SUPPLEMENTAL HANDOUT

Page 1 , Left Lower Quadrant

MECHANISMS OF CELL INJURY

Page 2 , Left lower Quadrant

MECHANISMS OF CELL INJURY

Page 2 , Left Lower Quadrant

MECHANISMS THE PROMOTE & COUNTERACT
CELLULAR AGING

Page 3 , Left Lower Quadrant

TUBERCULOUS GRANULOMA

Page 5 , Left Lower Quadrant

Page 9, Right Lower Quadrant
OLIGOHYDRAMNIOS (POTTER) SEQUENCE

Page 23 , Left Upper Quadrant

Page 23 , Right Upper Quadrant
NATURAL HISTORY OF ATHEROSCLEROSIS

Page 28, Middle of the Page

Page 28 , Lower Part of Page
TYPES OF AORTIC DISSECTION

Page 29 , Left Upper Quadrant

DISSEMINATED INTRAVASCULAR
COAGULATION (DIC)

Page 43, Right Upper Quadrant

ARDS: MORPHOLOGY

Page 44, Right Upper Quadrant

Page 52, Right Lower Quadrant
DISEASES ASSOCIATED WITH H. PYLORI INFECTION
Page 53, Right Upper Quadrant
ULCER MORPHOLOGY

Page 54, Left Upper Quadrant

Page 54, Right Lower Quadrant
Page 57, Right Upper Quadrant
NATURAL HISTORY OF HBV

Page 57, Right Lower Quadrant

ALCOHOLIC LIVER DISEASE (ALD)

Page 58, Left Upper Quadrant

Page 58, Right Upper Quadrant
Page 61, Right Upper Quadrant
ACUTE TUBULAR INJURY/NECROSIS

Page 64, Left Lower Quadrant

 PYELONEPHRITIS

Page 64, Right Lower Quadrant

POLYCYSTIC KIDNEY DISEASE

Page 65, Right Lower Quadrant

OBSTRUCTIVE UROPATHY

Page 66, Right Upper Quadrant

 Papillomatous
growth

No atypia Atypia

Thick Mild, polarity Marked, polarity

Thin urothelium;
urothelium; and cohesion and cohesion (-
small
larger (+), few mitosis ), more mitosis

Papilloma PUNLMP* Low-grade UCA High-grade UCA

NON-INVASIVE PAPILLARY TUMORS: Morphology

Page 67, Right Lower Quadrant

 Testicular germ
cells

ITGCN*

Totipotential tumor
cells (embryonal
carcinoma)
Seminoma

Embryonic
Extraembryonic
tissue germ cell
layers

Yolk sac
Teratoma
tumor

Chorio-
carcinoma

Page 69, Left Upper Quadrant

Page 74, Left Upper Quadrant
CLINICAL PRESENTATIONS OF BREAST DISEASE

Page 75, Left Lower Quadrant

CLINICAL PRESENTATION OF BREAST CARCINOMA

Page 76, Left Upper Quadrant

 ↑Thyroid
hormones

Secondary
Primary (Thyroid
(Extrathyroid
pathology;↓TSH)
pathology; ↑TSH)

Diffuse Toxic
Hyperfunctional TSH-secreting
Hyperplasia Hyperfunctional
multinodular pituitary
(Graves disease) thyroid adenoma
Goiter adenoma
85%

HYPERTHYROIDISM

Page 78, Right Upper Quadrant

 ↓Thyroid
hormones

Primary (Thyroid
Secondary
pathology;
(Extrathyroid
↑TSH); more
pathology; ↓TSH)
common

Congenital
Iatrogenic Hypothalamic
(Iodine Autoimmune
(Surgery and and pituitary
deficiency*, (Hashimoto)**
Radiation failure
Genetic)

HYPOTHYROIDISM

Page 78, Right LowerQuadrant

 CLINICAL
MANIFESTATIONS OF DM

Page 81, Left Upper Quadrant

TUMOR PROGRESSION SEQUENCE OF MELANOMA

Page 83, Right lower Quadrant

 Ischemic Hemorrhagic

Hypertensive Intracranial Vascular

Global Focal
encephalopathy hemorrhage malformations

CEREBROVASCULAR DISEASES

Page 91, Left Lower Quadrant