EFEK IMUNOMODULATOR KOMBINASI EKSTRAK ETANOLIK HERBA MENIRAN (Phyllanthus niruri

Linn.), UMBI KELADI 47

TIKUS (Thyphonium flagelliforme (Lodd.) Blume), DAN DAUN SIRIH MERAH (Piper crocatum Ruiz.
&
Pav.) TERHADAP FAGOSITOSIS MAKROFAG TIKUS SECARA IN VITRO
VIVENNA KHORIS
Universitas Gadjah Mada, 2015 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR PUSTAKA

Abbas, A.K., Lichtman, A.H. & Pillai, S., 2007, Cellular and Molecular
Immunology, 6th Edition, 3-5, Elsevier Publisher, Philadelphia.

Abbas, A.K., Lichtman, A.H. & Pillai, S., 2012, Cellular and Molecular
Immunology, 7th Edition, 1-6, 55-58, Elsevier Publisher, Philadelphia.

Agarwal, S.S. & Singh, V.K., 1999, Immunomodulators : A Review of Studies on

Indian Medicinal Plants and Synthetic Peptides, PINSA, B65, 179-204.

Anonim, 2008, Keputusan Menteri Kesehatan Republik Indonesia Nomor

121/Menkes/SK/II/2008 tentang Standar Pelayanan Medik Herbal, Depkes
RI, Jakarta.

Anonima, 2014, Phyllanthus niruri, en.m.wikipedia.org/wiki.Phyllanthus_niruri,

11 Februari 2015.

Anonimb, 2014, Piper crocatum, www.plantsrescue.com/piper-crocatum/, 11

Februari 2015.

Apriyanto, S., 2011, Uji Aktivitias Imunomodulator Ekstrak Etanolik Daun Sirih
Merah (Piper crocatum Lamk) terhadap Proliferasi Sel Limfosit dan
Fagositosis Makrofag pada Tikus yang diinduksi Vaksin Hepatitis B,
Skripsi, Universitas Gadjah Mada, Yogyakarta.

Arifah, A.N. & Nurkhasanah, 2014, Efek Fraksi Etil Asetat Ekstrak Etanol Akar
Pasak Bumi (Eurycoma longifolia, Jack) terhadap Aktivitas Fagositosis
Makrofag secara In Vitro, Pharmaciana, 4(1), 9-14.

Backer, C.A. & Van Den Brick, R.C.B., 1963, Flora of Java, 167, 170, Published
under The auspices og the rijksherbarium, Leyden.

Backer, C.A. & Van Den Brick, R.C.B., 1965, Flora of Java, (Vol I), 165,
Groningen N.V.P. Noordhoff, Netherlands.

Backer, C.A. & Van Den Brick, R.C.B., 1968, Flora of Java (Spermatophyta
Only), (Vol III), 167, 170, Groningen N.V.P. Noordhoff, Netherlands.

Baratawidjaja, K.G., 2000, Imunologi Dasar, Edisi keempat, 1-2, 246, Balai
Penerbit FKUI, Jakarta.

Baratawidjaja, K.G. & Rengganis, I., 2012, Imunologi Dasar, Edisi X, 61-75,
524-529, Balai Penerbit Fakultas Kedokteran Universitas Indonesia,
Jakarta.
 EFEK IMUNOMODULATOR KOMBINASI EKSTRAK ETANOLIK HERBA MENIRAN (Phyllanthus niruri
Linn.), UMBI KELADI 48
TIKUS (Thyphonium flagelliforme (Lodd.) Blume), DAN DAUN SIRIH MERAH (Piper crocatum Ruiz.
&
Pav.) TERHADAP FAGOSITOSIS MAKROFAG TIKUS SECARA IN VITRO
VIVENNA KHORIS
Universitas Gadjah Mada, 2015 | Diunduh dari http://etd.repository.ugm.ac.id/

Choo, C.Y., Chan, K.L., Sam, T.W., Hitotsuyanagi, Y. & Takeya K., 2001, The
Cytotoxic and Chemical Constituents of The Hexane Fraction of
Typhonium flagelliforme (Araceae), Journal of Ethnopharmacology,
77(1), 129-31.

Chandra, P., 2015, Wawancara atau komunikasi pribadi dengan penulis, 20 Maret
2015.

Comalada, M., Ballester, I., Bailon, E., Sierra, S., Xaus, J., Galvez, J., Sanchez de
Medina, F. & Zarzuelo, A., 2006, Inhibition of Proinflammatory Markers
in Primary Bone Marrow-derived Mouse Macrophages by Naturally
Occuring Flavonoids : Analysis of the Structure-activity Relationship,
Biochemical Pharmacology, 72, 1010-1021.

Erviana, R., Purwono, S. & Mustofa, 2011, Active Compunds Isolated from Red
Betes (Piper crocatum Ruiz & Pav) leaves Active Against Streptococcus
mutans through its Inhibition Effect on Glucosyltransferase Activity, J
Med Sci, 43(2), 71-78.

Harfia, M. & Lucie, W., 2009, Uji Aktivitas Ekstrak Etanol 50% Umbi Keladi
Tikus (Typhonium flagelliforme (Lodd) Bl) terhadap Sel Kanker Payudara
(MCF-7) secara In Vitro, Media Litbang Kesehatan, XIX(1).

Hartini, Y.S., Wahyuono, S., Widyarini, S. & Yuswanto, 2014, In Vivo

Immunomodulatory Effect and Histopathological Features of Mouse Liver
and Kidney Treated with Neolignans Isolated from Red Betel (Piper
crocatum Ruiz & Pav) Leaf, Tropical Journal of Pharmaceutical
Research, 13(10), 1609-1614.

Hay, F.C. & Westwood, O.M.R., 2002, Practical Immunology, Fourth Edition,
179-180, 203-206, Blackwell Science Ltd, UK.

Jensch-Junior, B.E., Pressinotti, L.N., Borges, J.C.S. & Silva, J.R.M.C., 2006,
Characterization of Macrophage Phagocytosis of the Tropical Fish
Prochilodus scrofa (Steindachner, 1881), Aquaculture, 251, 509-515

Kamboj, V.P., 2000, Herbal Medicine, Current Science, 78(1).

Kustiawan, P.M., 2012, Isolasi dan Identifikasi Senyawa Imunostimulan Non

Spesifik In Vitro dari Daun Sirih Merah (Piper crocatum Ruiz. & Pav.),
Tesis, Fakultas Farmasi UGM, Yogyakarta.

Lai, Choon-Sheen, Rosemal, H.M.H., Nair, N.K., Mansor, S.M. & Navaratnam,
V., 2010, Chemical constituents and Invitro Anticancer Activity of
Typhonium flagelliforme (Araceae), Elsevier Ireland Ltd, 127, 486-494.
 EFEK IMUNOMODULATOR KOMBINASI EKSTRAK ETANOLIK HERBA MENIRAN (Phyllanthus niruri
Linn.), UMBI KELADI 49
TIKUS (Thyphonium flagelliforme (Lodd.) Blume), DAN DAUN SIRIH MERAH (Piper crocatum Ruiz.
&
Pav.) TERHADAP FAGOSITOSIS MAKROFAG TIKUS SECARA IN VITRO
VIVENNA KHORIS
Universitas Gadjah Mada, 2015 | Diunduh dari http://etd.repository.ugm.ac.id/

Mankaran, S., Dinesh, K., Deepak, S. & Gurmeet, S., 2013, Typhonium
flagelliforme : A Multipurpose Plant, review article, International
Research Journal of Pharmacy, 4 (3).

Middleton, E., Kandaswami, C. & Theoharides, T.C., 2000, The Effects of Plant
Flavonoids on Mamalian Cells : Implications for Inflammation, Heart
Disease, and Cancer, Pharmacol Rev, 52(4), 673-751.

Murwanti, R., 2014, Pengembangan Produk Herbal Unggulan Berbasis Kearifan

Lokal Gama Imun dan Gama Live, Sebagai Obat Herbal Terstandar
(OHT) Imunomodulator dan Hepatoprotektif, Laporan Kemajuan
Kegiatan Penelitian Unggulan Perguruan Tinggi, Universitas Gadjah
Mada, Yogyakarta.

Nugroho, Y.A., 2011, Efek Pemberian Kombinasi Buah Sirih (Piper betle L)
Fruit, Daun Miyana (Plecranthus scutellarioides (L.) R. BR.) Leaf, Madu
dan Kuning Telur terhadap Peningkatan Aktivitas dan Kapasitas
Fagositosis Sel Makrofag, artikel, Media Litbang Kesehatan, 22 (1).

Nworu, C.S., Akah, P.A., Prksch, P. & Esimone, C.O., 2010, The Effects of
Phyllanthus niruri aqueous extract on the Activation of Murine
Lymphocytes and Bone Marrow-derived macrophage, Immunol Invest,
39(3), 245-67

Nurrochmad, A., Ikawati, M., Sari, I.P., Murwanti, R. & Nugroho, A.E., 2015,
Immunomodulatory Effects of Ethanolic Extract of Thyphonium
flagelliforme (Lodd.) Blume in Rats Induced by Cyclophosphamide,
Journal of Evidence-Based Complementary & Alternative Medicine, 1-6

Owen, J.A., Punt, J., Stranford, S.A. & Jones, P.P., 2013, Kuby Immunology,
Seventh Edition, 147-152, W. H. Freeman and Company, New York.

Paithankar, V.V., Raut, K.S., Charde, R.M. & Vyas, J.V., 2011, Phyllanthus
niruri: A Magic Herb, review artikel, Research in Pharmacy, 1 (4), 1-9

Roitt, I.M., Delves, P.J., Martin, S.J. & Burton, D.R., 2006, Roitt’s Essential
Immunology, Eleventh Edition, 2-4, Blackwell Publishing Ltd, UK.

Sagala, R.J., 2013, Uji Imunomodulator Kombinasi Ekstrak Etanolik Herba

Meniran (Phyllanthus niruri Linn.), Umbi Keladi TIkus (Thyphonium
flagelliforme) Lodd.)Blume, dan Daun Sirih Merah (Piper crocatum)
terhadap Fagositosis Makrofag secara In Vitro, Skripsi, Fakultas Farmasi
UGM.

Sarmoko dan Cahyani, F.M., 2014, Keladi Tikus (Typhonium flagelliforme (Lodd)
Bl), ccrc.farmasi.ugm.ac.id, 29 November 2014.
 EFEK IMUNOMODULATOR KOMBINASI EKSTRAK ETANOLIK HERBA MENIRAN (Phyllanthus niruri
Linn.), UMBI KELADI 50
TIKUS (Thyphonium flagelliforme (Lodd.) Blume), DAN DAUN SIRIH MERAH (Piper crocatum Ruiz.
&
Pav.) TERHADAP FAGOSITOSIS MAKROFAG TIKUS SECARA IN VITRO
VIVENNA KHORIS
Universitas Gadjah Mada, 2015 | Diunduh dari http://etd.repository.ugm.ac.id/

Sriyanti, N.K.D., 2012, Efek Imunomodulator Ekstrak Etanol Umbi Keladi Tikus
(Thyphonium flagelliforme (Lodd.) Blume) terhadap Kemampuan
Fagositosis Makrofag pada Tikus Terinduksi Cyclophosphamide, Skripsi,
Fakultas Farmasi UGM, Yogyakarta.

Sudewo, B., 2007, Basmi Penyakit dengan Sirih Merah cit. Erviana, R., Purwono,
S. & Mustofa, 2011, Active Compunds Isolated from Red Betel (Piper
crocatum Ruiz & Pav) leaves Active Against Streptococcus mutans
through its Inhibition Effect on Glucosyltransferase Activity, J Med Sci,
43(2), 71-78.

Sheehan, C., 1997, Clinical Immunology Principles and Laboratory Diagnosis,

Second Edition, 148, Lippincott Company, Philadelphia.

Sunarno, 2009, Pengaruh Meniran (Phyllanthus niruri L) Terhadap Patogenesis

Infeksi Salmonella, Jurnal Kefarmasian Indo, 1, 71-76.

Syahid, S.F., 2008, Keragaman Morfologi, Pertumbuhan, Produksi, Mutu, dan

Fitokimia Keladi Tikus (Thyphonium flagelliforme (Lodd.) Blume) Asal
Variasi Somaklonal, Jurnal Littri, 14 (3), 113-118.

Taylor, L., 2003, Technical Data Report for Chanca Piedra “Stone Breaker”
(Phyllanthus niruri), Sage Press, Inc., Austin.

USDA, 2008, Plants Database, http://plants.usda.gov, 30 November 2014.

WHO, 2007, Guidelines for Assessing Quality of Herbal Medicineswith Reference

to Contaminant and Residues, 1-5, WHO Press, Geneva.

Wang, C., Yu, X., Cao, Q., Wang, Y., Zheng, Guoping, Tan, Thian Kui, Zhao, H.,
Zhao, Y., Wang, Yiping & Harris, D.C.H., 2013, Characterization of
Murine Macrophages from Bone Marrow, Spleen, and Peritoneum, BMC
Immunology, 14, 6

Zalizar, L., 2013, Flavonoids of Phylanthus niruri as Immunomodulators A

Prospect to Animal Disease Control, ARPN Journal of Science and
Technology, 3(5), 529-532

Zhang, X., Goncalves, R. & Mosser, D.M., 2008, The Isolation and
Charaterization of Murine Macrophages, Current Protocol Immunology,
14, 1-18