NIPER -2010 11 july 2010

1-carbomer composition 25-plasmid of bacteria-characters

2-rifampicin solublity in bbb 26- a lot of cology ques has come about 60 in no.
3-mao of erythromycin drug used in glycemic control in diabetes
4 which drug is safe in renal failure- a pioglitazone
cloxacillin,streptomycin,cephalorin b-
5 defination- antibody titer 27-insulin contraindicated with
6 protein precipitation used for a-propranol b- c- d-
a-for estimation of protein from urine 28-in hypertension which drug give immediate relief?
b-'' '' '' '' '' serum a- nitroprusside b-prazocin
c- ' '' '' '' '' blood 29-interaction ofsildenafil and nitroglycerine
7- listerine(brand name for a mouth wash) manufac by 30 types of bond in antigen and antibody interaction
a johnson and johnson a-hydrophobic b- vander waal c-covalent bond
b procter ang gamble 31-heparin action blocked by—quinidine
7- i-pill is marketed by-------- 32-drugs that stimulate CTZ zone –
8-in india commodity bussiness sontrolled by morphine,
a-SEBI apomorphine,
b-frm serotonin
c- 33-antidote of cyanide
d- 34-which process not blocked by cyanide hmp
9- ist ayush gram located in pathway.krebs cycle, glycolysis
uttrakhand ,himachal pradesh 35-which process ds not occur in mitochondria
10-mao of flouroquinolone kreb cycle
11 teratogenicity of corticosterods ,thalidomide lipid biosynthesis
12-maths question about identification of trapezoid 36-cholestrol on dehydrogenation yields ---
13-freeze thaw test used for suspension 37-wittg reaction
a- for degradation 38-Wolf kishner reaction
b-crystalization of suspension(i think it is right) 39-clemmenson reaction
14.chem const of atopa belladona 40-friedal craft acylation
many ques are frm cognosy abt biological source chem 41-mobile phase used in reverse phase chromatography
constituent..no ques from biosynthesis
14 -how many doublets contains paracetamol? 42-Stomata in senna?
15-mull used in a-ft ir b-raman 43-Borntrager test is used for?
16.mclaffrey ion m/z values 44-FDA approved drug for Osteoporosis in2010?
17homoannolar and heteroannular dienes Ans-DENOSUMAB
18-calculation of lambda max using wood word fisher
rule of uv 45-FDA approved drug for Gout IN 2OO9?
19-carbocation stablity FEBUSTAT
20.bond energies a- C-H >C-C>C-OH >C-CL 46-Chief constituent of Dill?
b-C-CL>C-H >C-C>C-OH 47-Ribosomes are synthesized in?
c- 48-What happens in inetrphase?
d- 49-Cis and trans are ?(Distereomers/Enantiomers)?
21-which is a nucleophile 50-Adrenergic blockers are also called as?
a NH2 b-cooh c - d- Sympatholytics
Parasympathomimeics
22-enzyme used for cutting dna in biotecnology sympathommimetics
23-defination of specific 51-Cipla has recently sold iits i-pill to which company?
24-specific activity of enzyme 52-Nobleprize winner for medicine in 2009?
53-COMFA is used for?
a-3d qsar
b-docking
54-SWs for Docking? 85-the base peak has?
a-gold a-low intensity
b-glide b-highest intensity
c-
d-all of above 86-the effect of conjugation on IR absorbtion?
55-Which detector in HPLC is most temprature sensative? 87-scientist name for discovery of quartlet stereochemistry in
56-Epigenetic DNA? carbon?
57-Scientific name of clove? 88-structure of d-valine
58-NF kappa is used in? 89-essential fatty acids
59-What are Paratopes? 90-epimers definition
60-Acid fast stains which part of mycobacterias? 91-anomers
61-Histones are present? 92-diasteriomers and enantiomers definition
a-Eukaroyotes 93- sn2 reaction
b-Prokaryotes 94-the effect of plant forskolin is due to
c-both Ans stimulation of adenyl cyclase
62-Nilkeni's UIC is now called as? 95-aflatoxin presenting
Pankh a-fungi
AADHAR b-algae
63-Orthostatic hypertension is a side effect of? 96-trypsin obtained from
Methyldopa a-pig stomach
reserpine b-ox stomach
64-Chloramphenicol is used as?
antibiotic 97-for taste masking of bitter orals which of following used
65-indication for reserpine? a-citrus fruits
Ans-hypertension b-liquorice
66-sennosides present in? 98-the sulfasalazine consist of
67-Chief constituent of Dill? A-PAS + SULPHAPYRIDINE
carvone B-PAS +SULPHASALAZINE
68-dsc in anal 99-H.PYROLI cause
69- which of the line abt disintegration test is right? Ans ulcers
A-it is not for delayed release dosage form 100- which of the following is a motile bacteria
b-if in monograph of capsule DT is not mentioned, it is not done a-shegala
c-both are wrong b-lactobacilus
70- for tab below 300 mg weight variation shld be
a-7.5% 101-the capsules are washed with
b-10% a-acetone
c-5% B
71-detector used in hplc? C
73-which of the following is a mucoadhesive? d
74-Cipla has recently sold iits i-pill to which company? 102-recinoleic acid present in
75-the lag phase in growth of bacteria can be prevented by? Ans nutmeg
a-replacing with new media 103-stereoisomerism of cinnamic acid
b-replacing with alive bacteria 104-tocopherol an antioxidant act as a --------
Ans-reducing agent
76-paracetamol most severe sideffect?
Ans-nephrotoxicity 105 general method for sterilization of glass is-
78- water immiscible non polar solvent? a-autoclavin
A-Isopropyl myristitate b-gamma radiation
b-PEG c-dry heat method

79-PEG coating done on lipsome 106-which of the following can’t be autoclaved-

a- to obtain delayed release a-polypropylene
80- in myasthenia gravis the receptor damaged by autoimmunue b-teflon
process are? c-nylon
81- name the propellant 152
82-IND stand for?
83-drug used for schizophrenia? no ques from English and bank