DAFTAR ISI

Halaman

Halaman Judul ............................................................................................ i

Lembar Pengesahan..................................................................................... ii
Lembar Pernyataan Keaslian....................................................................... iii
Lembar Persetujuan Publikasi...................................................................... iv
Biodata......................................................................................................... v
Kata Pengantar............................................................................................. vi
Daftar Isi...................................................................................................... viii
Daftar Tabel................................................................................................. x
Daftar Gambar.............................................................................................. xii
Daftar Singkatan.......................................................................................... xiii
Abstrak......................................................................................................... xiv

BAB 1 PENDAHULUAN
A. Latar Belakang.......................................................................... 1
B. Rumusan Masalah..................................................................... 7
C. Tujuan Penelitian...................................................................... 8
D. Manfaat Penelitian.................................................................... 8
E. Ruang Lingkup.......................................................................... 9

BAB II TINJAUAN PUSTAKA

A. Pengertian Tuberkulosis (TB) Paru........................................... 11
B. Biomolekuler TB Paru.............................................................. 11
C. Penularan TB............................................................................. 14
D. Patogenesis................................................................................ 17
E. Diagnosis TB ............................................................................ 20
F. Definisi Kasus dan Klasifikasi Pasien TB................................ 28
G. Pengobatan TB.......................................................................... 33
H. Program Penanggulangan TB di Puskesmas............................. 39
I. Faktor Karakteristik Responden ............................................... 40
J. Faktor yang berhubungan dengan Kesembuhan Penderita
TB ...................................................................................... 40
K. Indikator Program TB............................................................... 48
L. Analisis Indikator TB................................................................ 52
M. Kerangka Teori.......................................................................... 55
N. Kerangka Konsep...................................................................... 56
O. Hipotesa..................................................................................... 56

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BAB III METODOLOGI PENELITIAN
A. Jenis Penelitian............................................................................ 58
B. Waktu dan Tempat Penelitian..................................................... 58
C. Rancangan Penelitian.................................................................. 58
D. Subjek Penelitian......................................................................... 59
E. Variabel Penelitian...................................................................... 60
F. Definisi Operasional.................................................................... 61
G. Pengumpulan Data....................................................................... 62
H. Pengolahan Data.......................................................................... 68
I. Analisis Data............................................................................... 69

BAB IV HASIL PENELITIAN & PEMBAHASAN

A. Gambaran Umum........................................................................ 71
B. Hasil Penelitian........................................................................... 73
1. Analisis Univariat Karakteristik Responden........................... 73
2. Analisis Univariat Variabel Penelitian.................................... 76
3. Analisis Bivariat Variabel Penelitian...................................... 79
4. Analisis Multivariat................................................................. 84
C. Pembahasan................................................................................. 90

BAB V KESIMPULAN & SARAN

A. Kesimpulan.................................................................................. 118
B. Saran............................................................................................ 119

DAFTAR PUSTAKA
LAMPIRAN

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 DAFTAR TABEL

Halaman

Tabel 2.1 OAT Lini Pertama..................................................................... 35

Tabel 2.2 OAT Lini Kedua....................................................................... 35
Tabel 3.1 Definisi Operasional.................................................................. 61
Tabel 3.2 Blueprint Skala Perilaku Kepatuhan ........................................ 64
Tabel 3.3 Distribusi nilai validitas dengan Skala Guttman ...................... 66
Tabel 3.4 Distribusi nilai validitas dengan Skala Likert........................... 66
Tabel 3.5 Distribusi nilai reliabilitas dengan Skala Guttman.................... 67
Tabel 3.6 Distribusi nilai reliabilitas dengan Skala Likert........................ 68
Tabel 4.1 Karakteristik responden berdasarkan jenis kelamin.................. 73
Tabel 4.2 Karakteristik responden berdasarkan umur............................... 73
Tabel 4.3 Karakteristik responden berdasarkan pendidikan..................... 74
Tabel 4.4 Karakteristik responden berdasarkan pekerjaan........................ 75
Tabel 4.5 Karakteristik responden berdasarkan penghasilan.................... 75
Tabel 4.6 Distribusi frekuensi kategori kesembuhan pengobatan TB...... 76
Tabel 4.7 Distribusi frekuensi status gizi penderita TB............................ 76
Tabel 4.8 Distribusi frekuensi kepatuhan berobat penderita TB............... 77
Tabel 4.9 Distribusi frekuensi komplikasi penyakit lain........................... 77
Tabel 4.10 Distribusi frekuensi pengetahuan penderita TB........................ 78
Tabel 4.11 Distribusi frekuensi sikap penderita TB.................................... 78
Tabel 4.12 Hubungan status gizi dengan kesembuhan pengobatan TB...... 79
Tabel 4.13 Hubungan kepatuhan berobat dengan kesembuhan
pengobatan TB.......................................................................... 80
Tabel 4.14 Hubungan komplikasi penyakit lain dengan kesembuhan
pengobatan TB.......................................................................... 81
Tabel 4.15 Hubungan pengetahuan penderita dengan kesembuhan
pengobatan TB.......................................................................... 82
Tabel 4.16 Hubungan sikap penderita dengan kesembuhan
pengobatan TB.......................................................................... 83
Tabel 4.17 Hasil analisis bivariat status gizi, kepatuhan berobat,
komplikasi dengan penyakit lain, pengetahuan dan
sikap penderita TB.................................................................... 84
Tabel 4.18 Hasil analisis multivariat status gizi, kepatuhan berobat,
Komplikasi dengan penyakit lain, pengetahuan dan sikap
Penderita TB.............................................................................. 85
Tabel 4.19 Pemodelan multivariat dengan mengeluarkan variable
status gizi .................................................................................. 85
Tabel 4.20 Perubahan OR setelah variable status gizi dukeluarkan ........... 86
Tabel 4.21 Uji interasi antara status gizi dengan komplikasi dengan
penyakit lain ........................................................................... 87

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Tabel 4.22 Uji interasi antara kepatuhan dengan pengetahuan penderita ... 88
Tabel 4.23 Uji interasi antara kepatuhan dengan sikap penderita................ 89
Tabel 4.24 Analisis faktor penderita yang berhubungan dengan
kesembuhan TB ....................................................................... 89

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 DAFTAR GAMBAR

Halaman
Gambar 1. Mycobacterium tuberculosis. Scanning electron
micrograph. Mag 15549X. CDC .......................................... 12
Gambar 2. Perjalanan Alamiah TB pada Manusia................................... 16
Gambar 3. Patogenesis TB Paru............................................................... 19
Gambar 4. Diagnosa Alur TB................................................................... 27
Gambar 5. Four layers of health determinants model.............................. 43
Gambar 6. Skema faktor risiko TB model Ivanovs.................................. 45
Gambar 7. Faktor risiko infeksi Tuberkulosis model Narasimhan........... 46
Gambar 8. Kerangka Teori....................................................................... 55
Gambar 9. Kerangka Konsep.................................................................... 56
Gambar 10. Peta wilayah Kabupaten Lampung Selatan............................ 71

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 DAFTAR SINGKATAN

BTA : Basil Tahan Asam

CDR : Case detection rate
CNR : Case Notification Rate
DNA : Deoxyribonucleic acid
DOTS  : Directly Observed Treatment Shortcourse
HIV : Human Immunodeficiency Virus
MDG’s : Millenium Development Goal’s
MDR : Multi drug resistan
MOTT : Mycobacterium Other Than Tuberculosis
OAT : Obat Anti Tuberkulosis
PDPI : Perhimpunan Dokter Paru Indonesia
PMO : Pengawas Minum Obat
PPOM : Penyakit Paru Obstruktif Menahun
TB : Tuberkulosis
TCM : Tes Cepat Molekuler
UPK : Unit Pelayanan Kesehatan
UPT : Unit Pelaksana Teknis
WHO : World Health Organization

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