Order:
#84434 Hepatitis C Virus Genotype After
Amplification, Serum
and
#83142 Hepatitis C Virus RNA Detection and
Quantitation by Real-Time PCR, Serum
HCV genotype HCV genotype
2 or 3 1, 4, 5, or 6
No detectable HCV RNA #83142 Hepatitis C Virus RNA Detection biopsy in 3-5 years
HCV RNA detected and Quantitation by Real-Time PCR, Serum
for “rapid virologic response” (RVR)
Poor treatment Excellent treatment
tolerance tolerance No detectable HCV RNA
HCV RNA detected
Yes No No Yes
Excellent treatment Additional 8 weeks of
tolerance treatment (12 weeks total)
Additional 12 weeks Additional 20 weeks Additional 44 weeks
of treatment of treatment of treatment No Yes
(16 weeks total) (24 weeks total) (48 weeks total)
After 12 weeks total treatment: repeat
#83142 Hepatitis C Virus RNA Detection
and Quantitation by Real-Time PCR, Serum
for “early virologic response” (EVR)
When treatment ends: repeat
#83142 Hepatitis C Virus RNA Detection Additional 20 weeks Additional 44 weeks
No detectable If <100-fold (<2 log)
and Quantitation by Real-Time PCR, Serum of treatment of treatment
HCV RNA decrease in HCV RNA
for “end-of-treatment (EOT) response” (24 weeks total) (48 weeks total)
Sustained Relapser
virologic See insert
Legend
response (SVR)
achieved
n Real-Time PCR Testing
IFN: interferon or pegylated interferon
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