MARY ANN TIMMERMAN, MS, MSBS

Home: 855 Sandlake Drive ~ Unit B ~ Mount Pleasant, SC 29464

Work: CVAMC ~ 109 Bee Street (116) ~ Charleston, SC 29401
Home (843) 216-0422 ~ Work (843) 789-7502 ~ mteaa2f6@westpost.net
QUALIFICATIONS PROFILE
Clinical Trial Management ~ Biomedical Science ~ Epidemiology ~ Grant Writing &
Administration
Highly astute, versatile, and diligent professional offering a flexible backgrou
nd in clinical trial management, project coordination, statistical analysis, and
grant writing/administration among all disease processes. Strong experience at
the Medical University of South Carolina (MUSC), including successfully securing
an independent NIH-NIAAA F31 grant. Concurrently managed all aspects of four ph
armacological clinical trials. Gained significant experience in studying disease
in Oncology, Diabetes, Cardiology, etc through real-life clinical vinnettes in
biomedical science. Praised for insight and resourcefullness in reviewing and im
plementing research protocols. Recipient of the prestigious MUSC Presidential Sc
holar Award. CRA designation pending. Team-oriented work ethic with excellent mu
ltitasking and organizational abilities combined with strong interpersonal and c
ommunication skills. Available for travel and relocation. Additional expertise i
ncludes:
a PHARMACOLOGICAL CLINICAL TRIALS
a STATISTICAL ANALYSIS
a DATABASE DESIGN & MANAGEMENT
a EDC SYSTEMS
a RESEARCH GRANTS & PROPOSALS
a SUBJECT RECRUITMENT & RETENTION
a PROGRAM DEVELOPMENT & MANAGEMENT
a REGULATORY AFFAIRS & MANAGEMENT
EDUCATION
MEDICAL UNIVERSITY OF SOUTH CAROLINA, Charleston, SC
MASTER OF SCIENCE, BIOMEDICAL SCIENCE, Focus in Epidemiology/Research Administra
tion, 12/2009
VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY, Blacksburg, VA
MASTER OF SCIENCE, EXPERIMENTAL PSYCHOLOGY, Focus in Substance Abuse Research, 5
/1999
LANDER UNIVERSITY, Greenwood, SC
BACHELOR OF SCIENCE - PSYCHOLOGY, Focus in Psychological Research, Magna cum Lau
de, 5/1997
PIEDMONT TECHNICAL COLLEGE, Greenwood, SC
ASSOCIATE OF SCIENCE, HUMAN SERVICES, 12/1994
ASSOCIATE OF SCIENCE, BUSINESS AND SOCIAL MARKETING, 5/1985
AWARDS & GRANTS
a NIH-NIAAA F31 Grant, 2005 - 2007
a Presidential Scholar, Medical University of South Carolina, 2005
a Grantee, Anheuser-Busch Corporation, Virgonia Tech., 1998-1999
a Psi Chi Research Award, 1997
a Outstanding Research Student Award, Lander University, Behavioral Science Divi
sion, 1997
a 1st Place, South Carolina Psychological Association Psychology Bowl, 1996
PROFESSIONAL EXPERIENCE
CHARLESTON RESEARCH INSTITUTE/CVAMC/MUSC, Charleston, SC (2007 a" Present)
SENIOR RESEARCH COORDINATOR
Oversee numerous federal, VA Merit, and industry-sponsored pharmacological trial
s, including regulatory and budget management. Hire and supervise research assis
tants/coordinators. Devise recruitment and retention strategies, ensure protecti
on of human subjects, formulate study procedures, and serve as a liaison to mult
iple sites. Perform statistical analysis, and coordinate EDC systems. Prepare gr
ant submissions, adverse events reporting, manuscripts, and good clinical practi
ces. Key Achievements:
a Pursuing CRA designation, a national accreditation in research administration
DEPARTMENT OF PSYCHIATRY AND BEHAVIORAL SCIENCE, MUSC, Charleston, SC (2002 a" 2
005)
PROJECT COORDINATOR II
Implemented NIH-funded and industry research studies on PTSD and substance abuse
. Delivered key contributions as a grant writing assistant and primary statistic
al analyst for Kathleen T. Brady, MD, PhD., PI, primary coordinator at GCRC stud
ies on stress response hormones in PTSD.
DEPARTMENT OF PSYCHIATRY AND BEHAVIORAL SCIENCE, MUSC, Charleston, SC (2000 a" 2
002)
STATISTICAL RESEARCH ANALYST III
Spearheaded database design and management. Served as a statistical analyst. Orc
hestrated research management as well as TELEFORM design and management. Oversee
r of clinical trial on Naltrexone in alcoholics at Dorchester alcohol and drug c
ommission in Summerville, SC.
CENTER FOR DRUG AND ALCOHOL PROGRAMS, MUSC, Charleston, SC (1999 a" 2000)
MENTAL HEALTH TECHNICIAN
Conceptualized, developed, and executed an inpatient reward-based substance abus
e program. Delivered substance abuse/psychological counseling, including functio
n as a group facilitator.
ADDITIONAL EXPERIENCE
DEPARTMENT OF MEDICINE, DIVISION OF BIOMEDICAL SCIENCE, MUSC, Charleston, SC
NIH/NIAAA F31 GRANT RECIPIENT, 2005-2007
Principle Investigator: aSocial Capital and Alcohol-related mortalities, ER admi
ssions, and treatment utilization among the counties of South Carolinaa
a Drove research grant from NIH submission to closure which resulted in the deve
lopment of one of the most extensive alcohol-related databases in the state. Res
ulted in three manuscripts for journal submission.
CENTER FOR APPLIED BEHAVIOR SYSTEMS, VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIV
ERSITY, Blacksburg, VA
GRADUATE RESEARCH ASSISTANT, 1998-1999
Project Director
a Garnered an Anheuser-Busch grant to develop an alcohol intervention/prevention
program featuring a city-wide designated driver program for college students.
a Utilized SPSS, and performed SAS data analysis, coordinated large-scale databa
ses (Access, Excel,etc.).
a Supervised over 20 research assistants.
a Authored and published a masteras thesis detailing findings in the Journal of
Safety Research.
a Taught a sophomore-level Research Methodology course.
DEPARTMENT OF PSYCHOLOGY, VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY
GRADUATE RESEARCH ASSISTANT, 8/1997-12/1997, Visual Perception Study
Secondary Investigator working under Principal Investigator: Dr. Albert Prestrud
e / Specialty: Sensory Perception.
a Contributed to a study on the aesthetic aspects of particular streams in easte
rn Tennessee under funding from Champion Paper.
a Organized field research, performed data analysis, and managed database.
AFFILIATIONS & INVOLVEMENT
a AMERICAN STATISTICAL ASSOCIATION, 2002-PRESENT
a SOCIETY FOR EPIDEMIOLOGICAL RESEARCH, 2003-PRESENT
a RESEARCH SOCIETY ON ALCOHOLISM, 2003-PRESENT
a PSI CHI NATIONAL HONOR SOCIETY FOR PSYCHOLOGY, 1995 -1997
a ALPHA CHI NATIONAL HONOR SOCIETY, 1996-1997
a LANDER UNIVERSITY PSYCHOLOGY CLUB, 1996-1997
a PSI BETA NATIONAL HONOR SOCIETY FOR PSYCHOLOGY, 1993-1995
COMMUNITY ACTIVITIES & VOLUNTEERISM
a Volunteer, Sanders Clyde Elementary Lunch Buddy Program, 2004-2007
a President, Lander University Psychology Club, 1996-1997
a Vice President, Psi Beta National Honor Society for Psychology, 1993-1995
a Volunteer, Hospice Day Camp for Children, Greenwood, SC, 1996-1997
a Volunteer, Leathe Correctional Facility for Women, Greenwood, SC, 1993-1997
a Group Facilitator, ScIP (School Intervention Program), Calhoun Falls High Scho
ol, 1994-1997
a Board Member, Greenwood County Mental Health Association, 1994-1997

SELECTED PUBLICATIONS & PRESENTATIONS

a Verduin M.L., Carter, R.E., Brady, K.T., Myrick, H., & Timmerman, M.A., (2005)
. Health service utilization in comorbid bipolar and substance abuse disorders:
a retrospective chart review. Psychiatric Services Apr; 56(4):475-80.
a McRae, AL, Brady KT, Mellman TA, Sonne SC, Killeen TK, Timmerman MA, & Bayles-
Dazet W. (2004). Comparison of nefazodone and sertraline for the treatment of po
sttraumatic stress disorder. Depression and Anxiety, 19(3): 190-6.
a Upadhyaya HP, Santa Ana E, Saladin ME, Spratt EG, Timmerman MA, Brady KT, McRa
e AL, & Waldrop A. (2004). Trauma-specific factors and stress responding in como
rbid PTSD and substance use disorder. Poster presentation: American Academy of C
hild and Adolescent Psychiatry: Washington, DC.
MARY ANN TIMMERMAN, MS, MSBS
Page 4 of 5
a Santa Ana, E.L., Saladin, M., Spratt, E., Brady, K.T., & Timmerman, M.A., (200
4). Physiological responses to stress in comorbid PTSD & alcohol-dependence. Pap
er presentation: College of Problems in Drug Dependence: San Juan, Puerto Rico.
a Timmerman, M.A., Geller, E.S., Glindemann, K.E., Fortnier, A. (2003). Do the d
esignated drivers of college students stay sober? Journal of Safety Research 34(
2):127-33. [Masteras Thesis Published]
a Back, S.E., McRae, A.L., Brady, K.T., Anton, R.F., Randall, C. & Timmerman, M.
A. (2002). Relationship between stress reactivity and subsequent alcohol use. Po
ster session: College on Problems of Drug Dependence.
a Timmerman, M.A., Glindemann, K., Carter, N., & Geller, E.S. (1999). An evaluat
ion of designated driver use: Does it lead to increased levels of passenger into
xication? Paper presented at the Association of Applied Behavior Analysis Confer
ence [May 1999]. Chicago, IL.
a Timmerman, M.A., Grossman, B.M., Lea, B.N., & Booth, S. (1999). A field study
of factors influencing the use of designated drivers in a community setting. Pos
ter presented at the Association of Applied Behavior Analysis Conference [May 19
99]. Chicago, IL.
a Glindemann, K.E., Timmerman, M.A., & Clarke, S.W. (1998). Effects of peer infl
uence and history of alcohol consumption on perceptions of normative alcohol use
. Published in Advances and Challenges in Prevention Science for the 21st Centur
y: Proceedings of the 6th Annual Meeting of the Society for Prevention Research.
a Timmerman, M.A., (1997). Academic achievement, locus of control, & the imposto
r phenomenon. Senior Honors Thesis, May 1997.

CURRENT GRANT EXPERIENCE

LEAD RESEARCH COORDINATOR
VA/DOD (INVESTIGATOR INITIATED)
A Randomized, Placebo-Controlled Trial of the Dopamine--Hydroxylase Inhibitor, N
epicastat, for the Treatment of PTSD in OIF/OEF Veterans.
Goals: Proposed a multi-site, randomized, double-blind, placebo-controlled pilot
clinical trial of the dopamine- -hydroxylase (DBH) inhibitor, nepicastat, for t
he treatment of PTSD in outpatients who have previously served in a combat zone
during Operation Iraqi Freedom & Operation Enduring Freedom.
REPLIGEN CORPORATION
RG2417-03
A Phase II Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose Study to
Assess the Safety, Tolerability and Efficacy of RG2417 (Uridine) in the Treatmen
t of Bipolar I Depression.
OTSUKA PHARMACEUTICALS
I. A 38-week, Multicenter, Randomized, Double-blind, Active-controlled Study to
Evaluate the Efficacy, Safety, and Tolerability of an Intramuscular Depot Formul
ation of Aripiprazole (OPC-14597) as Maintenance Treatment in Patients with Schi
zophrenia.
II. A 52-week, Multicenter, Open-label Study to Evaluate the Effectiveness of Ar
ipiprazole Intramuscular Depot as Maintenance Treatment in Patients with Schizop
hrenia.
STATISTICAL ANALYST
U.S. DEPARTMENT OF VETERANS AFFAIRS, ORD, CLINICAL SCIENCE SERVICE
CLINICAL RESEARCH MERIT
A Placebo-Controlled Trial of Adjunctive Quetiapine for Refractory PTSD.
Goals: Focused on improving prior methodologies by enrolling patients deemed ref
ractory to paroxetine after an initial 8-week prospective open-label trial. Obje
ctive is to evaluate the efficacy of this combination strategy on core PTSD symp
toms, associated symptoms and
comorbidities, sleep disturbances, cognitive functioning, quality of life, and o
verall level of functioning.
SUB-INVESTIGATOR
PFIZER PHARMACEUTICALS
Ziprasidone Augmentation for Treatment-Resistant PTSD in Veterans of the Iraq-Ir
an Wars.
Goals: A two-phase study which prospectively identified veteransa refractory to
8 weeks of treatment with an antidepressant which is FDA-approved for the treatm
ent of DSM-IV PTSD in addition to augmenting treatment with ziprasidone or place
bo for an additional 8 weeks.

REFERENCES
a KATHLEEN T. BRADY, MD, PhD a" Distinguished Professor of Psychiatry; Director,
Clinical Neuroscience Division. Associate Dean for Clinical Research; Director,
General Clinical Research Center at MUSC. Contact Information: 792-5215: bradyk
@musc.edu
a ROBERT S. WOOLSON, PhD a"Professor Emeritus of Biostatistics and Epidemiology,
Department of Medicine, MUSC. Contact Information: 876-1135: woolson@musc.edu.
Adjunct Professor of Biostatistics & Bioinformatics and Senior Statistical Consu
ltant for Center for Health Services Research and Development for Primary Care,
Duke University a" skip.woolson@duke.edu.
a KATHRYN M. MAGRUDER, MPH, PhD. a" Chair of Institutional Review Board I, Profe
ssor, Department of Psychiatry & Behavioral Sciences, Military Science Division.
Department of Medicine, Division of Biostatistics & Epidemiology, MUSC. Contact
Information: 843.789.7280 or magrudkm@musc.edu