Cxxx-Exxx

ELSD-LT
Evaporative Light Scattering
Detector -Low Temperature
Shimadzu has now completed the family of HPLC detectors
with the introduction of the ELSD-LT. The ELSD-LT is ideally
suited for applications in drug discovery, natural products
development, combinatorial chemistry and proteomics.
Analytes are detected regardless of their chromophoric
properties. Essentially all compounds are detected even if
they do not contain a chromophore or an electroactive
group.The low temperature integrated design prevents the
decomposition of thermally labile compounds resulting in
increased assay sensitivity. The ELSD-LT is a universal mass
sensitive detector with the following key benefits:

Mobile Phase

Gas

Nebulizer, Evaporation tube

■ Low temperature operation

The ELSD-LT optimizes sensitivity of thermally labile compounds
by low temperature evaporation of the mobile phase using a three
step process. This system can evaporate a mobile phase
consisting of 100% H2O at 320C. Other systems require an
special accessory to evaporate the mobile phase. ELSD-LT
has an integrated design for optimizing sensitivity,
performance and ease of operation.
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■ New Cell Design Reduces Band Broadening

The innovative cell design minimizes band broadening providing a
similar bandwidth as UV, UV-VIS detectors.
ELSD-LT provides Narrow Peak width, even at high flow rates!

■ Excellent Performance using Gradients

The ELSD-LT provides excellent resolution of analytes since
gradients can be used to optimize separations. The mobile phase
is removed from the eluent even at high flow rates such as
4ml/min. with uncompromised resolution.

■ Quantitation of all Analytes in a Sample

Essentially all compounds in a sample provides a signal allowing
accurate quantitaion. The detector response is related to the
mass of the compound not UV absorbance making this detector
extremely useful for the combinatorial chemist. The ELSD-LT is
a universal detector.

ELSD-LT - Shimadzu’s Universal Detector

 ELSD-LT - the Universal Detector- a Solution for Science

The ELSD-LT detector will be available in three different varieties.

The standard model which
features a new nebulizer and evaporation tube to produce
formation of a more uniform droplet
size. These new features maximize more efficient and rapid
evaporation of the mobile phase.

Specifications of ELSD-LT (Cat. No. 228-45021-xx -32: 115V, -38: 240V CE)
Light source Tungsten-halogen lamp
Detection Photomultiplier tube
Temperature setting range Room temperature – 80°C
Nebulizer gas Nitrogen or air
Gas pressure 450kPa
Gas flow rate 3.0 L/min max.
Operating flow rate 0.1 – 5.0 mL/min
Output Analog 0 – 10mV, 0 – 1V
Input/output terminals RS-232C
Operating temperature range 5°C – 40°C
Operating humidity range ~80%, (31°C)
Power supply 115 V or 240 V, 150 VA, 50/60 Hz
External dimensions W360×D500×H504（ mm）
Weight 20 kg

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