixtures,
according to the last
adaptation to technical and
PRC – CNRS • Août 2012

scientific progress.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Environmental hazards
Hazardous to the aquatic environment

ACUTE CHRONIC
Classification Category 1 Category 1 Category 2 Category 3 Category 4
Pictogram No pictogram No pictogram
is used is used

Signal word Warning Warning No signal word No signal word No signal word
is used is used is used
Hazard statement H400 Very toxic to H410 Very toxic H411 Toxic to H412 Harmful H413 May cause
aquatic life to aquatic life aquatic life with to aquatic life long lasting
with long lasting long lasting with long lasting harmful effects to
effects effects effects aquatic life

Hazardous for the Ozone Layer 1. CLP regulation: regulation

(EC) No 1272/2008 of the
Pictogram European Parliament and of
the Council of 16 December
2008 on classification,
labelling and packaging of
substances and mixtures,
Signal word Danger
according to the last
Hazard statement H420 Harms public adaptation to technical and
health and the scientific progress.
environment by
destroying ozone
in the upper
atmosphere

OR

Hazardous for the Ozone Layer

Pictogram No pictogram
is used
Signal word Danger
Hazard statement EUH059 Hazardous
for the Ozone
Layer
PRC – CNRS • Août 2012

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Hazard statements
for physical hazards
Code Hazard statement
H200 Unstable explosive.
H201 Explosive; mass explosion hazard.
H202 Explosive; severe projection hazard.
H203 Explosive; fire, blast or projection hazard.
H204 Fire or projection hazard.
H205 May mass explode in fire.
H220 Extremely flammable gas.
H221 Flammable gas.
H222 Extremely flammable aerosol.
H223 Flammable aerosol.
H224 Extremely flammable liquid and vapour.
H225 Highly flammable liquid and vapour.
H226 Flammable liquid and vapour.
H228 Flammable solid.
H240 Heating may cause an explosion.
H241 Heating may cause a fire or explosion.
H242 Heating may cause a fire.
H250 Catches fire spontaneously if exposed to air.
H251 Self-heating: may catch fire.
H252 Self-heating in large quantities: may catch fire.
H260 In contact with water releases flammable gases which may ignite spontaneously.
H261 In contact with water releases flammable gas.
H270 May cause or intensify fire; oxidiser.
H271 May cause fire or explosion; strong oxidiser.
H272 May intensify fire; oxidiser.
H280 Contains gas under pressure; may explode if heated.
H281 Contains refrigerated gas; may cause cryogenic burns or injury.
H290 May be corrosive to metals.
PRC – CNRS • Août 2012

1. CLP legislation: Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and
mixtures, according to the last adaptation to technical and scientific progress.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Hazard statements
for health hazards
Code Hazard statement
H300 * Fatal if swallowed. * Combinaton
of these hazard
H301 ** Toxic if swallowed. statements is
H302 *** Harmful if swallowed. allowed.

H304 May be fatal if swallowed and enters airways. ** Combinaton

of these hazard
H310 * Fatal in contact with skin. statements is
H311 ** Toxic in contact with skin. allowed.

H312 *** Harmful in contact with skin. *** Combinaton

of these hazard
H314 Causes severe skin burns and eye damage. statements is
allowed.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H319 Causes serious eye irritation.
H330 * Fatal if inhaled.
H331 ** Toxic if inhaled.
H332 *** Harmful if inhaled.
H334 May cause allergy or asthma symptoms of breathing difficulties if inhaled.
H335 May cause respiratory irritation.
H336 May cause drowsiness or dizziness.
H340 May cause genetic defects (state route of exposure if it is conclusively proven that no other routes of exposure
cause the hazard).
H341 Suspected of causing genetic defects (state route of exposure if it is conclusively proven that no other routes
of exposure cause the hazard).
H350 May cause cancer (state route of exposure if it is conclusively proven that no other routes of exposure cause
the hazard).
H351 Suspected of causing cancer (state route of exposure if it is conclusively proven that no other routes of exposure
cause the hazard).
H360 May damage fertility or the unborn child (state specific effect if known) (state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard).
H361 Suspected of damaging fertility or the unborn child (state specific effect if known) (state route of exposure if it is
conclusively proven that no other routes of exposure cause the hazard).
H362 May cause harm to breast-fed children.
H370 Causes damage to organs (or state all organs affected, if known) (state route of exposure if it is conclusively proven
that no other routes of exposure cause the hazard).
H371 May cause damage to organs (or state all organs affected, if known) (state route of exposure if it is conclusively
proven that no other routes of exposure cause the hazard).
H372 Causes damage to organs (or state all organs affected, if known) through prolonged or repeated exposure (state
route of exposure if it is conclusively proven that no other routes of exposure cause the hazard).
H373 May cause damage to organs (or state all organs affected, if known) through prolonged or repeated exposure
(state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard).
PRC – CNRS • Août 2012

1. CLP legislation: Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and
mixtures, according to the last adaptation to technical and scientific progress.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
 Label elements of the CLP regulation 1

Hazard statements
for environmental hazards
Code Hazard statement
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
H411 Toxic to aquatic life with long lasting effects.
H412 Harmful to aquatic life with long lasting effects.
H413 May cause long lasting harmful effects to aquatic life.
H420 Harms public health and the environment by destroying ozone in the upper atmosphere.

Supplemental hazard information

Code Hazard statement
EUH001 Explosive when dry.
EUH006 Explosive with or without contact with air.
EUH014 Reacts violently with water.
EUH018 In use may form flammable/explosive vapour-air mixture.
EUH019 May form explosive peroxides.
EUH029 Contact with water liberates toxic gas.
EUH031 Contact with acids liberates toxic gas.
EUH032 Contact with acids liberates very toxic gas.
EUH044 Risk of explosion if heated under confinement.
EUH059 Hazardous to the ozone layer.
EUH066 Repeated exposure may cause skin dryness or cracking.
EUH070 Toxic by eye contact.
EUH071 Corrosive to the respiratory tract.
EUH201 Contains lead. Should not be used on surfaces liable to be chewed or sucked by children.
EUH201A Warning! Contains lead.
EUH202 Cyanoacrylate. Danger. Bonds skin and eyes in seconds. Keep out of the reach of children.
EUH203 Contains chromium (VI). May produce an allergic reaction.
EUH204 Contains isocyanates. May produce an allergic reaction.
EUH205 Contains epoxy constituents. May produce an allergic reaction.
EUH206 Warning! Do not use together with other products. May release dangerous gases (chlorine).
EUH207 Warning! Contains cadmium. Dangerous fumes are formed during use. See information supplied by
the manufacturer. Comply with the safety instructions.
EUH208 Contains (name of sensitising substance). May produce an allergic reaction.
EUH209 Can become highly flammable in use.
EUH209A Can become flammable in use.
EUH210 Safety data sheet available on request.
PRC – CNRS • Août 2012

EUH401 To avoid risks to human health and the environment, comply with the instructions for use.

1. CLP legislation: Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and
mixtures, according to the last adaptation to technical and scientific progress.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr
PRC
The Prevention of chemical risk unit is an intramural service
of the CNRS Institute of Chemistry. It provides a scientific
support to the CNRS and the chemical sector. The unit promotes
chemical safety and protection of human health against
dangerous chemicals.
The activities meet the needs of the scientific community,
occupational health and safety managers, public agencies,
industry and the general public.

Expert appraisal
The unit contributes to the expertise work at national and
european level for the toxicological and physico-chemical
evaluation of chemicals, and responds to requests from
government agencies, local authorities and entreprises.

Information
The multidisciplinary team responds to requests for information
related to the hazards of chemicals and their proper conditions
of use. It provides scientific support and implements
communication activities.

Training courses
The unit offers training courses in the field of chemical safety.
These courses are intended for users of chemicals, security
managers and occupational physicians. Several levels are
available, from risk awareness to proficiency courses.
Training courses may also be designed to map specific needs.

CNRS – PRC
Bâtiment 11 – Avenue de la Terrasse
91198 Gif-sur-Yvette cedex – France
www.prc.cnrs-gif.fr