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IntroductiontoBiomedicalInformatics Introduction to Biomedical Informatics

Topic:OverviewofBMI

FundedbyNIHGrantXYZ Funded by NIH Grant XYZ

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Outline
Introductiontotheclass Motivatingexample:healthrecords Origins of BMI OriginsofBMI RelationshipofBMItootherdisciplines Dataacquisition,storage,anduse Electronic Medical Records ElectronicMedicalRecords Conclusionsanddiscussion Recommendedreading
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Whytakethisclass Why take this class


ThisclasswillNOT
t h teachyoutobeaprogrammer t b teachyoutofixbrokencomputers tellyouabouteveryimportantbiomedicalcomputingsystemor application

ThisclassWILL
introduceyoutoconceptsunderlyingbiomedicalinformatics enco rage o to read additional related material encourageyoutoreadadditionalrelatedmaterial helpyouconnectbroadconceptsinbiomedicalinformaticstoyour currentandfuturework

The practice of medicine is inexplicably entwined with the Thepracticeofmedicineisinexplicablyentwinedwiththe managementofinformation(Shortliffe&Cimino,3rd ed.)

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Motivatingexample:healthrecords Motivating example: health records


Modernpaperbasedrecordsgrewoutofthe conceptof labnotebooks for physicians concept of lab notebooksforphysicians Whataresomecurrentchallenges?

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Whatareallthethingsthatgointoamedical record?

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Whatareallofthewaysinwhichthemedical recordisused?

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Challengestoimplementingelectronicmedical records: d
Impossibletofullyautomaterecordkeepingprocesses Limitedstandardsforclinicalterminology,billinganddiagnostic codes,andinteroperabilityamongsystems(bothwithinonemedical centerandbeyondtomany) t db dt ) Dataprivacy,confidentiality,andsecurity(importantlythreedifferent butrelatedissues)

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Someterms Some terms


medicalcomputerscience informationscience i f ti i informationtheory biomedicalcomputingorbiocomputation medicalinformatics bioinformatics biomedicalinformatics biomedical informatics

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HistoryofBiomedicalInformatics
1890:Hollerithusedpunchcarddata p processingintheUScensus; ledto g ; epidemiologicalsurveillanceviapunch cards Late1950s:Startedtoseeapplicationsof digitalcomputersinmedicinein engineeringpublications g gp 1960s:ComputerScienceasadiscipline formed;mainframesthenorm formed; mainframes the norm 1970sand1980s:emergenceofthe personalcomputer(PC)ormicrocomputer personal computer (PC) or microcomputer

dannyman: punchcard loom (likely 19th ctry)

Marcin Wichary:1960s IBM punch card

jovike: 1978 IBM System/370 Model 145

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ThetermInformatics The term Informatics


1968:A.I.Mikhailov,alongwithotherscoinedtheterm InformatikaduringthedevelopmentofthefieldofInformation Informatika during the development of the field of Information ScienceinRussia 1976:NauchnyeKummunikatsiiInformatikaInformatics:the sc e f c d sc p e a s ud es e s uc u e a d ge e a scientificdisciplinethatstudiesthestructureandgeneral propertiesofscientificinformationandthelawsofallprocesses ofscientificcommunication. Late1960s:UniversitydepartmentsinFrance,Holland,and y p , , Belgiumestablishedwiththetitleinformatiquemedicale 1974:MedicalInformaticsbecamethetermofartatKings CollegeHospitalinLondon informfromdinformatique, g p q , aticsfromdautomatique.

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FormalDefinitionsandStandardsBodies
1985:AmericanStandardsforTestingMaterials(ASTM, developsvoluntarystandards)establishedSubcommitteeon MedicalInformatics 1986: AAMC defined medical informatics formally as a 1986:AAMC definedmedicalinformaticsformallyas a developingbodyofknowledgeandsetoftechniquesconcerning theorganizationandmanagementofinformationinsupportof medicalresearch,educationandpatientcare. medical research education and patient care Forthepurposesofthiscourse,Biomedicalinformaticsisa scientificfieldthatdealswithbiomedicalinformation,data, andknowledge theirstorage,retrievalandoptimalusefor problemsolvinganddecisionmaking.

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BiomedicalInformaticsApplicationDomains BiomedicalInformaticshasmajorapplication domains(subdisciplines)including: domains (sub disciplines) including:


Bioinformatics directedatthelevelofmolecularand cellularprocesses Clinical Informatics (a k a healthcare informatics) ClinicalInformatics (a.k.a.healthcareinformatics) directedatthelevelofindividuals(includesmedical informatics,nursinginformatics,dental,etc.) PublicHealthinformatics directedatpopulationsand p p society SocialInformatics socialimpactsofinformation technologyinhealthcarefield. I Imaginginformatics di t d t th l l f ti i i f ti directedattheleveloftissuesand d organs,e.g.,pathologyinformatics,radiologyinformatics

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HowdoyouthinkBiomedicalInformaticsrelatesto otherdisciplines? h di i li ?

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Outline
Introductiontotheclass Motivatingexample:healthrecords Origins of BMI OriginsofBMI RelationshipofBMItootherdisciplines Dataacquisition,storage,anduse El t i M di l R ElectronicMedicalRecords d Conclusionsanddiscussion Recommendedreading
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Medicalpracticeisallaboutgathering,reviewingandinterpretingdata
D t Dataarecentraltoallmedicalcare t l t ll di l Dataarecentraltotheprocessofdecisionmaking

Whataremedicaldata?

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Anindividualmedicaldatapoint(datum)isasingle observationaboutapatient b i b i
Thepatientinquestion Theparameterbeingobserved Thevalueoftheparameterinquestion Thetimeoftheobservation h i f h b i

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Medicaldataareuncertain.

Absenceofstandardmedicalvocabulariesbasedon cleardefinitionsmakesallmedicalobservationsfuzzy. Commonfindingsmaymaskrareones. Symptomsanddiagnosescancooccurevenwhennot related.

Contexthelpsremedythisissuetoadegree.

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Returntoour example:the medicalrecord

Legaldocument

woodenmask:ancestryrecordsfromlate1800s benben:modernclinic recordsstorage

Growingtendencytostructuredata Oftenreviewedintensely

mandiberg:medicalrecordunderreview

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Who(What)collectsmedicaldata? Who (What) collects medical data?


Physicians Nurses Radiologists Laboratory Officestaffsadmissionpersonnel Technologicaldevices

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PotentialUsesforMedicalInformation Potential Uses for Medical Information


HistoricalRecord Communication DiagnosisandMonitoring LegalRecords Legal Records Clinicaland/orEpidemiologicalResearch Perhapscustomtreatments/personalizedmedicine

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ProsandConsofPaperRecords p
+ Flexibility + Relative robustness Relativerobustness + Accessibility(paperis everywhere) + Familiarity
Logisticalissues - Unabletosharewithmultiple users - Theincompleteofthe records - Legibility - Disorganizationofthepaper records Redundancyandinefficiency InfluenceonClinicalResearch Accessibility(oncetherecordis Accessibility (once the record is entered,itshardtoaccessby paperalone) Illegibilityofproviderhandwriting Illegibility of provider handwriting

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GoalsofComputerizedRecords
Facilitatepatientcarebyservingasorganized externalmemoryforpractitioners Enhancecommunicationsbetweenprovidersand specialists Ensurecontinuityofcareduringinpatientstaysand acrossoutpatientvisits L l d fi Legalandfinancialpurposes i l Researchsupport

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ProsandConsofElectronicRecords
+ Accessibility remotelyand simultaneously + Legibility + Automaticdecisionmaking askingformissing information,alerts, reminders + Enhancedscope(haveall inpatientandoutpatient dataandtestresults availableevenifapatientis ) outsidelocalarea)
Initialinvestment Continuingcosts(training, maintenanceofconfidentiality, etc.) Subtlefailures(e.g.,transcription errorsofhandwrittennotesby dataentryperson) Catastrophicfailures Dataglutdifficulties(physicians oftenuseagreatdealofdataof lowdecisionvaluetomake smalldecisions.Captureis difficultandexpensive.)

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FactorsInfluencingBenefitsofEHR/EMRUse Factors Influencing Benefits of EHR/EMR Use


Comprehensivenessofinformation D ti Durationofuseandretentionofdata f d t ti fd t Degree of structure of data Degreeofstructureofdata Ubiquityofaccess q y

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AutomatedDataCapture Automated Data Capture


Recordingdatainthemomentcantakeapersonoutofthat g p moment(e.g.,notesinclass,recordsduringpatientvisit) Comprehensivecaptureofalldataisimpractical need priorities i iti Relyingonselfreportalonecanleadtomissinginformation Insufficient detail (tests were normal) avoided when test Insufficientdetail( testswerenormal )avoidedwhentest resultsautomaticallygatheredfromoriginalsource Chancetotrackdataprovenanceindetail
Formoreonthisissuefromacomputersciencestandpoint(ratherthanBMI),seeTruong,K.N.andHayes,G.R.Ubiquitous ComputingforCaptureandAccess,FoundationsandTrendsinHumanComputerInteraction:(2):2,95171.2009.

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Butwhendatacannotbegathered automatically ll
Emphasisonpersonnelinvestmentneeded Avoidanceoffreetextsinceinterpretationbyinput personnelintroduceserrors personnel introduces errors Carefulcoding emphasisontraining g p g Workonareastoincreaseaccuracyofdatainput(e.g., structureddataentry,voicerecognition)

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Medicalcareisinformational
Physicianencountersareinformationrich Whataresomeexamplesfromyourexperiences?

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Wheredidtheideaofstoringall thesedatadigitallyoriginate? these data digitally originate?


Asinotherdomains,complexityandquantityof informationrequiresdigitaldatabasesolutions(toa i f i i di i l d b l i ( degree) 1950s:Splitbetweenclinicalandresearchinformation repositories

1960s:adventofcomputerbasedhospital informationsystems(HIS) information systems (HIS) 1969:LawrenceWeedintroducedproblem orientedmedicalrecord(POMR) oriented medical record (POMR)

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EMR
Thesourceorientedinformationofamedicalchart plusademandorientedfrontend.(Stead,1987) Lindberg id l i db idealEMRconcepts:
Carefulmeasurementsoverpatientsconditionsshouldbemade, recordedandmonitored; Lifelongrecordmustbecompleteandmachinereadable; Linkagesshouldbeincludedtosourcesofmedicalknowledge.

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FunctionalComponentsofEMR Functional Components of EMR


Integratedviewofpatientdata Clinicaldecisionsupport Clinicianorderentry Accesstoknowledgeresources Access to knowledge resources Integratedcommunicationandreportingsupport

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WhatisthedifferencebetweenanEMRandan EHR?

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WhatissocomplicatedaboutEHR? What is so complicated about EHR? Lotsoftypesofdatatostore

L Lotsofpeopletomakehappy f l k h

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WhatdoestheEMRinparticularhavetodo?

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DesirableFeatures
Modular OpenSource(meansdifferentthingstodifferentpeople); Patientcentric Usableinresearchcontext(iftheclinicalsettingusingthe EMRdoesresearch)

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Issues,Barriers,Bottlenecks Issues, Barriers, Bottlenecks


Privacy Interoperability Standards Usability Workflow

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Oneexample: One example:


DemofromQuestSystem

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TranslatingMedicalDataintoKnowledge Translating Medical Data into Knowledge


Data:single,uninterruptedobservationpoint(e.g., g , p p ( g, oneBPreading) Information:elementsofdataarrangedtoconvey meaning Knowledge:generalizedtruthsformedfrom analysisofinformation l i fi f ti
Discuss:Whatisthedifferencebetweenadatabaseanda Discuss: What is the difference between a database and a knowledgebase?Whydoesitmatter?

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Discussion
Whatdoyouthinkisthelongtermrelationshipbetweenhealth workersandcomputers? workers and computers? Forthepractitionersintheclass,howhavethingschangedforyouin yourprofessionovertheyears? Will li i i Willcliniciansbeviewedasoutmodediftheydonotturnto b i d t d d if th d tt t computationaltoolsforassistance?

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RecommendedReading Recommended Reading


HeathandLuff Documentsandprofessionalpractice:bad organisationalreasonsforgoodmedicalrecords organisational reasons for good medical records MarcBerg Themultiplebodiesofthemedicalrecord Altman Informaticsinthecareofpatients:Tennotablechallenges Institute of Medicine Crossing the Quality Chasm: A New Health Systems InstituteofMedicine CrossingtheQualityChasm:ANewHealthSystems forthe21st Century Collen1995 ahistoryofmedicalinformaticsintheUnitedStates Weed1969 MedicalRecords,MedicalEvaluation,andPatientCare:The ProblemOrientedRecordasaBasicTool. bl d d l Chapters1,2,and12inbluebook p , ,

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