fibrosis /fi·bro·sis/ (fi-bro´sis) formation of fibrous tissue.

fibrot´ic

congenital hepatic fibrosis a developmental disorder of the liver marked by formation of irregular broad bands of fibr
ous tissue containingmultiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and port
al hypertension.
cystic fibrosis , cystic fibrosis of the pancreas a generalized hereditary disorder of infants, children, and young adu
lts, with widespreaddysfunction of exocrine glands, signs of chronic pulmonary disease, obstruction of pancreatic duct
s by eosinophilic concretions andconsequent pancreatic enzyme deficiency, and other symptoms.
endomyocardial fibrosis idiopathic myocardiopathy seen endemically in parts of Africa and less often in other areas,
characterized bycardiomegaly, thickening of the endocardium with dense, white fibrous tissue that often extends to in
volve the inner third or half of themyocardium, and congestive heart failure.
idiopathic pulmonary fibrosis chronic inflammation and progessive fibrosis of the pulmonary alveolar walls, with pro
gressive dyspnea andpotentially fatal lack of oxygen or right heart failure. The acute form is called Hamman-Rich
syndrome.
mediastinal fibrosis fibrous
mediastinitis; development of white, hard fibrous tissue in the upper portion of the mediastinum, sometimesobstructing
the air passages and large blood vessels.
nodular subepidermal fibrosis
1. benign fibrous histiocytoma.
2. a type of benign fibrous histiocytoma marked by subepidermal formation of fibrous nodules as a result of productive
inflammation.
pleural fibrosis fibrosis of the visceral pleura so that part or all of a lung becomes covered with a thick layer of nonex
pansible fibroustissue; fibrothorax is a more extensive form.

Dorland's Medical Dictionary for Health Consumers. © 2007 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

fi·bro·sis (f -br s s)
n.
The formation of fibrous tissue as a reparative or reactive process.

fi·brot ic (-br t k) adj.

The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights
reserved.

Fibrosis

Formation of fibrous tissue as a reaction or as a repair process; may occur due to treatment and/or disease. in lymphe
dema conditionknown as hardening of the limb with resulting restriction of circulatory flow, increased infection, and we
eping sores.

Mentioned in: Black Lung Disease, Bone Marrow Aspiration and Biopsy, Hypersensitivity
Pneumonitis, Lymphedema, Myelofibrosis,Pelvic Inflammatory Disease, Restrictive
Cardiomyopathy, Scleroderma, Silicosis

Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
fibrosis

[fībrō ′sis]

Etymology: L, fibra + Gk, osis, condition

1 a proliferation of fibrous connective tissue that occurs normally in the formation of scar tissue to replace tissue lost th
rough injury orinfection.

2 an abnormal condition in which fibrous connective tissue spreads over or replaces normal smooth muscle or other n
ormal organ tissue.Fibrosis is most common in the heart, lung, peritoneum, and kidney. See also cystic fibrosis, fibr
omyalgia.

Mosby's Medical Dictionary, 8th edition. © 2009, Elsevier.

fibrosis [fi-bro´sis]

formation of fibrous tissue; see also fibroid DEGENERATION. adj., adj fibrot´ic.

congenital hepatic fibrosis a developmental disorder of the liver, marked by formation of irregular broad band
s of fibrous tissue containingmultiple cysts formed by disordered terminal bile ducts, resulting in vascular co
nstriction and portal hypertension.

cystic fibrosis (cystic fibrosis of pancreas) see CYSTIC FIBROSIS.

diffuse idiopathic interstitial fibrosis (diffuse interstitial pulmonary fibrosis) idiopathic pulmonary fibrosis.

endomyocardial fibrosis an idiopathic type of MYOCARDIOPATHY that is endemic in various parts of Africa and ra
rely in other areas,characterized by CARDIOMEGALY, marked thickening of the endocardium with dense white fib
rous tissue that may extend to involve the innermyocardium, and by congestive HEART FAILURE.

idiopathic pulmonary fibrosis chronic inflammatory progressive fibrosis of the pulmonary alveolar walls, with
steadily progressivedyspnea, resulting in death from oxygen lack or right heart failure. Most cases are of unk
nown origin, although some are thought to resultfrom pneumoconiosis, hypersensitivity pneumonitis, sclerod
erma, and other diseases.

mediastinal fibrosis development of hard white fibrous tissue in the upper portion of the mediastinum, someti
mes obstructing the airpassages and large blood vessels; called also fibrosing or fibrous mediastinitis.

periureteral fibrosis retroperitoneal fibrosis.

pleural fibrosis fibrosis of the visceral pleura so that part or all of a lung becomes covered with a plaque or a t
hick layer of nonexpansiblefibrous tissue. The more extensive form is called FIBROTHORAX.
postfibrinous fibrosis that occurring in tissues in which fibrin has been deposited.

proliferative fibrosis that in which the fibrous elements continue to proliferate after the original causative fact
or has ceased to operate.

pulmonary fibrosis idiopathic pulmonary fibrosis.

retroperitoneal fibrosis deposition of fibrous tissue in the retroperitoneal space, producing vague abdominal
discomfort, and often causingblockage of the ureters, with resultant hydronephrosis and impaired renal functi
on, which may result in renal failure. Called also Ormond disease.

fibrosis u´teri a morbid condition characterized by overgrowth of the smooth muscle and increase in the colla
genous fibrous tissue of theuterus, producing a thickened, coarse, tough myometrium.

Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc.
All rights reserved.

fibrosis (fībrō´sis),

n 1. the process of forming fibrous tissue, usually by degeneration (e.g., fibrosis of the pulp). The process occ
urs normally in theformation of scar tissue to replace normal tissue lost through injury or infection.
2. an abnormal condition in which fibrous connective tissue spreads over or replaces normal smooth muscle
or other normal organtissue. Fibrosis is most common in the heart, lung, peritoneum, and kidney.

fibrosis, diffuse hereditary gingival,

n an uncommon form of severe gingival hyperplasia considered to be of genetic origin. The tissue is pink, fir
m, dense, and insensitiveand has little tendency to bleed.

fibrosis, hereditary gingival,

n an uncommon form of severe gingival hyperplasia that may begin with the eruption of the deciduous or per
manent teeth and ischaracterized by a firm, dense, pink gingival tissue with little tendency toward bleeding.

Mosby's Dental Dictionary, 2nd edition. © 2008 Elsevier, Inc. All rights reserved.

fibrosis

formation of fibrous tissue; fibroid degeneration.

postfibrinous fibrosis
that occurring in tissues in which fibrin has been previously deposited.
proliferative fibrosis
that in which the fibrous elements continue to proliferate after the original causative factor has ceased to oper
ate.
Saunders Comprehensive Veterinary Dictionary, 3 ed. © 2007 Elsevier, Inc. All rights reserved

fibrosis

Medtalk A proliferation of fibroblasts and fibrous tissue. See Bridging fibrosis, Hepatic fibrosis, Idiopathic inte
rstitial fibrosis of lung,Pipestem fibrosis, Radiation fibrosis, Stellate fibrosis, Systemic idiopathic fibrosis.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

fi·bro·sis (fī-brō'sis),

Formation of fibrous tissue as a reparative or reactive process, as opposed to formation of fibrous tissue as a
normal constituent of anorgan or tissue.

Farlex Partner Medical Dictionary © Farlex 2012

fi·bro·sis (fī-brō'sis)

Formation of fibrous tissue as a reparative or reactive process, as opposed to formation of fibrous tissue as a
normal constituent of anorgan or tissue.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

fi·bro·sis (fī-brō'sis)

Formation of fibrous tissue as a reparative or reactive process, as opposed to formation of fibrous tissue as a
normal constituent of anorgan or tissue.

Medical Dictionary for the Dental Professions © Farlex 2012