Structure
The cell membrane is made up of two layers that are composed of phospholipids. The bilayer is
formed by the arrangement of phospholipids in a manner that their head regions (which are
hydrophilic) face external environment as well as the internal cytosolic environment. The
(hydrophobic) tails of these phospholipids face each other. Forces underlying the formation of
this bilayer are electrostatic, van der Waals, non-covalent interactions, and hydrogen bonds. This
peculiar arrangement of hydrophilic and hydrophobic layers doesn't allow nucleic acids, amino
acids, proteins, carbohydrates, and ions to pass through the bilayer. Following are the various
parts of the cell membrane.
Integral Membrane Proteins:
These are structures present on the inside, outside, and also throughout the cell membrane.
Fluorescence and electron microscopy can be used in viewing these proteins. These proteins are
present on the entire/whole surface of the cell membrane. Examples of these structures include
the cadherins, integrins, clathrin-coated pits, desmosomes, caveoles, etc.
Peripheral Membrane Proteins:
These proteins are attached/bound to the surface of the membrane by means of hydrogen bonds
and electrostatic interactions. The hydrogen bonds of these peripheral proteins are formed of
hydrophilic phospholipid heads which form the bilayer.
Skeleton of Cell Membrane:
Surface of the cell membrane on the side of cytoplasm is lined by the cytoskeleton. The
framework or cytoskeleton proves to be useful in the processes of organelles like cilia.
Cytoskeleton also helps in anchoring the membrane proteins to the cell membrane.
Composition of Cell Membrane:
Proteins and lipids are important components which form the cell membrane. Different
mechanisms carry out the function of incorporation and removal of materials into and out of the
membrane. The process of the fusion of cell membrane with intracellular vesicles results into
excretion of contents present in vesicles.
Function
Demarcating the boundaries of a cell is the primary function of plasma membrane. The contents
of a cell are supported by this membrane. Not just supporting the matter present in cells, but also
the function of maintaining contact with other cells is carried out by the cell membrane. The
plant cell membranes enjoy extra protection in the form of cell walls; however, in animals, cell
membrane is the only covering/encapsulation. Proteins which compose (or get embedded in) the
membrane carry out the diffusion of elements in a selective manner.
Cross Section of a Eukaryotic and Prokaryotic Cell