Anda di halaman 1dari 9

cobas 6000 analyzer series

Flexibility you can build on The cobas 6000 analyzer series offers tailor-made solutions for mediumto-large workload laboratories. Flexible combinations of clinical chemistry (cobas c 501 module) and immunochemistry testing (cobas e 601 module) modules are available. Flexible consolidation

Ready for the unexpected


Consolidates up to 171 tests on one system from a menu of over 200 available tests Combines STAT with routine testing without disruption Seamlessly integrates pre- and post-analytical solutions Can expand existing system configurations on-site

Unique reagent concept

Convenient handling, cost-effective operation


One grip handling without preparation for most reagents On the fly loading of chemistry reagents during operation Interchangeable with other cobas Serum Work Area systems Economic usage with high stabilities and convenient kit sizes

Superior analytical standards

Right first time

State-of-the-art immunoassay testing using ECL technology Reference-traceable results with minimal lot-to-lot variance High quality results obtained by ensuring sample and result integrity (e.g. test-specific serum indices, disposable immunoassay tips and cups, and clot detection) Innovative tests on a standardized, automated platform Results standardized to other cobas Serum Work Area systems

Proven system performance

Maximum system uptime


Partnership with Hitachi: 30 years as a total solution provider Over 4000 systems and over 6000 modules installed in over 40 countries Greatly reduced and automated maintenance, now improved with software version 04-02 Over 99% observed system uptime*

Seamless implementation

With you every step of the way


Tailor-made solutions through work-process consultations Optimum lab design within challenging environmental constraints Experienced project management for seamless implementation Timely and efficient routine service and support

*Source: Internal Roche US service reports

Technical Specifications: 2nd Generation SWA: modular, analytical system platform, consolidated work area for Clinical Chemistry and Immunology, expandable and re-configurable on site PC, monitor, keyboard, printer, Control Unit: etc. on an ergonomic stand Sample input/output, sample Core Unit: transport by Intelligent Process Management Analytical 2 analytical modules modules: cobas c 501 hotometric measuring unit module: (incl. ISE) cobas e 601 ECL technology measuring

System

System components

Type of modules

Number of module combinations

module: unit 7 module combinations Up to 3 modules in one core unit cobas c 501 1 to 2 modules modules: cobas e 601 1 to 2 modules modules: 2 to 3 modules (only 2 cobas c 501 and units of one module cobas e 601 type modules: for SWA combinations possible)

Sample throughput

Test throughput(theoretical max)

Up to 120 racks/hr or 600 samples/hr 170 up to 2170 - overall tests/hr 1000 up to 2000 - with cobas c 501 modules tests/hr 170 up to 340 - with cobas e 601 modules tests/hr 1170 up to 2170 - with cobas c 501 and tests/hr cobas e 601 modules Up to 151 channels, in total

Number of 63 channels (including ISE, automatic setting) channels(reagent slots) on cobas c 501 module 25 channels on cobas e 601 module 191 parameters with photometric and HetIA modules Programmable parameters 117 photometric tests, 3 ISE tests, 8 formulas, 3 serum indices with photometric modules 60 heterogeneous tests with cobas e 601 modules Serum, Plasma, Urine, CSF Rack: 5 position rack, RD standard rack Rack Routine, STAT, Control, Calibrator, types: Re-run (manual), Wash Tray with 15 racks/75 samples, RD Tray: standard tray STAT STAT samples are processed with

Sample material

Core unit analytics

port: priority Primary 5 to 10 mL; 16 x 100, 16 x 75, 13 tubes: x 100, 13 x 75 mm Sample Sample container types 2.5 mL cup: 1.5 mL, (exception: cobas e 601 Micro cup: module) Sample volume 1 - 35 L Sample dilution 3 - 121 times, diluent > 100 L Available for cobas c 501 and cobas e 601 Sample clot detection module fiPrimary tubes: 700 L Minimum sample Sample cup: 100 L volume Micro cup (FBT):50 L Code 128; Codabar (NW 7); Interleaved 2 of Sample barcode types 5; Code 39 PC: Windows XP, Pentium IV processor, DVDRAM Monitor: 17 TFT touch screen colour monitor Keyboard 101 key enhanced, countryspecific Printer: optional PC stand: optional, ergonomic (UL, CE, GS, TV) cobas link data station RS 232 serial interface, bi-directional Interface to cobas link data station for cobas teleservice functionalities and automatic download 10.000 routine/STAT samples For photometric modules: 1 point, 1 point + prozone check, 2 point, 2 point kinetic, 2 point + prozone check, 3 point, 1 point + kinetics Rate A, Rate A + serum index, Rate A with blank, Rate B Via specified racks through the input buffer or STAT port Start-up, Re-calibration

Control unit

System interfaces Sample data base

Test methods

Calibrator/QC input Calibration methods

For photometric modules: Linear, non-linear multi-points, 2 point calibration, K-factor up to 100 different calibrators pre programmable Storage of up to 180 curves Preventive calibration of the stand-by cobas c and cobas e packs on cobas c 501: Two k-factor can be defined for different sample types For e- and photometric modules: Real-time QC, individual QC, cumulative QC Up to 100 controls pre programmable QC methods Preventive QC after calibration of the standby cassettes/rack packs Auto QC: QC without operator intervention (timer triggered) Automatic rerun and manual rerunAutomatic reflex is supported by the system, reflex request to be provided by PSM or LIS 230 Volts AC; 110 Volts AC, Power 2.4 kVA (for cobas c requirements: 501 and cobas e 601) Frequency: 50 Hz or 60 Hz +/- 0.5 % Bacteria free, deionised water Water: supply: resistance of < 1,0 S/cm Under routine conditions in Water average 15 L/hr, max. 30 L/hr consumption: (per module) Water 0.5 3.5 kg/cm3, (49 - 343 pressure: Kpa) Biohazards Separate container behind the waste: system L. concentrated Central drain port, diameter: Wall drain < 50 mm / 2 inches 100 mm waste: above the floor GS, CE, UL, C-UL Ambient temperature: 15 to 32 C / 59 to 90 F

Rerun/reflex function

Electrical requirements

Water/waste requirements

Regulatory requirements Operating conditions

Ambient humidity:

45 to 85 % (RH, without condensation) 1.5 kW (5400 kJ/hr for cobas Heat output: c 501, 4320 kJ/hr for cobas e 601) Noise output: < 68 dB 188 to 498 cm / 74 to 196 inches Core Unit: 69 cm / 27.2 inches, cobas c or cobas e module: 120 cm / 47.2 inches cobas c or cobas e module: 98 cm Depth: / 38.6 inches, Core unit: 104 cm / 41 inches Height: 130 cm / 51 inches Control Width: 80 cm / 31.5 inches, depth: unit: 80 cm / 31.5 inches 510 to 1230 kg / 1124 to 2711 lb 330 kg / 730 cobas c 501 module: lb 360 kg / 795 cobas e 601 module: lb 180 kg / 400 control unit, rack rotor): lb Width:

Physical dimensions

Weight

Substrates Albumin (BCP+BCG) Ammonia Bicarbonate Bilirubin-direct Bilirubin-total Calcium Cholesterol HDL Cholesterol LDL Cholesterol Creatinine enz. Creatinine Jaff Fructosamine Glucose Iron Lactate

cobas c 501 assay menu Enzymes ACP ALP ALT / GPT Amylase-tot. Amylasepancr. AST / GOT Cholinesterase Acetyl Cholinesterase Butyryl Cholinesterase Dibucain CK CK-MB GGT GLDH HBDH LDH

Proteins 1-Acid Glycoprotein a1-Antitrypsin a1-Microglobulin 2-Microglobulin Albumin (immuno.) APO A1 APO B ASLO C3c C4 Ceruloplasmin CRP CRP High Sensitivity Cystatin C Ferritin

Magnesium Phosphorus Total Protein Total Protein U / CSF Triglycerides Triglycerides GB UIBC Urea / BUN Uric Acid

Lipase

Electrolytes (ISE)
Chloride Potassium Sodium

Haptoglobin HbA1c (whole blood + hemolysate) Homocysteine 2 IgA IgG IgM Kappa Light chains Freelite Human Kappa Free2 Lambda Light chains Freelite Human Lambda Free2 Lipoprotein (a) Myoglobin Prealbumin RF Soluble Transferrin Receptor Transferrin Others D-Dimer Anti-Thrombin III TPLA-Trepanoma pallidum

Drugs of abuse (DAT) Amphetamines Barbiturates Benzodiazepines

Therapeutic drug monitoring (TDM) Acetaminophen Amikacin Carbamazepine

Cannabinoids Cyclosporine 1 Cocaine Digitoxin LSD Digoxin Ethanol Gentamicin Methadone Lidocaine 1 Methadone Methabolite Lithium (EDDP) Methaqualone MPA-T Opiates NAPA Oxycodone Phenobarbital Phencyclidine Phenytoin Propoxyphene Procainamide Quinidine Salicylate Theophylline Tobramycin

Valproic Acid Vancomycin

Thyroid function
Anti-TG

cobas e 601 assay menu Tumor markers


AFP CA 125 II CA 15-3 CA 19-9 CA 72-4 CEA CYFRA 21-1 free PSA NSE total PSA

Infectious diseases
Anti-HAV total Anti-HAV IgM Anti-HBc Anti-HBc IgM Anti-HBe Anti-HBs Anti-HCV HBeAg HBsAg HBsAg confirmatory HBsAg quantification CMV lgG

Anti-TPO Anti-TSHR Calcitonin1


FT3 FT4 T3 T4 T-Uptake Tg Tg hs1 TSH

Cardiac Fertility / hormones


ACTH C peptide Cortisol DHEA-S Estradiol FSH hCG+ hCG STAT Insulin LH Progesterone Prolactin SHBG Testosterone CK-MB (mass) CK-MB (mass) STAT Digoxin Digitoxin Myoglobin Myoglobin STAT NT-proBNP NT-proBNP STAT Troponin I Troponin I STAT Troponin T Troponin T STAT Troponin T hs Troponin T hs STAT

CMV lgM CMV IgG Avidity 1 HSV-11 HSV-2 1 HIV Antigen HIV Antigen confirmatory HIV combi HIV combi PT1 Rubella IgG Rubella IgM Toxo IgG Toxo IgM

Maternal care
free b hCG PAPP-A PlGF sFLT-1

Anemia
Ferritin Folate RBC Folate Vitamin B12

Bone markers
-CrossLaps Vitamin D3 (25-OH) Intact PTH N-MID Osteocalcin P1NP PTH STAT

Rheumatoid Arthritis
Anti-CCP

Critical care
IL6 BRAHMS PCT S100

Others
IgE

Assays currently under development 2 Partner Channel Last Update 03/2010


1