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Pathophysiology of Myoma

Precipitating
Factors:
Predisposing - Over Weight
Factors: - Hyperestrogenic
- Advancing Age Etiology: State
- Genetics - Hypertension
Unknown
- Race - Nulliparity
- Stress - Multiparity
- Menopause
- Contraceptives
Pregnancy Early
Menstruation

Increased production of Increased lifetime exposure


estrogen to estrogen

Signs and
Symptoms Stimulates growth of fibroid
- Abdominal
fullness, gas
- Bleeding between Fibroid grows in the walls of the
periods
uterus (anterior)
- Frequent Urination
- Heavy menstrual
bleeding Pelvic Pain
(menorrhagia),
sometimes with the
passage of blood Deform uterine cavity
clots
- Pelvic cramping or
pain with periods
Menorrhagia
- Sensation of fullness
or pressure in lower
abdomen
MYOMA

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