New World Medical, Inc.

(NWMI) is a high tech medical device company whose goal is to help humanity lead a better life through improved technology and innovation. Presently NWMIs focus is in the areas of ophthalmology, neuro-surgery, urology and rapid medical diagnostic tests such as, the detection of HIV. The Ahmed Glaucoma Valve has been successfully demonstrated to work in all types of glaucoma cases, particularly neovascular, congenital and uvietic glaucoma. New World Medical, Inc. manufactures and markets its own products. In the U.S. domestic market NWMI distributes its products through a team of sales representatives. In the international market the company has more than 35 exclusive distributors around the world. Along with its own products, NWMI is licensed as a tissue bank, selling human tissue such as sclera and pericardium. The active R & D division of NWMI is intensely involved in developing new products through collaborations with a number of renowned medical universities and individual doctors, in the U.S. and abroad. These partnerships allow NWMI to develop products through a rst hand involvement in the medical device industry. Omar Ahmed has recently joined as Vice President, Director and COO of NWMI. New World Medical Inc. was founded by Dr. A. Mateen Ahmed. Dr. Ahmed is also the President, CEO and the Chairman of the Board of Directors for the company. The vision of Dr. Ahmed and NWMI is to help the lives of people around the world. This has earned the company many accolades, including the Have a Heart, International Goodwill and Understanding Award given by Soroptimist International.

Mechanics of the Ahmed Glaucoma Valve

Venturi-Flo
The Venturi Effect To reduce internal friction within the valve system, the Ahmed Glaucoma Valve (AGV) utilizes a specially designed, tapered trapezoidal chamber to create a Venturi effect to help aqueous ow through the device. As demonstrated by Bernoullis equation of hydrodynamic principle, the inlet velocity of aqueous entering the larger port of the Venturi chamber increases signicantly as it exits the smaller outlet port of the tapered chamber. In an AGV this increased exit velocity greatly helps in evacuating aqueous from the valve, thereby helping to reduce valve friction. Fluid owing into section 1 = Fluid owing out of section 2

Section 1 P1 Section 2 P2

V1 V2

Non-Obstructive, Self-Regulating Mechanism The Ahmed Glaucoma Valve has no obstruction in its path of uid ow. For the ow to be non-obstructive, a particle large enough to pass through the lumen of the tube, will easily pass through a much larger opening of the Venturi-Flow chamber. The elastic membranes help to regulate uid ow at all times, consistently by changing their shape. The tension on these membranes is responsible for reducing hypotony.

Product Index

Model

Product

FP7 ................... Ahmed Glaucoma Valve Flexible Plate S2..................... Ahmed Glaucoma Valve FP8 ................... Ahmed Glaucoma Valve Flexible Plate (Pediatric Size) S3..................... Ahmed Glaucoma Valve (Pediatric Size) FX1 ................... Ahmed Glaucoma Valve Flexible Bi-Plate B1 .................... Ahmed Glaucoma Valve Bi-Plate FX4 ................... Non-Valved Flexible Plate B4 .................... Non-Valved Plate PC..................... Pars Plana Clip TE ..................... Tube Extender

Product Index

Model

Product

PC7................... Ahmed Glaucoma Valve Flexible Plate FP7 with Pars Plana Clip PC8................... Ahmed Glaucoma Valve Flexible Plate FP8 with Pars Plana Clip PS2 ................... Ahmed Glaucoma Valve S2 with Pars Plana Clip PS3 ................... Ahmed Glaucoma Valve S3 with Pars Plana Clip TI ...................... Tube Inserter

Tissue TSH ................... Sclera Hydrated TPH ................... Pericardium Hydrated TPD ................... Pericardium Freeze-Dried

FP7

Model FP7
Made of medical grade silicone

Ahmed Glaucoma Valve Flexible Plate

Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Tapered prole for easy insertion Silicone plate Aqueous percolation holes Thinner Plate Ordering Info:
Model: FP7 - Ahmed Glaucoma Valve

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Silicone Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Thickness: Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 0.9 13.00 16.00 184.00 25.00 0.305 0.635 mm mm mm mm2 mm mm mm

FP7 Surgical Procedure

Step 1 Step 2 Step 3 Step 4

FP7

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.
Step 5 Step 6 Step 7 Step 8

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

S2

Model S2

Ahmed Glaucoma Valve

Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Eliminates drainage tube ligature sutures, rip-chord sutures, occluding sutures

Ordering Info:
Model: S2 - Ahmed Glaucoma Valve

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Polypropylene Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Thickness: Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 1.9 13.00 16.00 184.00 25.00 0.305 0.635 mm mm mm mm2 mm mm mm

S2 Surgical Procedure
Step 1 Step 2 Step 3 Step 4

S2

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.
Step 5 Step 6 Step 7 Step 8

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

FP8

Model FP8
Made of medical grade silicone

Ahmed Glaucoma Valve Flexible Plate

Used for Pediatrics or small globes Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Eliminates drainage tube ligature sutures, rip-chord sutures, occluding sutures Thinner Plate

Ordering Info:
Model: FP8 - Ahmed Glaucoma Valve Small

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Silicone Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 9.60 10.00 96.00 25.00 0.305 0.635 mm mm mm2 mm mm mm

FP8 Surgical Procedure

Step 1 Step 2 Step 3 Step 4

FP8

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.
Step 5 Step 6 Step 7 Step 8

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

S3

Model S3

Ahmed Glaucoma Valve

Used for Pediatrics or small globes Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Eliminates drainage tube ligature sutures, rip-chord sutures, occluding sutures

Ordering Info:
Model: S3 - Ahmed Glaucoma Valve Small

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Polypropylene Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 9.60 10.00 96.00 25.00 0.305 0.635 mm mm mm2 mm mm mm

S3 Surgical Procedure
Step 1 Step 2 Step 3 Step 4

S3

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.
Step 5 Step 6 Step 7 Step 8

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

FX1

Model FX1
Made of medical grade silicone

Ahmed Glaucoma Valve Flexible Bi-Plate

Attachable on either right or left side Bi-Plate design allows for greater aqueous drainage Valve and Bi-Plate surface area: 364mm2 Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Eliminates drainage tube ligature sutures, rip-chord sutures, occluding sutures Ordering Info:
Model: FX1 (Model FP7 with non-valved Plate)

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Silicone Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Width: Length: Tube Length: Surface Area: Tube Inner Diameter: Tube Outer Diameter: Valved Plate 13.00 mm 16.00 mm 25.00 mm 184.00 mm2 0.305 mm 0.635 mm Non-Valved Plate 12.20 mm 14.80 mm 25.00 mm 180.00 mm2 0.305 mm 0.635 mm

B1

Model B1

Ahmed Glaucoma Valve Bi-Plate Attachable on either right or left side Bi-Plate design allows for greater aqueous drainage Valve and Bi-Plate surface area: 364mm2 Immediate reduction of intraocular pressure Unique, non-obstructive valve system to prevent excessive drainage, chamber collapse Implanted in a true, single-stage procedure Eliminates drainage tube ligature sutures, rip-chord sutures, occluding sutures Ordering Info:
Model: B1 (Model S2 with non-valved Plate)

Materials:
Valved Plate Body: Drainage Tube: Valve: Medical Grade Polypropylene Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane

Nominal Specs:
Width: Length: Tube Length: Surface Area: Tube Inner Diameter: Tube Outer Diameter: Valved Plate 13.00 mm 16.00 mm 25.00 mm 184.00 mm2 0.305 mm 0.635 mm Non-Valved Plate 12.20 mm 14.80 mm 25.00 mm 180.00 mm2 0.305 mm 0.635 mm

FX4

End xed to the Valved Plate

Model FX4
Flexible Non-Valved Plate Made of medical grade silicone Used with existing implants Can be inserted in existing bleb Attachable on either right or left side Increases surface area of existing implant Can be placed over or under the muscle Easily sutured on sclera

Non-Valved Plate

Ordering Info:
Model: FX4 - Non-valved Flexible Plate

Materials:
Non-Valved Plate Body: Drainage Tube: Medical Grade Silicone Medical Grade Silicone

Nominal Specs:
Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 12.20 14.80 180.00 25.00 0.305 0.635 mm mm mm2 mm mm mm

FX4 Surgical Procedure

Step 1 Step 2 Step 3 Step 4

FX4

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.

Step 5

Step 6

Step 7

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

B4

End xed to the Valved Plate

Model B4
Non-Valved Plate Used with existing implants Can be inserted in existing bleb Attachable on either right or left side Increases surface area of existing implant Can be placed over or under the muscle Easily sutured on sclera

Non-Valved Plate

Ordering Info:
Model: B4 - Non-valved Plate

Materials:
Non-Valved Plate Body: Drainage Tube: Medical Grade Polypropylene Medical Grade Silicone

Nominal Specs:
Width: Length: Surface Area: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 12.20 14.80 180.00 25.00 0.305 0.635 mm mm mm2 mm mm mm

B4 Surgical Procedure
Step 1 Step 2 Step 3 Step 4

B4

The steps illustrated here are intended as a guideline only, and do not represent recommended treatment for any particular patient. The use of any specic surgical technique or maneuver is at the sole discretion of the surgeon.

Step 5

Step 6

Step 7

Surgeons should be familiar with the use of glaucoma drainage devices and post-operative care considerations before implanting any drainage device. Reference papers and surgical video tapes are available upon request.

PC

Model PC
Pars Plana Clip Provides for valve tube insertion into the pars plana Fully adjustable along length of tube Does not compromise integrity of valve tube Smooth curvature eliminates kinking Can be used with any drainage device Easily sutured on sclera
Int oP te os rio r a Ch mb er
To Valve

Ordering Info:
Model: PC - Pars Plana Clip

Materials:
Clip: Medical Grade Silicone

Nominal Specs:
Width: Length: Tube Inner Dia.: Positioning Holes Dia.: 4.60 5.80 0.635 0.025 mm mm mm mm

TE

Model TE
Tube Extender
e Tub fro

he mt

v Val

Provides extra tube length for necessary cases Provides leak-proof junction between tubes Helpful in cases where drainage tube is cut too short Can be used with any drainage device Easily sutured on sclera

Ordering Info:
Model: TE - Tube Extender

Materials:
Junction: Drainage Tube: Medical Grade Silicone Medical Grade Silicone

Nominal Specs:
Width: Length: Height: Tube Length: Tube Inner Diameter: Tube Outer Diameter: 2 Positioning Holes: 3.050 4.750 1.140 24.13 0.305 0.635 0.025 mm mm mm mm mm mm in dia.

PC7 & PC8

Models PC7 & PC8

Made of medical grade silicone Model FP7 and FP8 valves already integrated with Pars Plana Clip Reduces preptime for posterior chamber insertions Clip is fully adjustable along tube length Easily sutured on sclera Clip allows the tube not to kink

Ahmed Glaucoma Flexible Plate with Pars Plana Clip

Model PC7

Model PC8

Ordering Info:
Model: PC7 (Model FP7 with Pars Plana Clip) Model: PC8 (Model FP8 with Pars Plana Clip)

Materials:
Valved Plate Body: Drainage Tube: Valve: Clip: Medical Grade Silicone Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane Medical Grade Silicone

PS2 & PS3

Models PS2 & PS3

Ahmed Glaucoma Valve with Pars Plana Clip Model PS2 and PS3 valves already integrated with Pars Plana Clip Reduces preptime for posterior chamber insertions Clip is fully adjustable along tube length Easily sutured on sclera Clip allows the tube not to kink Model PS3

Model PS2

Ordering Info:
Model: PS2 (Model S2 with Pars Plana Clip) Model: PS3 (Model S3 with Pars Plana Clip)

Materials:
Valved Plate Body: Drainage Tube: Valve: Clip: Medical Grade Polypropylene Medical Grade Silicone Medical Grade Silicone, Elastomer Membrane Medical Grade Silicone

TI

Model TI
Tube Inserter Notched tip secures valve tube Provides rigidity to valve tube for easy insertion into anterior or posterior chamber Stainless steel Serrated grip Shorter tip helps to provide better view through microscope Very inexpensive Re-usable Can be used with any drainage device

Ordering Info:
Model: TI - Tube Inserter

TSH / TPH / TPD

Human Allograft Tissue

Sclera & Pericardium Biocompatible human tissue Gamma sterilized 2.5 years shelf life Nominal thickness 0.5 mm Pretrimmed for ease of placement Available Freeze Dried or Hydrated for immediate use Cost effective Available as full thickness sclera or pericardium Available in all sizes Can be used as occular tissue for other cosmetic uses Used for leaking blebs

Ordering Info:
TSH (Human Sclera) TPH (Hydrated Pericardium) TPD (Freeze Dried Pericardium)

Comparison of Ahmed Glaucoma Valve with Other Drainage Devices

Product
Ahmed Glaucoma Valve

Drainage Device
Model S3 Model S2 Bi-Plate BG103-250 BG-101-350 BG103-425 Single Plate Double Plate

Surface Area
96mm2 184mm2 364mm2 250mm2 350mm2 425mm2 135mm2 270mm2

Valved/Non-Valved
Valved Valved Valved Non-Valved Non-Valved Non-Valved Non-Valved Non-Valved

Baerveldt

Molteno

Type
Success Rate (Lowering of IOP) Visual Acuity (Improved or within one Snellen Line) Hypotony (Occurrence) Success Rate with Corneal Grafts

Ahmed Glaucoma Valve

95%

Baerveldt
72%

Molteno
60%

82%

62%

70%

8%

26%

14.60%

84.10%

54%

76%

Coleman AL, Mondino BJ, Wilson MR, Casey R. Clinical Experience with the Ahmed Glaucoma Valve Implant in Eye with Prior or Concurrent Penetrating Keratoplasties. American Journal of Ophthalmology 1997; 123:54-61 Hodkin MJ, Goldblatt WS, Burgoyne CF, Ball SF. Early Clinical Experience with the Baerveldt Implant in Complicated Glaucomas. American Journal of Ophthalmology 1995; 120:32-40 Huang MC, Netland PA, Coleman AL, Siegner SW, et al. Intermediate-term Clinical Experience with the Ahmed Glaucoma Valve Implant. American Journal of Ophthalmology 1999; 127:27-33 Lloyd MA, Baerveldt G, Fellenbaum PS, Sidoti PA, Minckler DS, et al. Intermediate Term Results of a Randomized Clinical Trial of the 350 versus the 500mm Baerveldt Implant. Ophthalmology 1994; 101:1456-1464 McDonnell PJ, Robin JB, Schanzlin DJ, Minckler D, et al. Molteno Implant for Control of Glaucoma in Eyes After Penetrating Keratoplasty. Ophthalmology 1988; 95:364-369 Melmed S. Cahane M, Gutman I, Blumenthal M. Postoperative Complications After Molteno Implant Surgery. American Journal of Ophthalmology 1991; 1:319-322 Mermoud A. Salmon JF, Straker C. Murray AND. Use of the Single Plate Molteno Implant in Refractory Glaucoma. Ophthalmologica 1992; 205:113-120