CURRICULUM VITAE

Pinaki Sengupta
ps_pharm@yahoo.co.in Cell: +91-9474989394
psg725@gmail.com

Objective: To seek a challenging career in research and development where I can

utilize my education and skill to its full potential while effectively serving and
contributing to the success of the organization.

Synopsis
• Submitted thesis and awaiting for Ph.D. degree in Pharmacy from Department
of Pharmaceutical Technology, Jadavpur University, Kolkata, India.
• Industrial experience of 1.5 years as Junior Scientist in ‘Drug Metabolism and
Pharmacokinetics’ department of Discovery Research division, Dr. Reddy’s
Laboratories Ltd., India.
• Experience in bioanalytical method development and validations with HPLC
and LC-MS/MS.
• Experience in ‘in vivo’ and ‘in vitro’ pharmacokinetic studies in preclinical
species.
• Well-versed with regulatory, pre-clinical and clinical development activities in
industry.
• Extensive computer training, including knowledge of softwares such as Analyst,
Millennium, Chromeleon, Class VP, EZChrom Elite, Spinchrom, WinNonlin etc.

Publication in Journals
Total 16 research papers published in different reputed journals with good impact
factor. Most of the publications are on development and validation of methods in LC-
MS/MS and HPLC, few are on pharmacokinetic study of drugs in animals and human
volunteer.

Paper Presentations
Two oral presentations on development and validation of LC-MS/MS methods in
International Congress of Chemistry and Environment (ICCE) Conference at
Ubonrathchathani, Thailand in Jan 2010 and 1st International Society
BioTechnology (ISBT) Conference at Gangtok, Sikkim, India in Dec 2008.
Educational Qualifications

2007-2010

Ph.D in Pharmacy with National Doctoral Fellowship (NDF), AICTE, under the
guidance of Prof. (Dr.) T. K. Pal, in the Dept. of Pharm. Tech., Jadavpur
University, Kolkata, India.

2004 - 2006

Master in Pharmacy (M. Pharm), Pharmaceutical Chemistry, in the Dept. of

Pharm. Tech., Jadavpur University, Kolkata, India. First Class with cGPA 8.41
out of 10.

2000 – 2004

Bachelor in Pharmacy (B. Pharm) in the Dept. of Pharm. Tech., Jadavpur

University, Kolkata, India. First class with Honours; 77.90 %.

Research Experiences

• 2006 - 2007

I worked in the R&D division of Dr. Reddy’s Laboratory, Hyderabad, India from
July 2006 to October 2007 in the department of Drug Metabolism and
Pharmacokinetics as a Junior Scientist My work involved in vivo
pharmacokinetic study of NCEs in animal species (mice, rat, hamster,
guineapig, rabbit and dog), plasma protein-binding studies, drug-drug
interaction studies, tissue distribution studies, toxicokinetic studies,
development of HPLC/ LC-MS-MS methods of analysis of NCEs and generic
drugs in biological fluids, validation of method of analysis in different matrices,
analysis of samples of clinical trials for NCEs using HPLC/ LC-MS-MS, in vitro
metabolism studies etc. I was involved in the preclinical and clinical
Pharmacokinetics (PK) profiling of molecules synthesized by the Discovery
Research Chemistry Division, Hyderabad and Reddy’s United States
Incorporation (RUSI, Atlanta). Molecules were characterized for their stability,
absorption, distribution, metabolism and excretion in various in vitro and in vivo
models using sensitive tools.
 • 2007 - 2010

I have completed my research work on “Biopharmaceutical evaluation of a

fixed dose combination of pioglitazone and olmesartan medoxomil”. The work
includes

 Pharmacokinetic study of pioglitazone and olmesartan medoxomil

separately and in combination analyzing the plasma samples by LC-
MS/MS.
 Toxicity study of pioglitazone and olmesartan medoxomil separately
and in combination in rats.
 Evaluation of antidiabetic potential of pioglitazone in combination with
olmesartan medoxomil.
 Development and optimization of a fixed dose combination tablet
dosage form containing pioglitazone and olmesartan medoxomil.
 Stability study of the tablet analyzing the sample of the study by HPLC.
 Bioequivalence study of the formulation in healthy human volunteer
analyzing the plasma samples by LC-MS/MS.

Technical Skills

• Acquainted with the operation of HPLC (Shimadzu, Agilient, Waters, Dionex,

Knauer), LC-MS/MS (API-2000, API-3000, API-4000, and API-4000-QTrap),
Ultracentrifuge, Rotary Evaporator, UV-Visible Spectrophotometer, Tablet
Punching Machine, Dissolution Apparatus etc.
• Bioanalytical method development and validation for new chemical entities
(NCEs) and generic drugs using HPLC and LC-MS/MS.
• In vitro screening of NCEs for microsomal stability, CYP liability and protein
binding.
• In vivo experimentations for necessary profiling of molecules such as dosing,
sampling, pharmacokinetic, toxicokinetic and tissue distribution studies.
Scholastic Achievements

• Awarded with ‘Best Oral Presentation Award of ICCE, Thailand’ in

International Congress of Chemistry and Environment Conference (ICCE) at
Ubonrathchathani, Thailand in Jan 2010.
• Awarded with ‘Jadavpur University Travel Grant’ for attending the
International Congress of Chemistry and Environment Conference (ICCE) at
Ubonrathchathani, Thailand in Jan 2010.
• Awarded with ‘Professor Anupam Sengupta Memorial Medal’ by Jadavpur
University for academic excellence in Pharmaceutical Chemistry in M. Pharm.
Qualified Graduate Aptitude Test in Engineering (GATE) conducted by Indian
Institute of Technology (IIT) Delhi, 2004 with a percentile score of 97.88.
• National Doctoral Fellowship (NDF) for pursuing Ph.D. awarded by All India
Council for Technical Education (AICTE), India.
• UGC Research Fellowship in Science for Meritorious Students for pursuing
Ph.D. awarded by University Grant Commission (UGC), India
• UGC Scholarship for pursuing M. Pharm., awarded by University Grant
Commission (UGC), India.

Personal Details

Date of Birth : 18th May, 1980

Nationality : Indian
Passport Details : E7453525/08.08.2014
Address : C/O Prof. (Dr.) Tapan Kumar Pal
Bioequivalence Study Centre,
Dept. Of Pharmaceutical Technology,
Jadavpur University,
Kolkata – 700 032, India.

Declaration

I do hereby declare that the above written particulars are true to the best of my
knowledge and belief.
PINAKI SENGUPTA