CENTRO ESCOLAR UNIVERSITY

COLLEGE OF NURSING
Manila*Makati*Malolos

Syllabus

PHARMA1 PHARMACOLOGY II Unit: 3 LEC

Subject Title Subject DescriptiveTitle Hours: 54 LEC

PLACEMENT : 3rd Year, 2nd Semester

COURSE DESCRIPTION : The course deals with the study of pharmacology as an integral part of nursing care. This will include pharmacodynamics,
pharmacokinetics, clinical/therapeutic uses and toxicology of drugs.

PRE-REQUISITE : NCM 102, PHARMACOLOGY I

TERMINAL COMPETENCY: Given a client in the clinical setting, the student will be able to apply the concepts and principles of pharmacology to ensure safe
and quality care to patients through correct administration of drugs, effective assessment of drug effects and provision of
relevant health teaching about drugs and drug regimen .

INTERMEDIATE CONTENT SUGGESTED TEACHING TIME EVALU

COMPETENCIES STRATEGY/ ALLOTMENT MEAS
METHODOLOGY REQUIR
At the end of the unit, the PRELIM
students will be able to: UNIT I. PSYCHOPHARMACOLOGY Lecture-Discussion 1 hour Paper and P
1.Discuss the definition of Foundations of Psychopharmacology
psychopharmacology and its 1. Definition Case Study Recitation
significance to nursing practice. 1.1 antipsychotics,
2.Discuss briefly basic concepts 1.2 antidepressants, Workshops Individual/
of psychiatric drugs 1.3 mood stabilizers, Work

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 1.4 anxiolytics, and Actual Visits to Clinical Areas
1.5 stimulants Requireme
Interviewing nurses in the workplace
1.Case Stu
following:
- Effective
Administer
Psychiatric
Medication
-Common
Medication
Among Nu
UNIT II ANTIPSYCHOTIC DRUGS - other rela
1. CONVENTIONAL ANTIPSYCHOTICS 6 hour
2. ATYPICAL ANTIPSYCHOTICS 2. Drug Stu
3. NEW GENERATION ANTIPSYCHOTIC Major Dru
4. DRUGS USED TO TREAT EXTRAPYRAMIDAL SIDE
EFFECTS 3.Journal (
UNIT III ANTIDEPRESSANTS 3 hours the various
1. Tricyclic and the related cyclic antidepressants
2. Selective serotonin reuptake inhibitors (SSRIs)
3. Monoamine oxidase inhibitors (MAOIs)
4. Other antidepressants:
4.1 Venlafaxine (Effexor),
4.2 Bupropion (Wellbutrin),
4.3 Trazodone (Desyrel), and
4.4 Nefazodone (Serzone)

UNIT IV Mood Stabilizers 3 hours

1. Lithium is the most established mood stabilizer;
2. Carbamazepine (Tegretol)

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 3. Valproic acid (Depakote, Depakene),
4. Others:
4.1.1Gabapentin (Neurontin)
4.1.2Lamotrigine (Lamictal)
4.1.3Clonazepam (Klonopin).
UNIT V ANXIOLYTICS
1.BENZODIAZEPINES
2. NONBENZODIAZEPINES
UNIT VI Stimulants 3 hours
1. Methylphenidate (Ritalin),
2. Pemoline (Cylert), and
3. Dextroamphetamine
UNIT VII. SPECIAL DRUGS
1. Disulfiram (Antabuse)
2. Cognitive enhancers
a. Stimulant Cognitive enhancers
i. Donezepil (Aricept)
ii. Galantamine ( Reminyl)
iii. Rivastigmine (Exelon)
b. Non-stimulant cognitive enhancers
i. Atomoxetine(Strattera)

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 INTERMEDIATE CONTENT SUGGESTED TEACHING TIME EVALUATIVE
COMPETENCIES STRATEGY/ ALLOTMENT MEASURES/
METHODOLOGY REQUIREMENTS
At the end of the unit, the MIDTERMS 2 hour Paper and Pencil Tests
students will be able to: Drugs for Disturbances in Neurologic Function, Eye
At the end of this unit the student and Vision Disorders, Hearing Disorders and Recitation
will be able to: Muskuloskeletal Disorders
A. Provide safe and quality care Individual/Group Work
1. Explain the mechanism s of UNIT V. Drugs for Neurologic Disorders
action of drugs used for 1. Drugs for Seizure Disorders Requirement:
neurological disorders 12.1. Definition/Classification of Seizures
2. Identify the mechanism of 1.2. benzodiazipines 1.Case Study on the
actions, uses, and side effects of 1.3. hydantoins following:
drugs used for neurologic 1.4. succinimides - Effective Practices in
disorder 1.5. Miscellaneous Anticonvulsants Administering
3. Describe the three general 1.5.1. carbamazepine Medications
adverse effects associated with 1.5.2. gabapentin Clayton’s Basic Pharmacology for -Common Reasons of
drugs for neurologic disorders 1.5.3. lamotrigine Nurses 14th edition pp. 296-315 Medication Errors
4. Describe the nursing process 1.5.4. levetiracepam Among Nurses
including client teaching related 1.5.5. oxcarbazepine
to drugs for neurologic disorders 1.5.6. primidone
1.5.7. tiagabine
1.5.8. topiramate
1.5.9. valproic acid
1.5.10. zonisamide
1.6. Drug of choice for each type of seizure

2. Parkinson’s Disease
2.1. Dopamine Agonists
2.1.1. amantadine
2.1.2. apomorphine

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 2.1.3. bromocriptine mesylate
2.1.4. carbidopa
2.1.5. levidopa
2.1.6. pergolode mesylate
2.1.7. pramipexole
2.1.8. ropinirole
2.2. COMT Inhbitor
2.2.1. entacapone
2.3. Anticholinergic Agents Clayton’s Basic Pharmacology for
2.4. Miscellaneous Antiparkinsonian Agents Nurses 14th edition pp. 231-248
2.4.1. selegiline

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At the end of the unit, the Unit VI. . Drug Therapy for Eye, Ear, Nose and 2hour Paper and Pencil Tests
students will be able to: Throat Disorders Clayton’s Basic Pharmacology for
At the end of this unit the student Drugs Affecting Autonomic System Nurses 14th edition pp. 207-215 Recitation
will be able to: 1.1.Adrenergic Agents
A. Provide safe and quality care 1.1.1. norepinephrine Individual/Group Work
1. Explain the mechanism s of 1.1.2. dopamine
action of drugs used for eye, ear, 1.1.3. epinephrine Requirement:
nose and throat disorders. 1.2.Alpha & Beta-Adrenergic Blocking Agents
2. Identify the mechanism of 1.2.1. cebutolol 1.Case Study on the
actions, uses, and side effects of 1.2.2. esmolol following:
drugs used for eye, ear, nose and 1.2.3. propranolol - Effective Practices in
throat disorders. 1.2.4. metprolol Administering
3. Describe the three general 1.3. Cholinergic Agents Medications
adverse effects associated with 1.3.1. bethanechol -Common Reasons of
drugs for eye, ear, nose and throat 1.3.2. edrophonium Medication Errors
disorders. 1.3.3. neostigmine Among Nurses
4. Describe the nursing process 1.3.4. physostigmine
including client teaching related 1.3.5. pilocarpine
to drugs for eye, ear, nose and 1.3.6. pyridostigmine
throat disorders. 1.3.7. ambenonium
1.3.8. guanidine
1.4. Anticholinergic Agents
1.4.1. atropine
1.4.2. belladonna
1.4.3. dicyclomine
1.4.4. glycopyrrolate
1.4.5. mepenzolate
1.4.6. propantheline

2. Ear disorders
2.1. Antimicrobials-review

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 3.Nose Disorders-review
3.1. Decongestants
3.2. Antihistamines

4. Throat Disorders

At the end of this unit the student Unit VII. Drugs for Musculoskeletal Disorders Clayton’s Basic Pharmacology for 3 hours Paper and Pencil Tests
will be able to: 1.Centrally Acting Skeletal Muscle Relaxants Nurses pp. 735-744
A. Provide safe and quality care 1.1. casiprodol Recitation
1. Explain the mechanism s of 1.2. chlorzoxazone
action of drugs used for 1.3. cyclobenzaprine Individual/Group Work
musculoskeletal disorders. 1.4. metaxalone
2. Identify the mechanism of 1.5. methocarbamol Requirement:
actions, uses, and side effects of 1.6. orphenadrine citrate
drugs used for musculoskeletal 1.7. tizanidine 1.Case Study on the
disorders. 1.8. baclofen following:
3. Describe the three general 2.Direct-Acting Skeletal Muscle Relaxant - Effective Practices in
adverse effects associated with 2.1. dantrolene Administering
drugs for musculoskeletal 3.Neuromuscular Blocking Agents Medications
disorders. -Common Reasons of
4. Describe the nursing process Medication Errors
including client teaching related Among Nurses
to drugs for musculoskeletal
disorders.

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 INTERMEDIATE COMPETENCIES CONTENT
At the end of the unit, the students will be able to: FINALS
1.Discuss the different drugs appropriate for the treatment of UNIT I. Drugs for Communicable Diseases
different disorders. 5. Pulmonary Tuberculosis
2.Discuss briefly basic concepts of drugs like sources, drug 5.1 Definition
names, standards, information and evaluation. 5.2 Primary Drugs
5.2.1 Streptomycin
5.2.2 Isoniazid
5.2.3 Rifampicin
5.2.4 Pyrazinamide
5.2.5 Ethambutol
5.3 Secondary Drugs
5.3.1 Capreomycin

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 5.3.2 Ethionamide
5.3.3 Para-aminosalicylate sodium
5.3.4 Cycloserine
1.4 Phases of Treatment
1.4.1 Initial Phase
1.4.2 Continuation phase
2. Pneumonia
2.1 Definition
2.2 Drugs
2.2.1 Streptococcal pneumonia
a. Penicillin
b. Cefotaxime
c. Fluoroquinolone
2.2.2 Haemophilus pneumonia
a. Amoxicillin-Clavulanate
b. Non-beta-lactamase- Amoxicillin
2.2.3 Mycoplsma pneumonia
a. Macrolide
b. Tetracycline
2.2.4 Viral Pneumonia
a. Oseltamivir
b. Zanamivir
2.2.4 Chlamydia pneumonia
a. Fluoroquinolone
2.2.5Hospital-acquired Pneumonia/Pseudomonas Pneumonia
a. Penicillin + Ciprofloxacin
b. Levofloxacin
c. Aminoglycoside
2.2.6 Klebsiella pneumonia
a. Meropenem
b. Levofloxacin

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 c. Piperacillin/Tazobactam + Amikacin
3. Malaria
3.1 Definition
3.2 Drugs
3.2.1 Chloroquine
3.2.2 Primaquine
4. Leptospirosis
4.1 Definition
4.2 Drugs
4.2.1 Mild Leptospirosis
a. Doxycycline
b. Amoxicillin
4.2.2 Moderate to Severe Leptospirosis
a. Penicillin G
b. Ampicillin
c. Ceftriaxone
5. Filariasis
5.1 Definition
5.2 Drugs
5.2.1 Diethylcarbamazine
5.2.2 Albendazole
5.2.3 Doxycycline
6. Typhoid fever
6.1 Definition
6.2 Drugs
6.2.1 Ciprofloxacin
6.2.2 Chloramphenicol
6.2.3 Azithromycin
7. Viral Hepatitis
7.1 Definition
7.2 Drugs

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 7.2.1 Lamivudine
7.2.2 Interferon
8. Rabies
8.1 Definition
8.2 Drugs
8.2.1 Rabies Immunoglobulin (RIG)- post-exposure prophylaxis
9. Tetanus
9.1 Definition
9.2 Drugs
9.2.1 Penicillin
9.2.2 Metronidazole
10. Gonorrhea
10.1 Definition
10.2 Drugs
10.2.1 First Line
a. Ceftriaxone
b. Doxycycline
10.2.2 Alternative
a. Ceftizoxime
b. Cefotetan + Probenecid
11. Chlamydia
11.1 Definition
11.2 Drugs
11.2.1 Doxycycline
11.2.2 Tetracycline
11.2.3 Azithromycin (Pregnant)
12. HIV/AIDS
12.1 Definition
12.2 Drugs
12.2.1 Reverse-Transcriptase inhibitors
a. Zidovudine

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 b. Didanosine
c. Zalcitabine
12.2.2 Protease inhibitors
a. Saquinavir
b. Ritonavir
12.2.3 Integrase Inhibitor
a. Raltegravir
13. Carbuncle
13.1 Definition
13.2 Drugs
13.2.1 Penicillin G
13.2.2 Vancomycin
14. Scabies
14.1 Definition
14.2 Drugs
14.2.1 Permethrin cream
14.2.2 Lindane
15. Schistosomiasis
15.1 Definition
15.2 Drugs
15.2.1 Praziquantel
16. Ascariasis
16.1 Definition
16.2 Drugs
16.2.1 Albendazole
16.2.2 Ivermectin
17. Enterobiasis
17.1 Definition
17.2 Drugs
17.2.1 Mebendazole
17.2.2 Pyrantel pamoate

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At the end of this unit the student will be able to: UNIT II. ONCOLOGIC PHARMACOLOGY
1.Identify the basic principles of cancer treatment 1.Cytotoxic antineoplastic drugs are usually classified in terms
2.Discuss the cell cycle of their mechanisms of action
3. Identify the two drug classifications. 1.1 alkylating agents ( Nitrogen mustard derivatives, nitrosoureas, platinum compounds)
4. Identify appropriate drugs for different cancers and their side- 1.2 and anti-metabolites
effects. 1.2.1 folic acid antagonist (eg, methotrexate),
5. Discuss the nursing management of patients undergoing 1.2.2 purine antagonists (eg, mercaptopurine), and
chemotherapy. 1.2.3 pyrimidineantagonists (eg, fluorouracil)
2. Cytotoxic antineoplastic drugs are usually classified in terms their sources
2.1 Plant alkaloids
2.1.1 camptothecin (eg, topotecan),
2.1.2 podophyllotoxin (eg, etoposide),
2..1.3 taxanes (eg, paclitaxel), and
2.1.4 plants of the Vinca genus (eg, vincristine)
2.2 Anti-tumor antibiotics.
2.2.1 Doxorubucin
2.2.2 Bleomycin
3. Other drugs used in chemotherapy are immunostimulants, hormones, hormone inhibitors, and
cytoprotectants.
At the end of this unit the student will be able to: UNIT III. Drugs Used in Acute Biologic Crisis/Emergency Drugs
1. define biologic crisis and emergency. 1. Definition
2. Identify different emergency drugs for common 2. Drugs Used in:
emergencies. 2.1 Cardiac Arrythmias
2.2 Cerebrovascular Accident
2.3 Acute Exacerbation of Bronchial Asthma
2.4 Seizures
2.5 Pain
2.6 Hypertensive Crisis

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REFERENCES:

Allen, L, et al., Ansel’s Pharmaceutical Dosage Forms and Drug Delivery Systems, 8th edition, Lippincott, 2005
Clayton, B., et al., Basic Pharmacology for Nurses, 14th edition, Elsevier, Singapore, 2007
Guitierrez, Kathleen, et al, Pharmacology for Nursing Practice, 1st ed., Mosby, 2003
Karch, Amy M., Focus on Nursing Pharmacology, 2nd edition, Lippincott, 2003.
Kee, Joyce LeFever et al., Pharmacology A Nursing Process Approach, 2nd edition, W.B. Saunders Company, 2003
Lilley, L., et al., Pharmacology and the Nursing Process, 5th edition, Elsevier, Singapore, 2007
Leda Mckenry & Evelyn Salerno. Pharmacology in Nursing. St. Louis: The CV Mosby Company, 1989
.
Drug Handbook
Springhouse, Nurses Drug Guide 2008, Lippincott, 2008
Lippincott’s Nursing Drug Guide, Lippincott, 2009

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