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MEGASYSTEM C

Department of Oncological and Reconstructive Surgery


CTO Florence Italy

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MEGASYSTEM C

Eclectic Device Different Clinical Conditions

tumor revision posttraumatic


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MEGASYSTEM C
Modularity
From a minimum of 5 cm
(revision surgery)

to the
“en bloc” knee
&
entire femur and tibia
(extensive tumor resection)
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MEGASYSTEM C
Modularity

1 cm

2cm

Accurate length adjustment 1cm by 1cm


( instead 2 by 2 )
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Further accomodation
with extension ring
in hip reconstructions
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MEGASYSTEM C
Complete Hip Joint System

- hip arthroplasty

conventional
snap fit
fully retentive

- bypolar cup

- saddle prosthesis
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MEGASYSTEM C
üAntiversion - adjustable at
surgery

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MEGASYSTEM C

New
endomodel
kinematic rotating hinge knee

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MEGASYSTEM C
Intraoperative changeable from rotational to total hinged
knee without removing stems or joint components

Assembly without
Component for rotation Component for extension between
and extension/flexion extension/flexion only femur and tibia

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MEGASYSTEM C

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MEGASYSTEM C

Same system : Conversion


3 Extensive revisions from arthroplasty
3 Resection arthroplasty to arthrodesis
3 Intercalary resections feasible at any time
3 Resection arthrodesis without stem removal

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MEGASYSTEM C
Stem fixation
Interchange ability

cemented cementless

Older pt. Younger pt.


Metastases Primary tumors
Osteoporotic Normal bone
Previous Rxth. None
Scheduled Rxth. None
Inadequate press fitt Adequate press fit

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MEGASYSTEM C

Cemented stem

Rough Collar Ring

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MEGASYSTEM C

enhanced scar tissue


prevents
polyethilene debris
migration
at the interface
stem / inner cortex

“purse string effect”

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MEGASYSTEM C
Cementless fixation

Rough titanium trunco conical flanged stems


(1 mm steps)
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MEGAPROSTHESIS C
Cementless fixation

Two antirotational pegs

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MEGASYSTEM C

The anchorage elements absorbs rotational forces


acting on the intramedulary stem anchorage. This
assures a bone-safe transmission between the
anchorage of the prosthesis and the bone

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MEGASYSTEM C

short cone
connection

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MEGASYSTEM C

Implant Flexibility
Conventional
megaprosthesis

Composite
allograft- prosthesis

Ibrid solutions
“encased grafts”

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MEGASYSTEM C

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MEGASYSTEM C

Implant Flexibility
Conventional
megaprosthesis

Composite
allograft- prosthesis

Ibrid solutions
“encased grafts”

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Rationale for alloprosthesis

üThe allograft allows a


normal distribution of
forces from implant to
host bone when union
has been achieved

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Alloprostheses vs Megaprostheses:
Outcome (10 years survival)

Alloprosthesis Megaprosthesis

Anract 77 none
Zehr 76 58
Capanna 85 83
Robb -- 63
Horowitz -- 67
Urwin -- 94

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Alloprostheses vs Megaprostheses:
Functional Results

Alloprosthesis Megaprosthesis

score limp can score limp can

Zehr 87 64 43 80 90 60

Anract 83 52 10 75 75 35

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MEGASYSTEM C

Implant Flexibility
Conventional
megaprosthesis

Composite
allograft- prosthesis

Ibrid solutions
“encased grafts”

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Rationale for alloprosthesis
Reattachment of bone and muscles is feasable and effective

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MEGASYSTEM C

osteosarcoma
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MEGASYSTEM C

osteosarcoma
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allograft

conventional

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MEGASYSTEM C : “conventional” tibia

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MEGASYSTEM C : “conventional” tibia

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MEGASYSTEM C : tibial “ encased graft ”

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Chondrosarcoma involving the entire tibia
with pathological fracture & closed nail fixation

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Osteoarticular
with
capsular repair
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5 years
follow up
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MEGASYSTEM C : knee “ ibrid” implant

Recurrent
G. C. T.
extensively
involving
the knee joint

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MEGASYSTEM C : knee “ ibrid” implant

Recurrent
G. C. T.
extensively
involving
the knee joint

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SERIES OF PATIENTS
Total 297 cases
Department of Orthopaedics, Florence, Italy
from june 2001 to july 2007
213 cases
University of Innsbruck, Austria
from maj 2002 to july 2007
60 cases
University of Hamburg, Germany
24 cases
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SERIES OF PATIENTS
297 cases
RECONSTRUCTION TYPE CASES

Proximal femur 130 (44%)

Distal femur 108 (36%)

Total femur 35 (12%)

Proximal tibia (sept. 2005) 10 (3.2%)

A-P composite of the knee 8 (3%)

Knee arthrodesis 5 (1.5%)

Intercalary resection of the femur 1 (0.3%)


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COMPLICATIONS
297 cases
34 cases (11.4%)
Type Florence Innsbruck Hamburg Tot.

Infection 14 1 2 17 (5.7%)
Mechanical 6 1 - 7 (2.3%)
failure
Dislocation 3 - 1 4 (1.3%)
Loosening 2 1 - 3 (1%)
Shaft perforation - 2 - 2 (0.6%)
Prosthetic 1 - - 1 (0.3%)
disconnection
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PROSTHETIC
COMPLICATIONS
17 out of 297 cases ( 6 %)
Type Florence Innsbruck Hamburg Tot.
Cone breakage 6 1 - 7 (2.3%)
Hip dislocation 3 - 1 4 (1.3%)
Stem loosening 2 1 - 3 (1%)
Shaft perforation - 2 - 2 (0.6%)
Cone 1 - - 1 (0.3%)
disconnection

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Mechanical failure
Florence experience

Total # %
213 pts 6 2.8%
493 cones 8 1.6%

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Further recent improvements

Modification on
cone
slope obliquity
shifting
stress
distribution
more at its basis
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Mechanical failure
Personal experience

Total # %
Before 150 pts 5 3.3
322 cones 7 2.1

Total # %
After 63 pts 1 1.5
171 cones 1 0.6
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Further recent improvements

Transfixing screws
for cone stability
were found
prudential
excessive
tools

Elimination of any stress riser or week point


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Further recent improvements

• Full thickness
cone
with total contact
• Removal of
transfixing screws

To avoid any stress riser or week point


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Further recent improvements :
biomechanical tests
Disassembling
forces :
6500 N without screw
8000 N with screw

Very safe locking


device
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Further recent improvements :
biomechanical tests
Small screw gripping
in a notch of the
collar

very effective
locking device
(up to 8000 N )
in a safe area
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Further recent improvements :
biomechanical tests
3 points bending stresses :
3500 N 10 Hz 10,000,000 cycles

No failure
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ALLOGRAFT COMPLICATIONS

TYPE NUMBER EFFECT


PARTIAL 1 CASE NO INFLUENCE ON
RESORPTION & FUNCTIONAL
FRACTURE (PROX FEM) OUTCOME
PARTIAL REMOVAL AFTER 4
1 CASE YEARS REVISION
RESORPTION FOR COTYLOIDITIS
POST-TRAUMATIC
EXTENSOR
1 CASE EXTENSOR LAG
APPARATUS
ELONGATION
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PRE RESORPTION & FRACTURE

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POST RESORPTION
&
FRACTURE

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ALLOGRAFT COMPLICATIONS

TYPE NUMBER EFFECT


PARTIAL 1 CASE NO INFLUENCE ON
RESORPTION & FUNCTIONAL
FRACTURE (PROX FEM) OUTCOME
REMOVAL AFTER 4
PARTIAL
1 CASE YEARS REVISION
RESORPTION
FOR COTYLOIDITIS
POST-TRAUMATIC
EXTENSOR
1 CASE EXTENSOR LAG
APPARATUS
ELONGATION
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