QUM
The Heart Foundation Pharmaceutical Roundtable members:
contents
background 4
the Heart Foundation Pharmaceutical Roundtable 4
about the project 4
about this report 5
some observations on stakeholders’ contributions 6
stages of QUM in cardiovascular health 7
cardiovascular medicine in Australia 8
risk factors for cardiovascular diseases 9
treatment of cardiovascular diseases 10
medicines used in the treatment of cardiovascular diseases 11
what is QUM 12
building blocks of QUM 13
general QUM actions and principles 13
before a cardiovascular event 15
1. identifying people at risk of cardiovascular disease 15
2. diagnosing cardiovascular diseases 17
3. prescribing lifestyle changes or medicines 18
4. dispensing medicines 22
5. counselling and education 24
6. beginning treatment 25
7. monitoring use of medicines and effects of treatment 28
8. adherence in the longer term 29
during a cardiovascular event 32
1. getting people to hospital 32
2. admission to hospital 32
3. interventions 33
4. providing information in hospitals during recovery 35
5. the short-term focus of hospitals 35
after a cardiovascular event 36
1. discharge—from hospital to home 36
2. coordinating rehabilitation services 40
3. integration of GPs and specialists 40
4. educating consumers and carers 41
5. support groups 41
2 / quality use of cardiovascular medicines in cardiovascular health
supporting environment 43
equity and access 43
links between sectors 43
general practice and practice nurses 47
policy and implementation 48
IT, connectivity and data exchange 50
training, education and information 52
further research, evaluation and modelling 57
missing in action 59
hospital administrators 59
private health insurers 59
nurses 60
support staff in general practice 60
pharmaceutical industry 61
carers 62
supermarkets and food retailers 62
the public media 62
notes 64
quality use of cardiovascular medicines in cardiovascular health / 3
glossary
ADGP Australian Divisions of General Practice
AHMAC Australian Health Ministers’ Advisory Council
AMA Australian Medical Association
APAC Australian Pharmaceutical Advisory Council
ASMI Australian Self-Medication Industry
CMC Complementary Healthcare Council
CMI Consumer Medicine Information leaflet
DAA Drug Administration Aid
DoHA Department of Health and Ageing (Commonwealth)
DUSC Drug Utilisation Sub-Committee
GP General Practitioner
HCO Health Consumer Organisation
HMR Home Medication Review
IT Information Technology
LDL Low Density Lipids
MBS Medicare Benefits Scheme
NATRUM National Return of Unwanted Medicines program
NGO Non-Government Organisation
NHMRC National Health and Medical Research Council
NICS National Institute for Clinical Studies
NMP National Medicines Policy
NPS National Prescribing Service
OTC Over-The-Counter Medicines
PBAC Pharmaceutical Benefits Advisory Committee
PBS Pharmaceutical Benefits Scheme
PGA Pharmacy Guild of Australia
PHARM Pharmaceutical Health And Rational use of Medicine
PSA Pharmaceutical Society of Australia
QUCVM Quality Use of Cardiovascular Medicines
QUM Quality Use of medicine
RACGP Royal Australian College of General Practitioners
RACP Royal Australasian College of Physicians
RPBS Repatriation Pharmaceutical Benefits Schedule
SHPA Society of Hospital Pharmacists of Australia
SNAP Smoking, Nutrition, Alcohol and Physical Activity
WHO World Health Organisation
4 / quality use of cardiovascular medicines in cardiovascular health
background
T H E H E A R T FO U N D A T I O N P H A R M A CE U T I C A L R O U N DT A B L E
The mission of the Roundtable is to reduce suffering and death from heart, stroke and
blood vessel disease in Australia. It pursues this goal by:
• funding research
• initiating and supporting cardiovascular health initiatives of interest to both
industry and the Heart Foundation
• working to keep cardiovascular health issues high on the national agenda.
A B O U T T H E P R O J E CT
In July 2005, the Pharmaceutical Roundtable commissioned RED3 to explore Quality
Use of Cardiovascular Medicines (QUCVM)—provisionally defined as “selecting the
right coronary heart disease treatment or prevention option at the right time and
adhering to it in the right way”. Specific goals of the project were to:
• identify barriers to QUCVM
• helping the Roundtable develop strategies to overcome these barriers
• prioritise actions to help the Roundtable achieve QUCVM.
This project built on previous research undertaken by RED3 for the National Medicines
Policy and The Pharmaceutical Alliance (reported in Views of Quality Use of Medicines1).
This report also comes in the context of QUM activities in other major disease areas by
PHARM, particularly asthma and diabetes2.
RED3 conducted the research in three broad stages. First its researchers interviewed
nearly fifty key stakeholders in cardiovascular health and Quality Use of medicine.
quality use of cardiovascular medicines in cardiovascular health / 5
Next, it collated the contributions of these stakeholders and presented the results to a
National Stakeholder Workshop, held in Canberra on 25 November 2005. The event
was structured to fill gaps in the work to date, correct misunderstandings and
mistakes, and to add further detail. It also sought suggestions for practical action to
achieve QUM in Cardiovascular Health. Finally, RED3 combined the products of the
workshops with findings reported in the research literature. This work forms the basis
of this report.
The project also included a separate research strand for Indigenous Australians. This
will be reported separately, as the needs, concerns and resources of Aboriginal and
Torres Strait Islander communities are unlike those of other Australians.
At the core of this report are 128 suggestions for action to achieve Quality Use of
medicine in Cardiovascular Health. Around these suggestions, we have provided
contextual information, which explains the reasons participants made these
suggestions, along with evidence from the research literature where available.
Some suggestions are large; some are small. Some are technical; some are
commonsense. Some are complex; some are simple. Some are novel; some have been
made before but have not been implemented. Some are focussed and precise; others are
so general it would be better to call them ‘guiding principles’. For some of the more
incomplete ideas, we have extrapolated the practical consequences, but otherwise we
have presented participants’ suggestions much as they were given to us, that is,
without trying to give them a consistency they did not have for participants.
All suggestions include a rank (from ★ to ★★★★★) indicating the impact that
stakeholders believed the action might have. In some places, stakeholders did not
discuss impact. In these instances we have suggested its potential based on research or
principles of continuity. These are marked with ✩ rather than ★. Many of the
suggestions are beyond the Roundtable’s ability to achieve in isolation. This is because:
• many require activity by stakeholders who are not members of the Roundtable
• some suggestions would place large demands on others
• some suggestions are beyond the Roundtable’s means (such as changing
infrastructure, funding, equity, and access).
6 / quality use of cardiovascular medicines in cardiovascular health
S O M E O B S E R V A T I O N S O N S T A K E H O LDE R S ’ CO N T R I B U T I O N S
Our discussions with stakeholders were organised around the journey that patients
take through cardiovascular disease. This is also the basis for organising the material in
this report. The main stages in this journey are shown on the next page.
The comments and suggestions from participants in this project were not spread
evenly over this journey. There were some notable gaps we need to point out.
1. Most attention went to the initial stages of cardiovascular disease, including
assessment of cardiovascular risk and initiation of treatment—along with
information and education. Almost absent was discussion of the adherence of
consumers to long-term treatments. This is broadly consistent with approaches to
QUM taken in the past decade.
2. Participants gave more attention to the use of medicine in the community than in
hospitals, and there was no discussion at all of private hospitals.
3. Most concern was with medicine use at particular instants, usually moments of
crisis; rather rare was QUM as a continuum or a large system of interlocking parts.
This may reflect the prevailing mindset of the health community, which remains
focussed on acute episodes rather than managing chronic conditions.
4. We specifically engaged groups that have not been much involved in QUM to this
point—such as allied health workers and specialist physicians. Even so, we did not
generate much detail concerning their work and potential contributions to
cardiovascular health. Chiefly, this is because existing stakeholders have still to
learn about these health professions and how they might contribute to QUM. Some
groups declined to be involved in the project—most notably carers (who have
proved difficult to engage in QUM generally).
5. Some groups with a potential role in QUM were hardly mentioned by those
consulted. They included private health insurers, hospital administrators, support
staff in general practice, the mass media, supermarkets (as the main suppliers of
food), and the marketing sections of pharmaceutical manufacturers (as one of the
chief producers of information on medicines). These are discussed on pages 58–62.
We stress that the points made in this report are only suggestions, and are not binding
on either the Heart Foundation or members of the Roundtable.
quality use of cardiovascular medicines in cardiovascular health / 7
before an event
identifying diagnosing
during an event
people at risk disease
1A 1B
cardiovascular
event
lifestyle dispensing
3A 3B
changes 2 admission
medicine
4
counselling and
education intervention
3
taking
5
medicine
4 recovery
monitoring use
6
and effects
5 discharge
7 adhering
after an event
1A 2A 3 4
Even for those who survive or do not suffer an acute event, cardiovascular diseases are
the leading cause of long-term disability. In 1998, over 1.1 million Australians were
affected—nearly a third of all people living with a disability.
The burden of cardiovascular diseases is growing: in the 1990s, the incidence of heart,
stroke and vascular conditions rose by 18.2 per cent. The following table shows the
number and percentage of Australians who self-reported being affected by major
cardiovascular illnesses in the 2001 National Health Survey. There is no data available
for incidence of peripheral vascular disease, rheumatic heart disease or congenital heart
malformations.
persons percent
Coronary heart disease 355,600 1.9%
Heart failure (estimated) 300,000 1.6%
Stroke 217,500 1.2%
The burden of cardiovascular disease is not spread evenly through the Australian
community. Women are slightly more likely than men to have some form of
cardiovascular disease, but men are over one-third more likely to be hospitalised for
heart, stroke or vascular disease. People in the most disadvantaged socio-economic
groups are over twenty per cent more likely than people in the most socioeconomically
quality use of cardiovascular medicines in cardiovascular health / 9
advantaged groups to have a risk factor, a higher incidence of disease, and death due to
cardiovascular disease3. People living in regional and remote areas are more likely to die
of cardiovascular diseases.
R I S K FA CT O R S FO R CA R D I O V A S C U LA R D I S E A S E S
The following table shows prevalence of the main risk factors in Australia for those 18
years old and over in 20015.
In 2001, over 92 per cent of Australians had at least one risk factor, and 25 per cent
had three or more5.
men women persons
number of risk factors (%) (%) (%)
none 6.1 9.5 7.8
one 20.5 26.3 23.4
two 29.8 29.3 29.6
three 25.6 20.4 22.9
four 12.9 10.0 11.4
five or more 5.2 4.5 4.8
10 / quality use of cardiovascular medicines in cardiovascular health
T R E A T M E N T O F CA R DI O V A S CU LA R DI S E A S E S
Cardiovascular diseases accounted for approximately 11 per cent of all problems
managed by GPs in 2002–2003.
Cardiovascular diseases were the principal diagnosis of 7 per cent of all hospitalisations
in 2001–2002, and 9.8 per cent of total hospitalisations3. In 2001–2002, there were:
• 120 coronary care units and 21 cardiac surgery units in public hospitals
• 26 coronary care and 23 cardiac surgery units in private hospitals3.
The primary treatment for all people at risk of cardiovascular diseases remains risk
reduction through lifestyle modification, and secondly by medicine. The following table
shows treatments demonstrated to reduce the risk of cardiovascular morbidity and
mortality from ischaemic heart disease6.
Relative risk reduction
Smoking cessation 50%
Regular physical activity 50%
Reducing blood pressure 15–25%
Reducing cholesterol with diet and statins 30–50%
Antiplatelet therapy with low-dose aspirin 25%
Beta-blockers post myocardial infarction 20–30%
ACE inhibitors post myocardial infarction 20–26%
Controlling blood glucose 14%
quality use of cardiovascular medicines in cardiovascular health / 11
M E D I CI N E S U S E D I N T H E T R E A T M E N T O F CA R D I O V A S C U LA R D I S E A S E S
The following table shows prescription medicines used to treat cardiovascular diseases
in the community in Australia in 20003.
scripts a cost b
medicine role in treatment (’000s) ($m)
Blood pressure-lowering drugs
ACE inhibitors limit heart enlargement after an attack, 14,764 421
relieve symptoms
Calcium channel reduce blood pressure and angina 8,729 213
blockers
Beta-blockers reduce blood pressure, reduce angina 4,542 62
pain, reduce risk of further heart attacks
Diuretics reduce blood pressure, symptom relief 3,525 42
Other 987 18
Total blood pressure-lowering drugs 32,547 755
Lipid-lowering drugs
Statins reduce blood LDL cholesterol and blood 10,744 618
Fibrates triglycerides 448 20
Resin binders 46 2
Other 21 0.5
Total lipid-lowering drugs 11,259 641
Other drugs
Nitrates relieve and prevent angina symptoms 2,691 56
Antiarrhythmics restore normal heart beat in arrhythmia 532 16
Inotropes increase the strength of heart 715 6
contractions
Peripheral vasodilators 10 0.2
Total other drugs 3,949 78
Antithrombotic drugs
Anticoagulants prevent formation of blood clots 1,911 20
Antiplatelets prevent formation of blood clots 1,438 49c
Thrombolytics dissolve blood clots 1 2
Total antithrombotic drugs 3,350 72
Total heart, stroke and vascular drugs 51,104 $1,546m
a Prescription drugs subsidised under the PBS and RPBS, and non-subsidised prescription drugs.
b Includes government and patient costs for drugs listed in the PBS only.
c Probably a gross underestimate of actual cost, as over-the-counter aspirin is not included.
12 / quality use of cardiovascular medicines in cardiovascular health
what is qum
A recurring problem for the implementation of Quality Use of Medicine has been
uncertainty about the definition of QUM. We found much the same in this project.
Consequently, we advise the Roundtable against any changes to the definition or
terminology that might fragment those tenuous understandings of QUM that have
been achieved to date.
✩ 1 SUGGESTION FOR THE ROUNDTABLE—change terminology from ‘Quality Use
of Cardiovascular Medicines’ (QUCVM) to ‘Quality Use of medicine in
Cardiovascular Health’ (QUM in CVH).
3. Using medicines safely and effectively to get the best possible results by
• monitoring outcomes
• minimising misuse, over-use and under-use
• improving people’s ability to solve problems related to medication, such as
negative effects or managing multiple medications.
quality use of cardiovascular medicines in cardiovascular health / 13
B U I LDI N G B LO CK S O F Q U M
The National Strategy for Quality Use of Medicines outlines six ‘building blocks’ necessary
to achieve QUM7. They apply to all stakeholders and care settings. They are:
• policy development and implementation
• facilitation and coordination of QUM initiatives
• provision of objective information and assurance of ethical promotion of
medicines
• education and training
• provision of services and appropriate intervention
• strategic research, evaluation and routine data collection.
Although stakeholders’ suggestions covered all six areas, the building blocks themselves
—like the formal definition of QUM—are not widely recognised or used.
G E N E R A L Q U M A CT I O N S A N D P R I N CI P LE S
As noted in the Background, there were a number of broad principles mentioned
throughout the project, which are too broad to be actionable, but illustrate the type of
approach people wanted QUM in Cardiovascular Health to take.
14 / quality use of cardiovascular medicines in cardiovascular health
There was criticism that not enough is being done—by Australian and State
governments in particular—to promote and support primary prevention.
1. I DE N T I FYI N G P E O P LE A T R I S K O F CA R DI O V A S CU LA R DI S E A S E
Overwhelmingly, the greatest need in cardiovascular health seen by those we consulted
is identifying people at risk, in order to initiate appropriate preventative management.
Many of the key risk factors for cardiovascular disease go undiagnosed and untreated.
For example, the AusDiab study of 11,250 Australians in 1999–2000 found that over
half of people with hypertension were not being treatment for it9. Of these people, 53.5
per cent were at a high absolute risk of cardiovascular disease—which would be
equivalent to about 8 per cent of the Australian population. (These figures may have
improved somewhat in the five years since as management of lipid disorders by general
practice has increased by 24 per cent10.)
Participants felt that the greatest barrier to risk screening is getting Australians
—particularly men—to a health professional. Even well-coordinated screening
programs, such as BreastScreen and Pap screens, only attract around two-thirds of
target populations8. Attendance in these programs is also noticeably lower in remote
areas. Some participants suggested that it may be necessary to provide incentives to
consumers to undertake screening. Apart from getting people to health professionals,
the other great barrier to screening is generating time for health professionals to carry
out a comprehensive risk assessment, as well as appropriate funding for such a scheme.
There are already a number of cardiovascular risk calculators11, but some studies
suggest that many doctors do not use them. Reasons given for this include:
• doctors prefer to rely own their own clinical judgement (which is itself a problem,
as studies have found that Australian doctors routinely over-estimate the absolute
risk of a cardiovascular event12)
• current risk calculators are poorly integrated with practice software
• there are inconsistencies between the calculators and various regulations
(particularly PBS guidelines around use of lipid-lowering medicines), and
• doctors feel that the current factors assessed are incomplete13.
At best, most doctors use the existing tools for patient education.
Some participants stressed that risk assessment needs to take into account not only
patient’s physical state, but also their psychosocial conditions. There is a demonstrated
association between coronary heart disease and depression, limited social support and
social isolation (although apparently not with anxiety, panic, hostility, or work-related
stress)14.
quality use of cardiovascular medicines in cardiovascular health / 17
a. Work with other chronic disease groups to develop practical tools for
general practice to assess risk of chronic disease.
c. Develop and deliver training for GPs, specialists and nurses in the use of
the assessment tools.
f. Work with AMA, RACGP and ADGP to reduce other GP workload and
administration, to make screening and administration manageable.
h. Explore measures that would help make risk assessment highly accessible
—particularly to people from lower socio-economic groups, in remote
areas, and in areas with limited access to health services. Options might
include mobile screening buses and specialised risk assessment clinics.
2. DI A G N O S I N G CA R D I O V A S C U LA R D I S E A S E S
Generally, stakeholders were comfortable that general practitioners and specialists
have the knowledge to correctly diagnose cardiovascular disease. This is at odds with
research, which has found that heart failure, for example, is under-diagnosed and
treatments under-utilised15,16.
One problem is that some general practitioners treat the PBS Schedule as a guide to
clinical decision-making around the selection of medicines (not its intended function).
18 / quality use of cardiovascular medicines in cardiovascular health
A second problem can occur when a patient sees several doctors and receives
conflicting advice from them. Some studies have found this happens for up to a quarter
of Australian patients generally17—a figure that is probably higher for patients with
cardiovascular disease, as they are more likely to seek a second opinion. Conflicting
advice might be partly reduced through use of a transferable medical record and better
communication between doctors (see pages 50–51).
3. P R E S CR I B I N G LI F E S T YLE CH A N G E S O R M E DI CI N E S
There is evidence that many key medicines that are effective in reducing the risk of
cardiovascular disease—including ACE inhibitors16, beta-blockers16,18 and lipid-lowering
medicines19—are being under-prescribed
• find out how to use medicines and other treatments effectively (in
particular, how to take medicines correctly, what results to expect,
when to expect results, how to monitor them, and what to do if
treatment does not work as expected)
• monitor their treatments and, if medicines do not work as expected,
report to the prescriber.
A second concern for many participants was that the majority of patients do not tell
their general practitioners and specialist physicians about complementary medicines
they are taking, increasing the chances of interactions and adverse effects. Recent
research has found that over 50 per cent of patients use complementary or alternative
medicines, and 57 per cent of these did not report using medicines to their doctor20.
Two other ways of improving disclosure of medicines to doctors when prescribing are:
• using a centralised medical record—including a medicines record (see page 50)
• getting all patients to prepare a medicine record sheet and review it regularly with
their prescribers and dispensers. (Several forms have been developed—such as the
NPS’s Medimate and Medisafe and a PSA sheet—but they are not widely used.)
8 Develop a medicines record for patients to complete, and get it widely ★★★★
distributed and used by both consumers and health professionals.
patients have several conditions or are taking several medicines. The information
available to guide them is very fragmented and difficult to access as a whole. There is
growing evidence that guidelines are not being translated into clinical practice22.
★★★★ 10 Develop an easily-searchable portal or website of all medical evidence,
guidelines and treatment options. Access needs to minimise the burden on
health professionals, and material must be easy to remember and act on.
Between 1999 and 2005, general practitioners substantially increased their counselling
on nutrition and weight loss: up from 3.8 per 100 visits in 1999–2000 to 5.3 per 100 in
2004–2005, with the largest increase coinciding with the introduction of the SNAP
guidelines in 200123.
While there is a large amount of basic information on healthy eating and exercise, it is
highly fragmented and frequently inconsistent. For example, the DoHA ‘Healthy
Active’ campaign urges consumers to eat 2 fruit and 5 vegetables a day, while Nutrition
Australia encourages Australians to eat around 30 foods each day24. Much existing
lifestyle advice does not take into account the differing dietary requirements of people
with chronic diseases (such as limiting fluid intake or reducing salt), or explain how to
balance competing demands for people with comorbidities. Likewise, exercise programs
tend to focus on the impact of physical activity on individual diseases, and ignore the
contributions of exercise to general well-being and mental health.
★★★ 12 MAJOR CHRONIC DISEASE GROUPS AND NUTRITION AUSTRALIA—develop
consistent advice on food and exercise for people with chronic diseases
—including adjustments that should be made for people with specific
diseases and combinations of diseases.
quality use of cardiovascular medicines in cardiovascular health / 21
As noted earlier, a number of studies have found that key risk-lowering medicines are
under-used by general practitioners16,18,19. Research suggests that the main reason for
this is because GPs are:
• excessively concerned about side effects
• concerned about the effects of these medicines on co-morbidities
• unaware or unconvinced about the benefits of medicines
• lacking experience or confidence in initiating and titrating medicines.
15 SUGGESTION FOR NICS AND NPS—continue and extend guidance for GPs on ✩✩✩✩
appropriate use of cardiovascular medicines.
A number of those we interviewed said they felt many general practitioners and
specialists were poorly informed about the benefits and risks of complementary and
alternative medicines—either dismissing them or under-estimating their potential.
★★ 19 SUGGESTION FOR NICS, NPS, RACGP, RACP AND DIVISIONS OF GENERAL
PRACTICE—provide training for general practitioners and specialist doctors
about the uses, benefits and risks of complementary medicines, so they can
advise consumers constructively.
4. DI S P E N S I N G M E DI CI N E S
There was some concern that pharmacists are not identifying contraindications and
medicine interactions—particularly with OTCs and complementary medicines.
★★★★ 20 SUGGESTION FOR PHARMACISTS—specifically ask consumers about their use
of complementary, OTC and prescription medicines when dispensing; and
check for and advise consumers on possible adverse interactions.
quality use of cardiovascular medicines in cardiovascular health / 23
21 Develop a medicines record for consumers to complete, and get it widely ★★★★
distributed and used.
Some of those we interviewed were concerned that consumers can easily become
confused by pharmacists’ labels on prescription medicines—particularly when buying
medicines from several different pharmacists—because of inconsistent practices and
difficulty consumers can have reading pharmacist labels. (Pharmacists’ labels are
controlled under State and Territory poisons regulations.)
Several people interviewed were concerned that an increasing number of consumers are
ordering medicines on the internet—especially from overseas sources. (We have not
been able to secure data to confirm this.) People had concerns about:
• the quality and safety of such medicines—especially from overseas sources (where
there is a trade in ‘fake pharmaceuticals’)
• the lack of counselling provided at the time of dispensing
• CMI and other consumer information not being provided
• the lack of a record of medicines dispensed to a consumer.
24 / quality use of cardiovascular medicines in cardiovascular health
We were told that many doctors and pharmacists are unaware of Regulations 24 and 25
of the PBS Schedule, which permit dispensing of larger or longer-term scripts. Some
people felt that better use of these provisions could reduce consumer costs, by reducing
the need for travel to doctors and pharmacies—particularly for people in remote areas.
Not everyone we interviewed supported these schemes, as they could also reduce
contact with doctors and limit opportunities for monitoring a patient’s condition.
Some people we interviewed also felt it could lead to abuse of medicine.
★★ 25 SUGGESTION FOR MEDICARE AUSTRALIA—Inform doctors of prescribing and
dispensing options that help consumers manage the cost of medicines and
treatment.
5. CO U N S E LLI N G A N D E DU CA T I O N
A major concern for many we consulted is that some patients do not understand what
their doctor tells them. Research for the Department of Veterans Affairs reported that
patient confusion was responsible for 61 per cent of medicine-related problems after
discharge from hospital27. Similar findings have been reported in general practice28.
Consumer research has also repeatedly found that, while consumers are generally
satisfied with the technical knowledge of doctors, they felt that general practitioners’
greatest weakness is in their communication skills29. The problem is not just a matter
of skill, but also a lack of time to counsel patients, particularly when managing chronic
diseases.
For cardiovascular diseases specifically, there is concern that patients have only a vague
idea about the course of the disease and how treatment helps—particularly when
consumers experience no symptoms. This lack of knowledge lowers adherence to
treatment.
★★★★★ 27 SUGGESTION FOR THE HEART FOUNDATION—continue to develop and
distribute information for consumers on:
• specific cardiovascular diseases—their aetiology and progress
• treatment options and how they work.
There is broad criticism that CMI are not being delivered to many consumers—possibly
most consumers—even though pharmacists receive a payment for each CMI provided.
Many stakeholders felt that the Pharmacy Guild guidelines for providing CMI are
quality use of cardiovascular medicines in cardiovascular health / 25
inadequate. The most recent review of CMI dispensing found only 12 per cent of
consumers received a CMI30. Also, many professionals—including nurses and specialist
doctors—do not know that CMI exist. There is a widespread belief that consumers do
not know to ask for CMI.
6. B E G I N N I N G T R E A T M E N T
Many general practitioners are especially concerned about titrating medicines (that is,
starting patients on a low dose then slowly increasing to full therapeutic strength). The
result is that the bulk of patients are on below-target doses31. Reasons that doctors are
concerned about titrating medicines include:
• uncertainty about dose regimens
• uncertainty about appropriate target doses
26 / quality use of cardiovascular medicines in cardiovascular health
All of these benefit from social and family support. Changes to diet in particular are far
more effective if everyone in the patient’s household adopts healthy eating habits, and
if healthy eating options are easily accessible and affordable at work.
★★ 35 SUGGESTION FOR EMPLOYERS—provide healthy food in staff canteens and
healthy lifestyle programs for staff.
A perception of some participants in this project was that many consumers do not
know how to make healthy food choices—for example, selecting fruit and vegetables,
or making use of dietary information. (As noted earlier, basic nutritional information is
fragmented, and different organisations make recommendations that sometimes
quality use of cardiovascular medicines in cardiovascular health / 27
conflicts.) Some participants also felt that there was a widespread belief that healthy
eating is expensive and time-consuming.
Apart from advice to individual consumers and their carers, participants also wanted to
see ‘environmental’ campaigns, promoting healthy lifestyles in the wider community.
38 Link cardiovascular prevention campaigns with the DoHA ‘Healthy Active’ ★★★
(Go for 2 & 5) campaign.
39 SUGGESTION FOR DOHA—re-fund the ‘Life Be In It’ public campaigns and ★★★
activities and other healthy living campaigns.
People we interviewed said many consumers and groups had difficulty obtaining
healthy food at a reasonable price. Groups particularly affected are:
• people with low incomes
• people in remote areas
• the elderly
• people that frequently ate away from home—such as those in the transport sector.
There was also concern that many consumers have only a vague notion of what ‘healthy
food’ involves and how to obtain it. While mnemonics such as the ‘food pyramid’ are
widely recognised, it is not clear that many consumers actually use these tools when
shopping or planning their meals.
A key group that several stakeholders wanted to draw into cardiovascular health are the
food retailers and suppliers—particularly supermarkets. Some of those interviewed felt
that the balance of foods in shops favoured less-healthy food options, simply because
these occupied the bulk of shelf-space.
One group we interviewed suggested that the distinction between medicines and some
foods was becoming blurred with the introduction of ‘fortified foods’—such as milk
with added minerals, margarine with sterols, bread with added vitamins and so on.
28 / quality use of cardiovascular medicines in cardiovascular health
Nutritionists and dieticians were divided on the virtues of these foods and the health
claims made about them.
While there has been great public attention recently on obesity, less recognised is
widespread malnutrition amongst the elderly.
A final problem raised frequently in our discussions was that, even if people could
obtain healthy ingredients, the number of people who cook is believed to be
declining—and the number eating pre-prepared meals is growing. Many schools no
longer teach children cooking or basic home economics, and some people interviewed
thought that many young people do not learn to cook at home. Cooking also takes
time, which can be difficult for people working shift hours or that have busy lives.
★★★★ 42 SUGGESTION FOR DEPARTMENTS OF EDUCATION—have cooking classes in all
high schools, to encourage preparation of healthy meals.
7. M O N I T O R I N G U S E O F M E D I CI N E S A N D E FFE CT S O F T R E A T M E N T
Several people consulted were concerned about monitoring medicine levels, particularly
when patients first begin new treatments. In particular, some felt that many
consumers do not appreciate the importance of monitoring their Warfarin and diuretic
levels. (Several participants also felt that there were problems with the current booklet
for monitoring Warfarin.)
★★★ 43 SUGGESTION FOR THE SAFETY AND QUALITY COMMISSION—Redesign the
Warfarin book.
There was strong support for the value of Home Medication Reviews (HMRs) for
checking that medicines are being used appropriately, identifying problems with use,
tracking medicine use, identifying potential interactions, finding expired medicines,
identifying patients who are hoarding, and reducing over-prescribing. HMRs have been
shown to result in net cost savings to government32. Participants said that some
specialists are particularly keen to have an HMR conducted for their patients before
surgery (but are not currently authorised to order them). HMRs are also seen as
particularly valuable after discharge from hospital to increase patient adherence and
improve medication management.
quality use of cardiovascular medicines in cardiovascular health / 29
44 SUGGESTION FOR DOHA, GPS AND THE PHARMACY GUILD—increase use of ★★★★
Home Medication Reviews, particularly before admission to hospital and
at discharge. This will involve:
• increasing the number of pharmacists trained to perform HMRs
• encouraging GPs to order HMRs where appropriate, and use the
results
• giving specialists the authority to order HMRs.
One value of electronic health records (discussed on page 50–51), is that tracking
under-use and overuse would become much simpler, especially if they were linked with
dispensing records.
8. A DH E R E N CE I N T H E LO N G E R T E R M
There is widespread agreement that current adherence to preventative treatments
—both medicinal and lifestyle—is far from optimal. Adherence is believed to be
particularly low among asymptomatic patients and those who have experienced no ill-
effects. Patients’ adherence tends to increase only after a cardiac event or stroke brings
the disease to their attention. Since many of the common medicines prescribed for
cardiovascular disease require minimum concentration levels in the body before they
have any effect, widespread non-adherence could mean that a significant part of
medicinal treatment is under-performing or wasted.
It was striking how little attention those we interviewed gave to adherence. This
appears to reflect a similar absence in the larger medical environment. A recent
Cochrane Review noted that:
with the astonishing advances in medical therapeutics in the past two decades, one
would think that studies of the nature of non-adherence and the effectiveness of
strategies to help patients overcome it would flourish. On the contrary, the literature
concerning interventions to improve adherence with medications is surprisingly weak33.
The WHO report identified the following factors that impact on patients’ adherence to
cardiovascular treatments:
• conditions where there are no symptoms (such as high blood pressure)
• the long-term nature of cardiovascular diseases
• access barriers
• patient’s acceptance of the disease and perception of the risk involved
• patient’s knowledge of cardiovascular disease
• support from carers and family members
• awareness of the costs and benefits of different treatment options
• degree of the patient’s involvement in monitoring
• relationship between the patient and health care providers (difficult when the
patient does not have a regular doctor, or has limited funds for health care)
• the patient’s tolerance for medicines
• keeping medical appointments
• cost of medicines—especially where the patient has co-morbidities or is prescribed
a number of medicines
• complexity of the treatment regimen (frequency of dosing, number of other
medicines being used, changes to medicines).
Doctors and other health care professionals need advice on how to distinguish between
non-adherence to treatments and the failure of treatments.
Strategies for doctors that have been found to improve medicine taking in
cardiovascular treatment include:
• prescribing the fewest number of doses to be taken daily (the more doses a person
has to take, the more likely they are to miss a dose)
• considering other medicines that the patient is taking
• explicitly scheduling when patients are to take their medicine
• helping patients select reminders and cues to take their medicines38.
45 SUGGESTION FOR THE ROUNDTABLE, NPS, NICS, RACGP AND HEALTH ✩✩✩✩✩
EDUCATORS—develop a resource kit and training for general practice to
help GPs improve adherence to cardiovascular treatments (and for other
chronic diseases).
Participants did not discuss managing acute episodes, such as angina attacks.
1. G E T T I N G P E O P LE T O H O S P I T A L
A problem with all cardiovascular events is getting people to hospital soon enough for
treatment to be possible. Unfortunately, there are many people who do not seek help
until it is too late—and they either die or sustain permanent physical damage.
Approximately a quarter of people die within an hour of their first symptoms, and the
risk is even greater for people that have experienced a previous heart attack. Currently,
half of all heart attack deaths occur before the person reaches hospital3.
★★★★★ 48 SUGGESTION FOR THE HEART FOUNDATION—Educate consumers to recognise
symptoms of cardiovascular events, and what action to take in response.
2. A DM I S S I O N T O H O S P I T A L
When a person arrives at hospital—either by ambulance or by themselves—their
condition is assessed in the Emergency department and then they are admitted to an
appropriate unit. Leaving aside known problems with identifying cardiovascular
events, for QUM the key part in the admission process is checking the patient’s
medicines. Developing this list is often difficult because:
• many patients cannot remember what medicines they are using
• after a cardiac event or stroke, the patient may be unable to speak
• patients may not know the names of their medicines—and admissions staff may
have to guess based on the patient’s medical conditions
• most patients do not keep a medicines list with them
quality use of cardiovascular medicines in cardiovascular health / 33
• patients or family members may not think to bring medicines when they come to
hospital
• some do not bring packages with them, making identification of tablets difficult
• ambulances sometimes advise patients against taking their medicines to hospital,
because some facilities confiscate or destroy consumers’ medicines
• many patients do not mention OTCs or complementary medicines they are using.
Each hospital has different processes for developing a medicines list—sometimes it will
be done by a pharmacist and sometimes by a nurse. Hospitals also vary in how they
record information for future reference—especially upon discharge. Some hospital
pharmacists will contact the patient’s GP or community pharmacist for help when
developing the medicine list—but they are aware that records can easily be incomplete.
Participants we interviewed felt that the best solution was a transferable or centralised
medicine record (see pages 50–51). In the absence of this, current processes could be
improved by standardising the data gathered across all hospitals. (In 2005, APAC
released its revised Guiding principles to achieve continuity in medication management.)
49 SUGGESTION FOR DOHA, STATE DEPARTMENTS OF HEALTH AND THE QUALITY AND ★★★★★
SAFETY COMMISSION—
(1) develop standard procedures and a standard sheet for recording
patients’ medicine details at admission
(2) disseminate the recording sheet and protocols nationally, and provide
training in their use.
3. I N T E R V E N T I O N S
Hospital interventions can be divided broadly into surgical and pharmacological.
Participants in this project did not raise issues concerning surgery—such as pacemaker
implants, defibrillators, bypass graft surgery, surgical ventricular restoration, heart
transplant and stents. The medicines relevant to cardiac surgery and recovery are:
• for managing tissue grafts or prosthetic devices
• for managing risk factors—blood clotting, high blood pressure and lipid levels
• for managing pain
• anti-depressants.
Specialist physicians will be more difficult to engage than GPs because—apart from the
Royal Australian College of Physicians—there are few networks available for reaching
them, and there is nothing comparable to the Divisions of General Practice. Even the
College is divided into 25 specialities (including cardiology and gerontology).
The variety of specialities involved in the care of patients with several comorbidities
can also cause problems. Specialists tend to focus on their own disease areas, rather
than pursuing holistic treatment. Consequently cardiologists, for example, may not be
aware of the interactions of the medicines they prescribe with those used to treat other
illnesses.
A problem for patients’ recovery after discharge is that each hospital has its own
formulary (because hospital pharmacies are funded separately from the PBS). Hospitals
may use medicines that are unobtainable or expensive for consumers after discharge.
In particular, they may use medicines not listed on the PBS. Specialists may be
prescribing medicines that are expensive or unavailable after discharge. When the
patient is discharged, their GP may need to change the medicines they were given in
the ward—and some patients are unwilling to change prescriptions written by their
specialist. This can lead to unnecessarily high costs, patients not filling scripts, double
dosing (as patients take medicines prescribed by both their GP and specialist), and
lower adherence. An area hospital pharmacists could help is advising doctors on the
availability and cost of medicines for consumers after discharge.
★★★★ 52 SUGGESTION FOR PBAC AND HOSPITAL PHARMACIES—develop better alignment
between hospital formularies and PBS Schedule.
★★★★ 53 SUGGESTION FOR PBAC, NPS AND RACP—make specialists aware of medicines
available on the PBS, and the cost implications of their hospital
prescribing. Encourage specialists to select medicines that will minimise
the need for changes after discharge.
quality use of cardiovascular medicines in cardiovascular health / 35
4. P R O V I DI N G I N FO R M A T I O N I N H O S P I T A L S DU R I N G R E C O V E R Y
In hospitals, it is usually nurses that provide the bulk of information to patients and
families—both formally and informally. Consumers and support groups we
interviewed felt that patients were more comfortable talking candidly with nurses than
doctors, and were freer in asking them questions. Nurses also ‘translated’ information
provided by doctors, explaining the practical, day-to-day implications of treatment in a
non-technical manner.
In practice, ward nurses are often also the gatekeepers of written information
—whether written in-house or by external groups such as the Heart Foundation. This
role does not appear to have been widely appreciated, and nurses are often not
informed of resources available or are uncomfortable providing some materials.
Consequently, many written resources do not reach hospital patients or are underused.
There are standards for the supply of CMI in hospitals40, but it is unclear how closely
they are followed.
5. T H E S H O R T - T E R M FO CU S O F H O S P I T A LS
A comment made by several people was that, because the focus of hospitals is not
chronic disease management—and they are funded chiefly for acute care—hospitals
often take a short-term or episodic view of cardiovascular health. A challenge seen by
many we interviewed was to shift the traditional acute care model of hospitals, and
integrate it into the longer-term holistic management needed to treat chronic illnesses
like cardiovascular disease.
This short-term focus could also exacerbate problems caused by cost-shifting which
result from the funding split between State and Commonwealth governments. For
example, in many hospitals, public patients are given bare metal stents, whereas
private patients are given coated stents. Because bare metal stents need to be replaced
more often than coated stents, this practice costs both consumers and public funding
more in the longer term. But, in the short term, it is cheaper to the hospital performing
the operation.
36 / quality use of cardiovascular medicines in cardiovascular health
An essential part of on-going care is prevention. The QUM issues that participants
raised about it are much the same as they were for treatment before a cardiovascular
event.
1. DI S CH A R G E — FR O M H O S P I T A L T O H O M E
There is general agreement that one of the biggest sources of problems in the use of
cardiovascular medicines—and treatment generally—is at discharge: in the transition
from hospital to home or residential care. This parallels findings of a 2001 study, which
found poor compliance with APAC’s 1998 National guidelines to achieve the continuum of
quality use of medicines between hospital and community41,42. (The original guidelines have
been revised and re-released as the Guiding principles to achieve continuity in medication
management.)
In public hospitals, with pressure to clear beds quickly, discharge can be difficult to
schedule and is often rushed. Discharges are frequently done by junior medical staff,
quality use of cardiovascular medicines in cardiovascular health / 37
and often hospital pharmacists are not involved. Discharge procedures vary greatly,
and depend on whether the patient is in a cardiac unit or a general ward.
A 2001 intervention study found that, before the intervention, only 55 per cent of
patients with acute coronary syndrome had a clinical pharmacist review their
medicines before discharge.
There is broad agreement that electronic or transferable health records would be the
best way of reducing the loss of information at discharge. In the absence of electronic
records, an alternative is to improve and standardise discharge processes. (This could
tie in with the Quality and Safety Commission’s work on the National In-Patient
Medication Chart in hospitals and Common Medication Chart for residential aged
care.)
As noted earlier, each hospital has its own formulary, and they vary considerably in the
medicines they stock. Generally, they are not aligned with the PBS Schedule. This
becomes a problem when patients are discharged, as many GPs do not like to change
what specialists have prescribed (because it reduces adherence). This can result in
significant on-going costs to consumers. And, if GPs do make changes, we were told
that many patients continue to take what their specialist prescribed, along with their
new medicines—which can result in interactions or double-doses.
Some community pharmacists were concerned they could not contact the patient’s
specialists directly to discuss medicine changes made by GPs.
Most hospitals do not send the patient’s revised list of medicines to the community
pharmacist. Even those hospitals that do so may not include the medicines list
generated at admission.
★★★ 61 SUGGESTION FOR HOSPITALS, SHPA, PGA AND PSA—The discharge letter (or
those parts concerned with medicine) should be made available to the
patient’s community pharmacist.
quality use of cardiovascular medicines in cardiovascular health / 39
fol low-up
There is strong evidence that follow-up contact with patients is important to recovery.
There was also widespread concern among participants that this was not happening
widely or effectively.
A recent Australian study reported that “[heart failure] programs that incorporate
follow-up by a specialised multidisciplinary team (either in clinic or non-clinic setting)
reduce mortality, heart failure re-hospitalisations and all cause hospitalisations”43.
However, such programs are currently accessible to less than ten per cent of
Australians. A South Australian study of a nurse-led home based intervention for
patients with atrial fibrillation reported fewer readmissions to hospital, fewer days stay
in hospital and fewer fatal events relative to patients receiving the usual post-discharge
care44. Another program involving hospital pharmacists reporting to cardiologists and
community pharmacists has also favourable outcomes45.
While home visits appear to be regarded as the ideal follow-up process, other methods
may also produce good health outcomes. A recent US study of patients who recently
had a defibrillator implanted found that an eight-week education program delivered by
telephone by cardiac nurses significantly lowered anxiety and patient concerns, and
increased their knowledge46. These results were sustained twelve months later47.
For QUM, there is some evidence that medicine reviews shortly after discharge have a
positive impact on patient adherence. However, there is concern that HMRs are not
being well integrated into discharge planning. Currently, only a few hospital
pharmacists are qualified to conduct HMRs—most are done by community
pharmacists, which may also create problems for transitional care.
63 SUGGESTION FOR THE PSA, PHARMACY GUILD AND SOCIETY OF HOSPITAL ★★★
PHARMACISTS—look at ways of making HMRs more accessible and effective
for patients immediately after hospital discharge.
40 / quality use of cardiovascular medicines in cardiovascular health
2. CO O R DI N A T I N G R E H A B I LI T A T I O N S E R V I CE S
As well as taking medicines, there is a range of services to help patients recover from
a heart event or stroke—including rehabilitation, physiotherapy, gymnasiums, and
community health centres. People told us that these were often poorly coordinated,
and many were hard for both consumers and medical professionals to
locate—particularly in regional and remote areas. (None of the people we interviewed
appeared to be aware of the Heart Foundation’s Directory of Australian cardiac
rehabilitation programs.)
★★★★ 64 SUGGESTION FOR GOVERNMENT AND REHABILITATION SERVICES—develop and
implement psychological support programs for consumers, especially post-
discharge and post-rehabilitation.
3. I N T E G R A T I O N O F G P S A N D S P E C I A LI S T S
A concern for general practitioners was getting good contact with the patient’s
specialists. Many GPs want their support and advice on details of their patients’ cases.
Problems that many GPs experience include difficulty making contact, limited time to
discuss issues and receive advice, and problems transferring information.
quality use of cardiovascular medicines in cardiovascular health / 41
GPs also value specialists as a source of advice on new medical practices, medicines,
tests and clinical procedures. Specialists present an opportunity for informal education.
Studies show that specialists have a major impact on general practitioners’ prescribing
habits51, and are therefore crucial in achieving QUM.
4. E DU CA T I N G CO N S U M E R S A N D CA R E R S
There is broad agreement that educating consumers about their condition and its
treatment is central to effective treatment, adherence and avoiding re-admission. One
of the greatest barriers to education is that, after an event, many people want to “put it
all behind them”. They do not attend rehabilitation, or visit a GP, or make contact with
a support group.
Participants stressed that carers need support, as well as consumers. Carers need to
hear what they can expect for themselves while caring for the patient, and what
support is available to them. Carers need to be made aware of their own need for
psychological, emotional, social and physical support—and that they are particularly at
risk of depression, fatigue and stress after the patient returns home. During
rehabilitation, while patients usually receive counselling and psychological help, carers
often go unsupported. We were told that many people eligible for help in their local
communities do not get it—up to fifty per cent of people in some States.
Many people we interviewed emphasised the need for carers to be given information on
the patient’s treatment, as well as the patient themselves. This is especially true in
older couples, where one person will often take responsibility for the care of their
spouse. Doctors and support groups said that one partner frequently answers
questions on behalf of other or looks after their medicine. While giving information to
carers is important in all three phases of treatment, it is particularly relevant at
discharge, when the patient may be frail and in pain or discomfort—and hence less
likely to remember information. Like consumers, carers need to ask questions and be
an active partner in treatment.
5. S U P P O R T G R O U P S
There is some evidence that membership of a support group helps many patients
recover and adhere to their treatments. Support groups can provide advice, social
support and help patients develop skills to manage their treatment. However, research
42 / quality use of cardiovascular medicines in cardiovascular health
criticises GPs for under-referring patients to support groups29, and we were also told
that patients are often not referred during rehabilitation.
★★★ 70 SUPPORT GROUPS—build better links with prevention programs and
rehabilitation programs.
Support groups tend not to deal with the most vulnerable patients—the frail,
immobile, socially-isolated, or those unable to travel. These people are typically dealt
with by nurses—if at all.
supporting environment
E Q U I T Y A N D A CCE S S
An issue of great concern to many we interviewed was improving equity and access to
cardiovascular treatments and medicines in Australia.
As noted in the Background, cardiovascular diseases and deaths are not spread evenly
in the Australian community. They are primarily concentrated in older populations.
People in lower socio-economic groups are more likely to die of cardiovascular diseases
than people in higher, less-disadvantaged groups. People in regional and remote areas
are more likely to have a cardiovascular disease and to die of it than Australians living
in metropolitan areas.
Throughout our interviews, people stressed that many in the Australian community
lacked the support needed to achieve good cardiovascular health. In particular,
participants were critical of the current health and funding systems, which were—in
the words of one participant—“designed for the middle class by the middle class”.
Australians that fell outside this group had trouble accessing the system. They include:
• those on low incomes
• those aged over 65
• indigenous Australians
• people from non-English-speaking backgrounds
• people with limited literacy
• people in regional and remote areas
• the mentally ill.
Despite concern for these issues of equity and access, participants did not make
concrete suggestions about how these issues might be addressed.
LI N K S B E T W E E N S E CT O R S
Throughout the consultation and workshop, participants stressed the importance of
good partnerships between different stakeholders. It is also a major plank of the
National Medicines Policy. Many participants expressed frustration that some groups
in the Medicines Community were unwilling to partner, or else value their
independence above partnership.
Reasons put by doctors for not organising or participating in case conferences included:
• the burden of administration involved
• poor understanding of the MBS Item and claiming procedures
• GPs undervaluing their role
• difficulty fitting conferences within the unpredictability of general practice
• difficulty in travelling
• not knowing that teleconferencing can be claimed under the MBS54.
quality use of cardiovascular medicines in cardiovascular health / 45
350,000
300,000
250,000
claims for
multidisciplinary care plans
200,000
150,000
100,000
claims for
50,000
case conferences
0
1999 2000 2001 2002 2003 2004 YTD 2005
In 2005, the claims processes were simplified and new Medicare Items released.
However, there remain concerns among those we consulted that many general
practitioners do not know about these new items. Encouraging specialists to organise
case conferences may help, as they have more administrative resources than GPs55.
There was some concern that groups were reinventing the wheel, or preferring to stand
alone for the sake of their ‘brand’ or ‘identity’. The result was that consumers received,
for example, conflicting advice on diet, exercise and medicines.
★★★ 78 SUGGESTION FOR THE HEART FOUNDATION—Develop a high-level public
collaboration with other major chronic disease groups (stroke, diabetes,
asthma, arthritis, kidney, cancer, mental illness, musculoskeletal
conditions) to:
(1) form—with the Chronic Illness Alliance—a powerful lobbying group
(2) ensure better coordination and consistency across chronic disease
areas, particularly consistency of health messages.
A particular criticism from several participants was the lack of links between the Heart
Foundation and Heart Support Australia, as the chief cardiovascular support group.
★★★ 81 SUGGESTION FOR THE HEART FOUNDATION—build links with support groups.
In particular, rebuild the relationship with Heart Support Australia.
It is widely believed that the NPS will not partner with pharmaceutical companies or
some consumer groups that receive support from manufacturers. Non-industry
participants appeared unaware that there has been an NPS–industry working group for
the past three years.
quality use of cardiovascular medicines in cardiovascular health / 47
82 SUGGESTION FOR THE INDUSTRY AND NPS—Build and promote NPS-industry ★★★
partnership.
G E N E R A L P R A CT I C E A N D P R A CT I CE N U R S E S
Many of the participants in this project recognised that the chief burden for detecting
cardiovascular diseases, initiating prevention, and helping consumers adhere to their
treatments falls on general practice. And they also recognised that general practice is
already under tremendous pressure, which limits Australia’s ability to assess large
numbers of people and to provide effective interventions to those that need them.
Issues that participants said need to be resolved include:
• Medicare Items for managing chronic diseases (and promotion of existing MBS
Items)
• reduction of administrative load on general practices (currently being pursued
through the Red Tape review)
• lack of general practitioners and supporting health professionals—particularly in
regional and remote areas
• long-term declines in bulk-billing
• poor links with peers and with specialist doctors
• limited use of IT, and poor integration of software packages.
The chief suggestion made to help general practice was to encourage the use of practice
nurses in order to reduce the burden of work that currently falls on doctors. In 2004,
only 40 per cent of Australian practices had practice nurses56. A recent review found
that there was little exploration or data on the potential role for practice nurses, but
did point to some recurring themes:
• there is considerable variation between practices in the roles of practice nurses
• practice nurses can potentially facilitate multidisciplinary interventions for
delivering secondary prevention strategies
• practice nurses are viewed favourably by consumers, although there is some
confusion about their role.57
Some other suggestions for helping general practice, mentioned in the research and
professional literature, include:
• reducing the external administrative burden on general practices
• encouraging general practices to take on practice managers and staff to manage
administration
• helping doctors shift from an acute-care model of health to a chronic-disease-
lifestyle management model of well-being
• encouraging doctors to seek professional support from networks outside their
practices—for instance, through Colleges, Divisions, and specialists
• helping doctors manage the balance between running a medical practice and
running a business.
P O L I CY A N D I M P L E M E N T A T I O N
There were relatively few places where participants felt that basic policy was
lacking—except at the highest level, where some stakeholders want an integrated
National Health Policy and integration of policy across government portfolios with
impacts on health (such as employment, workplaces, family and housing). Some people
stressed the need for a coordinated health policy that would draw together:
• health assessment and monitoring
• prevention
• nutrition and lifestyle
• treatments, health equipment and medicines
• professional standards and training
• resources and health facilities
• research
• public health education.
One of the fundamental barriers seen by many to improving health care in Australia is
the split of responsibilities, policy and funding between the Commonwealth and State
governments. Apart from political disputes over responsibility (which can leave
programs unfunded or under-funded), it creates many opportunities for cost-shifting
that is not in the interests of consumers or their health.
★★★★ 85 SUGGESTION FOR DOHA AND STATE DEPARTMENTS OF HEALTH—develop a
whole-of-life health policy to integrate currently fragmented health
policies.
First, many are fragmented. At the large scale, there is universal agreement of ‘policy
silos’, particularly within DoHA. Policies on medicine, exercise, healthy eating, chronic
disease management, professional development and administration are all largely
uncoordinated. Then there is fragmentation between different parts of medicine policy.
An example noted by several participants is in the discrepancies between Therapeutic
Guidelines, cardiovascular risk assessment tool and the PBS restrictions. They felt this
was a particular concern because, as we noted earlier, some doctors use the PBS
Schedule as a guide to clinical decision-making, and so inconsistencies in policy lead
directly to poor prescribing practices. Some stakeholders also felt that the PBAC itself
was not employing QUM principles in its decisions.
89 SUGGESTION FOR PBAC—better illustrate and explain use of QUM principles ★★★
in PBAC determinations.
Second, many existing policies are incomplete. For example, a point made several times
was that many QUM policies do not include goals or outcome measures, ignore
economic issues, or are unsupported by funding. (In part, this is because economic data
and modelling for many diseases and medicine uses does not exist.)
The third and largest criticism is that QUM policies have not been implemented, or are
not in a state that can be implemented. There appears to be a belief on the part of
policy-makers that developing and publishing a policy framework is sufficient to
achieve QUM. What is omitted in this belief is:
• development of practical methods—so people can act on the principles
• training and education for those that have to act on policy
• development of supporting information, educational materials, and administrative
systems
• provision of funds and resources
• promotion of new methods required to achieve policy objectives
• administrative procedures to underpin policy.
50 / quality use of cardiovascular medicines in cardiovascular health
An example of the lag between the development of QUM principles and application is
in APAC’s Guidelines for Medication Management in Residential Aged Care. Although
released in 1994, it was not until 2005 that the Victorian Government began to
develop training and support materials to help aged care facilities implement the
policy. In 2006, the Commonwealth Government began work on a Common
Medication Chart—the central tool in managing medicines in aged care facilities.
Another example of poor implementation of QUM policy is the APAC Guidelines to
achieve the continuum of quality use of medicines between hospital and community. While
the guidelines were first released in 1998, studies in 2001 and 2002 reported very poor
application of the principles in practice41,42.
★★★★★ 93 SUGGESTION FOR THE SAFETY AND QUALITY COMMISSION, HEALTH
ADMINISTRATORS AND HEALTH CARE ORGANISATIONS—develop materials,
training and incentives to implement the APAC Continuity of Medication
Management guidelines.
The overwhelming need felt by participants was for governments to fund the
implementation of policies and programs—not further trials, or pilots, or further
research, or to develop ‘innovative’ methods or approaches. There is considerable
frustration that many practical QUM solutions have been developed and trialled, but
they have not been adopted. For example, on the topic of discharge planning
—regarded by participants as an area for urgent action—the QUM Map alone lists 25
projects. Other areas where participants felt State and Commonwealth Government
needed to roll out existing programs were:
• practice nurses
• electronic medical records
• Home Medication Reviews
• NatRUM.
I T , CO N N E CT I V I T Y A N D DA T A E X CH A N G E
There appears to be overwhelming support for e-health records, whether as a portable
medical record or in a centrally-maintained database. It is believed that they will greatly
reduce error rates, reduce uncertainty when transferring patients between health care
settings, reduce duplication of effort, allow tracking of medicine use—and ultimately
improve health outcomes.
★★★★★ 95 SUGGESTION FOR DOHA AND MEDICARE AUSTRALIA—develop and implement
electronic health records for all Australians.
quality use of cardiovascular medicines in cardiovascular health / 51
97 Develop and roll out infrastructure, software and training necessary to ★★★★★
support e-health records and connectivity between health care providers.
The issue of privacy continues to be raised, but the MediConnect trials reveal
acceptance from participating consumers and carers58. Only two groups of people
appear particularly concerned about privacy: those connected with mental illness or
and those concerned about sex and sexuality (including unwanted pregnancies,
abortions, sexually transmitted diseases, and homosexuality). Otherwise, there have
been protocols developed to protect the privacy of e-health records59.
Medical professionals still appear uncertain about what medical information they may
disclose—whether electronically or otherwise. Some people believe this leads to over-
protectiveness of information, to the detriment of consumers and continuity of care.
Electronic systems are particularly important for managing long-term diseases and
patients with a number of co-morbidities. While paper-based systems can support
acute care, more complex treatment requires collaboration between many medical
specialities and health settings over many years—and this requires interconnected
information systems.
Also, the links between electronic and paper-based information systems are often not
optimal, leading to incomplete records in both.
T R A I N I N G , E DU CA T I O N A N D I N FO R M A T I O N
The largest group of suggestions raised in this project concerned education—of both
health professionals and consumers—and the training and information required to
support it. Education can be loosely divided into self-directed learning (which relies
heavily on text, printed materials and websites) and inter-personal learning (where
people interact, such as in counselling, informal peer education, professional
development and training courses). Key areas of cardiovascular health where people
wanted education in QUM were for:
• young people
• workplaces
• health care professionals
• consumers and carers (covered in previous sections).
Many participants saw the Heart Foundation as a key body for coordinating
cardiovascular education in Australia.
★★★★ 100 SUGGESTION FOR THE HEART FOUNDATION—Use its established skills to
coordinate broad education of health practitioners and consumers.
One issue raised by a few participants is that most training in cardiovascular medicine
is done in hospitals. However, this environment is quite unlike the community setting
where the long-term management of most chronic diseases takes place. Consequently,
they felt that many medical professionals’ training may not match the circumstances in
which they will work in or that patients live in.
103 SUGGESTION FOR THE DEANS OF MEDICINE, PHARMACY AND NURSING—Include ★★★
training in community settings as part of medical professionals’ education
in chronic disease management.
wor kplace s
An area that attracted only a small amount of attention was the contribution of
workplaces to cardiovascular health and illness, through stress levels, working hours,
food in staff canteens, travel options, and workplace health programs.
104 SUGGESTION FOR THE HEART FOUNDATION—develop and implement (possibly ★★★★
with support groups) a workplace education program around prevention,
risk assessment and healthy living
105 QARG, TGA AND MANUFACTURERS—revise the design of CMI to make it ★★★
shorter and easier for consumers to use, and more attractive for health
professionals to use as a counselling tool.
106 SUGGESTION FOR THE TGA AND PHARMACEUTICAL INDUSTRY—Ensure packet ★★★
information and labels for medicines can be read easily by older consumers
and people with impaired vision.
Most guidelines focus on a single illness or treatment, and do little to help health
professionals manage the common situation where a patient has co-morbidities and
multiple treatments. Most also focus solely or primarily on medical issues, and neglect
the financial, social and lifestyle dimensions of treatment for consumers. (The NHMRC
guides to writing clinical practice guidelines does discuss economics, but their advice
does not seem to be reflected in the actual materials produced.)
★★★★ 111 SUGGESTION FOR THE HEART FOUNDATION—integrate clinical practice
guidelines for cardiovascular treatments with broader chronic disease
management.
Of concern are reports that, although there are now a number of guidelines on
producing clinical practice guidelines, most materials actually produced do not meet
basic quality standards60.
As noted earlier, there is evidence that many general practitioners in particular over-
estimate absolute risk, and cannot tell the difference between relative and absolute
risk. Presumably similar problems are to be found amongst other health care
professionals. Several participants commented decisions about cardiovascular health
need to be made on the basis of absolute risk, and hence absolute risk needs to be used
consistently in materials on cardiovascular health (and presumably other diseases too).
Participants wanted to make existing materials more accessible, before more resources
are devoted to producing new materials.
★★★★★ 113 Develop and maintain a central repository or database or portal of:
• educational materials
• clinical evidence
quality use of cardiovascular medicines in cardiovascular health / 55
114 SUGGESTION FOR THE ROUNDTABLE—to help health professionals, researchers ★★★★
and funders avoid ‘re-inventing the wheel’, develop and make public an
inventory of cardiovascular programs already in place for:
• exercise
• healthy eating
• quitting smoking
• cardiovascular medicine use
• school, workplace and community programs
• peer education programs
• professional development courses.
While DoHA’s Health Insite was intended to be the online gateway to quality-assured
medical information, many of those interviewed felt that:
• it is not widely known or used
• its coverage is incomplete
• it is difficult to search, and
• the information it contains is fragmented and difficult for people to synthesise.
The Clinical Information Access Program (CIAP) includes key Australian textbooks,
research and databases—including the Australian Medicines Handbook—but it is not
publicly accessible or available outside NSW and the ACT.
Several participants felt that governments and advisory bodies are over-reliant on
written information. They ignored the power of word-of-mouth, discussion groups and
telephone-based systems.
A comment made about the Heart Foundation in particular was that, while it is strong
in producing materials, it is weak at disseminating them or getting them adopted. In
hospitals, for example, participants felt that materials were not being distributed by
cardiologists or nursing staff, and patients were not being made aware of the Heart
Foundation materials that are available.
115 SUGGESTION FOR THE HEART FOUNDATION—Review and improve processes ★★★★
for disseminating Heart Foundation information materials in hospitals,
and getting them used by consumers and carers.
116 SUGGESTION FOR THE HEART FOUNDATION—Review and improve processes ★★★★
for informing GPs and specialists of Heart Foundation materials.
used. Some of those we consulted felt that producers of documents regarded their task
as complete once materials had been printed—neglecting distribution, promotion,
engagement of users, and updating of materials.
dev elopin g effe ctive inform ation and ed ucatio nal ma terial s
Some comments about problems with existing education and information—including
materials produced by the Heart Foundation—can be explained by a development
process that focuses primarily on facts and evidence, and that overlooks:
• who will use the information and the circumstances they use it in
• the skills of these people in these situations
• how these people will obtain the information
• what these people need to be able to do with information—that is, what practical
action they need to be able to take with it.
FU R T H E R R E S E A R C H , E V A LU A T I O N A N D M O DE LL I N G
As we noted earlier, the priority for most people consulted was to get policy and
research implemented. A corollary is that many saw little need for further research,
stakeholder workshops or modelling. A great deal of information has already been
generated; people believe that it needs to be better used.
The few outstanding needs for research and modelling are concerned with:
• the evaluation of communication and health promotion
• economic modelling—in particular, to help argue for equity and access
• clinical trials into complementary medicines to establish a reliable evidence base
• realistic clinical trials of medicines that reflect real life use, not mono-therapies
• better tracking of existing medicine use, and connecting it with health outcomes.
119 SUGGESTION FOR THE NATIONAL MEDICINES POLICY—Illustrate how QUM ★★★★
leads to better health outcomes and is cost-effective.
120 SUGGESTION FOR THE INDUSTRY—Design clinical trials to reflect real use of ★★★
medicines.
Consequently, data available to researchers and groups such as DUSC (Drug Utilisation
SubCommittee) is incomplete. While DUSC and others conduct supplementary surveys,
this is costly and the data is intermittent. The current monitoring system has difficulty
tracking the effectiveness of treatments or checking interactions between medicines.
Capturing more complete data—at least on medicines sold by pharmacists —would be
easy using existing pharmacy software, but would need legislative changes to gather.
quality use of cardiovascular medicines in cardiovascular health / 59
missing in action
The bulk of material in this report was based on direct input from stakeholders and
existing research literature. While this produced a wealth of detail, there are noticeable
gaps in it—and in QUM generally. This final section sketches out groups that have a
major role to play in QUM for cardiovascular health, but attracted little attention.
H O S P I T A L A DM I N I S T R A T O R S
In 2000–01, 46 per cent of all health service expenditure for cardiovascular diseases
was for hospital care ($2,533 million)—easily exceeding the combined total of out-of-
hospital medical services (14% or $782 million), aged care facilities (10% or $526
million) and allied health services (1% or $78 million)63.
Hospital administrators, whose task is to manage these costs and allocate resources,
have not been drawn into QUM. Without their involvement, change in hospital
practices is unlikely.
P R I V A T E H E A LT H I N S U R E R S
In 2003–04, private health insurers paid benefits of $7.290 billion for Australian health
expenses64—(although part of this is funded by the Australian Government through
the 30% rebate on private health insurance).
Private health insurers were almost entirely invisible in the discussions we held with
consumers—or in our previous QUM research. As they fund such a large part of health
spending, they are in a pre-eminent position to influence the uptake of QUM by
hospital health professionals. Although they directly pay for just over one per cent of
non-PBS listed medicines, they cover nearly two-thirds of all expenditure in private
hospitals. They are in a position to encourage health service providers to adopt
methods that reduce risk to consumers—such as early risk assessment and continuity
of care plans. They also have the potential to develop continuity of funding across
different health settings in order to support continuity of care.
Private health insurers are aware of the growing disease burden posed by chronic
illnesses—particularly cardiovascular disease. In 2003, Australian Unity and HBA
funded The Freemason’s Hospital in Melbourne to trial AUSeMED. This is a 12-month
chronic disease management program for people that have already been admitted to
60 / quality use of cardiovascular medicines in cardiovascular health
hospital with heart disease, congestive heart failure, respiratory disease, diabetes, or
arthritis. The program:
• links GPs, hospitals, allied health professionals and in-home services
• develops care plans in consultation with the patient’s GP
• develops a transferable medicine record for each patient
• has a 24-hour call centre accessible to patients
• has regular telephone calls from nurses to check progress
• shared medicine records.
The program is currently completing a review of its first 1,500 patients. Initial results
show that re-admissions to hospital and length of hospital stay were both significantly
lower than for other patients.
For insurers, who are uncertain about the scale of potential claims for preventative
cardiovascular care and other chronic disease management, a key issue is reinsurance
—that is, their potential to insure themselves against substantial claims. Ensuring
appropriate reinsurance arrangements may require changes to existing health
insurance regulations.
NUR SES
To date, the health professionals that have received the most attention in QUM
programs have been doctors and pharmacists. Some of those we interviewed felt that
nurses have an important role to play in QUM, especially for cardiovascular health, but
many are unaware of basic QUM principles and lack access to key resources—such as
CMI. Areas that people suggested that nurses might play a larger role include:
• screening
• diet and exercise advice
• checking adherence and medicine use
• discharge planning in hospitals
• managing medical records
• providing counselling and information to consumers and families
• interpreting medical directions and advice for consumers and carers.
We were also told that there is no on-going education for nurses to support them in
their care of cardiovascular diseases. Indeed, it was not clear who is responsible for the
ongoing education of nurses. This has implications for engaging nurses in QUM.
S U P P O R T S T A FF I N G E N E R A L P R A CT I CE
People we consulted said almost nothing about either practice managers or
administrative support in general practice. Both can have a major impact on the
quality use of cardiovascular medicines in cardiovascular health / 61
Practice Managers may also have an impact on patient safety. For example, an
Australian incident-monitoring survey in 1998 identified administrative errors as one
of the twelve most frequent factors contributing to medical harm (9 cases per 100
incidents)65. Practice Managers can also help improve coordination amongst medical
professionals and improve management of medical records.
P H A R M A CE U T I CA L I N DU S T R Y
Surprisingly little was said concerning the role of the pharmaceutical industry, and
coverage was noticeably incomplete. Issues that were raised by participants included
the conduct of research, manufacturing processes, price-setting, and the quality of
CMI. All of these have been raised in previous QUM research.
Consumer groups suggested that the industry has non-medical resources that would be
of value for helping them achieve QUM.
✩✩ 126 SUGGESTION FOR MANUFACTURERS—contribute economic modelling
expertise, or support independent economic modelling, to predict
economic effects of a national cardiovascular risk assessment program.
CA R E R S
Carers have proved difficult to draw into QUM. Other stakeholders recognise that they
have a large role to play in helping patients make decisions about medicines and adhere
to treatment. Participants also recognised that carers have needs of their own,
especially to deal with the stress, social isolation, depression and anxiety that often
results from supporting a person who has experienced a stroke or cardiac event.
S U P E R M A R K E T S A N D FO O D R E T A I LE R S
The bulk of food consumed by Australians is bought at supermarkets, and the buying
power of major supermarket chains has a large impact on the Australian food
production and manufacturing industries. With national concerns about obesity,
supermarkets have a major role to play in improving nutrition and healthy eating.
T H E P U B LI C M E DI A
Most comments and suggestions about information made during our discussions
focussed on materials produced by health organisations—whether by government,
consumer groups, manufacturers or NGOs. As noted by several participants, these
groups have much less influence over consumers’ decisions than the mass
media—including newspapers and current affairs programs, or health advice in
magazines. By talking about, for example, new treatments or medical research, the
media implicitly advises people on particular treatments and options. Practising GPs
have often complained that a single television news item can bring many patients to
quality use of cardiovascular medicines in cardiovascular health / 63
their waiting rooms asking for inappropriate medicines (although we cannot find any
hard evidence to confirm this or how widespread this problem is).
127 Engage the media in health education. In particular, make them aware of:
✩✩✩✩✩
• the impact they have on the lives of consumers and health
professionals, and
• their responsibilities.
There was concern amongst a few participants about the potentially misleading ways
that the media discussed cardiovascular health—particularly research results.
128 Educate the media and medical writers about absolute risk, and how to ★★
interpret medical evidence.
notes
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Heart Foundation Offices
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