C. Baku (x) Abs. Baku (y) Slope (b) Intercept (a) t (menit) Abs.

Sampel
9.82 0.3605 0.0633 -0.3610 5 0.4343
14.73 0.5753 r 10 0.5674
19.64 0.7738 0.9518 15 0.6529
24.55 0.9966 20 0.7058
29.46 1.7035 30 0.7348
45 0.7569
60 0.7835

Persamaan t vs ln (Wt~-Wt)
Slope Intercept K Disolusi t 1/2
-0.0636 1.0878 0.0636 10.8983

Grafik Perbandingan antara Waktu vs. Zat Aktif Tidak Terlarut

Waktu vs. ln (Wt~-Wt)
2.5

1.5

1
ln (Wt~-Wt)

0.5

0
0 5 10 15 20 25 30 35 40 45 50
-0.5

-1

-1.5
Waktu (menit)

Kurva Regresi Baku

Konsentrasi vs. Absorbansi
1.8
1.6
1.4 f(x) = 0.0632851323828921 x − 0.36098
R² = 0.905981379489884
1.2
Absorbansi

1
0.8
0.6
0.4
0.2
0
5 10 15 20 25 30 35
Konsentrasi (ppm)
 0.4
0.2
0
5 10 15 20 25 30 35
Konsentrasi (ppm)

PERHITU
Inovator Generik
t (menit) Rt-Tt (Rt-Tt)^2 1 + 1/7 (Σ(Rt-Tt)^2)
%Wt thdp Do %Wt thdp do
5 50.3912 50.3912 0.0000 0.00
10 67.8058 58.9088 8.8970 79.16
15 78.9925 78.8657 0.1268 0.02
20 85.9139 83.7274 2.1865 4.78
12.99
30 89.7082 88.6273
45 92.5998 91.3647
60 96.0801 95.0038
83.95
 PERHITUNGAN DISOLUSI PADA PANJANG GELOMBANG 238 NM
C. Sampel ( x caping) AUC (C. Sampel)
12.5666 31.4165
14.6698 68.0910
16.0208 76.7266
16.8567 82.1939
17.3150 170.8585
17.6642 262.3436
18.0845 268.1151
959.7452

%ED (Kons) 88.4501

%ED (Wt) 88.4501
%ED (Dosis) 79.9788

t (menit)
0
5
10
15
20
30
45

40 45 50

1.8

1.6
nsi 1.4

1.2

0.8
Abs. Baku (y)
Linear (Abs. Baku (y)) 0.6

0.4

0.2

0
5 10 15 20 25 30 35
30 35
30 35

PERHITUNGAN NILAI F2 (SIMILARITY FACTOR)

1/(√(1 + 1/7 (Σ(Rt-Tt)^2))) (1/(√(1 + 1/7 (Σ(Rt-Tt)^2)))x100)

0.28 27.74
UNGAN DISOLUSI PADA PANJANG GELOMBANG 238 NM
Wt AUC (Wt)
6.2833 15.7083
7.3349 34.0455
8.0104 38.3633
8.4284 41.0969
8.6575 85.4292
8.8321 131.1718
9.0423 134.0576
479.8726

C BAKU= 982

ln (Wt~-Wt)
Grafik Perbandingan antara Waktu
2.2019080577053 Waktu vs. %
1.51926953471065 120
1.03936597425805
0.535763927587537 100
0.0164799681188083
-0.45069625916625 80

-1.05546407346715
60
%Wt

40

20

0
0 10 20 30
Waktu (m

Column B
Linear (Column B)

10 15 20 25 30 35
log(1/(√(1 + 1/7 (Σ(Rt-Tt)^2)))x100) 50xlog(1/(√(1 + 1/7 (Σ(Rt-Tt)^2)))x100)

1.44 72.16
 Wt~-Wt ln (Wt~-Wt) %Wt %Wt (Dosis) Dosis-Wt ln (Dosis-Wt)
2.7589 1.0148 69.4883 62.8331 3.7167 1.3128
1.7074 0.5349 81.1181 73.3490 2.6651 0.9802
1.0318 0.0313 88.5887 80.1041 1.9896 0.6879
0.6139 -0.4879 93.2109 84.2836 1.5716 0.4521
0.3848 -0.9551 95.7448 86.5748 1.3425 0.2945
0.2102 -1.5599 97.6758 88.3209 1.1679 0.1552
0.0000 - 100.0000 90.4225 0.9577 -0.0432

ppm

t (menit)
Grafik Perbandingan antara Waktu dengan Zat Aktif Terlarut
Waktu vs. %Wt 0
5
10
15
20
30
45
60

t (menit)
0
0 20 30 40 50 60 70 5
10
Waktu (menit)
15
20
30
45
60
ln (C. Sampel)
2.5310
2.6858
2.7739
2.8247
2.8516
2.8715
2.8951

%Wt
Grafik Perbandingan antara Zat Aktif Terlarut terhadap Dosis dengan
0 Waktu
52.4470953509 Waktu vs. %Wt (Dosis)
70.5722145055 120

82.2153226026
100
89.4190701855
93.3681945693 80
%Wt (Dosis)

96.3776997031
60
100
40

%Wt 20

0
0
52.44709535093 0 10 20 30 40 50 60 70

70.57221450554 Waktu (menit)

82.21532260261
89.41907018547
93.36819456927
96.37769970313
100
t (menit) %Wt (Dosis)
0 0
5 50.391207641
10 67.805835405
15 78.992542195
20 85.913908151
30 89.708229753
45 92.59976449
60 96.08007327
C BAKU= 982 ppm

C. Baku (x) Abs. Baku (y) intercept= -0.36098

9.82 0.3605 SLOPE= 0.063285
14.73 0.5753 R= 0.951831 Kurva Regresi Bak
19.64 0.7738
Konsentrasi vs. Absor
24.55 0.9966
29.46 1.7035 1.8
1.6
1.4 f(x) = 0.0632851323828921 x − 0.36
1.2 R² = 0.905981379489884 0

Absorbansi
1 0.7738
0.8 0.5753
0.6
0.3605
0.4
0.2
0
5 10 15 20
Konsentrasi (ppm)
Kurva Regresi Baku
entrasi vs. Absorbansi
1.7035

= 0.0632851323828921 x − 0.36098
= 0.905981379489884 0.9966
0.7738
0.5753

15 20 25 30 35
Konsentrasi (ppm)