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The Fixation of Dental

Implants

4B16 Biomechanics of Tissues and Implants

Tom Eastaway (07485476)


Introduction

Teeth are primarily lost as a result of gum disease [ CITATION Orl11 \l 2057 ] . Other causes
include injury, congenital defects and cavities. Missing teeth should be replaced with
prosthetics for both health and cosmetic reasons. A missing tooth can leave the gum and
jaw bone vulnerable to damage, and can cause difficulties in biting and chewing which may
eventually lead to malnutrition. A visible gap in teeth may also cause people to become self-
conscious about smiling or talking [ CITATION ADi11 \l 2057 ] . A missing tooth can also cause
the adjacent teeth to shift and make them more susceptible to damage and loss [ CITATION
Orl11 \l 2057 ].

An implanted replacement tooth consists of an implant which is set into the jaw bone
(endosseous) and an external crown attached to it [ CITATION Leo70 \l 2057 ] . An endosseous
dental implant is a screw, typically metal, which acts as an artificial root. Implants are widely
seen as being preferable to dentures since they do not slip, click, or have to be removed for
cleaning.

In this report the current endosseous dental implant practice is described, and the merits of
this technique and potential improvements are discussed.

Dental Implantology Background

Modern dental implants are typically made of titanium [ CITATION ADi11 \l 2057 ]. Most
metals corrode in the presence of bodily fluids and tissue, releasing ions which may have
negative impacts on health or lead to implant rejection. Titanium is recognised as being
completely immune to corrosion in the body, as are many titanium alloys [ CITATION AZO03 \l
2057 ]. Combined with its high strength-to-weight ratio, among other factors, this has led to
titanium being the material of choice for dental implants for several years.

Early designs of endosseous dental implants resembled the shape of a natural tooth root,
since it was assumed that this design would be the most effective [ CITATION Leo70 \l 2057 ].
However it is now known that a screw is a more effective shape since it provides a grip onto
which bone grows (osseointegration). The concept of osseointegration was first proposed by
Swedish orthopaedic surgeon Per-Ingvar Brånemark in the 1960s (Depprich et al., 2008).
Metallic implants must be rigidly fixed into living bone, with direct contact between the
surface of the implant and the bone itself (i.e. with no intermediate soft-tissue interface).
Current Typical Implantation Procedure

The process of dental implantation begins with an assessment of the viability of the patient
– factors such as age (bones not yet being fully developed) and whether or not the patient
smokes are taken into account, and an X-ray and CT scan are performed. In instances of
insufficient bone or gum tissue a separate graft procedure may be required before
implantation can take place [ CITATION ADi11 \l 2057 ].

The implantation of the endosseous implant is done in a single sitting, excluding the addition
of a crown which is done after successful osseointegration is observed (after three to six
months). After the administration of either a local anaesthetic or a sedative [ CITATION
ADi11 \l 2057 ], the first step of a dental implantation procedure is the drilling of a small-
diameter pilot hole in the jaw bone using a bur (a hard metal alloy dental drill bit) or
trephine (a small crown saw) [ CITATION Leo70 \l 2057 ]. Particular care is required during
pilot hole drilling since inaccuracy can potentially damage vital structures such as nerves in
the bone. Surgical guides based on CT scans are often made to aid oral surgeons [ CITATION
ADi11 \l 2057 ].

The pilot hole is gradually widened using progressively wider helical burs [ CITATION Leo70 \l
2057 ]. The implant screw is placed in the widened hole and to aid recovery and
osseointegration either a healing cap (a protective cover screw fitting) or an abutment and a
temporary crown fitting. The gum is sutured over the healing cap, usually using self-
dissolving stitches [ CITATION Den11 \l 2057 ] . If the abutment is not placed during the initial
procedure, it is placed after healing provided that the implant is successful [ CITATION
ADi11 \l 2057 ] . At this time the permanent crown is made from an impression, shaded to
match the existing teeth and attached to the abutment [ CITATION Den \l 2057 ].

Emerging Practices and Technologies

Image-Guided Implant Placement

In order to overcome the difficulty of drilling accurate pilot holes, an emerging practice is to
use image-guided implant placement technology, of which two emerging types exist. The
first uses computer-designed surgical splints made using sterolithography (the fabrication of
solid objects by solidifying layers of UV-curable resin on top of one another). These custom-
designed splints greatly reduce the duration of an operation, but have the disadvantage that
they cannot be adjusted during the operation. The second technology is real-time image-
guided navigation. This gives the oral surgeon a much better view of the procedure and
allows adjustments to be made during the procedure if the implant position deviates from
the computer-planned position. However the cost of the equipment required for real-time
navigation is often prohibitive [ CITATION Che07 \l 2057 ].
Implant Material

Research into materials for implants is in progress, with two main aims: Firstly to improve
implant success rates by maximising the effectiveness of osseointegration, and secondly to
give the appearance of a natural bone colour and translucency in case any part of the
implant below the crown is visibly exposed.

Titanium and its alloys are effective osseointegrators since a passive oxide layer forms on
the surface of the implant. This layer protects the implant from further oxidation [ CITATION
Cas06 \l 2057 ] and creates a surface topography which has proven to give an
osseointegration success rate of over 95% in recent years [ CITATION Che07 \l 2057 ]. However
the disadvantage of titanium is that its appearance does not match that of teeth. Zirconia
(also known as zirconium oxide or zirconium dioxide, ZrO 2) is an alternative material viable
for use in dental implants, since it has high fracture toughness, good chemical resistance
and is also biocompatible [ CITATION New09 \l 2057 ] – zirconia has been shown good results
for artificial ball heads in total hip replacements (Depprich et al., 2008). It may be preferable
for patients because its opaque white colour is virtually indistinguishable from the colour of
teeth, and because some patients may feel more comfortable with a ceramic implant than
with a metal implant [ CITATION New09 \l 2057 ].

A study by Depprich et al. (2008) comparing the osseointegration effectiveness of titanium


and zirconia implants found that bone-to-implant contact was slightly better for titanium
implants after 1, 4 and 12 weeks, but concluded that the difference was not statistically
significant (Depprich et al., 2008).

Single-Stage Treatment

It is now possible for placement of the implant and of the artificial crown to be performed in
a single sitting. In the past it was necessary to fit the implant and wait for osseointegration
to occur, before attaching the abutment and crown at a later date (after up to six months).
However the advent of the use of 3D CT scans in implantology has allowed the development
of surgical protocols and products (such as Nobel Biocare’s Immediate Function) which suit
all indications and bone types. This flexibility allows oral surgeons to fit the implant and the
crown in the same visit, giving patients functioning teeth immediately [ CITATION Cle11 \l
2057 ].

Tissue Engineering – An Alternative to Implants

Dental implants can fail over time due to their inability to remodel with their surroundings,
as can be the case with all synthetic implants [ CITATION Rah05 \l 2057 ]. However,
alternative to artificial dental implants may be possible in the very near future. A new
approach under investigation is to use mesenchymal stem cells, harvested from deciduous
teeth, which may be implanted in vivo with a temporary biocompatible hydrogel scaffold.
Studies have shown successful growth of teeth in immunodeficient mice and also in an adult
human tooth socket [ CITATION Mao08 \l 2057 ].

The use of stem cells as a replacement has the potential not only to eliminate some of the
factors which lead to failure of implants, but also to improve patients’ viability for tooth
restoration, since a similar approach may be adopted as an alternative to bone and tissue
grafting in patients with insufficient periodontal tissue for tooth restoration.

Conclusion

Dental implants have reached a success rate of up to 95%. Possible reasons for failure
include insufficient bone or tissue mass at the implant site and inaccurate drilling during the
implantation procedure. In some cases grafting can be performed to repair the tissue at the
implant site, although this requires an extra procedure. Recent developments in 3D CT
scanning are helping to overcome the problems of insufficient tissue and drilling difficulties.
Ideally all dental implant procedures should use real-time imaging technology for surgical
guidance, but this is not possible due to the cost of the equipment required.

Implant material research is generally geared towards the use of zirconia. Since this is a
relatively new material in dental implants it may be necessary to further investigate its long-
term effectiveness. The only apparent advantage of the material is its colour, since its
performance over 12 weeks has been shown to be roughly equal to that of titanium and
titanium alloys. Pending further research, it appears that titanium is an adequate implant
material, since the colour of the implant itself should not be visible.

The established method of placing an implant and waiting for up to six months for
osseointegration is gradually being replaced by single-stage treatment which seems to
benefit the patient in terms of comfort, practicality and cost. Given current implant success
rates it appears to make sense in most cases to perform this type of procedure, provided
that the patient is made aware of the risks of failure.

In the coming years we can expect a paradigm shift in the treatment of tooth loss as
research progresses in regeneration by stem cell growth as an alternative to artificial
replacement. In the mean time advances in imaging and developments in more flexible
implant products promise the best chances of improving implant success rates.
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Appendices

Titanium implant screw. (Brånemark et al., 1983)

Artists impression of complete implant assembly (ClearChoice)


Implant planning on maxilla using Nobel Guide software (Cheung, 2007)

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