Lown Forum
We can learn about high blood pressure and how it should be managed by dissecting an example of a typical encounter between a patient and a doctor.
2011
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At the urging of his wife, a middle-aged lawyer went to a primary care physician. You should have your own doctor and not treat yourself, she had regularly reminded him. Soon after arriving at the doctors oce, a medical technician checked his vital signs temperature (98.6 degrees), height (59), weight (168 pounds), and blood pressure (an elevated 163/89). The patient insisted, Please take that blood pressure again. I never had high blood pressure before. The second reading produced 158/90. Lets try again in the other arm. 162/88. Now I have a problem that I didnt think I had an hour ago, he thought to himself. The physician conrmed the readings after checking the pressure lying down and sitting up, after 20 seconds of hyperventilating, and then again after about 10 minutes of reviewing the relevant medical history. The history included 10 to 12 hour workdays; frequent travel; take-out lunches and several evening meals at restaurants per week; nancial strains with a mortgage and tuitions; little time for exercise; and a family history of hypertension. He had no history of smoking, chest pain, or shortness of breath. His physical exam and electrocardiogram were normal. The check-up was uneventful except for two issues: the weight and the blood pressure. How should the physician approach this patient? How should the patient approach these new developments in his health? In this circumstance, and in most cases, the
The Lown Foundation is grateful to the Max Kagan Family Foundation for their steadfast support of our work for more than a decade. Their contributions have enabled us to advance our patient-centered model of health care here in Brookline, across the country, and around the world.
INSIDE
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Presidents message Meet the Lown Center echo sta Should I switch blood thinning meds? Welcome Andi Brown High blood pressure (cont.)
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Patient prole: Letting go for your health Assessing the value of care among providers A chair as treatment
NewsBeat
Eating healthy
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PrESIDENTS MESSAGE
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I have atrial brillation and I take Coumadin (generic: warfarin), I saw a commercial for a new blood thinning drug called Pradaxa. Should I switch?
Most people with atrial brillation require blood thinning medication, which helps reduce the risk of stroke. Approved in the 1950s, warfarin has been the best option. However, in November 2010, a new blood thinning drug called Pradaxa (generic: dabigatran) was approved by the FDA to be sold in the United States. A tremendous amount of interest is being paid to this potential alternative to warfarin and its easy to see why. Patients are often frustrated with warfarin because it requires frequent blood tests, modication in diet and avoidance of leafy, green vegetables, and it can interact with other medications. Taking warfarin can be timeconsuming and interfere with ones lifestyle. On the other hand, Pradaxa sounds promising. Initial study results show that Pradaxa is not only as eective as warfarin, but it may be slightly safer. Also, Pradaxa doesnt appear to interfere with ones diet and it requires far fewer blood tests. Its the rst time in over 50 years that warfarin has a serious competitor.
falling (often the elderly). Now that Pradaxa is available, there will be many more patients who take it, and in a year or two well have a much better idea of how Pradaxa does in dierent types of patients. Pradaxa has some additional shortcomings when compared to warfarin. Pradaxa is short-acting, which means it must be taken twice a day (warfarin is taken only once a day). Also, the cost for Pradaxa is signicantly higher (approximately $200 a month) and it is not yet clear which insurers will pay for Pradaxa and how much they will cover. Conversely, new advances in home monitoring for those taking warfarin were recently approved and are covered by Medicare and some insurers. This can decrease the amount of blood testing at the doctors oce that is associated with warfarin.
Possible concerns
This is a brand new drug, and it is not clear which populations would benet most and who might be more at risk. Older patients are often not well represented in the testing trials, and questions remain unanswered around patients who are at a higher risk for bleeding and
disease - should become the standard of care for everyone. Our philosophy is to recommend alternatives to invasive, costly procedures unless absolutely necessary, and that makes us a bit of a maverick in the current health care climate. We believe were in the vanguard, and with the help of the philanthropic community, were able to promulgate our style of care. Outcomes research and a planned conference on overtreatment in health care are two current projects Andi is working on, and she has several more exciting new activities in the works. Andi looks forward to working with donors, long-time and new alike, to ensure the Lown Foundations continued vitality and leadership position in patient-focused heart health.
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PATIENT PrOFILE
Sister Margaret also credits the care she receives at the Lown Center to her success living with high blood pressure. Dr. Blatt and the Lown Center have made a big dierence in my life. The care Ive received and their attention to my health has made me much more aware.
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A chair as treatment
Bernard Lown, MD
It has been 60 years since the publication of The chair treatment of acute coronary thrombosis. I co-authored this oddly-titled article with my mentor, Dr. Samuel A. Levine. Few studies have made as large an impact on the treatment of heart attack victims. I recall this seemingly ancient experience because of the lessons it holds for present-day health care. The study involved getting patients into a chair. This may sound bizarre. What is so novel about sitting? However, when I arrived at the Peter Bent Brigham Hospital (now Brigham and Womens Hospital) in 1950, patients experiencing an acute heart attack had traditionally been kept at strict bed rest for four to six weeks. Sitting in a chair was forbidden. They were not allowed to turn from side to side without assistance. During the rst week, patients were fed by a nurse. For the constipated, which included nearly every patient, precariously balancing on a bedpan was agonizing as well as embarrassing. The mortality was awesome. More than one in three patients died. Not surprisingly, many died from blood clots migrating to their lungs. Psychological depression was the rule. Other complications included intractable chest pain, prostatitis, severe constipation, bedsores, frozen shoulders, bone thinning, and collapsed lungs. Medical insistence on rigorous bed rest was based on a sacrosanct therapeutic principle, the need to rest a diseased body part, be it a fractured limb or a tuberculosis-infected lung. Unlike a broken bone, which could be immobilized in a cast, or a lung lobe, which could be collapsed by inating a chest cavity with air, the heart could not be rested so readily. The only approximation to the principle of rest for the diseased heart was to diminish its workload. Thus, bed rest was equated with heart rest. The study involved getting patients into a comfortable chair for increasing durations on succeeding days. By the end of the rst week, they sat up for several hours twice daily. Initially the house sta was vehemently opposed and resisted getting patients out of bed. They even accused me of committing crimes not unlike those of the Nazi experimentations. However, they rapidly became enthusiastic adherents. Patients required fewer narcotics for chest pain and less sedation for anxiety, and they could do without sleeping medications entirely. Nurses commented that the patients demeanor changed from anxious and depressed to more upbeat. The outcome of the study was impressive. During an average of four weeks of hospitalization, only eight of the 81 patients died. This was less than a third of the prevailing mortality among those admitted with an acute heart attack and subjected to bed rest. Although the chair treatment was initially questioned and even derided by the medical profession, rigorous bed rest was soon universally abandoned. Within a few years the period of hospitalization was reduced by half, rehabilitation was hastened, and patients return to work accelerated. In reecting on this experience many years later, I am troubled by the ways in which doctors rationalized a treatment that not only had little or no value, but exacted a draconian punishment to boot. Why subject heart attack victims to rigid bed rest that could only increase their misery and that led to major complications in those who already had a life threatening condition? This was not just a small error; it was a colossal misjudgment, yet another of the numerous examples of medical tradition derailing healthy skepticism and impeding a commonsense approach. A major reason that the detrimental eects of prolonged bed rest were not discovered earlier had to do with the physicians lack of attentiveness to their patients and even a failure to appreciate that churning emotions derange the functioning of every organ in the body, be it heart or intestine. That one can die from an aching heart is widely acknowledged. Even in this age of magical technology and miraculous scientic discoveries, the medical profession is remiss when not being attentive to the heartache that each and every human being experiences.
A hero to many
John Bogle, founder and retired CEO of the Vanguard Group, recently published a collection of essays that reect on our current nancial system. The book, entitled Dont Count On It, devotes four chapters to his heroes and mentors. In one of these chapters he highlights Dr. Lown, whom Mr. Bogle describes as John Bogle The paradigm of the healing physicians, creative, innovative, and world renowned cardiologist. His care carried me through the crucial middle years of my 34-year struggle with heart disease. Mr. Bogle continues, By dint of his powerful character and brilliant mind, Dr. Lown has lengthened and enriched the lives of countless patients...I owe my life to him. Mr. Bogle ends the chapter, Speaking for the world, for his patients, and for myself, Bernard Lown made things better for us all.
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NewsBeat
Benn Grover, Editor of ProCor, participated in the United Health/National Heart, Lung and Blood Institutes Chronic Disease Centers of Excellence semi-annual steering committee meeting in Washington DC on October 7-8, 2010. Dr. Barbara Roberts, Director of the Womens Cardiac Center at the Miriam Hospital and LCrF Board Member, was interviewed by Providence Business News on November 29, 2010 where she discussed the importance of prevention in the ght against heart disease. On December 9, 2010 Dr. Tom Graboys gave a talk at Beth Israel Deaconess Medical Center as part of their quarterly conference series. During his talk he discussed his perspective on the current state of the doctor-patient relationship. At the request of Dr. Andrew Weil, Dr. Graboys contributed a chapter on cardiac arrhythmias to a recently published book titled, Integrative Cardiology. Dr. Weil is an American author and physician, best known for establishing and popularizing the eld of integrative medicine. The Lown Center physicians regularly give lectures to community groups and organizations on heart health topics such as nutrition, exercise, coping with stress, second opinions, and alternatives to surgery. Dr. Vikas Saini spoke at the Goddard House in Brookline on January 24, 2011 and at the Watertown Mall on February 4, 2011. Dr. Brian Bilchik was a guest speaker during the Brookline Adult & Community Education winter semester. He also addressed the Brookline rotary Club on February 10, 2011. In January, the Foundation welcomed graduate consultant, Mychal Voorhees. She is a graduate student in the Health Communication program at Emerson College. Since moving to Boston in August 2009, Mychal has served as a communications intern with the EPA and Health resources in Action. Before moving to Boston to pursue her graduate degree, Mychal worked in the press oce at The Carter Center, a non-prot organization founded by President Carter, in Atlanta. Mychal will research successful communication strategies and create an outreach and marketing campaign for ProCor that targets medical school students and professors in developing countries.
Educational opportunities
Interested in hosting a lecture on a heart health topic by one of our physicians at your worksite or community organization? Please contact Jessica Gottsegen at jgottsegen@partners.org or 617-7321318 (x3805).
CONTACT US
Lown Cardiovascular Research Foundation
21 Longwood Avenue Brookline, MA 02446 USA (617) 732-1318 info@lownfoundation.org www.lownfoundation.org www.lowncenter.org www.procor.org
Advisory Board
Martha Crowninshield Herbert Engelhardt Edward Finkelstein William E. Ford renee Gelman, MD Barbara Greenberg Milton Lown John r. Monsky Jerey I. Sussman David L. Weltman
PAID
THE PRINT HOUSE
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Eating healthy
Fred Mamuya, MD, PhD
miso soup usually contains about 2500 mg of sodium. request no MSG when ordering Asian fare. Avoid condiments such as mustard, pickles, olives, or feta cheese. Soy or teriyaki sauce-based items should also be avoided for the same reason.
Taking the time to enjoy a home-cooked meal at the end of the day has the additional benet of encouraging healthier eating patterns to our loved ones.
Since prepared meals save time, but come at an unhealthy price, what is one to do? We should start by trying to minimize ordering out or buying prepared meals as much as we can. Increasing our dietary potassium is helpful in lowering blood pressure, and a DASH diet which emphasizes fruits, vegetables, low-fat food, and non-fat dairy products is recommended by most health professional organizations. If you are unable to locate appropriate educational materials, ask your physician during your next visit. Carefully thought-out meals cooked during the weekend can be recycled throughout the week. Meals prepared in a slow cooker can be cooked during the day while everyone is at work or school, and enjoyed together as a family at the end of the day. Taking the time to enjoy a home-cooked meal at the end of the day has the additional benet of teaching and encouraging healthier eating patterns to our loved ones.