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2010

Faculty of Science
Biomedical Science Handbook
Contents

Biomedical Science at
The University of Auckland 3

Important dates 4

General Education 6

Changes to Regulations 8

Entry requirements 9

Admission and enrolment procedures 11

Biomedical Science 14

Courses 16
Year 1 courses 17
Year 2 courses 20
Year 3 suggested options 24
Course list 32
Postgraduate study in Biomedical Science 37
Programme contacts 38
Postgraduate courses 39

Advice and support for students 47


Academic honesty 48
The University of Auckland Library 51
Student Services 52
Improve your English langauge skills 56
Students support services 57
Campus maps 58

Disclaimer
Although every reasonable effort is made to ensure
accuracy, the information in this document is provided
as a general guide only for students and is subject to
alteration. All students enrolling at The University of
Auckland must consult its official document, the current
Calendar of The University of Auckland, to ensure that
they are aware of and comply with all regulations,
requirements and policies.

2 | 2010 Biomedical Science Handbook


Biomedical Science
Biomedical Science encompasses those
disciplines relevant to an understanding of the
scientific basis of health and disease in humans
and animals. This research-led field has
experienced rapid growth over the past decade
and is associated with a high level of public
awareness and approval.

The University of Auckland is acknowledged as a


centre of excellence in this field reflecting the high
quality of the biomedical research carried out in
the Faculty of Medical and Health Sciences and
the School of Biological Sciences.

Biomedical Science Programmes


The Biomedical Science programme is designed
for very able students with an interest in
emerging areas of biomedical science including
genomics, microbiology, biochemistry, nutrition
and cardio and neural science, and its application
to improve human and animal health.

The Biomedical Science programmes are


co-taught by the Faculties of Science and Medical
and Health Sciences, with lectures split between
the City and Grafton campuses.

The Honours programme is designed to equip a


selected group of academically able students to
progress efficiently into PhD training and is
intended for people who aim to fill leadership
roles in research and development.

2010 Biomedical Science Handbook | 3


Students who are not selected for Honours may Biomedical Science and must maintain at least a
continue through the Postgraduate Diploma in B average. At the end of their third year, selected
Science (PGDipSci) (Biomedical Science) and students should apply on nDeva for admission to
Master of Science (MSc) to PhD as grades permit. the BSc(Hons)-Biomedical Science programme.

Graduates of the Biomedical Science programme Students who are not selected for Honours may
will have an internationally accepted also complete the third year and graduate
qualification, excellent research skills and the BSc-Biomedical Science. These students may
knowledge to work within some of the world’s continue through the Post Graduate Diploma in
most rapidly advancing scientific fields. Science (PGDipSci) (Biomedical Science) and
Master of Science (MSc) to PhD as grades permit.
During the first three years, students enrol in
courses towards a BSc-Biomedical Science which Alternatively they may complete a BSc in
will deliver rigorous scientific training in a range Biological Science, Pharmacology or Physiology. A
of disciplines and provide a strong foundation for pathway to Doctorate is available to these
a number of professional careers. They will also students through the Master of Science, subject
give a unique insight into the principles to meeting the academic requirements for entry.
underlying an important area of modern
biological research. Careers in Biomedical Science
Foundation teaching for Biomedical Science will For Biomedical Science graduates and
be covered in the first two years of the particularly those with the appropriate
programme. subsequent postgraduate training, there are a
variety of opportunities in universities, research
Up to 60 students will be selected on academic institutes and pharmaceutical/biotechnology
merit for the BSc (Hons)-Biomedical Science industries. Private sector employment in the latter
degree at the end of the second year but will fields is particularly strong in the United States
complete the third year towards the BSc- and Europe. Significant growth in this area is
anticipated in New Zealand.

Important dates
Closing dates for applications for admission in 2010
1 December 2009 Deadline for new students to submit Application for Admission if 2010
programme includes Summer School courses.
8 December 2009 Deadline for new students to submit Application for Admission if 2010
programme includes Semester One and Semester Two courses only.

If you are a new student, only one Application for Admission is


required. This form is due on either 1 December or 8 December
depending on whether you want to take Summer School as well.

Applications received after these dates may be accepted if there are


places available.

4 | 2010 Biomedical Science Handbook


Academic year 2010
Summer School – 2010
Lectures begin Tuesday 5 January
Auckland Anniversary Day Monday 1 February
Deadline to withdraw from summer school courses 1 week before the end of lectures
Waitangi Day Saturday 6 February
Lectures end Friday 12 February
Study break/exams* Monday 15 February - Wednesday 17 February
Summer School ends Wednesday 17 February
Semester One – 2010
Semester One begins Monday 1 March
Mid-semester break/Easter Friday 2 April - Saturday 17 April
ANZAC Day Sunday 25 April
Graduation Thursday 29 April - Friday 7 May
Deadline to withdraw from first semester courses 3 weeks before the end of lectures
Queen’s Birthday Monday 7 June
Lectures end Saturday 6 June
Study break/exams* Saturday 6 June - Monday 29 June
Semester One ends Monday 28 June
Inter-semester break Tuesday 29 June - Saturday 17 July
Semester Two – 2010
Semester Two begins Monday 19 July
Mid-semester break Monday 30 August - Saturday 11 September
Graduation Tuesday 21 September - Thursday 23 September
Deadline to withdraw from second semester 3 weeks before the end of lectures
courses
Lectures end Saturday 23 October
Study break/exams* Saturday 23 October - Monday 15 November
Labour Day Monday 25 October
Semester Two ends Monday 15 November
Hand in BSc(Hons)(BIOMED) Dissertation by 3pm Friday 12 November
Semester One – 2011
Semester One begins Monday 28 February 2011
* Aegrotat and Compassionate Applications must be submitted within 1 week of the date that the
examination affected took place.
Deadline for withdrawal from double semester courses is three weeks before the end of lectures in the
second semester.

2010 Biomedical Science Handbook | 5


General Education

What is General Education? What must I take?


Courses in General Education are a distinctive BSc students must take two General Education
feature of University of Auckland bachelors courses (30 points) in their degree. Students
degrees.  The General Education programme has taking a BSc specialisation in Biomedical Science
been designed to produce graduates with wishing to apply to the MBChB after their first
flexibility, critical thinking skills, and an year must take one General Education course in
appreciation and understanding of fields outside Year 1. Students not applying for medicine may
of their usual area of study. delay their General Education to another year.

Who must take General Education? How do I know what to take?


The requirement for General Education applies to Students will choose General Education courses
students who enrol at The University of Auckland from schedules which list courses available to
to begin their first undergraduate degree. their particular degree or conjoint combination.
The schedules have been developed so that
students will take General Education courses that
allow them to explore areas of interest outside of
their degree subjects. The schedules and courses
available to BSc students taking a specialisation
in Biomedical Science are:

6 | 2010 Biomedical Science Handbook


Schedule available to the Biomedical
Science programme
Schedule A: Music, Art and
Contemporary Issues
ANTHRO 106G LAW 121G
ARCHHTC 102G MUSIC 144G
DANCE 101G MUSIC 149G
DANCE 200G PLANNING 100G
FINEARTS 210G POPHLTH 104G
GEOG 103G THEOLOGY 101G
GEOG 104G
Schedule B: Humanities and Social
Sciences
ANTHRO 104G EUROPEAN 100G
ANTHRO 105G FTVMS 110G
ARTHIST 110G FTVMS 215G
ASIAN 140G HISTORY 103G
CLASSICS 110G LINGUIST 101G
COMPLIT 100G MAORI 130G
DIABLTY 113G POLITICS 107G
EDUC 120G POLITICS 140G What if the course is available as
EDUC 121G SOCIOL 101G non-General Education as well?
EDUC 122G SOCIOL 220G In some cases, courses are available both as part
of the General Education Programme and as part
ENGLISH 241G YOUTHWRK 152G
of the portfolio of regular degree courses. If
Schedule C: Business and Society students are taking a dual purpose course as
ACCTG 151G INTBUS 151G part of the General Education programme, they
COMLAW 151G MKTG 151G will enrol in the G version of the course (e.g.
ECON 151G HISTORY 103G). The classes and programme of
study will be the same for all students.
Schedule G: Communication
BUSINESS 151G PHIL 105G
Where can I get more information?
ENGLISH 121G SCIGEN 101G
The General Education website, www.auckland.
Schedule H: Languages ac.nz/generaleducation enables students to
CHINESE 100G MAORI 101G view the courses available to them and provides
FRENCH 101G RUSSIAN 100G the information needed for course selection.
GERMAN 101G SAMOAN 101G
Students are encouraged to seek advice on
ITALIAN 106G SPANISH 104G General Education in their degree from the
JAPANESE 130G TONGAN 101G Science Student Centre.
KOREAN 110G

Note: BSc(Biomedical Science) students may


not take STATS 101G to meet their General
Education requirement.
2010 Biomedical Science Handbook | 7
Changes to regulations
of Auckland website and should serve as a guide
to students for matching their courses to their
interests.

Note: From 2010, 45 points from BIOSCI 201-203


will be required. Students who commenced their
programme in 2006-2009 may complete 30
points from this group.

Students who are following the options as


specified in the 2006-2009 regulations will meet
the requirements for graduation under 2010
regulations.

The new regulations which will govern completion


are:

• 90 points: BIOSCI 101, 106, 107, CHEM 110,


PHYSICS 160, MEDSCI 142

• 60 points: BIOSCI 201-203, MEDSCI 205

• At least 45 points: MEDSCI 201, 203, 204,


206, (BIOSCI 204 or MEDSCI 202), PSYCH 202

Transition Regulations • At least 15 points: STATS 101, 108, BIOSCI 209


From 1 January 2011, arrangements put in place • At least 30 points: BIOSCI 347-358
for all students who had commenced their
programme prior to 2006 will no longer apply. • At least 30 points: MEDSCI 301-315
Any transitional students who have not completed
their programme by this time must complete • At least 15 points at Stage III from BIOSCI,
under the 2010 regulations. MEDSCI, CHEM 390, 392 or PSYCH 305

New web address for Transition Regulations • At least a further 45 points from the schedule
Handbook: www.auckland.ac.nz/current for the Bachelor of Science
students/Academic information/Academic
• Students must also complete 30 points from
programme changes 2006
courses listed in the General Education
Schedule approved for this degree.
Changes for 2010
From 1 January 2010 the Biomedical Science
regulations will change to allow more flexibility
for students. While students will no longer be
required to meet the full requirements of an
option to graduate, these sets of courses will be
publicised through handbooks and The University

8 | 2010 Biomedical Science Handbook


Entry requirements
Entry Requirements for
Part I of BSc-Biomedical Science
Entry to BSc-Biomedical Science is limited.
Selection into this plan will require the University
Entrance Standard and an NCEA rank score of at
least 230, or a CIE score of at least 240, or
equivalent. Students entering from NCEA will be
considered according to their best 80 credits at
Level 3 or higher over a maximum of five
approved subjects weighted by the level of
achievement attained in each set of credits.
Students entering with alternative qualifications,
such as IB will also be considered on their
achievement.

Some courses within the Biomedical Science


programme have limited entry (e.g. BIOSCI 107
and MEDSCI 142). All students will be considered
for entry to these courses (NCEA students will be
considered according to their best 80 credits at
Level 3 or higher over a maximum of five
approved subjects weighted by the level of
achievement attained in each set of credits).

Students who do not meet the entry requirement Year 13 Preparation For Entry
for the BSc-Biomedical Science but who have
Students should take a range of science subjects
gained University Entrance, and NCEA rank score
at year 13 or NCEA Level 3, including biology,
of at least 150 or a CIE rank score of at least 140
chemistry and physics. Subjects that enhance
will be eligible for entry to other majors within the
literacy are also encouraged, and students are
BSc degree (e.g. Biological Sciences, Chemistry,
strongly encouraged to include a humanities
Physiology, etc). Students with rank scores below
subject as well as mathematics.
these may be considered subject to space.
Students can enroll in alternative first year
courses to obtain higher grades and may apply Entry Into Medicine
for BSc-Biomedical Science in the following year. Biomedical Science students who gain a B+
Students in this category who are intending to average in their first year of study may be eligible
apply for medicine must do the Year 1 courses for to be considered for an interview for entry to the
BSc-Biomedical Science within one academic year undergraduate medical course. Students wishing
and should therefore not begin the required to be considered for an interview need to take
courses until the following year even if admission POPLHLTH 111 as their elective course and an
to BSc-Biomedical Science is approved for second approved General Education course in Year 1.
semester. They will also be required to sit the UMAT
examination in July 2010.

2010 Biomedical Science Handbook | 9


There are no advantages in taking either the plan your timetable prior to enrolment. Certain
BHSc or BSc-Biomedical Science as a pathway streams have been reserved for BSc-Biomedical
into medicine. Students should choose their Science students only - this information is
programme according to their ability, interest displayed in Class Search under Notes.
and preference.
• If you accept BSc-Biomedical Science and then
decide to accept an alternative programme or
Selection Criteria for Honours
major, please contact the Science Student
Up to 60 students will be selected into Honours. Centre (+ 64 9 373 7599 ext. 87020) so that
Selection is based on calculated GPA over the we can discontinue the BSc or change the
Year 2 core courses: MEDSCI 205, 45 points: major for you.
BIOSCI 201-203 and at least 45 points from
MEDSCI 201, 203, 204, 206, (BIOSCI 204 or • Students who do not have a pass in senior
MEDSCI 202), PSYCH 202. school Chemistry are advised to take CHEM
150 in first semester and then take CHEM 110
At the end of their third year, selected students in second semester.
should apply on nDeva for admission to the
BSc(Hons)-Biomedical Science programme. To
remain eligible for Honours, students must
BSc & BSc(Hons)-Biomedical
maintain a B average over their third year.
Science Programme
Core Courses:
Some third year students may be considered if
Year 1 & Year 2
additional places are available.
• 90 points: BIOSCI 101, 106, 107, CHEM 110,
Information sessions for students entering PHYSICS 160, MEDSCI 142
Honours will be held in Semester 2.
• 60 points: BIOSCI 201-203, MEDSCI 205
Useful Tips
• At least 45 points: MEDSCI 201, 203, 204,
• When applying, you have up to four 206, (BIOSCI 204 or MEDSCI 202), PSYCH 202
programme choices per application. If BSc-
Biomedical Science is your first choice, you • 15 points: STATS 101, 108, BIOSCI 209 (may
should also apply for BSc in an alternative be completed at any time)
major (e.g. Biological Sciences, Chemistry ,
Physiology, etc) as your second choice in case Year 3
you don’t meet the requirements for BSc- • At least 30 points: BIOSCI 347 – 358
Biomedical Science. If you have University
Entrance, and an NCEA rank score of at • At least 30 points: MEDSCI 301 – 315
least150 or a CIE rank score of at least 140,
you will be approved automatically into these • At least 15 points at Stage 3 from: BIOSCI,
alternative pathways, and can enroll in MEDSCI, CHEM 390, 392 or PSYCH 305
alternative first year courses to obtain higher
• At least a further 45 points from the schedule
grades that may allow entry to BSc-Biomedical
for the Bachelor of Science
Science in the following semester or year.

• Once you have accepted your place in


BSc-Biomedical Science, you should enrol as
soon as possible as places in some courses are
also limited. Use Class Search on nDeva to

10 | 2010 Biomedical Science Handbook


Admission and enrolment
procedures
New Students
If you are not enrolled at The University of The closing date for most undergraduate Science
Auckland in 2009, apply online at www.auckland. applications is 8 December 2009.
ac.nz/apply_now. If you are unable to access our
website, please call 0800 61 62 63 or visit the If you want to take courses at Summer School, or
Student Information Centre at 22 Princes Street, wish to apply to Sport and Exercise Science or the
Auckland. This is open Monday to Friday from Bachelor of Optometry, applications close 1
8am – 6pm and Saturday 9am – 12noon during December 2009.
peak times.
Only one application is required.
Student Information Centre
Room 112, Level 1 (Ground Floor)
The ClockTower Building, 22 Princes Street
Auckland City Campus

Phone: 64 9 373 7599 ext 88199


Fax: 64 9 367 7104
Email: studentinfo@auckland.ac.nz

2010 Biomedical Science Handbook | 11


Heading B

After submitting your application: Returning Students


Your application will be acknowledged by post, If you are currently enrolled at The University of
and you will receive your Net ID, password and a Auckland in 2009, and would like to change your
list of items required to evaluate your eligibility to existing programme (for example MSc after
be admitted to the University and to your chosen completion of BSc(Hons)), you should apply on
programme/s. If you are submitting a hard copy nDeva (www.auckland.ac.nz/nDeva) by logging
application form, you are required to include on and clicking on Add/Change programme.
relevant documentation at the time of
submission. When all documentation You will be able to enrol via nDeva, but if you
requirements have been met, your application would like help, please call 0800 61 62 63 or visit
will be assessed by the Admissions Office and the Student Information Centre or the Faculty of
relevant faculties. If your application is approved, Science Student Centre (Ground Floor, Building
you will receive an offer of place. 301, 23 Symonds Street). Postgraduate students
may need to contact their department for
Your Net ID and password allow you to access enrolment to be completed.
the University’s nDeva site, enabling you to
monitor the progress of your application and The University of Auckland will be open for
check if further documentation is required. enrolment from November 2009 to the end of
February 2010. You are welcome to visit during
Once you have accepted an offer of place, you normal office hours to seek academic or
will gain access to the Enrolment module on enrolment advice or assistance in completing
nDeva and you can then proceed to enrol in your enrolment.
courses online. Postgraduate students may need
to contact their department for enrolment to be
completed.

12 | 2010 Biomedical Science Handbook


Undergraduate Enrolment - where to from here?

Enquire
Visit www.auckland.ac.nz or contact our student advisers for any information you need.
Phone: 0800 61 62 63 | Email: studentinfo@auckland.ac.nz
Student Information Centre: Room 112, ClockTower, 22 Princes St, Auckland

Apply for a place in a programme(s)


Do you have internet access, or can you come on to campus to our help labs?

Yes No
• Log on to www.auckland.ac.nz Phone: 0800 61 62 63
• Click on Apply Now. (or +64 9 308 2386 if overseas)
Email: studentinfo@auckland.ac.nz
• Complete the online Application for a place in your programme(s) of choice.
• You will receive an acknowledgement letter asking you to provide specific certified The ClockTower Call Centre will
documents (and in some cases to complete other requirements*) before your forward required information to
application can be assessed. The letter will also tell you how to access the University’s you.
nDeva system to complete the next steps.

Offer
Your application will be assessed and, if successful, an “Offer of a place in a programme” letter will be mailed to you. This
normally happens from mid January.**

Accept
Accept or decline your offer of a place in a programme online. Remember – you still need to enrol in your courses!

Enrol in your choice of courses * For some programmes, you may be


required to submit supplementary
For help with choosing courses you can: information (eg, a portfolio of work, referee
reports, an online form) or to attend an
• talk to staff for advice, and listen to talks on various programmes at Courses and
interview/audition. If you have not already
Careers day in late August 2009 and Course Advice Day in late January/ done this, any outstanding requirements will
February 2010 be explained in the acknowledgement letter
– ensure that you follow them up as quickly
• refer to www.science.auckland.ac.nz or to publications relating to your
as possible.
programme, or to The University of Auckland Calendar. For programme
publications call 0800 61 62 63. The Calendar is for sale in bookshops or can be ** You can also check the status of your
accessed from www.auckland.ac.nz Click on “Current Students” then “University application online using your login and
password (if you don’t know these, check the
Calendar” in the Quick Links box
instructions on your acknowledgement
• go online to check the timetable for your chosen courses letter). If you are not offered a place in the
programme(s) of your choice, you will
• for more information visit the Faculty of Science Student Centre, Ground Floor, receive a letter outlining alternative options.
Building 301, 23 Symonds Street Please follow the advice on the letter or get
• or call 0800 61 62 63. in touch with the ClockTower Call Centre.
Your final offer of a place is dependent both
Enrol in courses via the online nDeva system, using your login and password. on you gaining admission to the University
(which for school leavers may be dependent
Pay your tuition fees.
on your final school results) and assessment
by the faculty offering the programme.

You are now a University of Auckland student. Congratulations!

2010 Biomedical Science Handbook | 13


Biomedical Science
The first year of the programme provides Students should also plan their course with some
foundation teaching. First year students will take consideration of the programme they would
five courses in biological science, chemistry and follow should they not be selected for MBChB.
physics from the overlapping first year, in
common with students enrolled in BHSc and In most cases, students who have completed the
other programmes. All students are strongly first year courses of the BSc-Biomedical Science
encouraged to include biological sciences, may also, with minimal addition of other first year
chemistry, physics or statistics as electives. courses (either as an elective course or in their
Students who wish to apply for medicine must second year), gain access to the following
include POPLHLTH 111 as an elective. programmes in science.

All Biomedical Science students must complete a • BOptom – Optometry


statistics course and 30 points from General leads to registration as an optometrist, as well
Education courses before the end of their as offering opportunities to study vision
programme. science. (Students must apply to be selected for
this programme).
Compulsory for Year 1 • BSc – Bioinformatics
• 90 points: BIOSCI 101, 106, 107, CHEM 110, offers computation and biology. Applications of
PHYSICS 160, MEDSCI 142. computer modelling and analysis to biology.
Fast growing field, especially in relation to
• 15 points from an approved General Education gene technology and analysis
course.
• BSc – Biological Science
• Plus 15 points in an elective course genetics / proteomics / ecology / gene
technology / biotechnology / biochemistry /
Transferring to other courses after plant and animal studies / ecology /
Year 1 microbiology. Strong lead to marine studies
and environmental programmes, in
Entry to Medicine combination with other subjects.
The two routes to selection for medicine from the
end of first year are the Bachelor of Health • BSc – Chemistry
Sciences (BHSc) and the Bachelor of Science in skills in organic, inorganic, physical and
Biomedical Science (BSc). For 2010, Biomedical analytical chemistry.
Science students who gain an average of B+ or
better in their first year of study will be eligible for • BSc – Food Science
consideration to be interviewed for selection to structure, properties and composition. Includes
medicine. Students wishing to apply for medicine nutriceuticals, functional foods and genetically
must include POPLHLTH 111 as an elective, and modified foods. Preparing Scientists for the
complete a General Education course in year 1. food industry.
They will also be required to sit the UMAT
• BSc – Medicinal Chemistry
examination in July 2010.
organic chemistry degree looking at drug
design. Includes courses on industrial and
ethical issues and a current emphasis on
derivatives from natural substances.

14 | 2010 Biomedical Science Handbook


• BSc – Pharmacology • BSc – Sport and Exercise Science
involves the study and description of the action More than just sport: strong programmes in
of drugs and chemicals on cells, tissues and exercise and cardiac rehabilitation, as well as
the whole body. sport psychology, leisure studies and mobility.
(Students must apply to be selected for this
• BSc – Physiology programme).
offers broad training in scientific and technical
skills that naturally feed into other disciplines. • BTech – Biotechnology
Physiology is an important subject and along developing the industrial application of the
with neurophysiology and neuroscience (which new biotechnologies, particularly in genetics
study the brain and nervous system) is one of and DNA technology, in conjunction with the
the fastest growing areas in biology. Faculty of Engineering. Good links to
companies active in the field.
• BSc – Psychology
a range of options from neuroscience and • BTech – Medical Physics and Imagining
cognitive psychology to educational and Technology
clinical psychology. provides a strong background in physics and
appropriate areas of Biomedical Science, and
to supplement this with specialist research-led
training in biophontonics, biomedical imaging
and instrumentation.

2010 Biomedical Science Handbook | 15


Courses
Year 1 courses 17
Year 2 courses 20
Year 3 suggested options 24
Course list 32
Postgraduate study in Biomedical Science 37
Programme contacts 38
Postgraduate courses 39

16 | 2010 Biomedical Science Handbook


Year 1 courses
BIOSCI 101 (15 points) BIOSCI 106 (15 points)
Essential Biology: From Genomes to Foundations of Biochemistry
Organisms Second Semester
First semester This course will consider biochemical reactions as
An introduction to the structures and processes essential elements of life processes. Material
which are common to micro-organisms, animals covered includes the molecular structure and
and plants at the cellular, molecular and actions of proteins, the synthesis and metabolism
biochemical levels. Genetic principles and of carbohydrates and fats in the fed and starved
processes and an overview of evolution and states, and elements of enzymology, metabolism,
evolutionary concepts are included. This course nutrition, vitamin, antibiotic action, and hormonal
includes guest lectures given by graduate control in health, physical performance and
students in research fileds relevant to course disease. Reference will be made to specific
content. biomedical examples where appropriate. This is a
limited entry course. Students are strongly
Coordinator: Ms Mandy Harper advised to complete BIOSCI 101 and CHEM 110
Email: a.harper@auckland.ac.nz before enrolling in BIOSCI 106. The enrolment
Assessment: In course 60% (theory 40%, process will involve selection based on a
practical 20%), Examination 40% minimum level of academic achievement.
Textbook: Biology, Campbell & Reese 2008
(Benjamin Cummings), 8th Ed. Coordinator: Mrs Libby Hitchings
Laboratory: 6 Laboratories (6 x 3 hours) Email: l.hitchings@auckland.ac.nz
Assessment: In course 60% (Theory 40%,
Note: This course assumes a knowledge of Year practical 20%), Examination 40%
13 Biology and at least Year 12 Chemistry. Textbook: Biochemistry (6th Edition).
Campbell and Farrell. (Thomson)
Laboratory: 6 Laboratories (6 x 3 hours)

2010 Biomedical Science Handbook | 17


BIOSCI 107 (15 points)
Biology for Biomedical Science: Cellular
Processes & Development
First Semester
The cellular and tissue level basis of mammalian
form and function. Special emphasis on cell
structure and processes including membrane
transport, muscle types and function, blood and
the immune response, and basic neurobiology.
Selected topics in human and experimental
embryology will also be covered. Practical
component includes labs on cell histology, human
embryology and muscle physiology. This is a
limited-entry course that assumes knowledge of
NCEA Level 3 Biology and at least Year 12
Chemistry.

Coordinator: Ms Mel Collings Notes:


Email: m.collings@auckland.ac.nz 1. Students not intending to apply for entry to
Assessment: In course 60% (Theory 40%, Medical School at the end of Year 1 and who
practical 20%), Examination 40% do not have a pass in Year 13 Chemistry are
Textbooks: Biology, Campbell & Reece, 8th ed. advised to take CHEM 150 prior to taking
(Benjamin Cummings) Principles of Anatomy & CHEM 110.
Physiology, Totora & Derrickson, 11th ed. (John
Wiley & Sons) 2. Students, other than those taking CHEM 150,
Laboratory: 6 Laboratories (6 x 3 hours) should take this paper in first semester.

CHEM 110 (15 points) MEDSCI 142 (15 points)


Chemistry of the Living World Biology for Biomedical Science: Organ
First Semester/ Second Semester Systems
A foundation for understanding the chemistry of Second semester
life is laid by exploring the diversity and reactivity Introduction to human biology with particular
of organic compounds. A systematic study of emphasis on integrated organ function. The
reactivity focuses on the site and mechanism of course will deal with: structures and processes
reaction including application of chemical associated with the function of the nervous,
kinetics. A quantitative study of proton transfer locomotor, cardiovascular, respiratory, digestive,
reactions features control of pH of fluids in both renal, endocrine and reproductive systems. This is
living systems and the environment. a limited entry course. The enrolment process will
involve selection based on a minimum level of
Coordinator: Dr Judy Brittain academic achievement.
Email: j.brittain@auckland.ac.nz
Assessment: In course 50% (2 one-hour tests Coordinators: Peter Riordan
30%; practical, including on-line modules, 20%), Email: p.riordan@auckland.ac.nz
Examination 50% Assessment: In course 40% (theory 28%, in-lab
Textbook: McMurry/Simanek (6th edition) or 12%), Examination 60%
McMurry (4th or 5th edition) “Fundamentals of Textbook: Tortora & Derrickson, Principles of
Organic Chemistry”. Anatomy and Physiology (11th Edition)
Laboratory: 6 Laboratories (6 x 3 hours) Laboratory: 6 Laboratories (6 x 2.5 hours)

18 | 2010 Biomedical Science Handbook


PHYSICS 160 (15 points) Elective
Physics for the Life Sciences Should ideally be chosen from biological sciences,
First semester / Second semester mathematics, statistics, physics, chemistry or
Designed for students intending to advance their other science courses.
studies in the life sciences. Students intending to
enrol in this course should have taken physics and If you intend to apply for medicine you must
mathematics to at least Level 2 NCEA. Topics include POPLHLTH 111 as your elective, and
covered will be especially relevant to biological complete an approved General Education
systems: mechanics, thermal physics, wave course.
motion, sound, light, electricity, physiology and
All Biomedical Science students must take 15
instrumentation.
points from an approved statistics course (any
Contact: Dr Frederique Vanholsbeeck statistics course, or BIOSCI 209).
Email: physics160@auckland.ac.nz
This may be completed at any time during the
Assessment: In course 40% (tests 15%, tutorials
programme.
5%, assignments 10%, labs 10%), examination
60%
Textbook: Urone, Paul, College Physics, 2nd
Edition (Brooks/Cole)
Laboratory: 4 Laboratories (4x3 hours)
Tutorials: 5 tutorials (5 x 2 hours)

2010 Biomedical Science Handbook | 19


Year 2 courses
In the second year, Biomedical Science students All students may complete under the 2010
will complete core courses in disciplines regulations if they so choose.
fundamental to biomedical science. These include
anatomy, biochemistry, cellular and molecular Course list
biology, genetics, microbiology, pathology,
pharmacology and physiology. BIOSCI 201 (15 points)
Cellular and Molecular Biology
First semester
The basic structure of biomolecules, the evolution
and structure of cells and their organisation into
tissues and organs are examined first. This is
followed by a study of the nucleus, the regulation
of gene expression, and DNA, RNA and protein
synthesis. Further sections deal with the cell
behaviour, development, cancer, and the basis of
immunity.

Prerequisite: BIOSCI 101, and 30 points from


BIOSCI 102-107, MEDSCI 142 and 15 points from
From 2010: CHEM 110, 120, 150.
Coordinator: Dr Ken Scott
Requirements for Year 2 students who
Email: k.scott@auckland.ac.nz
commenced the BSc-Biomedical Science
degree or any degree programme at The BIOSCI 202 (15 points)
University of Auckland between 2006-2008: Genetics
Second semester
• 30 points: BIOSCI 201 – 203
The basic principles of mutation, recombination
• 15 points: MEDSCI 205 and genetic mapping are established in this
course. These principles are developed in a
• At least 45 points: MEDSCI 201, 203, 204, variety of prokaryotic and eukaryptic organisms.
206, (BIOSCI 204 or MEDSCI 202), PSYCH Laboratory work uses molecular, microbial and
202. eukaryotic material to explore the key features of
heredity.
For students who commenced the BSc-
Biomedical Science degree or any degree Prerequisite: 30 points from Stage I Biological
programme at The University of Auckland in Sciences including BIOSCI 101
or after 2009, or before 2006: Coordinator: Associate Professor Brian Murray
Email: b.murray@auckland.ac.nz
• 45 points: BIOSCI 201 – 203

• MEDSCI 205

• At least 45 point: MEDSCI 201, 203, 204, 206,


(BIOSCI 204 or MEDSCI 202), PSYCH 202

20 | 2010 Biomedical Science Handbook


BIOSCI 203 (15 points) MEDSCI 202 (15 points)
Biochemistry Microbiology and Immunology
Second semester First semester
This course presents core areas of modern animal An introduction to the nature and roles of
and plant biochemistry. Emphasis is on bacteria, viruses, fungi and parasites as the
macromolecular (protein, enzyme and membrane) causative agents of human disease. The defence
structure and function, central metabolism, mechanisms of the body, the immune system
including metabolic integration and control, and including autoimmunity and allergy. Control of
signal transduction in hormone action and vision. disease by antimicrobials. Sterilisation,
Plant biochemistry includes nitrogen fixation, disinfection, and sterile manufacturing practice.
photosynthesis and cell wall structure.
Prerequisite: BIOSCI 107 and HUMANBIO 142
Prerequisite: BIOSCI 101, 106 and 15 points from or MEDSCI 142
either CHEM 110 or 120 Coordinator: Associate Professor Geoff
Coordinator: Associate Professor Tom Brittain Krissansen
Email: t.brittain@auckland.ac.nz Email: gw.krissansen@auckland.ac.nz

BIOSCI 204 (15 points) MEDSCI 203 (15 points)


Applied and Environmental Microbiology Mechanisms of Disease
First Semester First semester
Functions and behaviour of micro-organisms Outlines the basic mechanisms, operating at the
(prokaryotes, eukaryotes, and viruses) as individuals molecular, cellular and tissue levels, by which
and in communities. The fundamental role of human disease develops. These include genetic
micro-organisms in ecosystems. Application of factors, cell injury, inflammation, repair,
microbial capabilities to biotechnology, food circulatory disturbances, and neoplastic change.
production, agriculture and industry. Methods for These mechanisms are illustrated by descriptions
the isolation, culture, and study of micro-organisms. of the pathogenesis of specific diseases that are
relevant to the New Zealand situation, or are the
Prerequisites: BIOSCI 101 and at least 15 points focus of current biomedical research.
from BIOSCI 102, BIOSCI 106, BIOSCI 107.
Coordinator: TBA Prerequisites: BIOSCI 107 and HUMANBIO 142
Email: TBA or MEDSCI 142
Restriction: PATHOL 251
MEDSCI 201 (15 points) Coordinator: Dr Graeme Finlay
Human Structure and Function Email: g.finlay@auckland.ac.nz
First Semester
Presents the structure of biological systems with MEDSCI 204 (15 points)
special reference to human biology, from the levels Introduction to Pharmacology and
of histology through to gross anatomy. Specific Toxicology
examples of the correlation between structure and Second Semester
function will be considered. An introduction to A solid grounding in the principles underlying
current techniques for the visualisation of biological pharmacology and toxicology, including the
structure will be presented. nature of drug targets, their interaction and
response (pharmacodynamics), the fate of drugs
Prerequisite: BIOSCI 107 and HUMANBIO 142 or within the body (pharmacokinetics), toxicity
MEDSCI 142 classification and testing, poisons and antidotes,
Coordinator: Peter Riordan adverse drug reactions, selective toxicity, drug
Email: p.riordan@auckland.ac.nz discovery and development. Selected drug

2010 Biomedical Science Handbook | 21


MEDSCI 206 (15 points)
Introduction to Neuroscience
Second Semester
The impact of neuroscience revolution on our
understanding of human physiology and
biomedical research is reviewed. Topics include:
mechanisms of neurotransmission, learning,
memory, sensory perception (vision, hearing,
touch and smell) and application of gene therapy
for treating neurological diseases. Special
emphasis is placed on the integration and control
of physiological function by the nervous system.
Examples include control of movement and
coordination, regulation of reproduction, blood
pressure, breathing, appetite, body weight and
sexuality. Developmental neuroscience is also
examples will be studied to illustrate key considered. Laboratory exercises provide insight
principles of clinical pharmacology. into neural structure and function and include
application of neuroimaging technologies.
Restriction: PHARMCOL 201
Coordinator: Dr Debbie Young Prerequisite: BIOSCI 107 and HUMANBIO 142
Email: ds.young@auckland.ac.nz or MEDSCI 142
Restriction: PHYSIOL 220
MEDSCI 205 (15 points)
Coordinator: Dr Johanna Montgomery
The Physiology of Human Organ Systems
Email: physiology@auckland.ac.nz
First semester
An integrative approach is used to study PSYCH 202 (15 points)
fundamental physiological processes which Biopsychology
enable the body to overcome the challenge of life. First semester
Drawing on examples of normal and abnormal Provides a basic introduction to the structure and
function, the course examines the interaction of function of the brain, neuropsychology, and
vital physiological processes, from cellular control genetic and hormonal influences on behaviour.
mechanisms to multiple organ systems. Topics This course includes a compulsory laboratory
include: control of fluid and electrolytes, component.
cardiovascular control, energy use, and the
delivery of oxygen and metabolites. Prerequisite: 30 points in Stage I Psychology or
15 points from BIOSCI 101, 103
Prerequisite: BIOSCI 107 and HUMANBIO 142 Restriction: 461.230
or MEDSCI 142 Coordinator: Associate Professor Ian Kirk
Restriction: PHYSIOL 210 Email: i.kirk@auckland.ac.nz
Coordinator: Dr Marie Ward
Email: m.ward@auckland.ac.nz

22 | 2010 Biomedical Science Handbook


Preparation for Year 3 Options
If you choose to follow the ‘Option’ structure for the third year, the Stage II courses listed below will
ensure you have met all prerequisites for courses recommended for that option.
Note that if you vary your choices different prerequisites may be required.

Cancer Biology & Cardiovascular Biology Cellular & Molecular Genetics &
Therapeutics Biomedicine Development

Recommended: Recommended: Recommended: Recommended:

MEDSCI 205 MEDSCI 205 MEDSCI 205 MEDSCI 205


BIOSCI 201 BIOSCI 201 BIOSCI 201 BIOSCI 201
BIOSCI 202 BIOSCI 202 BIOSCI 202 BIOSCI 202
BIOSCI 203 BIOSCI 203 BIOSCI 203 BIOSCI 203
MEDSCI 203 MEDSCI 206
MEDSCI 204
Desirable : Desirable : Desirable : Desirable :

MEDSCI 201 MEDSCI 203 MEDSCI 203


MEDSCI 204
MEDSCI 206
Microbiology & Neurobiology Nutrition Reproduction, Growth
Immunology & Metabolism

Recommended: Recommended: Recommended: Recommended:

MEDSCI 205 MEDSCI 205 MEDSCI 205 MEDSCI 205


BIOSCI 201 BIOSCI 201 BIOSCI 201 BIOSCI 201
BIOSCI 202 BIOSCI 202 BIOSCI 202 BIOSCI 202
BIOSCI 203 BIOSCI 203 BIOSCI 203 BIOSCI 203
[BIOSCI 204 or MEDSCI 204
MEDSCI 202] MEDSCI 206
MEDSCI 203
Desirable : Desirable : Desirable : Desirable :

MEDSCI 201 MEDSCI 203, 204, 206 MEDSCI 201


or PSYCH 202 (MEDSCI 202 or BIOSCI MEDSCI 203
204)
Note: All students must complete two General Education and one statistics courses at some time
during Years 1, 2 or 3

2010 Biomedical Science Handbook | 23


Year 3 suggested options
In Year 3 students select from one of the following DNA damage and to inhibition of growth
options: signalling pathways. Research includes both
molecular and cellular approaches, and
Cancer Biology and Therapeutics includes work on the properties of cancer cells
grown from tissue donated by cancer patients.
Cancer affects over a quarter of the world’s
population and its control and cure provide • Research on cancer causation includes studies
considerable challenges for research. Progress of mutagenesis by dietary and chemical
over last four decades has resulted in an carcinogens and the development of new
improved understanding of the disease and the strategies for preventing cancer, particularly
formulation of novel strategies for prevention and those involving modulation of dietary
cure. A number of groups in the University are components.
involved in research projects in cancer, and the
establishment of the Auckland Cancer Society • Research in cancer therapeutics includes the
Research Centre (ACSRC) in the Faculty of design, synthesis and evaluation of new types
Medical and Health Science has now provided a of anticancer drugs. Emphasis is placed on
strong focus for a multidisciplinary research drug pharmacokinetics since this has close
programme. The international successes of the connections with clinical trials of new
ACSRC include the development of five drugs anticancer drugs developed by the ACSRC.
from the design stage through to clinical trials in Further research areas include the delivery
cancer patients. This background provides a drugs to targets within the tumour, the
number of opportunities for research projects activation of prodrugs within tumours,
with a high degree of relevance to human cancer. interactions between drugs and radiotherapy,
and the tumour microenvironment. The latter
Current research can be divided into three includes studies on the role of both vascular
interlinking areas: and immune components in the action of new
anticancer drugs.
• Research in cancer biology includes studies on
the genetics and cell biology of cancer growth, For further information or advice contact:
and studies of responses of cancer cells to Dr Nuala Helsby
School of Medical Sciences
Phone: 373 7599 ext 89831
Email: n.helsby@auckland.ac.nz

Requirements for students who have been


enrolled in the BSc-Biomedical Science
degree or any degree programme at The
University of Auckland prior to 2006:

• at least 15 points from PATHOL 302, MEDSCI


302

• at least 45 points from BIOSCI 351, 353, 354,


356-358, CHEM 390, 392, MEDSCI 303, 306,
314, PHARMCOL 301, 303, 305

24 | 2010 Biomedical Science Handbook


• at least 45 further points from courses listed in patent attorneys, biotechnology companies,
the Bachelor of Science schedule. A total of 90 hospitals.
points above Stage II must be taken by
students applying for Honours. For further information and advice contact:
Associate Professor Laura Bennet
Recommended course of study for students School of Medical Sciences
who have been enrolled in the BSc- Phone: 373 7599 ext 84890
Biomedical Science degree or any degree Email: l.bennet@auckland.ac.nz
programme at The University of Auckland
after 2005: Requirements for students who have been
enrolled in the BSc-Biomedical Science
• MEDSCI 301-303 degree or any degree programme at The
University of Auckland prior to 2006:
• At least 30 points from BIOSCI 351, 353, 354,
356, 358, CHEM 390, 392, MEDSCI 306, 314 • at least 30 points from MEDSCI 308, 311,
PHYSIOL 301, 304
• At least 45 further points chosen from the
Bachelor of Science schedule. A total of 90 • at least 15 points from MEDSCI 301, 305, 309,
points above Stage II must be taken by 310, PATHOL 301, PHARMCOL 304, PHYSIOL
students applying for Honours 302

• at least 15 points from BIOSCI 350, 351, 353,


Cardiovascular Biology
354
Imagine a single cardiac muscle cell contracting,
which in combination with other cells forms the • at least 45 further points from courses listed in
heart, whose rhythm and function is regulated by the Bachelor of Science schedule. A total of 90
the central nervous system to give rise to, along points above Stage II must be taken by
with blood vessel tone, blood pressure, and you students applying for Honours.
have an essence of the breadth of cardiovascular
research covered within The University of Recommended course of study for students
Auckland. Cardiovascular disease kills 50% of the who have been enrolled in the BSc-
population and is a major area of health and Biomedical Science degree or any degree
research expenditure worldwide. The University programme at The University of Auckland
of Auckland contains the largest and most after 2005:
respected grouping of cardiovascular researchers
in New Zealand. Research undertaken is well • MEDSCI 308, 309, 311
funded and has an international reputation.
• At least 30 points from MEDSCI 301, 305, 310,
Students choosing cardiovascular biology have
BIOSCI 350, 351, 353, 354
an enormous range of research laboratories to
choose from including molecular and cellular • At least 45 further points chosen from the
issues relating to cardiac muscle cells and blood Bachelor of Science schedule. A total of 90
vessels, to heart structure and function, to control points above Stage II must be taken by
of blood pressure and even human students applying for Honours
cardiovascular studies. Thus wherever your
interests lie there is something for you. There is Cellular and Molecular Biomedicine
large demand for graduates in cardiovascular
biology in such varied employment areas as; The primary objective of biomedical research is to
drug development, pharmaceutical sales, understand biological processes in normal and
fundamental research, teaching, clinical research, diseased tissues at the cellular and molecular

2010 Biomedical Science Handbook | 25


level. The Cellular and Molecular Biomedicine • at least 45 points from BIOSCI 350, 351, 353
option offers students a chance to focus their
study at a fundamental level and apply it to the • at least 15 points from MEDSCI 304, 308,
widest possible range of biomedical research 309, PHARMCOL 302, PHYSIOL 301, 302
themes. The emphasis is on how basic studies in
• at least 45 further points from courses listed in
molecular and cellular biology contribute to the
the Bachelor of Science schedule. A total of 90
development of knowledge in a variety of
points above Stage II must be taken by
biomedical fields. Students will gain first-hand
students applying for Honours
experience in the application of state-of-the art
technologies including genomics and proteomics, Recommended course of study for students
biomolecular structure analysis, cellular imaging who have been enrolled in the BSc-
and electrophysiology. Biomedical Science degree or any degree
programme at The University of Auckland
Research interests of affiliated staff cover gene
after 2005:
structure and expression, molecular cell biology
and the structure and function of biomolecules as • BIOSCI 350, 351, 353
applied to molecular neuroendocrinology,
metabolic regulation, diabetes and insulin • At least 30 points from MEDSCI 301, 303-305,
resistance, molecular virology, membrane 308, 309
transport, cellular physiology and drug
development. • At least 45 further points chosen from the
Bachelor of Science schedule. A total of 90
Fourth year studies for the Cellular and points above Stage II must be taken by
Molecular Biomedicine option could include students applying for Honours
courses that cover techniques in genomics,
proteomics and bioinformatics, the application of Genetics and Development
transgenic methods to the biomedical industry,
current themes in biomedical research, Developmental biology is concerned with how
biomolecular structure and function or multicellular organisms and their complex
applications of recombinant DNA technology to structures such as different organs and tissues
biomedicine. arise from a single cell. Much of the excitement
in developmental biology today arises from our
For further information contact: growing understanding of how genes direct these
Dr Judy O’Brien developmental processes.
School of Biological Sciences
Phone: 373 7599 ext 88764 This option will explore how cells interact to build
Email: j.obrien@auckland.ac.nz organisms and how the structure of organisms is
influenced by the genome. There is reason to
Associate Professor Paul Donaldson believe that the extraordinary complexity of an
Department of Optometry and Vision Science adult organism is the product of a set of
Phone: 373 7599 ext 84625 somewhat simpler programmes, set in place
Email: p.donaldson@auckland.ac.nz during development. Many of these genetic
programmes are accessible to researchers
Requirements for students who have been through model systems that are less complex
enrolled in the BSc-Biomedical Science than humans. Basic regulatory and
degree or any degree programme at The developmental pathways are remarkably
University of Auckland prior to 2006: conserved among diverse organisms (fruit fly,
nematode worm, zebrafish, frogs, mice, humans).

26 | 2010 Biomedical Science Handbook


The completion of the human genome sequence,
together with the sequencing of the genomes of
several other model organisms, has
demonstrated the extraordinary similarities
between the genomes of humans and those of
simpler organisms. The sequences provide
further evidence that the study of genetic
pathways in these simpler organisms, where work
can be done more rapidly, provides fundamental
knowledge directly applicable to the study of
human genetics and disease. Many
computational tools that comprise the area of • at least 45 further points from courses listed in
bioinformatics are used widely in development the Bachelor of Science schedule. A total of 90
and genetics. points above Stage II must be taken by
students applying for Honours.
In summary, reference will be made to many
model organisms in this option and you will learn Recommended course of study for students
how genes influence development by focussing on who have been enrolled in the BSc-
specific organs and tissues. We will also consider Biomedical Science degree or any degree
how problems in development underpin many programme at The University of Auckland
diseases of the human body. Research in all after 2005:
areas of biomedicine require an appreciation of
• 45 points from BIOSCI 351, 354, 356
the temporal and spatial patterns of gene
expression, and developmental programmes. It is • At least 30 points from BIOSCI 350, 353,
these areas that are highlighted in the Genetics MEDSCI 301, 312
and Development option.
• At least 45 further points chosen from the
For further information or advice contact: Bachelor of Science schedule. A total of 90
Associate Professor Phil Crosier points above Stage II must be taken by
School of Medical Sciences students applying for Honours
Phone: 373 7599 ext 86279
Email: ps.crosier@auckland.ac.nz
Microbiology and Immunology
Associate Professor Don Love The course of infectious disease in humans is
School of Biological Sciences determined by the replication and spread of
Phone: 373 7599 ext 87228 microbial pathogens on the one hand and the
Email: d.love@auckland.ac.nz ability of the host immune system to recognise
and eliminate these invaders on the other.
Requirements for students who have been Outcomes of these competing processes are
enrolled in the BSc-Biomedical Science determined through the spectrum of molecular
degree or any degree programme at The interactions made between the host and invading
University of Auckland prior to 2006: pathogen. Thus the Microbiology and
Immunology option integrates two of the most
• 45 points from BIOSCI 351, 354, 356
active areas of biomedical research: the
• at least 30 points from BIOSCI 350, 353, molecular microbiology of bacteria, viruses and
MEDSCI 301 microbial eukaryotes together with the nature
and complexity of the immune response triggered
by their infection of animal hosts. The overall

2010 Biomedical Science Handbook | 27


objective is to give students an insight into the
interactions between pathogens and host at the
molecular level and to provide a view of the
human immune system as both an effective
barrier to disease and the major driving force
behind microbial evolution.

Course material will focus on major current


themes in molecular microbiology with emphasis
on signalling within microbial communities,
analysis of microbial genomes, the structural
biology of microbes and the molecular basis of
microbial pathogenesis. A medical perspective is
also included that addresses how bacteria
perceive and respond to the host environment as
well as the emergence of novel pathogenic
microbes, the re-emergence of old ones and the
Requirements for students who have been
problem of antibiotic resistance. From the
enrolled in the BSc-Biomedical Science
immune system perspective this option will focus
degree or any degree programme at The
on the diversity and regulation of host processes
University of Auckland prior to 2006:
that are active during various infections, the
genes and proteins involved in innate and • at least 45 points from BIOSCI 349, 352, 357,
adaptive immunity, and how the immune system MEDSCI 301, 314
distinguishes self from non-self. Links between
the immune and nervous systems and how these • at least 30 points from BIOSCI 350-353
influence physiological and behavioural responses
to infection are also covered. • at least 45 further points from courses listed in
the Bachelor of Science schedule. A total of 90
Research groups are active in the Faculty of points above Stage II must be taken by
Medical and Health Sciences and the School of students applying for Honours.
Biological Sciences, providing many exciting
opportunities for postgraduate research projects Recommended coures of study for students
in this area. who have been enrolled in the BSc-
Biomedical Science degree or any degree
For more information contact option programme at The University of Auckland
Coordinators; after 2005:

Associate Professor Roger Booth • 45 points from BIOSCI 349, 357, MEDSCI 301,
School of Medical Sciences 314
Phone: 373 7599 ext 86475
Email: rj.booth@auckland.ac.nz • At least 30 points from BIOSCI 347, 348,
350-353
Dr. John Taylor
School of Biological Sciences • At least 45 further points chosen from the
Phone: 373 7599 ext 82854 Bachelor of Science schedule. A total of 90
Email: ja.taylor@auckland.ac.nz points above Stage 2 must be taken by
students applying for Honours

28 | 2010 Biomedical Science Handbook


Neurobiology
Neurobiology is one of the fastest growing areas
of modern biomedical science. Research in this
field deals with structures and mechanisms that
underlie the function of the brain and nervous
system in health and disease. The approaches
used are interdisciplinary and integrate
knowledge from the level of the molecule to that
of the most complex neural systems.

Neurobiology is an area in which The University


of Auckland is particularly strong with numerous
research groups acknowledged as world leaders
in their fields. Multi-disciplinary teams in the
School of Medical and Health Science are Requirements for students who have been
working on the development of the nervous enrolled in the BSc-Biomedical Science
system, the cellular basis of learning and degree or any degree programme at The
behaviour, mechanisms of hearing and vision, University of Auckland prior to 2006:
control of breathing and circulation by the central
• at least 45 points from MEDSCI 307, 308, 310,
nervous system, regulation of feeding behaviour
PHARMCOL 306, PHYSIOL 301, 303
and body weight; and the molecular and cellular
basis of neuro degenerative brain disorders such • at least 30 points from BIOSCI 350, 351, 353,
as Alzheimer’s, Huntington’s and Parkinson’s 354, MEDSCI 309, PHYSIOL 302, PSYCH 305
disease and on stem cell repair in these
disorders. These groups employ techniques • at least 45 further points from courses listed in
ranging through molecular biology, biophysics, the Bachelor of Science schedule. A total of 90
neuroanatomy, neurophysiology, gene therapy points above Stage II must be taken by
and a range of modern imaging methods. students applying for Honours.
Functional brain imaging is being used to
investigate aspects of cognition and behaviour in Recommended course of study for students
the Department of Psychology, while computer who have been enrolled in the BSc-
modelling and neurophysiology are being Biomedical Science degree or any degree
combined in the School of Biological Sciences to programme at The University of Auckland
study the role of the cerebellum in the after 2005:
coordination and control of movement.
• 45 points: MEDSCI 304, 307, 308, 310
Biomedical Science students who are interested
in specialising in this option should select • At least 30 points from BIOSCI 350, 351, 353,
MEDSCI 205 and 206 and may wish to include 354, MEDSCI 309, 312, PSYCH 305
MEDSCI 201 and PSYCH 202.
• At least 45 further points chosen from the
For further information contact: Bachelor of Science schedule. A total of 90
Dr Johanna Montgomery points above Stage II must be taken by
Department of Physiology students applying for Honours
Phone: 373 7599 ext 89828
Email: jm.montgomery@auckland.ac.nz

2010 Biomedical Science Handbook | 29


Nutrition utero and in early infancy. They subsequently affect
Nutrition is central to the maintenance of good morbidity, physical and mental capacity throughout
health, and fundamental to biomedical science. life, and the development of diet-related disease.
While nutrients were traditionally considered Although most effectively addressed during
necessary for preventing deficiency diseases, it is interuterine development, nutritional intervention
increasingly clear that inappropriate diet may be throughout life may overcome these genetic and/or
responsible for almost half of the global burden of epigenetic-related susceptibilities. Studies in these
Non Communicable Diseases, as well as areas are done through the Department of
significantly enhancing susceptibility to Pediatrics and also The Liggins Institute.
Communicable Diseases. More generally, “chronic
While human population monitoring or dietary
disease” related to diet covers a range of disorders
intervention studies are done by several groups,
including abdominal obesity, diabetes,
the Human Nutrition Unit provides a well-
cardiovascular disease (cvd), certain cancers,
maintained human metabolic unit that permits
osteoporosis, arthritis, and inflammatory disease.
highly controlled clinical trials in a live-in situation.
There is a considerable nutrition-related skill base
across The University of Auckland, both in the For further information or advice contact:
Faculty of Medical and Health Sciences and in the Professor Lynn Ferguson
School of Biological Sciences which also directs the School of Medical Sciences
Human Nutrition Trial Unit in Mt Eden, with Phone: 373 7599 ext. 86372
several groups focused on different research areas Email: l.ferguson@auckland.ac.nz
ranging from molecular nutrition through to
population-based studies, and also including Recommended course of study
clinically related examples. The three papers that
form the focus of the third year requirements cover • 45 points from BIOSCI 358, MEDSCI 312, 315
a range of topics in nutrition and metabolism, the
• At least 30 points from BIOSCI 348, 351, 353,
role of nutrients in signal transduction and the
FOODSCI 301, MEDSCI 301, 306-308, 314
exciting new field of nutritional genomics (or
nutrigenomics). • At least 45 further points from courses listed in
the Bachelor of Science schedule. A total of 90
Nutritional genomics considers the influence of the
points above Stage II must be taken by students
genome on nutrition, and has the potential to
applying for Honours.
provide tailored nutritional advice to populations
groups or to individuals. It recognises that what is Note: Students should note that FOODSCI 201
appropriate dietary advice for one individual may is a prerequisite for FOODSCI 301.
be inappropriate, or actually harmful, to another.
Learning how to understand this interaction at the
Reproduction, Growth and Metabolism
molecular level, and to apply it in animal studies
or at a population level, is the rationale behind the You may not have thought about it yet, but it is
major FRST-funded programme, Nutrigenomics likely that you believe that when the time is right
New Zealand, which is run through the School of you will choose to have children and that they will
Medical Sciences (in association with other be normal and healthy. This is everyone’s
University of Auckland departments, and three expectation. Unfortunately, for 1 in 6 couples
Crown Research Institutes). infertility, miscarriages and other diseases of
pregnancy prevent this expectation from coming to
Both maternal nutrition (during pregnancy and fruition. And then one in five children resulting
breastfeeding), and genetic factors, have profound from successful pregnancies will develop obesity,
influences on development and growth, both in diabetes and health related complications as the

30 | 2010 Biomedical Science Handbook


grow through puberty into adulthood. In the RGM obesity, diabetes, bone and thyroid diseases and
option you will learn about reproduction in humans cancer. Staff from AgReseach, Ruakura
and animals. You will learn about the normal (Hamilton) are involved in this option. You will
development of humans from before the first visit Ruakura, and the exciting possibility exists to
twinkle in mum and dad’s eyes, through carry out research in New Zealand’s leading
development of the embryo/fetus in the uterus. animal reproduction group.
You will find how life in utero is different to life as
we know it –how does a fetus eat and breathe? For further information and advice contact:
Learn how the fetus controls mum! You will Associate Professor Larry Chamley
discover the problems that may be encountered in School of Medicine
utero and how we are working to overcome these. Email: l.chamley@auckland.ac.nz

Reproduction is intimately associated with growth Associate Professor Andrew Shelling


and metabolism. Impaired gonad function, obesity School of Medicine
and metabolic syndrome commonly occur together. Phone: 373 7599 ext 83504
Females require a certain level of fat reserves to Email: a.shelling@auckland.ac.nz
initiate puberty and to reproduce. Obesity in
women on the other hand, has a negative impact Requirements for students who have been
upon reproduction. Similarly, maintenance of a enrolled in the BSc-Biomedical Science
healthy body weight is necessary for optimal male degree or any degree programme at The
reproductive health. You will learn about University of Auckland prior to 2006:
hormones, growth factors, and cell signalling
• at least 45 points from BIOSCI 351, MEDSCI
mechanisms that allow the fetus to grow and
312, 313, OBSTGYN 351, PHYSIOL 305
develop into an adult. While some of us will
maintain a healthy weight into adulthood, others • at least 15 points from BIOSCI 350, 353, 354,
will be predisposed to developing metabolic 356-358, MEDSCI 301, 314
diseases, obesity, diabetes and metabolic
syndrome. You will learn how hormones and • at least 45 further points from courses listed in
growth factors regulate metabolism and what goes the Bachelor of Science schedule. A total of 90
wrong when metabolic diseases develop. points above Stage II must be taken by
students applying for Honours.
The University of Auckland has a long tradition of
excellence in reproductive science, growth and Recommended course of study for students
metabolism that continues today. Research groups who have been enrolled in the BSc-
in the Department of Obstetrics and Gynaecology Biomedical Science degree or any degree
and Liggins Institute focus on fertility/infertility, programme at The University of Auckland
ovarian function and failure, reproductive cancers, after 2005:
preterm birth, fetal development, protection of the
newborn from brain injury, and the causes of • MEDSCI 312, 313, BIOSCI 351
miscarriages and other diseases of pregnancy.
Research groups in the Department of Physiology, • At least 30 points from BIOSCI 350, 353, 354,
Molecular Medicine and Pathology and 356, 358, MEDSCI 301, 314
Department of Medicine focus on hormones,
• At least 45 further points chosen from the
growth factors and cell signalling mechanisms
Bachelor of Science schedule. A total of 90
involved in growth and development of the fetus
points above Stage II must be taken by
and into adulthood, and variations and
students applying for Honours
abnormalities in these hormonal and growth factor
signalling pathways that result in overweight,

2010 Biomedical Science Handbook | 31


Course list vaccination. Use of microorganisms in medical
biotechnology.
BIOSCI 347 S2 C (15 points)
Environmental Microbiology and Prerequisite: BIOSCI 204 or MOLMED 201 or
Biotechnology MEDSCI 202
The ecology and physiology of microorganisms in Coordinator: Dr John Taylor
natural and engineered environments. Key Email: ja.taylor@auckland.ac.nz
themes include marine microbiology, the
importance of microbial symbioses to life on BIOSCI 350 S1 C (15 points)
Earth, and contemporary research methods in Protein Structure and Function
microbiology. Processes such as wastewater The relationship of molecular structure to protein
treatment and the production of bioactives are function will be emphasised. Techniques for the
used to emphasise exploitation of microbial purification, characterisation and production of
metabolism for environmental biotechnology native and recombinant proteins and three-
purposes. dimensional structure determination will be
combined with a description of protein structure.
Prerequisite: 15 points from BIOSCI 204, Specific groups of proteins will be selected to
MOLMED 201, MEDSCI 202 illustrate structure/function relationships and
Restriction: BIOSCI 352 protein evolution.
Coordinator: Dr Mike Taylor
Email: mw.taylor@auckland.ac.nz Prerequisite: BIOSCI 201 and 203
Coordinator: Associate Professor David Christie
BIOSCI 348 S2 C (15 points) Email: d.christie@auckland.ac.nz
Food and Beverage Microbiology
The use and scientific fundamentals of BIOSCI 351 S1 C (15 points)
microorganisms in the production of foods and Molecular Genetics
food additives, nutriceuticals and probiotics. The analysis of genetic material in prokaryotes,
Molecular and applied aspects of the viruses, yeast, plants and humans is addressed.
fermentation processes for beer and wine The means by which genetic information is
including aroma generation and analysis. transferred and the mechanisms underlying
Microbial food spoilage, pathogens involved, food genome diversity will be examined, together with
safety and quality control. the study of eukaryote genomes at the level of
chromosome structure and organisation. The
Prerequisite: 15 points from BIOSCI 204, molecular mechanisms underpinning selected
MOLMED 201, MEDSCI 202 inherited human disorders will be discussed as
Restriction: BIOSCI 352 well as the role of model species in understanding
Coordinator: Dr Silas Villas-Boas normal and perturbed biological pathways.
Email: s.villas-boas@auckland.ac.nz
Prerequisite: BIOSCI 201, 202
BIOSCI 349 S1 (15 points) Coordinator: Associate Professor Brian Murray
Biomedical Microbiology Email: b.murray@auckland.ac.nz
The major biochemical, physiological and genetic
systems involved in the biology of microorganisms BIOSCI 353 S2 C (15 points)
affecting human health. Properties of Molecular and Cellular Regulation
microorganisms important in pathogenesis and The molecular mechanisms which mediate
virulence, and examples of infectious diseases. intracellular sorting and targeting of biologically
The molecular response of the host cells during active molecules and the networks of intracellular
infection. The molecular basis for antimicrobial and extracellular signals which regulate cell
therapy, acquisition of resistance, and function form the focus of this course. The roles of

32 | 2010 Biomedical Science Handbook


growth factors, oncogenes, plasma membrane covered in an integrated manner. The
receptors, nuclear receptors, ion channels and methodologies which underpin nutritional science
membrane transporters are emphasised. and its applications are included. Reference will be
made to a broad range of examples, and a number
Prerequisite: BIOSCI 201 and 203 of specific nutritional topics of current interest will
Coordinator: Associate Professor Nigel Birch also be included.
Email: n.birch@auckland.ac.nz
Prerequisite: BIOSCI 203
BIOSCI 354 S2 C (15 points) Coordinator: Associate Professor Sally Poppitt
Gene Expression and Gene Transfer Email: s.poppitt@auckland.ac.nz
Molecular biology of plant and animal cells is
stressed in topics covering gene expression and CHEM 390 S1 C (15 points)
genetic engineering. These include methods of Medicinal Chemistry
gene isolation, transcription factors and the Nature of cellular targets for drug action - lipids,
control of gene expression, animal viruses as proteins, enzymes, DNA. Principles of molecular
gene vectors, gene therapy in humans, genetic recognition. Enzymes and receptors are targets for
engineering of livestock, methods of gene transfer drug action, DNA as a target for drug action. An
in plants and examples of genetic engineering for overview of approaches to drug discovery and
crop improvement. development. Structure-activity relationships,
stereochemistry and drug action, prodrugs, drug
Prerequisite: BIOSCI 202 and either BIOSCI 201 solubilisation and delivery, drug metabolism, and
or 203 or 205 antibiotic resistance. Laboratories focus on the
Coordinator: Associate Professor Joanna synthesis, computer modelling and biological
Putterill testing of drugs.
Email: j.putterill@auckland.ac.nz
Prerequisite: No formal prerequisite, but
BIOSCI 356 S1 C (15 points) knowledge of organic chemistry and laboratory
Developmental Biology and Cancer practice at the level covered in CHEM 230 or
Molecular, cellular and genetic aspects of normal CHEM 203 will be assumed.
and abnormal development focusing on a variety Restriction: CHEM 309
of model systems including Drosophila, the Coordinator: Dr Vijayalekshmi Sarojini Amma
zebrafish and the mouse. Molecular events Email: v.sarojini@auckland.ac.nz
underlying the development of body form, the
differentiation of specific tissues such as the CHEM 392 S2 C (15 points)
blood, and abnormalities of development which Issues in Drug Design and Development
contribute to diseases of the body such as cancer. Intellectual property and patent law in the
Implications of transgenic techniques on pharmaceutical industry. An overview of the legal
development. and regulatory framework for drug design and
development. Clinical trials: formulation of a drug;
Prerequisite: BIOSCI 201 and 202 phase I, phase II and phase III protocols. An
Coordinator: Dr Lorna Johnstone introduction to the principles involved in the Codes
Email:ls.johnstone@auckland.ac.nz of Good Manufacturing Practice and Good
Laboratory Practice (quality control and quality
BIOSCI 358 S2 C (15 points)
assurance procedures) as applied to the
Nutritional Science
manufacture of drug products and the
The scientific basis of nutrition focusing on its
quantification of drugs and metabolites in biological
biochemistry and physiology in health and
fluids. Examples of drug development case studies
disease. Nutritional aspects of carbohydrates,
of selected drugs from design to release.
fats, proteins, vitamins and trace nutrients are

2010 Biomedical Science Handbook | 33


Coordinator: Dr Vijayalekshmi Sarojini Amma MEDSCI 303 S1 H (15 points)
Email: v.sarojini@auckland.ac.nz Principles of Pharmacology
Topics covered are: ADME and pharmacokinetics;
FOODSCI 301 S1 C (15 points) therapeutic drug monitoring; drug-drug
Food Quality Attributes interactions; pharmacogenetics and
Attributes that make food attractive, such as pharmacogenomics; drug development and
colour, flavour, and texture, and how they alter analysis; novel drug delivery, chemotherapy
during processing are studied. Texture including antibiotics, anticancer and antiviral
measurement and methods of studying food drugs.
structure will be discussed. Lectures will be given
on non-destructive testing of food. Prerequisite: PHARMCOL 201 or MEDSCI 204
and (PHYSIOL 210 or PHYSIOL 220 or BIOSCI
Recommended preparation: BIOSCI 203 and 203 or MEDSCI 205 or MEDSCI 206)
204 Restriction: PHARMCOL 301
Prerequisite: FOODSCI 201 Coordinator: Associate Professor James Paxton
Coordinator: Dr Bronwen Smith Email: j.paxton@auckland.ac.nz
Email: b.smith@auckland.ac.nz
MEDSCI 304 S1 H (15 points)
MEDSCI 301 S2 H (15 points) Molecular Pharmacology
Molecular Basis of Disease Considers the molecular mechanisms of drug
An in-depth analysis of the cellular and molecular action. The cellular and molecular mechanisms
basis of disease, including the role of of drugs acting at receptors, ion channels,
environmental and inherited risk factors, as well enzymes and intermediate messengers are
as mechanisms of response to cell injury and covered. These concepts are applied through a
inflammation in the disease process. Models of detailed examination of cell cycle and apoptotic
common diseases such as diabetes, obesity, pathways, the molecular basis of drug addiction
cancer and infectious agents will be studied. and the mechanisms of action of common
recreational drugs.
Prerequisite: PATHOL 251 or MEDSCI 203
Restriction: PATHOL 301 Prerequisite: PHARMCOL 201 or MEDSCI 204
Coordinator: Dr Nuala Helsby and (PHYSIOL 210 or PHYSIOL 220 or BIOSCI
Email: n.helsby@auckland.ac.nz 203 or MEDSCI 205 or MEDSCI 206)
Restriction: PHARMCOL 302
MEDSCI 302 S2 H (15 points)
Coordinator: Associate Professor Michelle Glass
Cancer Biology
Email: m.glass@auckland.ac.nz
A study of the scientific basis of cancer including:
mechanisms underlying the pathogenesis of MEDSCI 305 S2 H (15 points)
cancer, carcinogenesis, DNA damage and repair, Systematic Pharmacology
properties of cancer cells (including abnormalities Considers the modification by drugs of human
of growth and cell cycle control), the growth of systems under physiological and pathological
tumors, the classification and histopathology of conditions. The cellular and molecular
cancers, and an introduction to therapeutic mechanisms of drugs as receptors, ion channels,
strategies. enzymes and intermediate messengers are
considered. The modification of drugs on the
Prerequisite: BIOSCI 356 or PATHOL 251 or
cardiovascular, gastrointestinal, endocrine,
MEDSCI 203
reproductive, respiratory and central nervous
Restriction: PATHOL 705 or MEDSCI 714
systems will be covered.
Coordinator: Dr Maggie Kalev
Email: m.kalev@auckland.ac.nz

34 | 2010 Biomedical Science Handbook


Prerequisite: PHARMCOL 201 or MEDSCI 204 MEDSCI 307 S1 H (15 points)
and (PHYSIOL 210 or PHYSIOL 220 or BIOSCI Neuroscience: Neuropharmacology
203 or MEDSCI 205 or MEDSCI 206) An introduction to the principles and concepts
Restriction: PHARMCOL 304 involved in neuropharmacology. The course
Coordinator: Associate Professor Bronwen covers: the anatomy, neurochemistry and
Connor pharmacology of the normal and diseased
Email: b.connor@auckland.ac.nz human brain; the biochemical causes of
psychiatric and neurological diseases; and the
MEDSCI 306 S2 H (15 points) types and mechanisms of action of drugs used to
Principles of Toxicology treat brain disorders.
Considers the principles and concepts that result
in detrimental effects in animals and humans. It Prerequisite: PHARMCOL 201 or MEDSCI 204
addresses: biochemical pathways and targets in and (PHYSIOL 210 or PHYSIOL 220 or BIOSCI
the toxicity of chemicals, the effects at cellular, 203 or MEDSCI 205 or MEDSCI 206)
organ and whole body level, e.g. cell death, Restriction: PHARMCOL 306
cancer and hypersensitivity, as well as the basis Coordinator: Professor Mike Dragunow
for cell and organ-selective toxicity. Drugs, Email: m.dragunow@auckland.ac.nz
occupational and environmental toxicants are
discussed. MEDSCI 308 S1 H (15 points)
Molecular Neuroscience
Prerequisite: PHARMCOL 201 or MEDSCI 204 The molecular physiology of cellular homeostasis
and (PHYSIOL 210 or PHYSIOL 220 or BIOSCI and signalling. This discipline integrates
203 or MEDSCI 205 or MEDSCI 206) molecular biology, electrophysiology, imaging
Restriction: PHARMCOL 305 technologies and other advanced techniques in
Coordinator: Dr Malcolm Tingle molecular neuroscience and allied fields. The
Email: m.tingle@auckland.ac.nz course considers the characterisation and

2010 Biomedical Science Handbook | 35


manipulation of gene expression, and translation Prerequisite: 30 points from PHYSIOL 210,
to gene therapy treatments for neurological PHYSIOL 220, MEDSCI 205, MEDSCI 206
diseases. The lab component focuses on analysis
of gene expression and use of recombinant DNA Restriction: PHYSIOL 303
technologies. Practical training includes isolation Coordinator: Professor Janusz Lipski
of RNA, gene cloning, and DNA fingerprinting Email: physiology@auckland.ac.nz
using the polymerase chain reaction.
MEDSCI 311 S1 H (15 points)
Prerequisite: 30 points from PHYSIOL 210, Cardiovascular Biology
PHYSIOL 220, MEDSCI 205, MEDSCI 206 An advanced treatment of the human
Restriction: PHYSIOL 301 cardiovascular system that provides an integrated
Coordinator: Dr Srdjan Vlajkovic framework for understanding the structure,
Email: physiology@auckland.ac.nz function and regulation of the heart and
circulation, and their modification by drugs.
MEDSCI 309 S2 H (15 points) Topics include: the energetics and mechanics of
Biophysics of Nerve and Muscle the heart, the regulation of heart rhythm and the
An advanced treatment of the physiology of control of blood pressure and the regulation of
excitable cells. Topics include: the biophysical flow through the microcirculation. The course is
basis of membrane potential, the spread of illustrated using examples drawn from current
electrical activation and synaptic transmission, research in the field and from representative
structure, excitation, mechanics and energetics of disease states.
muscle and functional differences among muscle
types. The approach is quantitative with Prerequisite: PHYSIOL 210 or MEDSCI 205
particular emphasis on current advances in the Restriction: PHYSIOL 303
field. Coordinator: Professor Laura Bennet
Email: physiology@auckland.ac.nz
Prerequisite: 30 points from PHYSIOL 210,
PHYSIOL 220, MEDSCI 205, MEDSCI 206 MEDSCI 312 S2 H (15 points)
Restriction: PHYSIOL 302 Endocrinology of Growth and Metabolism
Coordinator: Associate Professor Christian An introduction to the mechanism controlling the
Soeller production of hormones and how these achieve
Email: physiology@auckland.ac.nz their effects in regulating body function. The
course focuses in particular on the hormone
MEDSCI 310 S2 H (15 points) systems controlling growth and metabolism and
Neurophysiology: Physiology and contrasts the differences between fetal and adult
Pathophysiology of the Brain life. It also highlights how defects in endocrine
The relationship between the structure and systems are associated with conditions such as
function of the nervous system in health and obesity and diabetes.
disease.  Topics include organisational principles
of CNS, imaging of the human brain, synaptic Prerequisites: 30 points from BIOSCI 203,
function in health and disease, selected topics in MEDSCI 205
pathophysiology of motor and sensory systems Restriction: PAEDS 301, PHYSIOL 305
(including vision and auditory function), brain Coordinator: Dr Kathy Mountjoy
ischemia and sleep/sleep disorders.  The topics Email: k.mountjoy@auckland.ac.nz
are covered at an advanced level with emphasis
in the fields.

36 | 2010 Biomedical Science Handbook


MEDSCI 313 S1 H Prerequisite: BIOSCI 202, 203
Reproductive Biology (15 points) Coordinator: Dr Clare Wall
Aspects of reproductive biology including: Email: c.wall@auckland.ac.nz
regulation of gonadal function, the menstrual
and oestrus cycles, ovulation spermatogenesis, PSYCH 305 S2 C (15 points)
feto-maternal physiology including placental Human Neuroscience
function, animal reproduction and assisted Covers material relating to the neural basis of
reproductive technologies cognitive processes, including perception,
attention, memory and language. Students will be
Prerequisite: BIOSCI 107 or HUMANBIO 142 or introduced to different methods of inferring
BIOSCI 203 or MEDSCI 142 mind-brain relations in normal and neurologically-
Restriction: OBSTGYN 351 impaired individuals, and different ways of
Coordinator: Associate Professor Andrew conceptualizing mind-brain relations, such as
Shelling connectionism and modularism.
Email: a.shelling@auckland.ac.nz
Prerequisite: 45 points in Stage II Psychology and
MEDSCI 314 S2 H (15 points) 15 points from STATS 101–125, 191, or 15 points
Immunology from either PHYSIOL 220 or MEDSCI 206
The biology, cellular and molecular events Coordinator: Dr Donna Addis
underlying the immune response. The nature and Email: d.addis@auckland.ac.nz
characteristics of antibody-mediated and
cell-mediated immunity including antigen Postgraduate Study in
recognition and presentation, antibody and T cell Biomedical Science
receptor structure, immune regulation and
Students may proceed to postgraduate study in in
cytokines, immunogenetics and histocompatibility.
Biomedical Science by selection for BSc(Hons) -
The relationships of the immune system to the
Biomedical Science or, through entry to PGDipSci
activities of pathogenic organisms. Applied
and MSc in Biomedical Science. The PGDipSci and
immunology including biotechnology, infection,
MSc in Medical Science have been discontinued in
autoimmunity, tumour immunology,
favor of the new Biomedical Science programmes.
transplantation and immunodeficiency.
Honours
Prerequisite: BIOSCI 201 or MOLMED 201 or
MEDSCI 202 • 90 points BIOMED 791A&B Research Portfolio
Restriction: BIOSCI 357
• 30 points from BIOSCI 736, 737, 741, 742,
Coordinator: Professor Phil Crosier
755-759, HLTHPSYC 716, MEDSCI 701-723,
Email: ps.crosier@auckland.ac.nz
725-734, 737
MEDSCI 315 S1 H (15 points)
A research portfolio will be prepared on the
Nutrition, Diet and Gene Interactions
dissertation topic.
Practical applications of nutrition in protection
against, and reduction of symptoms in, chronic Students will undertake a major piece of research
disease from a clinical perspective. Both work as part of this portfolio. Most research
non-communicable diseases (e.g. cancer, projects will be associated with the work of
osteoporosis, auto-immune disease) and research teams in the University.
communicable disease (e.g. whooping cough,
influenza) will be considered. Factors regulating Advice on the nature of the research portfolio and
appetite and food intake, and the role of how to choose a project will be given to students
genotype and epigenotype will also be studied. during semester 2.

2010 Biomedical Science Handbook | 37


PGDipSci 240 Points MSc
Prerequisite: A specialisation in Biomedical Prerequisite: A specialisation in Biomedical
Science, or equivalent as approved by the Board Science, or equivalent as approved by the Board
of Studies (Biomedical Science) of Studies (Biomedical Science)

Requirement: Requirement:
Research Masters:
• At least 90 points from MEDSCI 703-723,
725-737, BIOSCI 729, 733, 736, 737, 741, 742, • At least 90 points from MEDSCI 703-723,
755-761, HLTHPSYC 716 725-737, BIOSCI 729, 733, 736, 737, 738, 741,
742, 755-761, HLTHPSYC 716
• Up to 30 points from other 600 or 700 level
courses as approved by the Board of Studies • Up to 30 points from other 700 level courses
(Biomedical Science) as approved by the Board of Studies
(Biomedical Science)
MSc
120 Points MSc • 120 points: BIOMED 796 MSc Thesis in
Prerequisite: A BSc(Hons) in Biomedical, or a Biomedical Science
PGDipSci in Biomedical Science, or an equivalent Programme contacts
qualification as approved by the Board of Studies
(Biomedical Science) Margaret Goldstone
Faculty of Science
Requirement: Phone: 373 7599 ext 88622
Research Masters: Email: m.goldstone@auckland.ac.nz

• 120 points: BIOMED 796 MSc Thesis in Associate Professor Michelle Glass
Biomedical Science Faculty of Medical & Health Sciences
Phone: 373 7599 ext 86247
Email: m.glass@auckland.ac.nz

38 | 2010 Biomedical Science Handbook


Postgraduate courses
BIOSCI 729 (15 points) mutation on microbial and viral evolution and
Evolutionary Biology modern approaches used to link gene sequence
A contemporary approach to central issues in to biological function and phenotypes.
evolutionary biology including mechanisms that
produce macroevolutionary patterns. Current Coordinator: Dr Susan Turner
research using phylogenetic methods for testing Email: s.turner@auckland.ac.nz
evolutionary hypotheses will be discussed,
BIOSCI 737 (15 points)
encompassing the role of selection, the origin of
High Resolution Imaging of Biological
mutations, and concepts of heredity. A sound
Molecules
understanding of BIOSCI 322 or equivalent is
X-ray crystallography and electron microscopy
assumed.
are two of the principal techniques used by
Restriction: BIOSCI 706 biologists to determine molecular structure. The
Coordinator: Associate Professor Kendall theory and practice of X-ray crystallography and
Clements electron microscopy, including a laboratory
Email: k.clements@auckland.ac.nz component where 3D structures are determined
from experimental data, are addressed.
BIOSCI 733 (15 points) Accessible to students with a variety of
Molecular Ecology and Evolution backgrounds, including Biology, Bioengineering,
Interpreting the molecular archive by Chemistry and Physics. This course complements
reconstructing the branching history of CHEM 738 and BIOSCI 757.
inheritance and its relationship to genetic
diversity within and between species. Topics may Coordinator: Associate Professor Alok Mitra
include the neutral theory of molecular evolution, Email: a.mitra@auckland.ac.nz
rates of molecular evolution, molecular
BIOSCI 738 (15 points)
systematics, genome change and speciation,
Advanced Biological Data Analysis
molecular identification of species, gene flow and
Advanced biological data analysis, including
population structure, selection at the molecular
analysis of variance with nested and random
level, inbreeding depression and mutational load,
effects, analysis of covariance, cluster analysis,
and the use of molecular markers for estimation
principal components analysis, multidimensional
of kinship and the description of mating systems.
scaling, and randomisation methods. There will
A sound understanding of BIOSCI 322 or
be a practical component to this course involving
equivalent is assumed.
the use of appropriate statistical software.
Restriction: BIOSCI 719
Prerequisite: BIOSCI 209 or equivalent
Coordinator: Dr Shane Lavery
Coordinator: TBA
Email: s.lavery@auckland.ac.nz
Email: TBA
BIOSCI 736 (15 points)
BIOSCI 741 (15 points)
Advanced Microbial Genetics
Applied Microbiology and Biotechnology
Cross-disciplinary issues involved in the
Historical overview of the development of
understanding of microbial genome structure,
industrial microbiology. Diversity and complexity
gene regulation and metabolism. Includes: the
of applications. Biodiversity of fermentations.
genetic basis of microbial interactions and
Microbial metabolism and the assimilation of
horizontal gene transfer, the effect of stress and
carbon, nitrogen and sulphur. Interconnections

2010 Biomedical Science Handbook | 39


between catabolic and biosynthetic pathways. approaches used to link protein sequence and
Metabolic considerations in continuous culture. function. The application of proteomics to drug
Selection, isolation and construction of useful action, discovery and toxicology will be included.
organisms. Manipulation of growth conditions to A sound understanding of BIOSCI 350 or
optimise process yield. Contemporary examples equivalent is assumed.
of industrial processes using microbes. A sound
understanding of BIOSCI 352 or equivalent is Coordinator: Associate Professor Tom Brittain
assumed. Email: t.brittain@auckland.ac.nz

Coordinator: Dr Matt Goddard BIOSCI 757 (15 points)


Email: m.goddard@auckland.ac.nz Structural Biology
A selection of contemporary topics in the field of
BIOSCI 742 (15 points) structure and function of important biomolecules
Bioinformatics and Computational Biology and cellular activities. Topics may include: protein
A selection of contemporary topics in the field of folding in the cell; motor proteins; influenza and
plant biochemistry, including molecular aspects HIV; protein structure determination; protein
as pertaining to bioinformatics. Topics may structure and function from genomic data. A
include: biosynthesis of cell-wall components, sound understanding of BIOSCI 350 or equivalent
including cellulose and lignin; metabolism of is assumed.
nitrogen as an essential macronutrient; free
radicals in plant biology. A sound understanding Restriction: BIOSCI 717
of BIOSCI 340 or equivalent is assumed. Coordinator: Associate Professor Peter Metcalf
Email: peter.metcalf@auckland.ac.nz
Restriction: BIOSCI 359
Coordinator: Professor Philip Harris BIOSCI 758 (15 points)
Email: p.harris@auckland.ac.nz Development, Differentiation and Disease
A critical analysis of normal and perturbed gene
BIOSCI 755 (15 points) expression in selected model organisms and
Genomics and Gene Expression humans as a means of understanding biological
This course will address the analysis of genomes pathways important in development and disease.
and gene expression as a means of A sound understanding of BIOSCI 356 or
understanding biological processes. Aspects of equivalent is assumed.
functional and chemical genomics will be
presented, as well as gene expression profiling Restriction: BIOSCI 714, BIOSCI 740
using microarray technology. Features of Coordinator: Dr Lorna Johnstone
experimental design and data analysis will be Email: ls.johnstone@auckland.ac.nz
discussed in the context of disease and
BIOSCI 759 (15 points)
developmental processes. A sound understanding
Molecular Cell Biology and Biomedicine
of BIOSCI 351 or equivalent is assumed.
Explores recent advances in cell biology that have
Restriction: BIOSCI 714 led to a greater understanding of a variety of
Coordinator: Associate Professor Brian Murray cellular processes at the molecular level.
Email: b.murray@auckland.ac.nz Emphasis will be placed on biochemical and
genetic approaches to understand disease
BIOSCI 756 (15 points) mechanisms at the cellular level. A sound
Proteomics and Protein Interactions understanding of either BIOSCI 349 or 353 or
Proteomics describes a field of research MEDSCI 314 or equivalent is assumed.
concerned with the large-scale study of protein
expression and function. Highlights biochemical Coordinator: Dr John Taylor
Email: ja.taylor@auckland.ac.nz

40 | 2010 Biomedical Science Handbook


Restriction: ANATOMY 751
Coordinator: Professor Alistair Young
Email: a.young@auckland.ac.nz

MEDSCI 704 (15 points)


Developmental Genetics
Genetics approaches used to understand
developmental mechanisms. These utilise a
variety of model systems including Drosophila
and Zebrafish to study processes such as pattern
formation, cell specification, lineage commitment
and cell-cell interaction. Insights into control of
MEDSCI 701 (15 points)
these events are critical to advancing
Special Studies in Medical Science 1
understanding of disease processes, particularly
A specific course of study for one or more
cancer.
students. Available only by arrangement between
the staff member(s) and students. Restriction: MOLMED 701
Coordinator: Professor Phil Crosier
Restriction: MEDSCI 702
Email: ps.crosier@auckland.ac.nz
Coordinator: Associate Professor Roger Booth
Email: rj.booth@auckland.ac.nz MEDSCI 705 (15 points)
Infection, Immunity and Disease
MEDSCI 702 (15 points)
Examines the ways in which host immune
Special Studies in Medical Science 2
mechanisms control infection, infectious
The critical review and analysis of research
organisms evade host defence mechanisms, and
literature relating to a research topic. 
the consequences of these processes for the host.
Components include an extensive literature review
Examples of human infectious diseases will
article defining the current knowledge relevant to
include: HIV, hepatitis B, influenza, tuberculosis
a particular research area, a research proposal
and streptococcal infections. Consideration of
outlining proposed master’s research topic and its
the consequences of infection will incorporate
significance, and a formal presentation of the
discussion of immune self/non-self discrimination,
proposal.  Suitable for students intending to
immune tolerance and autoimmune mechanisms,
undertake a Master’s thesis.
including the impact of response against
Restriction: MEDSCI 701 infections on autoimmunity.
Coordinator: Associate Professor Roger Booth
Restriction: MOLMED 708
Email: rj.booth@auckland.ac.nz
Coordinator: Associate Professor Roger Booth
MEDSCI 703 (15 points) Email: rj.booth@auckland.ac.nz
Advanced Biomedical Imaging
MEDSCI 706 (15 points)
Theory and practice of biochemical imaging from
Genetic Disease
the sub-cellular to whole body level with specific
Examines a range of medical genetic disorders
emphasis on recent developments. Principles of
that illustrate principles of disease mechanisms,
digital image-processing and image analysis
diagnosis and management. These will include:
(including quantitative morphology), computed
haemophilia, familial cancer, late-onset
tomography and volume rendering and analysis.
neurological disorders and mitochondrial disease.
Imaging modalities including atomic force
microscopy, light and confocal microscopy, Restriction: MOLMED 710
electron microscopy, x-ray, CT, ultrasound and Coordinator: Professor Peter Browett
magnetic resonance imaging. Email: p.browett@auckland.ac.nz
2010 Biomedical Science Handbook | 41
MEDSCI 707 (15 points) MEDSCI 710 (15 points)
Activities of Microbes in Disease Nutrition Mechanisms
The dynamic interaction between pathogenic The mechanisms by which food and food
micro-organisms and humans will be explored. components can influence disease processes
Examines the molecular mechanisms which including: the interaction between genotype and
enable microbes to survive, proliferate and cause nutrition, antioxidants and oxidation protection
disease; to evolve and acquire new genes; and to mechanisms, dietary toxicology, the process of
control the expression of their genes. Emphasis atherosclerosis, and the influence of the
will be placed on recent advances in the intra-uterine environment on growth and disease.
understanding of major human microbial
diseases. Restriction: NUTRN 701
Coordinator: Professor Lynnette Ferguson
Restriction: MOLMED 711 Email: l.ferguson@auckland.ac.nz
Coordinator: Dr Simon Swift
Email: s.swift@auckland.ac.nz MEDSCI 711 (15 points)
Clinical Nutrition
MEDSCI 708 (15 points) Prevention of malnutrition and maintenance of
Advanced Immunology and Immunotherapy nutritional status during acute and chronic illness
Recent advances in immunology including: the through ‘artificial’ or ‘interventional’ means.
genes and proteins involved in the innate and Diagnosis and quantitation of malnutrition, and
adaptive immune response, intracellular monitoring of nutrition support therapy. Practical
signalling mechanisms that determine immune techniques, common complications and quality
outcomes, and the mechanisms by which the assurance through a multidisciplinary team
immune system learns ‘self’ from ‘non-self’. approach. Includes treatment of anorexia nervosa
Examines a range of inflammatory diseases, and and cancer cachexia.
methods of immunotherapy, in particular
approaches to combat cancer. Restriction: NUTRN 702
Contact: Associate Professor Lindsay Plank
Restriction: MOLMED 712 Email: l.plank@auckland.ac.nz
Coordinator: Associate Professor Geoff
Krissansen MEDSCI 712 (15 points)
Email: gw.krissansen@auckland.ac.nz Critical Evaluation of Nutritional Therapies
The suggested roles for micronutrients,
MEDSCI 709 (15 points) ‘nutriceuticals’ and functional foods in general
Nutrition in Health and Disease health, exercise performance and disease are
The influence that dietary patterns, foods and evaluated using an evidence-based approach. The
food components have on the promotion and roles of micronutrients as dietary supplements
protection against the common nutrition-related and the potential actions of nutriceuticals and
diseases in New Zealand. The relevant functional foods are also critically evaluated.
epidemiological, clinical, and biochemical/ Regulatory and ethical issues in the use of
physiological aspects of each disease are nutritional remedies are considered, including
covered. their use as supplements in chemotherapy or
other conventional therapies, or in individuals
Restriction: NUTRN 700 with no symptoms.
Contact: Professor Lynnette Ferguson
Email: l.ferguson@auckland.ac.nz Restriction: NUTRN 703
Contact: Dr Clare Wall
Email: c.wall@auckland.ac.nz

42 | 2010 Biomedical Science Handbook


MEDSCI 713 (15 points) genomic instability, telomeres and telomerase,
Principles of Cancer Therapy anoikis, DNA damage sensing mechanisms, and
Examines the molecular and cellular processes hypoxia and tumour progression.
underlying cancer treatment and the
development of tumour-selective therapy; the Prerequisite: MEDSCI 302
principles of radiotherapy and chemotherapy; Restriction: PATHOL 705
DNA and the basis for its interactions with Coordinator: Dr Maggie Kalev
anticancer drugs; recognition of DNA by proteins; Email: m.kalev@auckland.ac.nz
exploitation of these processes by anticancer
MEDSCI 715 (15 points)
drugs, oncogenes and other regulatory gene
Molecular Toxicology
products; signal transduction mechanisms and
Covers the current understanding of mechanisms
strategies for changing cell cycle control;
implicated in toxicity of drugs and environmental
cytokines and the role of host responses in cancer
chemicals plus the basis of inter-individual
therapy; new approaches to cancer therapy
susceptibility. The course identifies strategies
including gene therapy and photodynamic
used to predict and prevent adverse reactions
therapy.
during drug development.
Prerequisite: MEDSCI 302
Restriction: PHARMCOL 711
Restriction: PATHOL 704
Contact: Dr Malcolm Tingle
Coordinator: Dr Maggie Kalev
Email: m.tingle@auckland.ac.nz
Email: m.kalev@auckland.ac.nz
MEDSCI 716 (15 points)
MEDSCI 714 (15 points)
Drug Disposition and Kinetics
Advanced Cancer Biology
Advanced study of the absorption, distribution,
Advanced studies of concepts related to the
metabolism and excretion of drugs, and the
biology of cancer. These will include: molecular
analysis of these processes. Also included are:
mechanisms, signal transduction pathways,

2010 Biomedical Science Handbook | 43


invivo/invitro techniques in drug ADME studies MEDSCI 720 (15 points)
used in drug development; drug analysis in Biomedical Research Techniques
biological matrices; and pharmaco-genomic An introduction to some of the most commonly
aspects related to drug disposition. used techniques used in today’s research
laboratories; from tissue culture to confocal
Restriction: PHARMCOL 712 microscopy, RT-PCR to mass spectrometry,
Contact: Associate Professor James Paxton immunoassay to cloning. Emphasis is placed on
Email: j.paxton@auckland.ac.nz understanding the principles behind the
techniques, how they are applied to address
MEDSCI 717 (15 points)
specific questions, and how to evaluate and use
Advanced Neuroscience:
the data they generate.
Neuropharmacology
An advanced study of current research topics in Restriction: PHARMCOL 719
neuroscience. Involves critical analysis of the Course Coordinator: Dr Debbie Young
literature within the context of a series of major Email: ds.young@auckland.ac.nz
research themes that encompass models from
molecular through to systems level neuroscience. MEDSCI 721 (15 points)
Themes will be selected from the following areas: Advanced Toxicology
neurogenesis, neurodegeneration and/or Focuses on classes of drugs associated with
addiction. idiosyncratic adverse reactions and studies to
define their metabolic basis and assessment of
Restriction: PHARMCOL 713 toxic risk.
Contact: Associate Professor Bronwen Connor
Email: b.connor@auckland.ac.nz Restriction: PHARMCOL 721
Contact: Dr Malcolm Tingle
MEDSCI 718 (15 points) Email: m.tingle@auckland.ac.nz
Pharmacology of Anaesthetics and
Analgesics MEDSCI 722 (15 points)
General aspects of anaesthetics and analgesics Clinical Pharmacology
including the development of modern anaesthesia, The disposition and action of drugs in the elderly,
the mechanisms of action of drugs used in general young and in pregnancy will be considered, as
and local anaesthesia, and issues surrounding well as therapeutic drug monitoring,
safety and efficacy of anaesthesia, including drug pharmacoeconomics, adverse drug reactions,
error and circadian variation in drug action. ethnic differences in PK’s and PD’s, evaluation of
clinical trials and population kinetics. Emphasis is
Restriction: PHARMCOL 715 placed on the use of medicines in humans.
Contact: Dr Guy Warman
Email: g.warman@auckland.ac.nz Restriction: PHARMCOL 722
Contact: Professor Nick Holford
MEDSCI 719 (15 points) Email: n.holford@auckland.ac.nz
Pharmacometrics
An introduction to the application of mathematical MEDSCI 723 (15 points)
models used in the interpretation of Cancer Pharmacology
pharmacological observations. Computer-based The pharmacological basis of the action of
analysis methods are investigated using individual anti-tumour drugs relevant to human cancer
and population-oriented approaches. therapy, emphasising the variability of
chemotherapy effects, interactions between
Restriction: PHARMCOL 716 anti-cancer agents and early phase clinical trials.
Contact: Professor Nick Holford
Email: n.holford@auckland.ac.nz

44 | 2010 Biomedical Science Handbook


Restriction: PHARMCOL 728 Prerequisite: MEDSCI 312 or PHYSIOL 305
Contact: Associate Professor Mark McKeage Restriction: PAEDS 701, 702, 703, PHYSIOL 708
Email: m.mckeage@auckland.ac.nz Coordinator: Dr Mhoyra Fraser
Email: physiology@auckland.ac.nz
MEDSCI 725 (15 points)
Experimental Design MEDSCI 730 (15 points)
Principles of experimental design and data Reproductive Science
analysis in physiological research. Topics include: Molecular regulation and coordination of normal
analysis of variance, post-hoc multiple reproduction.  The reproductive disorders that
comparisons, non-linear and multiple linear arise when normal biological processes are
regression, analysis of covariance and statistical disrupted.  Recent molecular methods have
power. The approach is practical and computer enabled us to study these processes and to
statistical packages are used. understand how they can go wrong.  Genomic
and proteomic approaches to the understanding
Restriction: PHYSIOL 701 of reproduction and reproductive disorders will be
Coordinator: Dr Denis Loiselle presented.  Examination of the new technologies
Email: physiology@auckland.ac.nz that allow us to overcome some of these
reproductive problems.
MEDSCI 727 (15 points)
Advanced Neuroscience: Neurophysiology Prerequisite: 15 points from BIOSCI 351, 353,
An advanced treatment of selected topics in 356, MEDSCI 312, 313, OBSTGYN 351, PHYSIOL
neurophysiology. Involves presentations and 305
critical analysis by the students of the current Restriction: OBSTGYN 706
scientific literature within the context of several Coordinator: Associate Professor Andrew
major research themes that encompass models Shelling
from molecular and cellular to systems levels. Email: a.shelling@auckland.ac.nz
Themes will be selected from the following areas:
(1) motor control and motor disorders (Parkinson’s MEDSCI 731 (15 points)
disease, motorneuron disease, stroke); (2) synapse Reproductive Medicine
physiology and pathophysiology; (3) advances in Understanding normal reproductive events and
neural stem cell research; and (4) selected topics how normal biological processes are disrupted to
in sensory neuroscience research. cause medical problems. A range of specific
disorders of reproduction (Pre-eclampsia,
Restriction: PHYSIOL 703 polycystic ovarian syndrome, endometriosis),
Coordinator: Professor Janusz Lipski including infertility and gynaecological cancer,
Email: physiology@auckland.ac.nz will be discussed. Attention will be given to the
recent advances in understanding of disease at a
MEDSCI 729 (15 points)
molecular level and how they translate to become
Perinatal Physiology and Medicine
a clinical disorder.
Fetal development has long-term consequences
for health. This advanced course offers a wide Prerequisite: 15 points from OBSTGYN 351,
range of research themes relating to fetal PHYSIOL 305, BIOSCI 351, 353, 356
development and future health. Topics include: Restriction: OBSTGYN 707
placental development, fetal physiology and Coordinator: Associate Professor Larry Chamley
endocrine regulation and metabolic function Email: l.chamley@auckland.ac.nz
during fetal and postnatal life. The course
explores pathogenesis of disease and injury of the
fetus and newborn, and how biomedical research
leads to potential clinical treatment strategies.

2010 Biomedical Science Handbook | 45


MEDSCI 732 (15 points) MEDSCI 737 (15 points)
Molecular Aspects of Endocrinology and Biomedical MRI
Metabolism Designed to give students a thorough
Explores how hormones are able to control such a understanding of a range of biomedical MRI
wide range of physiological processes. Covers techniques as well as advanced clinical MRI
molecular aspects of hormone action with applications such as functional imaging of the
particular reference to the neuroendocrine and brain and cardiovascular system. Laboratories will
peripheral endocrine systems that control cover MRI pulse programming, MRI applications in
appetite and metabolism. Other topics covered basic science, and MRI applications in clinical
include how defects in hormone action lead to medicine.
diseases such as cancer, obesity, Type-2 diabetes
and cardiovascular disease. Coordinator: Dr Alistair Young
Email: a.young@auckland.ac.nz
Coordinator: Professor Peter Shepherd
Email: peter.shepherd@auckland.ac.nz HLTHPSYC 716 (15 points)
Psychoneuroimmunology
MEDSCI 733 (15 points) Outlines the nature of the human immune system,
Advanced Methods in Cell Physiology its measurement and limitations of current
The theoretical basis underpinning practices and models. The main focus of the
electrophysiological and live cell imaging course is the extent to which psychological
techniques. Emphasis will be placed on the processes such as stress, emotions and social
instrumentation, data acquisition, and data interactions have been found to influence immune
analysis associated with such technology. The behaviour and the implications of these findings
approach is practical and computer-based for health and wellbeing. Various theoretical
software programmes are used to analyse frameworks through which psycho-immune
pre-recorded data, and data produced by the relationships might be understood are presented
students themselves. and discussed.

Restriction: MEDSCI 726, PHYSIOL 702 Coordinator: Associate Professor Roger Booth
Coordinator: Dr Kim Dirks Email: rj.booth@auckland.ac.nz
Email: k.dirks@auckland.ac.nz
BIOMED 791A&B Research Portfolio in
MEDSCI 734 (15 points) Biomedical Science 45 Point(s), Thesis
Advanced Integrative Physiology An integrated combination of research in an
In the post-genomic world the limitations of advanced biomedical science research option,
reductionism as a basis for understanding consisting of supervised practical work and
complex function have become apparent and it is independent critical analysis of research in the
necessary to integrate genomics with the biology field.
of organ systems. This course will portray how an
integrative physiological approach can reveal Restriction: BIOMED 790
new levels of understanding in the field of To complete this course students must enrol in
biomedical research. Examples of this approach BIOMED 791 A and B.
will be drawn from research programmes within
BIOMED 796A&B
the areas of cardiovascular biology, fetal
MSc Thesis in Biomedical Science (120 points)
physiology, neurophysiology and vision.
Restriction: MEDSCI 796
Restriction: MEDSCI 728, PHYSIOL 705
To complete this course students must enrol in
Coordinator: Associate Professor Simon Malpas
BIOMED 796 A and B.
Email: physiology@auckland.ac.nz

46 | 2010 Biomedical Science Handbook


Advice and support
for students
Academic honesty 48
The University of Auckland Library 51
Student services 52
Improve your English langauge skills 56
Students support services 57
Campus maps 58

2010 Biomedical Science Handbook | 47


Academic honesty
What does The University of Examples of plagiarism
Auckland expect of students?
• Copying or quoting directly a sentence,
All students and staff members of The University
sentences, paragraphs from any printed or
of Auckland’s academic community, which shares
electronic work created by another without
values such as trust, mutual respect, honesty,
proper acknowledgment or referencing.
integrity and fairness.
• Paraphrasing the original source without
1. Work students submit for grading – in
proper acknowledgment or referencing.
coursework and examinations – must
ultimately be their own work, reflecting each • Copying images, sounds, tables, graphics,
student’s learning and performance. research, results, computer programmes,
statistical data, ideas, concepts or text without
2. Where work (ideas, statements, data,
proper acknowledgment or referencing.
illustrations or examples) from other sources is
used in coursework, it must be properly • Cut and paste from a source or sources and
acknowledged and referenced. presenting it as original work.

3. Cheating is a serious academic offence. Marks • Copy unauthorised notes or another student
and qualifications acquired through cheating during exams.
are acquired dishonestly and do not truly
represent the student’s abilities. The grades • Using information and material from a website
and qualification that students earn without attribution.
legitimately through their own efforts are
de-valued if other students cheat. Submitting someone else’s work or ideas without
acknowledgement or attribution is not evidence
4. The University of Auckland will not tolerate of your own grasp of the material and cannot
cheating, or assisting others to cheat. earn you marks.

Students should also consult the University’s page


What are the types of academic concerning plagiarism called Referencite,
dishonesty or cheating? www.cite.auckland.ac.nz, for information on how
Academic dishonesty can take many forms, to avoid plagiarism, which information needs to
including: be referenced and advice on quoting,
summarising and paraphrasing.
Plagiarism
1. Copying from another student.
• Plagiarism means using the work of others in
preparing an assignment and presenting it as • This includes copying done with or without the
your own without explicitly acknowledging - or knowledge of another student. It also includes
referencing – where it came from. Plagiarism someone’s coursework that had been
can also mean not acknowledging the full submitted in a previous year – at any
extent of indebtedness to a source. Work can educational institution. Examples would
be plagiarised from many sources – including include:
books, articles, the internet and other students’
assignments. Plagiarism can also occur • Copying all or part if someone else’s
unconsciously or inadvertently. coursework, assignment or examination.

48 | 2010 Biomedical Science Handbook


• Allowing someone else to do all or part of an
assignment for you.

• Doing all or part of someone else’s assignment


for them.

2. Making up or fabricating data.

• This includes using false data in the writing up


of laboratory reports, or using made-up
quotations from interviewees.

3. Submitting the same, or a substantially


similar, assignment that you have done
for assessment in more than one course.

4. Using material obtained from commercial


essay or assignment services, including
web-based sources.

• Buying or otherwise acquiring essays, answers


or ideas (in whole or in part) and using them in
a coursework assignment is unacceptable.

5. Impersonating someone else.

• This includes representing another student at a 9. Using work done as part of ‘group study’
test or examination, or arranging for someone or a ‘team’ project in unauthorised ways.
to represent a student.
• This includes a group of students working
6. Misrepresenting disability, temporary though to the solution of what is intended to
illness or injury or exceptional be an individual’s assignment.
circumstances beyond your control, and
then claiming special conditions. • Students should consult the document
‘Guidelines: Conduct of Coursework’ for
7. Asking or letting a ‘third party’ help in further guidance.
preparing your assignment in ways not
authorised by the University. Academic Misconduct: What happens if I
am not honest about my academic work?
• Students should consult the document ‘Use of
If a student deliberately cheats and receives a
Third Party Assistance in Undergraduate and
penalty, the case will be recorded in a University-
Postgraduate Coursework: Guidelines for
wide Register. The record of the offence will
Students’ for guidance as to what is
normally remain until one year after the student
permissible concerning receiving help from a
graduates. The Register will help identify repeat
‘third party’ (i.e. someone other than your
offenders, with the risk that these students will
teachers).
receive more severe penalties for repeat offences.

2010 Biomedical Science Handbook | 49


How is group work graded
On the whole, the University requires assessment
of the work of individual students. On those rare
occasions where the work of a group of students
is assessed, group members need to make sure
that the workload is shared equally. Course
coordinators will determine their own procedures
for dealing with cases where the final piece of
work reflects unequal participation and effort.

Where you can get help


Typically students cheat because they are having
difficulty managing workloads, feel that the
course content is too difficult or experience
difficulties with the language of the course. None
of these reasons are justification for cheating. The
University provides many services to help
students receive assistance, do better or to make
thoughtful decisions about whether to continue.
Options of people to approach for assistance Applications for Aegrotat and
include: Compassionate Consideration
An application may be made for aegrotat or
• The course convenor/coordinator, lecturer, compassionate consideration, by candidates who
tutorial leader, lab demonstrator may have been prevented from being present at
• Head of Department an examination, or who consider that their
preparation for or performance in an examination
• Faculty-level official
has been seriously impaired by temporary illness
• Health and Counselling services or injury or exceptional circumstances beyond
• Student Learning Centre their control. This also applies to tests, but not
assignments.
• AUSA or other students’ associations
• Chaplaincy services Application forms are available online, or from
the relevant campus University Health Services
The guidelines on Conduct of Coursework and
and Examinations Office.
cheating are set out in full on the Teaching and
Learning website at www.auckland.ac.nz/uoa/ The application form must be submitted to the
about/teachingandlearning/ University Health Services within one week of the
Academichonestyandplagiarism date the examination affected took place, or if
more than one examination has been affected,
then within one week of the last of those
examinations.

Following the decision of Senate on an


application of Aegrotat or Compassionate
Consideration, a student will be informed in
writing of the final decision. If the application is
declined, students have four weeks in which to
apply for reconsideration of the decision.

50 | 2010 Biomedical Science Handbook


University Library
Te Tumu Herenga
The University Library consists of the General Library and 12 subject-specific libraries with
over 2.2 million volumes, a world-class digital library collection, 4700 study spaces with
1100 of those providing access to a computer.

General Library Services


Most science serials are now available Visit the subject librarians in Science Information
electronically. The majority of the science book Services on level M. Consultation sessions are
collection is shelved on Level M where you will available during visits made by the Subject
also find printed serial collections for biology, Librarian to the Departments.
marine science, chemistry, computer science,
food science, geology, physics, mathematics and Other Library services include Ask a Librarian
statistics. Geography, computer science and Service, Enquiry Desk, Information Commons
psychology serials are shelved with the book Help Desk, Inter-Campus Library Delivery Service,
collection. Interlibrary Loan and Document Delivery and the
Short Loan Collection.
Tamaki Library has resources in computer
science, physics, psychology and sport and Subject Librarians
exercise science. Visit the subject librarians in Science Information
Services on Level M. Consultation sessions are
Leigh Marine Research Laboratory Library has available during visits made by the Subject
marine science resources. Librarian to the Departments.

Courses, tours and training Borrowing and accessing resources


Tours and hands-on courses will give you the Your student ID card is your Library card. Use it
confidence to use the University Library, its to access the photocopiers, printers and to
Information Commons service and all its borrow items. You also have 24-hour access via
resources. If you are a new student, the following the Library website
courses are recommended:
General Library
Library and Resources Overview: an introduction
5 Alfred Street, City Campus
to the University Library resources and services.
Phone: 373 7599 ext 88044
Database Searching: how to choose and use www.library.auckland.ac.nz
databases.

Uni IT Essentials: covers University IT facilities,


Netaccount and NetID, Cecil, Webmail, wireless
and other electronic resources.

To book a Library course visit


www.library.auckland.ac.nz/booking

2010 Biomedical Science Handbook | 51


Student services
Information Commons Student Learning Centre
Designed as information hubs, the The Student Learning Centre facilitates the
Information Commons give you computer development of effective academic learning and
access and learning support, as well as research skills for all students, from first year to
proving group and individual study areas. postgraduate. Advice is offered via workshops
You’ll find these facilities at our City, and individual consultations as appropriate.
Grafton and Epsom campuses.
Specific programmes cater for:
Use one of the Information Commons computers
• Undergraduate Skills eg: Time management,
or laptops to access your coursework through
writing, reading, exams
Cecil (the University’s e-learning system), send
emails and browse the Internet, and to complete • Postgraduate Skills eg: Project/thesis writing,
coursework using MS Office, Adobe Master research methods, seminars
Collection and other software. You can retrieve
information from the library databases, e-journals, • Te Puni Wānanga – Support for Māori students
e-books and electronic course materials - including
recommended readings. You also have access to • Fale Pasifika – Support for Pasifika students
printers, scanners and photocopiers. Wireless
• English as an Additional Language (EAL) eg:
networking technology is available.
Critical thinking, reading, writing
At the Kate Edger Information Commons on the
• Mathematics and Statistics – Support for
City Campus you will find computer training
specific credit courses
rooms, the Student Learning Centre, a Disabilities
Resource room, the Library’s Short Loan service • Computer Skills eg: MS Word (Formatting)/
and the English Language Self-Access Centre Excel/PowerPoint; SPSS; EndNote
(ELSAC).
• Students experiencing learning/other
The IC Helpdesks provide walk-in, roaming, email disabilities eg: Handwriting, spelling, writing
and telephone support with all aspects of student
computing resources and services. If you want to It is necessary to register with the SLC to utilise
develop your IT and information literacy you can our services, this costs $10 for the calendar year.
attend a training course, use electronic resources
on the Library and Information Commons web Student Learning Centre
sites or ask a staff member for help. Centre for Academic Development
Level 3, Information Commons
Information Commons 9 Symonds Street, Auckland
Phone: 373 7599 ext 82333
Email: ichelpdesk@auckland.ac.nz Phone: +64 9 373 7599 ext. 88850
www.information-commons.auckland.ac.nz Email: slc@auckland.ac.nz
www.slc.auckland.ac.nz

52 | 2010 Biomedical Science Handbook


Careers
A science degree from The University of Auckland
will give you a foundation of knowledge and skills
that can lead to a wide range of career
opportunities. Graduates may begin their careers
in research organisations, local government,
central government, universities, commerce and
industry, international and community
organisations.

University Careers Services can assist you with


your career decision making and job search
throughout the course of your studies. It is never
too early to start planning to get the career you
want.

Visit us to discuss your career opportunities, have


your CV and cover letter checked, practice for
interviews, attend job hunting workshops, access
our wide range of information and resources and
find out about internships, vacancies and
potential employers. Our service is free and
available to all current students and recent
graduates of The University of Auckland. University Careers Services
Science Student Centre drop-in: 12-2 Tuesday
A specialist Postgraduate Careers Consultant is Sci-Space drop-in:12-2 Thursday
also available (postgraduate@auckland.ac.nz) to Contact Sean Pulman
work with PhD and Research Masters students. Email: s.pulman@auckland.ac.nz
It is recommended that students attend employer City Campus
event presentations and fairs, generally held in Room 001, ClockTower, 22 Princes Street
the first semester. Attendance at these will help Open Monday – Friday all year
you gain more information about the wide range 8.30am to 5pm
of career options available with your science Phone: 09 373 7599 ext 88727
degree. You should note that recruitment by key Email: careers@auckland.ac.nz
government departments and management
consultancies occurs early in the year. Tamaki
Appointments can be made at the Student
Careers Services advertises job search workshops, Resource Centre
job vacancies, internships, employer presentations Phone: 09 373 7599 ext 85230
and careers fairs on Auckland CareerHub at Email: tamakicareers@auckland.ac.nz
www.auckland.ac.nz/careerhub www.auckland.ac.nz/careers
For further information please visit our website at
www.auckland.ac.nz/careers

2010 Biomedical Science Handbook | 53


Welcome to the new WAVE WAVE is located in
AUSA House, 4 Alfred Street
in representation services (across from the General Library)
for students!
Contact us on
WELFARE is a welfare referral service. If you’re Phone: 373 0789 x251
stressed, hungry or have exhausted your Email: wave@auckland.ac.nz
overdraft - we try to help! We have an onsite food
bank and hardship funds that you can apply for. Check out our web page at
We can also put you in contact with the right www.ausa.auckland.ac.nz/wave
people and agencies to provide you with the
resources you need.
Chiasma
ADVOCACY is run by the Advocacy Manager The Link in Biotech Enterprise aims to promote a
with support from the Advocacy Assistant and generation of business-savvy scientists with an
the Student Advocacy Network (SAN). If you feel enterprising spirit amongst the bioscience
you have been treated unfairly or have a community at The University of Auckland and to
grievance with the University, WAVE provides a foster the development of networks between the
confidential, free service available to all students. university and the wider New Zealand biotech
They can advise on student rights and university industry sector. Students across the bioscience/
procedures, assist in resolving disputes involving biotech-related faculties (Faculty of Medical and
students or staff, and provide information and Health Sciences, School of Biological Sciences,
referrals. They can also provide general legal Bioengineering Institute and Business School) are
advice on issues such as tenancy, employment encouraged to benefit from this initiative.
and many other areas of law. SAN hours are
10am - 12 noon every weekday during semester. Chiasma’s activities are split into three key
You can also contact the Advocacy Manager and programmes; I-Volve, Career Catalyst & Synapse.
Advocacy Assistant on Phone 309 0789 ext 202 I-Volve challenges participants to propose a novel
or 251. biotech-related product/service with the potential
to become a successful ‘real world’ venture.
VOICE is student representation - Class Reps and Career Catalyst is a series of workshops and
students on University committees. WAVE offers seminars for bioscience students to enhance their
class rep training, class party funding, a class rep professional development and to gain knowledge
handbook and quarterly newsletters. They also of commercial issues. Synapse is Chiasma’s
organize the election, training and support of annual premiere Biotech Industry & Career Expo
University Committee Reps. University featuring top-level executives from prominent
committees set the direction for The University of New Zealand biotech companies.
Auckland, drafting policy and regulations. You
can have your say through student committee Along with these key events Chiasma is
reps. Check out their website at www.ausa.org. continually developing other events and initiatives
nz/wave for more details! to benefit its student, staff and industry members.
These include industry site visits, valuable
The EDUCATION Vice President (EVP) acts on internship and career opportunities, and
wider educational issues that affect you. This may opportunities to form new and innovative
include submissions to the University and to research collaborations.
central Government. Their role involves bringing
concerns about education matters to the wider For more information, check out our webpage at
community. www.chiasma.auckland.ac.nz or email
chiasmateam@gmail.com.
54 | 2010 Biomedical Science Handbook
Science IT Support The Student Resource Centre distributes and sells
www.sit.auckland.ac.nz/science_IT_support course books.

Located behind the Student Resource Centre, you


Computer access will find the Tutorial Assistance Area, a teaching
The Faculty of Science has several computer labs and learning environment for mathematics and
for students to use. Students should be aware statistics students where tutors, identified by their
that each school or department has protocols in coloured sashes, are available to assist with any
place to ensure that equipment is not used for difficulties you may have with assignments or
purposes other than those allowed, and that a understanding lectures. Tutors are usually
pleasant and productive working environment is available between 10.00am and 4.00pm on
possible for everyone. Computer Systems weekdays during term time. The space, furnished
Regulations are broadly outlined in The University with round tables, is peer based, promotes
of Auckland Calendar. student-initiated learning and fosters information
sharing.
www.slc.ec.auckland.ac.nz
On the other side of the Student Resource Centre
Science Computer Labs: is a large, comfortable area equipped with tables,
Stage 1 CS students: OCL, R303-130 chairs and a microwave, providing a friendly
Stage 2 and 3 CS students: FCL, R303-191 environment in which to relax between lectures.
Software Engineering students: GCL R303-G91
Math and Stats students: BCL, R303-B91 You will find Sci-Space in Room G16, Ground Floor
Science Centre, Building 303.

International Students
iSPACE is an area for international students to
meet other students, obtain information and
attend organised activities and workshops.
iSPACE is located on Level 4 of the Kate Edger
building on the City Campus. You will have
access to international magazines so that you
can find out what is happening in your country.
You can attend regular workshops and
information sessions to help you adjust to living in
New Zealand. There will be social and cultural
activities to help you make friends.

Pastoral care for international students


If you need top talk to someone about problems
or difficulties you may be having, you can speak
Introducing Sci-Space to one of the International Student Advisors. They
offer a free and confidential service to help you
Sci-Space is a friendly, casual drop in centre for
seek assistance with any issues related to your
students where you will find the Student Resource
studies, accommodation, health, money,
Centre, Mathematics and Statistics tutorial
adjusting to life in New Zealand, work or
assistance and a spacious, informal area where
immigration. You will also have access to all other
you can study or catch up with friends to chat or
support services at the University.
have a snack.

2010 Biomedical Science Handbook | 55


Improve your English
language skills
All first-year students are required to undertake an assessment that enables us to identify
your level of academic English. This free assessment is available via DELNA.

Diagnostic English Language


Needs Assessment (DELNA)
DELNA is only available to students who have
accepted a place and enrolled at The University
of Auckland. It cannot be used to exclude you
from a particular programme and the results do
not appear on your academic record.

The screening is a 30 minute compulsory


assessment that includes a vocabulary task and a
text editing task. It enables us to quickly identify
whether or not you need assistance with the
demands of academic English. If you do require
assistance, you will undertake the second part of
the assessment. English Language Self Access
You should book your screening assessment
Centre (ELSAC)
during Orientation Week or the first week of ELSAC is the place where you can:
semester by going online to: www.delna.auckland.
• Get advice about your particular English
ac.nz/booking
language needs for university study
The diagnosis is only necessary if your screening
• Use a huge variety of English language
results suggest you need assistance with
resources
academic English language skills. This two-hour
assessment includes a listening, reading and • Come any time for as long as you like, Monday
writing task. It enables us to recommend to Friday between 9am and 5pm. Visit the
appropriate English language enrichment ELSAC space, real and virtual, and chat to
options. Siew, Rebecca or Penny — we’re all experienced
English language teachers.
If you do need to improve your skills, you will be
invited to discuss your needs with the DELNA ELSAC services are free for as long as you are
Language Adviser and guided to sources of enrolled at The University of Auckland.
effective English language enrichment within the
University.
ELSAC
For more information visit Level 1, Kate Edger Information Commons
www.delna.auckland.ac.nz Phone: +64 9 373 7599 ext 82134
Email: elsac@auckland.ac.nz
For more information visit
www.elsac.auckland.ac.nz

56 | 2010 Biomedical Science Handbook


Student support services
Service Location Contact details
Accommodation and O’Rorke Hall, 16 Mount Street +64 9 373 7599 ext 87691
Conference Services accom@auckland.ac.nz www.
auckland.ac.nz/accommodation
Careers Centre Room 001, The ClockTower www.auckland.ac.nz/careers
Early childhood services 28 Park Avenue Grafton +64 9 373 7599 ext 85894
Chaplain’s Office +64 9 373 7599 ext 87731
chapelsec@auckland.ac.nz
Disability service Room 036, The ClockTower (south +64 9 373 7599 ext 88808
wing) disabilities@aucklandac.nz
Mediator’s Office www.auckland.ac.nz/mdr
Equal Opportunities Level 1, The ClockTower (East Wing) +64 9 373 7599 ext 84923
www.eo.auckland.ac.nz
Student Financials Office Room 108, ClockTower +64 9 373 7599 ext 84422
www.auckland.ac.nz/fees
Health Services Level 3, Student Commons +64 9 373 7599 ext 87681
(including Counselling)

Dental Services Level 3, Student Commons +64 9 373 7599 ext 83860
International Students’ Auckland International, Old Choral +64 9 373 7513
Information Centre Hall int-questions@auckland.ac.nz
www.auckland.ac.nz/
international
Recreation Centre Building 314 +64 9 373 7599 ext 84788
17 Symonds Street www.auckland.ac.nz/recreation
Scholarships Office Room 012, The ClockTower +64 9 309 0789 ext 238
wave@auckland.ac.nz www.
ausa.auckland.ac.nz/wave
Student Advocacy Network AUSA House +64 9 309 0789 ext 238
3 Alfred Street wave@auckland.ac.nz www.
ausa.auckland.ac.nz/wave
Student Information Centre Room 112, The ClockTower 0800 61 62 63
+64 9 373 7599 ext 88199
studentinfo@auckland.ac.nz
Student Learning Centre Level 3, Information Commons +64 9 373 7599 ext 88850
Student loans and StudyLink 0800 88 99 00
allowances www.studylink.govt.nz
Student Resource Centre Science Centre, B01, Building 303 www.science.auckland.ac.nz
Students’ Association AUSA 4 Alfred Street +64 9 309 0789
ausa@auckland.ac.nz
www.ausa.auckland.ac.nz
University Book Shop (UBS) Kate Edger Building www.ubsbooks.co.nz

2010 Biomedical Science Handbook | 57


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58 | 2010 Biomedical Science Handbook


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2010 Biomedical Science Handbook | 59


Contact
Faculty of Science Student Centre
The University of Auckland
Private Bag 92019
Auckland 1142
New Zealand

0800 61 62 63
Phone: +64 9 373 7599 ext 87020
Txt: 5533
Fax: +64 9 373 7431
Email: scifac@auckland.ac.nz
Web: www.science.auckland.ac.nz

The Faculty of Science Student Centre


8:30am - 5pm Monday - Friday.
Students wishing to see the Science Advisors
regarding programmes or course advice,
planning and approval, may make an
appointment to visit during consultation hours.
To receive general advice or obtain further
information, students are free to drop in
throughout the day.

Physical Location
Ground Floor, Science Centre, Building 301
23 Symonds Street, Auckland

www.science.auckland.ac.nz