GENERAL PRECAUTIONS
Large volume of refrigerated blood infused rapidly thru a central catheter into the
ventricle of the heart => cardiac dysrhythmias
Only Normal Saline solution (NSS) or 0.9% Sodium Chloride can be added to
blood components
To avoid risk of septicemia:
Infusion (1 unit) should not exceed 4 0
Blood admin set should be changed every 4-6 0 *
Always check the bag for expiration date: midnight on the day marked
Inspect bag for leaks, abnormal color, clots and bubbles
Blood must be admin asap (within 20-30 mins) from the blood bank, return if not
admin w/in that period
Recommended infusion rate:
quickly as client’s condition allows
varies w/ blood component being infused: few RBC and platelets =
infused rapidly = caution => circulatory overload
Assess VS and lung sounds:
before BT
after 1st 15 mins
every hour until 1 0 after BT is completed
CLIENT ASSESSMENT
Cultural and Religious beliefs (Jehova’s witness can’t have BT: eternal
consequences)
Ensure informed consent is obtained
Determine if there is previous history of BT reactions
Check VS, renal, circulatory, and respiratory status and ability to tolerate IV
admin
1
Temperature elevation may delay BT, notify physician (may mask symptom of
acute BT reaction)
ADMIN OF BT
Maintain standard, transmission-based, other precautions necessary
Insert IV line and infuse NS; maintain infusion at KVO rate
18- or 19- gauge check IV needle – maximum flow rate of blood products
(prevent damage of RBC); if smaller gauge, dilute RBC with NS
Central catheter is an acceptable venous access option
Always check the bag for volume of blood component
Blood products must be infused thru admin sets designed specifically for
blood; use Y tubing or straight tubing blood admin set w/ filter (designed to trap
fibrin clots and other debris that accumulate during blood storage).
Premedicate with Acetaminophen (Tylenol) or Diphenhydramine
(Benadryl) if w/ history of adverse rxns.
Oral = 30 mins before BT
IV = immediately before BT
Instruct client to report anything unusual immediately
Determine rate of infusion
Begin transfusion slowly under close supervision; no rxn noted on 1st 15
mins, flow rate can be increased
During BT, monitor for signs and symptoms for 1st 15 mins (most critical,
nurse must stay with the client)
Major ABO compatibility exists or severe allergic rxns occur = evident
st
w/in 1 50 mL of BT
Document client’s tolerance of BT
Monitor lab values and document effectiveness of treatment
REACTION TO BT
If reaction occurs:
1. Stop BT
2. Change IV tubing down to the IV site
3. Keep the IV line open w/ NS
4. Notify physician and blood bank
5. Return blood bag and tubing to blood bank
Do not leave client alone, monitor any life threatening symptoms
Obtain lab samples: blood or urine (free hemoglobin indicates RBC were
hemolyzed)
COMPLICATIONS OF BT
Transfusion reactions Disease transmission
Circulatory overload Hypocalcemia & Citrate intoxication
Septicemia Hyperkalemia
Iron overload
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5. Ask another RN or LPN to assist in confirming compatibility and identity
6. Assess VS and lung sounds before hanging solution