BIOFARMASI

“Biofarmasi dari sediaan Transdermal”

Dosen :

Prof. Teti Indrawati, M.Si., Apt.

Disusun oleh :

Diah Puspita Sari (16334018)

Anis Nindi Hasianavita (16334023)

PROGRAM STUDI FARMASI

FAKULTAS FARMASI P2K
INSTITUT SAINS DAN TEKNOLOGI NASIONAL
JAKARTA
2018
 DAFTAR ISI

KATA PENGANTAR ............................................................................................. 1

BAB I
PENDAHULUAN ....................................................................................................................2
1.1 Latar Belakang ..........................................................................................................2

1.2 Rumusan Masalah .....................................................................................................3

1.3 Tujuan ........................................................................................................................3

BAB II
TINJAUAN PUSTAKA ...........................................................................................................4
2.1 Anatomi dan Fisiologi Kulit ......................................................................................4
2.2 Transdermal Drug Delivery System (TDDS) ............................................................7
2.2.1 Definisi Transdermal Drug Delivery System (TDDS) ....................................7
2.2.2 Jenis Transdermal Patch ...................................................................................9
2.2.3 Keuntungan dan Kerugian Transdermal Drug Delivery System (TDDS) .....11
2.3 Faktor yang mempengaruhi Transdermal Delivery.................................................12
2.4 Kulit dan Absorpsi perkutan ...................................................................................14
2.5 Pengahantaran Obat secara Transdermal ................................................................15
2.6 Jalur Permeasi Transdermal ....................................................................................17
2.7 Mekanisme Biofarmasi Transdermal Drug Delivery System .................................17
2.8 Sediaan Transdermal ..............................................................................................18
2.9 Contoh Obat Transdermal DDS ..............................................................................19
2.10 Obat Konvensional Sediaan Topikal ......................................................................20

BAB III
PEMBAHASAN ....................................................................................................................21

BAB IV
KESIMPULAN DAN SARAN ..............................................................................................23
4.1 Kesimpulan ..............................................................................................................23
4.2 Saran .........................................................................................................................24
DAFTAR PUSTAKA .............................................................................................25
LAMPIRAN JURNAL .......................................................................................... 26