Drug Mechanism of Indication Contraindication Adverse reaction Nursing

action consideration

Generic name: Provide elemental Iron deficiency Contraindicated in GI: nausea, Gi upset may be
Ferrous sulfate iron, essential patients with epigastric pain, related to dose
component in As a supplement hemosiderosis, vomiting,
Brand name: formation of during pregnancy hemolytic, anemia, constipation, Between-meal
Feosol hemoglobin peptic, ulceration, black stools, doses are
ulcerative colitis, or diarrhea, anorexia preferable but drug
Category: regional enteritis can be given with
Helmintics and in those Other: some foods,
receiving repeated temporarily although
Oral, 1 tab, TID blood transfusions stained teeth from absorption may be
liquid forms decreased
 Drug Mechanism of Indication Contraindication Adverse reaction Nursing
action consideration

Generic name: stimulates uterine for the prevention contraindicated in Cardiovascular: Be alert for adverse
Methylergon smooth muscles and control of patients hypertension, reactions and drug
ovine which stimulates excessive bleeding hypersensitive to temporary chest interactions
contraction following vaginal methylergonovine pain, palpitation
Brand name: thereby shortens childbirth or CNS: This drug should
Methargine the third stage of any component of hallucinations, be
labor the dizziness, seizure, used extremely
Category: formulation. headache carefully because
Uterine stimulant Gastrointestinal: of its
ergot alkaloids are Nausea, vomiting, potent
IV: contraindicated with diarrhea, foul vasoconstrictor
0.2 mg after potent inhibitors of taste action. I.V. use
delivery of CYP3A4 (includes Local: may
anterior protease inhibitors, Thrombophlebitis induce sudden
shoulder, azole antifungals, Otic: Tinnitus hypertension and
after and Renal: Hematuria cerebrovascular
delivery of some macrolide Respiratory: accidents. As a last
placenta, or antibiotics); Dyspnea, nasal resort, give I.V.
during hypertension; congestion slowly
puerperium; toxemia; pregnancy Miscellaneous: over several
may be Diaphoresis minutes
repeated as and monitor blood
required at pressure closely.
intervals of
2-4 hours
 Drug Mechanism of Indication Contraindication Adverse reaction Nursing
action consideration

Generic name: Causes potent and induction of labor Contraindicated in Cardiovascular: Monitor and record
Oxytocin selective at term; control of patients hypertension; uterine
stimulation of postpartum hypersensitive increased heart contractions,
Brand name: uterine and bleeding; to the drug or any of rate, heart rate, BP,
Pitocin mammary gland adjunctive therapy its component. systemic venous intrauterine
smooth muscles in management of return, and pressure,
Category: Which producing abortion cardiac fetal heart rate, and
Antihemorrhagic sustained output, and blood loss q15.
contractions and arrhytmias
I.V.: 10-40 Induces labor and CNS: Monitor I/O.
units by I.V. milk ejection and seizures, Antidiuretic effect
infusion in reduces post coma from water may
1000 mL of partum intoxication lead to fluid
intravenous bleeding Gastrointestinal: overload,
fluid at a Nausea, vomiting, seizures, and coma
rate GU:
sufficient to titanic uterine never give oxytocin
control contractions, simultaneously by
uterine atony. abruption more
placentae, than one route.
impaired
uterine blood have 20% solution
flow, magnesium sulfate
pelvic hematoma available for
Hematologic: relaxation
afibrinogenemia of the
Respiratory: myometrium.
anoxia, asphyxia
if contractions are
less
than 2 minutes
apart, if
they’re above
50mm Hg
,or if they last
90seconds
or longer, stop
infusion,
and turn patient on
her
side, and notify
prescriber.
 Drug Mechanism of Indication Contraindication Adverse reaction Nursing
action consideration

Lidocaine A class IB Ventricular Contraindicated CNS: confusion, • Give MI

Hydrochloride antiantiarrhythmic arrhythmias in pt light-headedness, injections in the
Brand name: that decreases the caused by MI, hypersensitive restlessness, deltoid muscle
LidoPen, Auto- depolarization, cardiac to the amide- stupor, tremor, only.
injector, Xylocaineautomaticity, and manipulation, type local lethargy, seizure • Monitor
excitability in the cardiac glycosides anesthetics. CV: hypotension, isoenzymes
Classification: ventricles during bradycardia, new when using IM
Antiantiarrhythmic the diastolicphase In those with or worsen drug for
by direct action on Adams-Stokes arrhythmia, suspected MI.
Adults: 50-100 mg the tissues, syndrome, cardiac arrest. A patient who
at rate of 25-50 especially the Wolff- EENT: tinnitus, has receive IM
mg/min. Bolus is purkinji network Parkinson- blurred or double lidocaine will
used to establish White vision show a severe
rapid therapeutic syndrome, and GI: Vomiting enfold increase
plasma levels. severe degrees Respiratory: in CK level.
Repeat if of SA, AV and respiratory Such an
necessary after 5- intraventricular depression and increase
min interval. block in the arrest originates in the
Onset of action is absence of an Skin: soreness at skeletal
10 sec. Maximum artificial injection site muscles,
dose/hr: 200-300 pacemaker. Other: • Monitor pt for
mg. anaphylaxis toxicity
Monitor pt
response,
especially blood
pressure
 Drug Mechanism of Indication Contraindication Adverse reaction Nursing
action consideration

Mefenamic Acid Mefenamic acid used for the relief Mefenamic acid is The most common Assess patients
Classification: has analgesic, anti- of mild to contra-indicated in side-effects involve who develop severe
Non- Steroidal inflammatory and moderate pain in patients with known the gastro-intestinal diarrhea and
Anti inflammatory anti-pyretic acute and chronic sensitivity and in system and include vomiting for
Drug properties. It conditions patients who forms of dyspepsia, dehydration and
inhibits the including: pain of respond to aspirin upper gastro- electrolyte
synthesis of traumatic, arthritic and aspirin-like intestinal imbalance.
500 mg of prostaglandins. or muscular medicines with discomfort as well
mefenamic acid Mefenamic acid origin; sensitivity reactions as peptic ulceration Lab tests: With
three times daily shows central and dysmenorrhoea; like and gastro-intestinal long-term therapy
with food. The peripheral action headache and bronchoconstriction, bleeding. Gastric (not recommended)
dosage may be and it owes these dental pain. skin rashes and irritation may be obtain periodic
reduced to 1 properties to its urticaria. reduced by taking complete blood
capsule (250 mg) capacity to inhibit reduces blood loss medication during counts, Hct and
three times daily. cyclooxygenase. in menorrhagia Mefenamic acid is meals. Headache, Hgb, and kidney
where contra-indicated in drowsiness, function tests.
menorrhagia is patients with peptic dizziness,
due to ovulatory ulceration or having nervousness and
dysfunctional a history of gastro- visual disturbances
bleeding. Uterine intestinal bleeding have been reported.
and other and or inflammatory Therapy should be
pathology should bowel disease. discontinued if
first be excluded Safety in pregnancy diarrhoea or skin
before prescribing and lactation has not rashes occur. Skin
 been established. rash may be a
also indicated as Do not use in sensitivity reaction,
an anti-pyretic in epileptic patients or and urticaria may
febrile conditions. in patients with also occur.
Mefenamic acid is impaired hepatic Reported
used for the function. haematological
treatment of post effects include
traumatic haemolytic
conditions such as anaemia,
pain, swelling and agranulocytosis,
inflammation, for pancytopenia,
a maximum period thrombocytopenia
of five days. or
thrombocytopenia
purpura and bone-
marrow aplasia.
Allergic
glomerulonephritis
has occurred as well
as abnormalities of
hepatic and renal
function. Therefore
blood counts and
monitoring of
hepatic and renal
function are advised
during prolonged
therapy with
Mefenamic acid.
Bronchoconstriction
may occur in
asthmatic patients
with aspirin
sensitivity.
Mefenamic acid
affects platelet
function and it may
enhance the effect
of anti-coagulant
therapy