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Urol Clin N Am 29 (2002) 429–441

Reconstruction of posterior urethral disruption


George D. Webster, MB, FRCS*,
Michael L. Guralnick, MD, FRCSC1
Division of Urology, Box 3146, Duke University Medical Center, Durham, NC 27710, USA

Traumatic disruption of the prostatomembra- cases, however, complete transection of the ure-
nous urethra occurs in approximately 10% of thra occurs and the degree of initial urethral
men with pelvic fracture, blunt trauma from separation will be dictated by the size of the pelvic
motor vehicle accidents, or occupational injuries hematoma and intactness of the fascial attach-
accounting for at least 90% of cases [1–3]. In this ments between the prostate and pelvic floor and
review the authors address the etiologic and ana- pelvis (Fig. 3). The resulting ‘‘stricture’’ is techni-
tomic factors of posterior urethral disruption, con- cally not a true stricture but rather a distraction
troversies regarding the initial management of such defect as there is no urethral lumen per se between
injuries, options for delayed surgical repair of ure- the two urethral ends [6,7].
thral distraction defects, complications of the inju- In the majority of distraction defects the
ries, and their management. separation is minor, and with the passage of time
the bladder and prostate will descend as the hema-
Extent of urethral injury toma is resorbed, resulting in a shorter urethral
defect. The most disastrous scenario is that which
Generally, the magnitude of the injury will follows massive trauma with resultant wide sepa-
determine the extent of the initial vesicourethral ration of the urethral ends and injury to other local
dislocation and hence the length of the ultimate structures including the bladder and rectum. Con-
defect. The urethra is most often injured in frac- comitant bladder injury has been reported to occur
tures that disrupt the anterior pelvic ring but can in 18% of cases of posterior urethral disruption,
also be injured with simple symphyseal diastasis and associated rectal injury, although less com-
[4,5]. In the least traumatic scenario the membra- mon, has historically carried extremely high mor-
nous urethra is elongated because of tearing of bidity and mortality [8,9].
the vesicoprostatic attachments to the pelvic floor,
allowing the bladder and prostate to ascend on an
Classification of posterior urethral injuries
enlarging pelvic hematoma (Fig. 1). This can result
in intramural fibrosis of the membranous urethra Various classifications for posterior urethral
with functional impairment of the distal intrinsic injury have been developed. The most popular is
sphincter mechanism, but generally a stricture that of Colapinto and McCallum [10], which clas-
does not develop. With more severe trauma, actual sifies injuries based on the appearance of the retro-
tearing of the urethra can occur. In approximately grade urethrogram (Table 1). Goldman et al [11]
one third of cases a partial tear occurs with urethral modified this by including a concomitant bladder
continuity maintained (Fig. 2). In the majority of neck injury as Type IV.
Type II injuries are considered to be so-called
‘‘classic’’ posterior urethral injuries, but a type
* Corresponding author.
1
Current address: Division of Urology, Medical
III injury is more common [10,12]. It can be diffi-
College of Wisconsin, 9200 W. Wisconsin Avenue, cult to identify the exact location of extravasa-
Milwaukee, WI 53226. tion on retrograde urethrogram (RUG), which
Dr. Guralnick is supported by a grant from the therefore places limits on the usefulness of such a
R. Samuel McLaughlin Foundation, Toronto, Canada. classification scheme [13].
0094-0143/02/$ - see front matter  2002, Elsevier Science (USA). All rights reserved.
PII: S 0 0 9 4 - 0 1 4 3 ( 0 2 ) 0 0 0 4 2 - 3
430 G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441

Fig. 3. Retrograde urethrogram of complete urethral


disruption. There is extravasation into the perineum
with a lack of urethral continuity and no filling of the
Fig. 1. Pelvic fracture with elongation injury to the bladder. (Borrowed from Urologic Clinics 1989 16(2):
urethra. Vesicoprostatic attachments to the pelvis are 283. Carl M. Sandler, MD and Joseph N. Corriere, Jr,
disrupted and the bladder has floated cephalad on a large MD. Urethrography in the Diagnosis of Acute Urethral
hematoma, stretching the membranous urethra. How- Injuries.)
ever, no disruption resulted. (From Webster GD. Manage-
ment of complex posterior urethral strictures. Probl Urol
1987;1:304.)
membranous urethra before reaching their even-
tual position ventral to the corporal bodies. Their
route is important in preventing further erectile
Anatomy compromise.
Penile vascular supply is discussed elsewhere Erectile dysfunction (ED) is common immedi-
in this issue and will not be addressed here. The ately following pelvic fracture injury. Many pa-
cavernous (erectile) nerves originate from the tients ultimately do recover their erections, but it
sacral plexus (S2,3,4) and course in neurovascular
bundles along the posterolateral aspect of the pros-
tatic urethra, taking a more lateral position at the
Table 1 Classification of posterior
urethral injuries
Type I: Membranous urethra stretched
but intact; no extravasation
Type II: Partial/complete rupture of
membranous urethra above urogenital
diaphragm; extravasation into pelvis.
Type III: Partial/complete rupture of
membranous urethra extending into
proximal bulbar urethra; extravasation
into perineum
Type IV: Concomitant injury to bladder
neck

(From Colapinto V, McCallum RM. Injury


to the male posterior urethra in fractured pel-
vis: a new classification. J Urol 1997;118:575
Fig. 2. Partial tear of the urethra following pelvic as modified by Goldman SM, Sandler CM,
fracture. Continuity of the urethra is maintained by Corriere JN, McGuire EJ. Blunt urethral
extravasation, as seen on this retrograde urethrogram. trauma: a unified, anatomical mechanical
(From Webster GD. Management of complex posterior classification. J Urol 1997;157:85.)
urethral strictures. Probl Urol 1987;1:304.)
G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441 431

can sometimes take up to 2 years [14]. Permanent If it is felt that the patient urgently requires blad-
ED following a pelvic fracture injury is usually sec- der drainage but is too unstable to perform a
ondary to neurogenic [15] or vasculogenic [16] RUG, the safest thing to do is place a percutane-
insults due to the injury, but this might be com- ous suprapubic tube and evaluate the urethra once
pounded by the surgical procedure itself. the patient is more stable.
Urinary continence in the male results from a
sphincter mechanism located along the entire Management
posterior urethra from the bladder neck to the Historically, posterior urethral injuries were
bulbomembranous junction. It has two compo- managed by early intervention to re-align or repair
nents: a proximal (or bladder neck) sphincter and the urethra and drain the pelvic hematoma. This
a distal sphincter. The proximal sphincter is a approach was associated with an unacceptably
cough (stress) competent mechanism, but opens high rate of impotence and incontinence, so a shift
in association with a detrusor contraction, whether toward a more conservative approach using im-
voluntary or involuntary. The distal sphincter mediate suprapubic catheter drainage followed by
mechanism is confined to the 3 to 5 mm thickness delayed urethroplasty was made [20]. With the re-
of the wall of the posterior urethra from the level cent advances in endoscopic techniques and
of the verumontanum down to the distal part of the realization that, in general, the magnitude
the membranous urethra. This intrinsic mecha- of the injury rather than the initial management
nism comprises slow-twitch striated muscle fibers is responsible for impotence and incontinence,
capable of sustained contraction to maintain con- the approach to managing these injuries is again
tinence. In addition, there is periurethral striated mired in controversy. A rational approach is a
muscle that is related to the posterior surface of compromise in which the timing and type of inter-
the membranous urethra and is capable of inter- vention are dictated by the magnitude of the injury
rupting the voided stream momentarily but incap- and the presence of complicating injuries to adja-
able of maintaining continence in the absence of a cent structures.
functional intrinsic mechanism. For urinary conti-
nence to be maintained, either the bladder neck
sphincter or the distal intrinsic sphincter must be
Indications for acute surgical intervention
intact. Pelvic fracture injuries of the membranous
urethra and their subsequent repair invariably Early surgical intervention is absolutely indi-
destroy the distal intrinsic sphincter mechanism, cated when there is an associated injury to the rec-
making subsequent continence dependent on an tum (generally identified by rectal examination)
intact bladder neck mechanism. because the resulting contamination of the pelvic
hematoma demands urgent management. In such
cases the infected hematoma must be drained, the
Acute management of posterior urethral injuries pelvic floor irrigated, and the urethra realigned over
a fenestrated catheter. A sigmoid colostomy is also
Diagnosis
performed.
Generally the trauma victim with a posterior Concomitant bladder injury occurs in 10% to
urethral injury has suffered multiple injuries, and 20% of patients with urethral disruption [21] and
initial management is aimed at resuscitation and is best diagnosed as extravasation on a cystogram
stabilization. Clinical signs that should raise suspi- or CT cystogram [17,18]. Laparotomy and closure
cion of a posterior urethral injury include blood at of the bladder are necessary, but provided that
the urethral meatus, the inability to void, and the the bladder neck is not torn, there is no reason
presence of a perineal hematoma. If there is any to evacuate the pelvic hematoma, and delayed
suspicion of a posterior urethral injury, a RUG management of the urethral injury might still be
should be performed looking for extravasation of appropriate. Should the bladder neck be involved,
contrast. If no extravasation is seen, a Foley cathe- however, it is most important that it be carefully
ter can be inserted and a cystogram or upper tract reconstructed in the early post-injury period,
study can be performed as indicated. While cur- because after the membranous urethral disruption
rently CT scans are routinely used in the evalua- that predictably destroys the distal sphincter
tion of abdominal and pelvic trauma and might mechanism, continence will require its function.
identify bladder rupture [17,18], a CT is not useful Bladder neck lacerations should be debrided care-
for diagnosing prostatomembranous injuries [19]. fully and the bladder neck reconstituted around
432 G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441

the stenting catheter in hope that this procedure essentially two schools of thought: those advocat-
will preserve sphincter function. The timing of this ing immediate or early intervention to repair or
repair should be based on the stability of the pa- realign the urethra versus those advocating a more
tient; it might be prudent to initially place a supra- conservative approach with initial suprapubic
pubic tube then perform the surgery in the next few catheter drainage followed by delayed repair of
days. the resultant stricture/PFUDD.
The final indication for early surgical interven- It is difficult to compare studies examining the
tion is wide separation of the urethral ends asso- various management strategies because of limited
ciated with massive pelvic hematoma. It is futile numbers of patients, limited follow-up, differing
to anticipate that hematoma absorption will be definitions of success and failure, and significant
complete or that after absorption the prostate will selection bias. Only in a randomized study could
descend to an anatomic position, and it is likely a definitive answer be given, but in the current
that a very long stricture will result (Fig. 4). To medico–legal climate this is unlikely to be possible.
avert a later heroic urethroplasty, early hematoma Nevertheless, each type of management with res-
evacuation and re-approximation of the severed pect to stricture recurrence and complications such
urethral ends is appropriate to minimize the length as incontinence, erectile dysfunction, and bleeding
of the subsequent stricture. As noted above, how- will be addressed.
ever, it might be advantageous to initially place a
suprapubic tube and allow the patient to stabilize
Primary suture repair
then perform hematoma evacuation and urethral
realignment/repair [22]. In this way the retropubic Primary suture repair involves retropubic hema-
hematoma will have had time to stabilize but not toma evacuation and urethral debridement fol-
yet fibrose. lowed by sutured repair over a stenting catheter.
This technique is primarily of historical interest
now as it has become clear that it is associated with
Management options when indications
a high incidence of incontinence and erectile dys-
for immediate repair are not present
function [23].
It is in this group of patients that the most con-
troversy regarding management exists. There are Primary urethral realignment
Primary re-alignment procedures involve the
open placement of a catheter across the urethral
defect to serve as a stent without formal suture re-
pair. They generally involve using interlocking
sounds or a railroading technique, whereby ante-
grade and retrograde catheters are connected as
they exit into the retropubic space to bridge the
defect and subsequently place a catheter [24,25].
The potential advantage of this type of manage-
ment is a reduction in the incidence and severity
of stricturing compared to an initial suprapubic
(SP) tube and delayed management. Nevertheless,
re-stricturing is noted in at least 50% of patients
[23] and has been reported in up to 100% of pa-
tients [26,27]. This high rate might necessitate
additional procedures (endoscopic or open) or
intermittent catheterization [25]. While some argue
that the need for periodic ‘‘office’’ urethral dila-
Fig. 4. A combined urethrogram and cystogram in a
tions is a minor inconvenience [24], the authors
patient with severe urethral separation following pelvic
fracture. Early hematoma evacuation and re-approx- and others believe that the need for any subse-
imation by re-alignment over a stenting catheter would quent instrumentation constitutes a treatment fail-
be appropriate in such a case. (From Webster GD. ure [28]. Complications such as incontinence and
Management of complex posterior urethral strictures. erectile dysfunction appear to be low in expert
Probl Urol 1987;1:306.) hands [24] and were reported to occur in 5% and
G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441 433

36%, respectively, in Koraitim’s review of 326 cases 6 weeks and is removed after confirmation of a
of primary realignment reported in the literature lack of extravasation. The suprapubic catheter is
[23]. The risk of significant bleeding exists, particu- removed when adequate voiding is achieved.
larly if the tamponade effect of the retropubic Proponents of this treatment argue that it is a
hematoma is lost following drainage, and this can straightforward procedure that most urologists
turn a cautious procedure into a frantic attempt at are capable of performing and it permits early re-
hemostasis, which will increase the risk of the alignment of the urethra, which might reduce the
above-mentioned complications. Thus the proce- incidence and severity of stricturing and avoid
dure is best left in the hands of experienced sur- the morbidity of open re-alignment or delayed
geons who are well versed in the techniques of urethroplasty [31,32]. Re-stricturing has been re-
pelvic and urethral surgery. ported in 20% to 100% of patients undergoing the
procedure, however [31–37]. This high rate necessi-
Initial suprapubic catheterization tates repeat procedures (usually endoscopic) and,
and delayed repair often, intermittent self-catheterization to maintain
urethral patency, although this might be accepta-
The current vogue of an initial SP tube fol-
ble to patients [31]. The technique does not seem
lowed by delayed management of the resultant
to increase the risk of incontinence or ED, which
stricture arose from the observation that patients
are related to the severity of the injury [31–37].
managed in such a fashion had a lower incidence
There are few series in the literature, however, and
of impotence and incontinence than those mana-
all are plagued by small numbers of cases and
ged by immediate repair [20,23]. While the major-
short follow-up periods.
ity of patients will develop a resultant stricture,
It is apparent that each type of management
there are some who heal without stricture forma-
can be successful in select patients when performed
tion, particularly if there was only partial urethral
by experienced surgeons. While it is agreed that the
disruption [29]. Furthermore, the strictures that do
majority of impotence and incontinence is related
result are usually short (\2 cm) and amenable to a
to the magnitude of the initial injury, there is no
one-stage perineal anastomotic urethroplasty, as
question that their incidence might be worsened
described later [1,30]. In two reviews of the litera-
by injudicious use of aggressive interventions by
ture on this type of management incontinence was
inexperienced surgeons. Therefore, while no defi-
noted in \5% of patients and impotence in \20%
nitive conclusions can be made regarding the most
of patients [20,23]. Since posterior urethral injury
appropriate management technique, it is possible
is not common, most centers will not have a large
to make several recommendations.
experience in managing these cases; thus manage-
Immediate suture repair with evacuation of the
ment by an initial SP tube and referral for delayed
pelvic hematoma should not be used unless there is
repair will likely be preferable.
a concomitant bladder neck injury that requires
suture repair. Immediate open realignment is best
left to surgeons who have a extensive experience
Early endoscopic re-alignment
with the various techniques, because the potential
Early endoscopic re-alignment is a compromise for disastrous complications (eg, hemorrhage) is
between immediate open re-alignment and initial significant. Early endoscopic realignment follow-
SP tube and delayed management, and it is based ing immediate suprapubic catheter drainage is
on success obtained with delayed endoscopic re- probably more suited to most urologists. A solid
pair (see later sections). Immediate urologic man- understanding of endoscopic anatomy is required,
agement is placement of an SP tube followed by and again it should be anticipated that some type
a delay of a few days to weeks so the associated of stricture will result following the technique that
injuries (eg, orthopedic, abdominal) can be man- will require additional procedures (eg, CIC, dila-
aged and the patient stabilized. This delay also tions, direct vision urethrotome [DVIU]). Extreme
allows for stabilization of the pelvic hematoma. caution is necessary in performing these tech-
The patient is then brought to the operating room niques due to the risk of creating a complex stricture
where, in general, a combined antegrade and retro- by causing anterior urethral scarring, fistula, or
grade endoscopic approach is used to pass a guide rectal injury. The safest management strategy is
wire or ureteral catheter across the urethral defect, simply placing a suprapubic catheter with delayed
and placement of a urethral catheter over the guide management of any subsequent stricture (see later
wire follows. The catheter is left in situ for 4 to sections). Subsequently, referral to a tertiary center
434 G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441

with expertise in urethral reconstruction for logic findings is needed, retrograde and antegrade
delayed stricture management is ideal. rigid or flexible endoscopy can be performed,
which can help in the assessment of bladder neck
integrity and spongiofibrosis. Recently, MRI has
Delayed repair of PFUDD
been proposed as an adjunct for staging PFUDDs
The delayed management of posterior urethral because it can accurately estimate the length of the
distraction defects falls broadly into two cate- defect and differentiate hematoma, fibrosis, and
gories: endoscopic procedures and open surgical pre-existing prostatic enlargement [16].
repairs. Procedure selection will be dictated by
the nature of the urethral defect (obliterative or Endoscopic repair
non-obliterative), length of the defect, presence
of complicating factors (eg, urethral cavitation, fis- Delayed endoscopic repair of PFUDDs was
tulae), and, to some degree, the treatment philoso- first described by Sachse in 1974 [38] and arose
phy and experience of the surgeon. Generally, a out of the dissatisfaction of some authors with
period of 3 to 6 months is allowed to pass follow- open urethroplasty [39]. It is certainly only ap-
ing the initial injury and SP tube placement. This plicable for PFUDDs that are are of short length
allows for the resorption of the retropubic hema- [40]. The technique generally involves a combined
toma and descent of the bladder and prostate. antegrade and retrograde ‘‘above and below’’ ap-
Radiographic studies are needed to identify the proach. As originally described, urethral continu-
location and length of the defect as well as any ity was established by passage of an antegrade
other pathology (eg, fistula, bladder calculi) that metal sound through the suprapubic tract and ret-
would need to be addressed at the time of repair. rograde incision toward the sound with a DVIU
A combined retrograde urethrogram antegrade [39]. Advances in endoscopic technology have
cystogram (‘‘up and down o-gram’’) is performed allowed the placement of rigid or flexible ante-
for this purpose (Fig. 5) [1]. If verification of radio- grade endoscopes, enabling a ‘‘cut to the light’’
procedure to re-establish urethral continuity, fol-
lowed by urethral dilatation and placement of a
catheter [41]. The use of C-arm fluoroscopy can
assist in planar orientation to ensure proper scope
alignment [42]. The endoscopic placement of hol-
low needles and guide wires through the scar prior
to incision allows the precise identification of the
area of continuity and thus the deliberate position-
ing of incisions [43]. Alternatively, balloon dilata-
tion over a guide wire can be performed without
formal DVIU [44]. Some urologists advocate resec-
tion of scar tissue [45] while others do not [42]. The
end result is the re-establishment of urethral conti-
nuity through the scar of the PFUDD. The cathe-
ter is then left in situ for 4 to 6 weeks.
While the procedure is often able to re-establish
urethral continuity, re-stricturing following cathe-
ter removal is common. Rates of 35% to 100%
have been reported, necessitating additional endo-
scopic procedures [41–49]. Because of this tendency
to recurrence, several authors routinely performed
elective DVIU following catheter removal or had
Fig. 5. A combined cystogram and retrograde ureth-
patients perform CIC in an effort to prevent stric-
rogram in a patient with an obliterative posterior
ture recurrence [43,44,48]. Nevertheless, strictures
urethral stricture. This study identifies a 3-cm oblitera-
tive segment. The posterior urethra fills down to the still tended to recur. It has been reported that
obstruction; however, earlier in the study, a competent the urethra tends to stabilize within 1 year of this
bladder neck was noted. (From Webster GD. Manage- aggressive endoscopic management, however
ment of complex posterior urethral strictures. Probl [45,46,49]. While the procedure does not seem to
Urol 1987;1:307.) worsen incontinence or impotence rates compared
G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441 435

to other types of management [42,45], significant • Further circumferential mobilization of the


bleeding and rectal injury have been associated distal urethra as far as the suspensory liga-
with the procedure, underscoring the importance ment of the penis. To prevent chordee, the
of proper patient selection, instruments, and tech- dissection should not extend beyond the liga-
nique [43,45]. Furthermore, the potential exists for ment, which can be incised to facilitate ure-
traumatizing the anterior urethra and jeopardizing thral elongation. After this mobilization, the
its elasticity to a degree that precludes subsequent healthy adult urethra can be stretched as
anastomotic urethroplasty [50]. Goel et al did not much as 2 to 3 cm, which proves sufficient
find this to be the case in their 3 patients who for anastomosis in 8% of the authors’ cases
required urethroplasty following prior endoscopic [55].
repair, however [43]. • Separation of the proximal 4 to 5 cm of the
corporal bodies beginning at the level of the
crus distally, dissecting in the relatively blood-
Open urethoplasty for PFUDD
less plane between them (Fig. 6C). The urethra
Perineal anastomotic urethroplasty can be laid between the separated corporal
While there is no panacea for the management bodies, which can shorten the distance for
of posterior urethral strictures, it is generally anastomosis by 1 to 2 cm and is sufficient
agreed that the optimal procedure is a one-stage for anastomosis in 41% of cases [55].
anastomotic repair, preferably performed through • Inferior pubectomy. A 1.5 to 2 cm wide
the perineum alone [50–52]. This repair is remark- wedge of bone can be excised from the infer-
ably versatile and, by elaborating it as the authors ior surface of the pubis exposed by corporal
shall describe, one can deal successfully with long separation (Fig. 6D). Routing the mobilized
obliterative strictures. It is only uncommon, extre- urethra between the separated corpora and
mely complex strictures that should require an through the bony defect will further shorten
abdominoperineal approach or substitution ure- the distance to the prostatic urethra by 1 to
throplasty [53,54]. 2 cm and facilitates anastomosis in 28% of
The perineal anastomotic repair commences cases [55].
with perineal exposure of the bulbar and posterior • Supra-crural re-routing. If the urethra still
urethra facilitated by a perineal Book-Walter re- appears to be too short after the three pre-
tractor or perineal OmniTrac retractor. The first vious maneuvers, the urethra can be re-routed
step of the procedure is circumferential mobiliza- around the lateral surface of a corporal body
tion of the bulbar urethra as far proximally as (Fig. 6E). It is necessary to create a tunnel in
the obliterated segment (Fig. 6A). The proximal the bone beneath the corporal body and com-
urethra is transected at the point of obliteration, municate this with the tunnel created by infer-
and the urethra is then mobilized distally to a ior pubectomy. The urethra is then laid in this
few centimeters distal to the crus (Fig. 6B). pathway, re-routing it around the corporal
A descending urethral sound is passed through body, which shortens the distance to the anas-
the suprapubic cystostomy and negotiated by tomosis by 1 to 2 cm. This is usually sufficient
‘‘feel’’ through the bladder neck and into the prox- for the final 23% of cases [55].
imal urethra. If the stricture is short and pelvic
floor fibrosis minimal, the tip of the sound can be
Anastomosis
palpated easily in the dissection in the perineum.
In these circumstances a one-stage perineal anasto- Regardless of the approach, the bulbar urethral
mosis can usually be assured. The pelvic floor scar end is spatulated to achieve an anastomosis exceed-
is incised perineally until the tip of the sound is ex- ing 40 French in caliber, and the anastomosis is
posed and the prostatomembranous urethra spa- performed with interrupted 4–0 polyglycolic acid
tulated posteriorly. The verumontanum should be sutures over a supporting 12 to 16 French fene-
visible in the floor of the spatulated opening. At strated silastic catheter. The anastomosis is facili-
this point it will be apparent whether a simple tated by a long nasal speculum, and all of the
anastomosis will be possible or if further maneu- sutures are inserted commencing at the 12 o’clock
vers (see below sections) will be necessary to achieve position and proceeding clockwise before being
a tension-free anastomosis [53,54]. These maneu- tied individually in the same order that they were
vers are performed sequentially, as needed to inserted. The sutures are inserted using a needle
achieve urethral length, and include: modified into a J shape, which is advanced through
436 G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441

Fig. 6. Repair of posterior urethral stricture. (A) Through a perineal incision the urethra is circumferentially mobilized
and released from its posterior attachments to the perineal body. (B) The proximal urethra is transected at the level of the
stricture and then dissected distally as far as the suspensory ligament of the penis. (C) The corporal bodies are separated
for approximately 5 cm beginning at the crus distally, exposing the dorsal penile vessels and inferior surface of the pubis.
(D) The undersurface of the pubis can be excised with an osteotome or bone rongeur. The urethra will now course
between the separated corporal bodies and through the bony defect to the prostatic apex, considerable shortening the
distance. (E) Mobilized urethra can be transferred around a corporal body and through the bony defect on its way to the
prostatic apex. This further shortens the distance and permits a tension-free anastomosis in difficult cases. (From Webster
GD. Management of complex posterior urethral strictures. Probl Urol 1987;1:308–9.)
G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441 437

Fig. 6 (continued )

the prostatic urethral edge from outside to inside. Features that might make perineal anastomotic
The point of the needle is retrieved within the pro- repair inappropriate
static urethra and advanced until clear and then
The majority of PFUDDs are manageable with
withdrawn.
a one-stage perineal anastomotic urethroplasty.
Even if the anastomosis is performed perine-
Factors that might render a one-stage perineal re-
ally, a suprapubic cystostomy is used in addition
pair inappropriate occur in \5% of all cases. In
to a fenestrated urethral catheter; periurethral and
some of these complex cases a one-stage anasto-
perineal drainage is by a suction drain. The drain is
motic repair can still be accomplished by a one-
usually removed on the first day post-operatively
stage abdominoperineal anastomotic approach,
and the patient is allowed immediate ambulation
but in others a one- or two-stage substitution ure-
and discharged on the first or second post-opera-
throplasty might be necessary. These complicating
tive day. The urethral catheter stays in place for
factors include the following.
3 weeks, at which time a peri-catheter RUG is per-
formed confirming the absence of extravasation. Long urethral defect
The supra-pubic catheter is removed following a
successful voiding trial. Patients are then followed Using the authors’ progressive approach, even
with serial RUGs at 3 and 12 months, then as defects as long as 7 to 9 cm can be managed peri-
needed. neally. However, some surgeons might be intimi-
While re-stricture rates of up to 57% have been dated by the depth or inaccessibility of the
reported by some [26], in expert hands, results with anastomosis and resort to an abdominoperineal
this progressive perineal approach have been excel- approach. The best management might be preven-
lent with success rates, defined as not requiring tion with early intervention in patients who have
additional instrumentation/procedures, achieved massive pelvic hematoma following initial injury.
in >90% of patients [50,56,57]. The incidence of
Chronic periurethral cavity
de novo erectile dysfunction is low [50,57], and if
the patient has a competent bladder neck he will The pelvic hematoma that follows pelvic frac-
generally be continent [58,59]. This approach can ture injuries can liquify and evacuate through the
also be used successfully in the majority of salvage urethra, resulting in a pelvic floor cavity that might
posterior urethroplasties in patients who have had epithelialize and communicate with the urethra.
prior failed repairs [56,60]. This (rarely) can become the site of chronic sepsis
438 G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441

and stone formation and might predispose to fistu- anastomosis. If it is felt that the anterior urethra is
lization into the rectum or osteomyelitis. While too precarious, a staged substitution urethroplasty
these hematomas can sometimes be repaired peri- might be required.
neally, often an abdominoperineal approach is
Factors limiting surgical access
required for complete excision and placement of
an omental pedicle to fill the space once urethral Major lower torso trauma can result in hip fixa-
anastomosis has been completed. tion, which can make it impossible to achieve the
lithotomy position necessary for good perineal dis-
Fistula section.
Complicated fistula between the bladder, rec- History of failed repair
tum, and urethra require careful radiographic
identification, and their excision might require an Aside from the more complex cases it is prob-
abdominoperineal approach with omental buttres- able that the majority of posterior urethroplasty
sing. Fistula into the rectum might necessitate a failures are avoidable. The failures are generally
protective sigmoid colostomy. secondary to an inadequate anastomosis as a result
of poor exposure and visibility of the apex of the
Bladder neck incompetence prostate and inadequate mobilization of the ure-
Following posterior urethral injury, continence thra. The majority of patients who have failed a
relies on the functional integrity of the bladder prior repair are still salvageable with the authors’
neck; the distal urethral mechanism is often dis- progressive perineal approach, however. In some
rupted as a natural consequence of trauma. The cases an abdominoperineal or staged substitution
bladder neck might be non-functional either as a repair might be necessary.
result of unrecognized or unrepaired injury at the Abdominoperineal approach
time of pelvic fracture, prior resection or prosta- While the majority of posterior urethroplasties
tectomy, or simply because of fixation in the peri- can be performed through the perineum alone, as
prostatic retropubic scar. In this event a successful previously mentioned there will be the occasional
posterior urethroplasty can be followed by incon- patient in whom a combined abdominoperineal
tinence. Bladder neck function can be assessed pre- approach is warranted. The abdominoperineal
operatively by endoscopy and cystography. An approach involves both perineal and retropubic
open bladder neck on cystogram and an obvious exposure of the urethra and prostate with removal
sector defect or scar on cystoscopy might suggest of a segment of pubic bone to facilitate exposure.
an incompetent bladder neck [58]. In such cases The main indication for this approach is to im-
an abdominoperineal approach has been sug- prove visualization and to facilitate the removal of
gested so the bladder neck can be repaired or lysed fistulous tracts and periurethral epithelialized cav-
from surrounding fibrosis at the same time as ure- ities, the excision of scar tissue at the prostatic
throplasty to prevent incontinence [59]. Accurate apex, and the performance of a tension-free ana-
preoperative diagnosis of an incompetent bladder stomosis [14,61].
neck is difficult, however, and as such a more con- The patient is positioned in the lithotomy posi-
servative approach, with primary posterior ure- tion but prepped for a possible abdominal explora-
throplasty followed by evaluation of bladder neck tion. The initial dissection is perineal and the
function if post-operative incontinence ensues and urethra is transected at the level of obliteration.
delayed bladder neck repair or insertion of artifi- The first three steps of the progressive perineal
cial urinary sphincter, is the authors’ recommen- approach are performed, including inferior wedge
dation [58,59]. pubectomy. If retropubic exposure is needed, a
lower midline abdominal incision is made down
Associated anterior urethral disease
to the base of the penis. The prevesical or retropu-
The perineal anastomotic repair requires bic space is dissected down to the level of the pros-
the anterior urethra to be elastic and mobilizable tatic apex, staying close to the periosteum of the
based on its retrograde blood supply. Prior ante- retropubis, until communication is made with the
rior urethral stricture or surgery and hypospadias perineal dissection. It is helpful to open the blad-
can interfere with both the vascularity and elasti- der high on the anterior wall so a finger can be used
city of the anterior urethra such that it might not to help direct the retropubic dissection and avoid
be possible to adequately mobilize it for a primary the bladder neck. Waterhouse described excising
G.D. Webster, M.L. Guralnick / Urol Clin N Am 29 (2002) 429–441 439

an entire anterior wedge of pubis using a Gigli saw The delayed management of pelvic fracture ure-
[62]; however, equally good access is achieved by thral distraction defects can be approached endo-
partial removal of the posterior surface of the scopically or by open urethroplasty; each method
pubis using a Capener’s gouge [63]. Inferior wedge has many advocates. It is evident that when man-
pubectomy will have been completed perineally, aged endoscopically most patients will require
and this—combined with retropubic bone remo- some form of additional procedure for recurrent
val—will provide wide anterior access, which facil- stricture, but this is often an acceptable outcome.
itates anastomosis and access to the pelvic floor to In expert hands a one-stage perineal anastomotic
manage the complicating features that were the urethroplasty is successful in treating PFUDDs
indication for this approach. At the completion in the majority of patients without the need for
of the procedure the bladder neck and anastomosis subsequent procedures. Only in rare situations will
should be wrapped with an omental flap to pre- either a combined abdominoperineal transpubic
serve functional mobility as well as facilitate future approach or a one- or two-stage substitution ure-
re-exposure if needed. throplasty be required.
This approach is very successful (greater than
85% success rate) in expert hands with few compli-
cations [14,50,64,65]. A re-stricture rate of ~50% References
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