DAFTAR ISI

Halaman
HALAMAN JUDUL........................................................................................ i
HALAMAN PENGESAHAN ......................................................................... ii
PERNYATAAN KEASLIAN.......................................................................... iii
ABSTRAK........................................................................................................ iv
ABSTRACT..................................................................................................... v
KATA PENGANTAR...................................................................................... vi
DAFTAR ISI ................................................................................................... xi
DAFTAR TABEL............................................................................................ xiii
DAFTAR GAMBAR........................................................................................ xiv
DAFTAR ARTI LAMBANG DAN SINGKATAN......................................... xvi
DAFTAR LAMPIRAN.................................................................................... xviii
BAB I PENDAHULUAN
A. Latar Belakang .............................................................................. 1
B. Rumusan Masalah.......................................................................... 6
C. Tujuan Penelitian .......................................................................... 7
D. Manfaat Penelitian ........................................................................ 7
BAB II TINJAUAN PUSTAKA
A. Tinjauan Umum Variabel.............................................................. 9
1. Diabetes melitus........................................................................ 9
2. Pengaturan kadar glukosa darah oleh insulin........................... 23
3. Insulin-like Growth Factor 1.................................................... 25
4. Buah Pare.................................................................................. 32
5. Streptozotocin........................................................................... 42
6. Polymerase chain reaction (PCR)............................................ 45
B. Kerangka Teori ............................................................................. 48
C. Hipotesis Penelitian....................................................................... 49
D. Kerangka Konsep........................................................................... 49
BAB III METODE PENELITIAN
A. Rancangan Penelitian..................................................................... 50

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 B. Waktu dan Lokasi Penelitian......................................................... 50
C. Populasi dan Sampel Penelitian..................................................... 50
D. Teknik Pengumpulan Data............................................................. 52
E. Definisi Operasional...................................................................... 64
F. Analisis Data.................................................................................. 65
G. Alur Penelitian............................................................................... 68
H. Etika Penelitian.............................................................................. 69
BAB IV HASIL DAN PEMBAHASAN
A. Gambaran Umum Lokasi Penelitian.............................................. 71
B. Hasil penelitian.............................................................................. 73
C. Pembahasan................................................................................... 85
D. Keterbatasan Penelitian.................................................................. 90
BAB V PENUTUP
A. Simpulan........................................................................................ 91
B. Saran.............................................................................................. 91
DAFTAR PUSTAKA....................................................................................... 92
LAMPIRAN.....................................................................................................

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