CELL THEORY Cytoplasm Protoplasm 1. Cell is the basic unit of life. (Robert Hooke , who made use consists of cytosol, consists of cytoplasm, of the term “cell” to describe the cork cells reminding him of organelles and inclusions nucleus and cellular the small rooms that monks lived in) membrane. Cytosol of cytoplasm Protoplasm is considered as 2. All living things are made of cells ( Matthias Schleiden, consists of water, salts and the living substance inside botanist. All plants are made of cells; Theodore Schwann, all organic molecules. the cell. It is a complex, animals are made of cells) Organelles are the tiny translucent substance 3. Cells come from pre-existing cells (Rudolf Virchow, cells organ like structures which is semi-fluid in undergo cell division) present within a cell with consistency and composed Modern Cell Theory: predefined and specific mainly of nucleic acids, functions. Inclusions are proteins, lipids, 4. The cell contains hereditary information(DNA) which is insoluble particles present carbohydrates and passed on from cell to cell during cell division. in the cytoplasm. inorganic salts. 5. All cells are basically the same in chemical composition and metabolic activities. Cytosol is the part of the cytoplasm that does not contain 6. All basic chemical & physiological functions are carried out organelles inside the cells. 7. Cell activity depends on the activities of sub-cellular structures within the cell REMEMBER : In the organisms which have the presence of a nucleus, the protoplasm surrounding the nucleus is termed Anton Van Leeuwenhoek – 1st to observe a live organism as cytoplasm. All the contents of the cell are considered in the which he called “animacules” cytoplasm in prokaryotes (organisms lacking nucleus) whereas MAIN PARTS OF THE CELL: in the eukaryote organisms the cellular contents present in the nucleus are differentiated from the cytoplasm by a definite 1. Cell Membrane nuclear membrane. The contents present within the nucleus 2. Cytoplasm are called as nucleoplasm. 3. Nucleus ● NUCLEUS – brain of the cell; control center; contain the CELL PARTS AND FUNCTIONS genetic material(DNA); protected or enclosed ● CELL MEMBRANE – outermost covering; bilipid; by the nuclear membrane; large oval, may semipermeable; made primarily of lipids and contain 1 or more nucleoli; cytoplasm surrounding proteins; selectively permeable; FLUID MOSAIC the nucleus is called KARYOPLASM/NUCLEOPLASM MODEL covered by a nuclear membrane with tiny holes Structure: called nuclear pore A. LIPID BILAYER STRUCTURE: a. PHOSPHOLIPIDS – forms the hydrophobic (water - consist of NUCLEOLUS (little nucleus) who's repelling) and hydrophilic (water loving) part function is to produce protein (RNA) b. GLYCOLIPIDS – have carbohydrate sugar chain FUNCTIONS: attached to them which helps in recognizing 1. Control center of the cell other cells in the body 2. Contain genetic material (DNA) c. CHOLESTEROL – helps stiffen the membrane 3. Produce ribosomes (nucleolus) B. PROTEINS 4. Essential in cell division a. STRUCTURAL PROTEIN – support and shape ● MITOCHONDRIA – double layered; rod shaped; b. RECEPTOR PROTEIN – help cells communicate membrane enclosed organelle; inner folds are with their external environment through the use called CRISTAE for greater surface area; has its of hormones, neurotransmitter and other own DNA called mtDNA signaling molecules FUNCTIONS c. TRANSPORT PROTEINS – (globular proteins) 1. produces ATP (cell’s energy) transport molecules across cell membranes 2. helps maintain proper concentration of calcium through facilitated diffusion ions d. GLYCOPROTEINS- for cell to cell communication 3. also helps in building certain parts of blood and and transport of molecules across the cell hormones like testosterone and estrogen membrane 4. liver mitochondria have enzymes that detoxify FUNCTIONS: ammonia 1. Main cell shape 5. also plays a role in apoptosis (programmed cell 2. Support and protection death) 3. Controls movement of materials in and out ● ENDOPLASMIC RETICULUM – series of sheets which 4. Barrier between cell and its environment extension of the nuclear membrane; two types: 5. Maintains homeostasis smooth ER (without ribosomes) and rough ER ● CYTOPLASM - the jelly like substance surrounding the (with attached ribosomes) ; Sarcoplasmic ER nucleus within the cell membrane, where the (present in smooth and striated muscle) organelles are embedded. PROTOPLASM - a viscous, viscid substance with jelly-like FUNCTIONS: consistency where many biological and chemical 1. form a transport network throughout the cell cellular processes take place. 2. provide large surface area for chemical reactions 3. play a role in protein synthesis (rough ER) 4. collect and store manufactured material 5. form a structural skeleton to help maintain the shape of the cell 6. produce lipids and steroids (smooth ER) ● GOLGI APPARATUS – membrane bound flattened sacs stacks of flattened pancakes FUNCTIONS: 1. packaging counters of the cell 2. production of glycoproteins 3. secretion of carbohydrates involved in the production of new cell walls 4. production of secretory enzymes 5. transport and storage of lipids 6. formation of lysosomes ● LYSOSOMES – spherical organelles; contain a powerful enzyme called Lysozyme which when released can destroy the cell FUNCTIONS: 1. destruction of unwanted or worn-out cells 2. digestion of material engulfed by the cell 3. release of enzymes outside the cell (exocytosis) 4. complete digestion of a cell after its death (autolysis) ● RIBOSOMES – small cytoplasmic dots found scattered in the cytoplasm or attached to the RER FUNCTION : produce proteins ● PERIXOSOMES (microbodies) – small spherical , membrane bound ; contain enzymes, a catalase which breaks down the highly toxic cellular by-product hydrogen peroxide into water and oxygen preventing the cell to be poisoned; ● VACUOLES - fluid filled sacs; storage tanks of the cell; covering is called tonoplast ; may contain water, wastes, food, maintains turgor pressure in plants ● VESICLES – small sacs ; function for storage, transport, or digest materials within the cell ● CENTRIOLES – hollow cylinders which form the spindle fiber at cell division; helpers in cell division ● CILIA AND FLAGELLA – cilia are hair-like projections, smaller than flagella. FUNCTION : movement ● CYTOSKELETON – found throughout the cytoplasm; web of long tubes and fibers made of protein FUNCTIONS: 1. supports the cell and maintains cell shape 2. also helps certain cells move ● MICROTUBULES – slender, unbranched tubes FUNCTIONS: 1. provides cytoskeleton 2. providing routes in cells along which materials move 3. aids in cell division by forming spindle 4. major component of cilia and flagella 5. form a framework on which cellulose cell wall of plant cells is laid down ● MICROVILLI – tiny finger-like projections of the cell membrane of certain cells like those in kidney tubule, epithelial of the intestines FUNCTION : collectively they form the brush border and help to increase their surface area, aiding absorption