Nama : Almira Azalia Fridayanti

NIM : 1800023122

Kelas : 6C

TUGAS EBM

PERHITUNGAN PARAMETER OUTCOME

1. Judul Jurnal: Antibiotic Prophylaxis and Recurrent Urinary Tract Infectionin Children.
Penulis : Jonathan C Craig 1, Judy M Simpson, Gabrielle J Williams, Alison Lowe,
Graham J Reynolds, Steven J McTaggart, Elisabeth M Hodson, Jonathan R Carapetis, Noel
E Cranswick, Grahame Smith, Les M Irwig, Patrina H Y Caldwell, Sana Hamilton, Leslie
P Roy.
Perhitungan parameter out come meliputi RR, ARR, RRR, dan NNT/NNH:
 EER= 0,157
 CER= 0,190
 RR= EER/CER = 0,157/0,190 =0,826
 ARR= CER-EER = 0,190-0,157 = 0,033
 RRR= CER-EER/CER = 0,190-0,157/0,190 = 0,173
 NNT= 1/ARR= 30,30

Jadi dari hasil perhitungan ARR dan NTT dapat disimpulkan bahwa dari 9 anak anak
yang di treatment dengan antibiotic trimetophrim sulfametoksazol, terdapat 1 anak yang
mengalami ISK berulang

2. Judul : Combination of Probiotics and Antibiotics in the Prevention of Recurrent Urinary

Tract Infection in Children
Penulis : Mohammad- Javad Mohseni MD, Zahra Aryan MPH, Sahra Emamzadeh-Fard
MD, Koosha Paydary MD, Vahid Mofid MSc,
Perhitungan parameter out come meliputi RR, ARR, RRR, dan NNT/NNH:
 EER=0,69
 CER=0,46
  RR= EER/CER =0,69/0,46 =1,5
 ARR= CER-EER = 0,46-0,69 = - 0,23
 RRR= CER-EER/CER = 0,46-0,69/0,46 = -,05
 NNT= 1/ARR= 4,347

Kesimpulan : Jadi dari hasil perhitungan ARR dan NTT dapat disimpulkan bahwa dari 17
anak anak yang di treatment dengan kombinasi antibiotic dan probiotik, terdapat 1 anak
yang mengalami ISK Berulang.

3. Judul : Long-Term Cost-Effectiveness of Clopidogrel Given for Up to One Year in Patients

With Acute Coronary Syndromes Without ST-Segment Elevation
Penulis : William S. Weintraub, MD, FACC, Elizabeth M. Mahoney, SCD, Andre Lamy,
MD,Steven Culler, PHD, Yong Yuan, PHD, Jaime Caro, MD, Sylvie Gabriel, MD, Salim
Yusuf, MD, FACC
Perhitungan parameter out come meliputi RR, ARR, RRR, danNNT/NNH:
 EER= 0,5327
 CER = 0,6026
 RR = EER/CER =0,5327 / 0,6026 = 0,884
 ARR = CER-EER =0,6026 - 0,5327 = 0.0699
 RRR = CER-EER/CER =0,6026 - 0,5327/0,6026 =0,115
 NNT = 1/ARR =14,30

4. Judul Jurnal: Cost-Effectiveness of Long-Term Ticagrelor in Patients With Prior

Myocardial Infarction
Penulis : Elizabeth A. Magnuson, SCD, Haiyan Li, MS, Kaijun Wang, PHD, Katherine
Vilain, MPH, Ali Shafiq, MD, Marc P. Bonaca, MD, MPH, Deepak L. Bhatt, MD, MPH,
Marc Cohen, MD, Philippe Gabriel Steg, MD, Robert F. Storey, MD, Eugene Braunwald,
MD, Marc S. Sabatine, MD, MPH, David J. Cohen, MD, MSC,
Perhitungan parameter out come meliputi RR, ARR, RRR, danNNT/NNH:
 EER=2,9
  CER=3,4
 RR =EER/CER
=2,9/3,4=0,852
 ARR =CER-EER
=3,4-2,9=0,5
 RRR =CER-EER/CER
=3,4-2,9/3,4 =0,147
 NNT=1/ARR=2

5. Judul Jurnal: Nitrous Oxide/ Oxygen Plus Acetaminophen Versus Morphine In ST

Elevation Myocardial Infarction : Open-Label , Cluster-Randomized,Non-Inferiority
Study.

Penulis : Sandrine Charpentier, Michel Galinski, Vincent Bounes, Agnès Ricard-Hibon,

Carlos El-Khoury, Meyer Elbaz, François-Xavier Ageron, Stéphane Manzo-Silberman,
LouisSoulat, Frédéric Lapostolle, AlexandreGérard, Delphine Bregeaud, Vanina Bongard,
Eric Bonnefoy-Cudraz

Perhitungan parameter out come meliputi RR, ARR, RRR, danNNT/NNH:

 NNT CER = 73,6%

 EER = 51,7%
 ARR = (EER-CER)
= (51,7%-73,6%) = 21,9%
 NNT = 1/ARR
= 1/0,219 = 4,56 = 5
 NNH CER = 16,0%
 EER = 18,8%
 ARR = (EER-CER)
= (18,8-16,0%) = 2,8%
 NNH = 1/ARR
= 1/0,028 = 35,71 = 36
 Jadi, dari hasil perhitungan ARR dan NTT dapat disimpulkan bahwa 36 pasien yang
mendspatkan terapi dengan morfin dan 1 orang mengalami efek samping obat berupa
muntah

6. Judul Jurnal: Intra-Coronary Morphine Versus Placebo In The Treatment Of Acute ST-
Segment Elevation Myocardial Infarction: The MIAMI Randomized Controlled Trial.

Penulis : Philippe Le Corvoisier, Romain Gallet, Pierre-François Lesault, Etienne

Audureau, Muriel Paul, Julien Ternacle, Saïd Ghostine, Stéphane Champagne, Raphaele
Arrouasse , Dalila Bitari, Gauthier Mouillet, Jean- Luc Dubois-Randé, Alain Berdeaux ,
Bijan Ghaleh, Jean-François Deux andEmmanuel Teiger

Perhitungan parameter out come meliputi RR, ARR, RRR, dan NNT/NNH:

 CER = 15,6%
 EER = 18,6%
 ARR = (EER-CER)

= (18,6%-15,6%) = 3%

 NNT = 1/ARR
= 1/0,03 = 33,33 = 33

Jadi dari hasil perhitungan ARR dan NTT dapat disimpulkan bahwa dari 33 pasien
yang di treatment dengan kombinasi morfin dan placeo, terdapat 1 pasien yang mengalami
myocardial infraction.