Group II Electives
SUB CODE SUBJECT NAME L T P C
BI450 Microarray – Technique and applications 3 0 0 3
BI452 Protein engineering 3 0 0 3
BI454 Bioconfinement of Genetically Modified Organisms 2 0 2 3
BI456 Bioprocess Principles 3 0 0 3
BI458 Biodiversity and Management for Biotechnology 3 0 0 3
Group IV Electives
SUB CODE SUBJECT NAME L T P C
BI460 Management for Information Technology 3 0 0 3
BI462 Nanobiotechnology 3 0 0 3
BI464 Biopython 3 0 0 3
BI466 Microbial genomics 3 0 0 3
BI468 Systems biology 3 0 0 3
Group V Electives
SUB CODE SUBJECT NAME L T P C
BI461 Simulation and Modelling 3 0 0 3
BI463 Microfluidics 3 0 0 3
BI465 Evolutionary Computing 3 0 0 3
BI467 Plant genomics 2 0 0 3
BI469 Natural Language Processing 3 0 0 3
SCHEME OF EXAMINATION
Course Duration In Internal External Total Passing Minimum
Hours Marks Marks External Aggregate
All Theory And 3 hrs. 30 70 100 35 50
Practical Courses
Project Work 100 100 200 50 100
Comprehension 50 50 100 25 50
Seminar 100 -- 100 -- --
I SEMESTER
LE101 ENGLISH L T P C
3 0 0 3
PURPOSE
To provide an adequate mastery of technical and communicative English Language training
primarily, reading and writing skills, secondarily listening and speaking skills.
INSTRUCTIONAL OBJECTIVES
To provide language training to the engineering students which will enable them to understand
and acquire knowledge in technical subjects.
UNIT I LISTENING 5
1. Listening Comprehension – Listening Practice – Hints on Listening –
Practice Questions
2. Note Taking – Note Taking Strategies
UNIT II SPEAKING 7
• Expressing Opinions (agreement / disagreement) – Offering Suggestions Technical
Definition - Defining – Describing Objects - Exercise
• Audio equipment : Types of Pronunciation – Word stress / social context, science and
technology context-sentence stress and intonation.
UNIT IV WRITING 12
• Grammar – Parts of Speech(advanced) – prefixes and suffixes – Preposition + relative –
Tense forms – Active and Passive voice – Abbreviations – punctuation - Exercise
• Technical Report Writing – Lab Report - Exercise
• Art of Writing – Written Language – Rules for effective writing – Technical Essay Writing -
Exercise
• Letter Writing – Formal Letters – Letter to a News paper – Letter Inviting Dignitaries –
Letter of Application – Placing an Order – Curriculum Vitae – Invitation – Exercise
• Note Making – Strategies – Organising Notes - Exercise
•
UNIT V FOCUS ON AND COMMUNICATION AND “COMPUNICATION” 9
a) Communication – Basic Concepts – Process – Kinds – Routes – Forms –
Factors – Barriers – Triangles – Communication (Communicate through
Computers – Power Point & Tele Conferencing).
b) Dialogue Writing – How to write a dialogue - Enact dialogues between two or
three people
c) Mini Project Report Writing – Mini Project may submitted during course work –
Example Topics like Internet – Role of Language – Communication – Technology
– English Literature etc.
INTERNAL ASSESSMENT 5
Assignment and Mini Project Report Writing – Mini Project may be submitted during course work.
Based on the test performance and project report of the students marks may be awarded.
TOTAL 45
TEXT BOOKS
• Abraham Benjamin Samuel “Practical Communication (Communicative English),
LSRW2000”, SRMEC - June 2002
REFERENCE BOOKS
• Herbert. A.J. The structures of Technical English Orient Longman 1995.
• Pickett and Laster, ‘echnical English, Writing, Reading and Speaking’, New York
Harper and Row Publications, 1997.
• Swan, Michael, ‘Basic English Usage’, Oxford University Press, 1984.
• Interactive course in phonetics and spoken English published by Acoustics
Engineers(ACEN) 2002.
• Warner, Tony, “Communication Skills for Information Systems”, Pitman Publishing,
London, 1996.
• Munter, Mary, “Business Communication Strategy and Skill”, Prentice Hall Inc., New
Jersey, 1987.
• Day Robert.A. 1983, “How to Write and Publish a Scientific Paper” Vikas Publishing
House Pvt Ltd, New Delhi,1979.
• Staff of the Department of Humanities and Social Sciences, Anna University, “English
for Engineers and Technologist Vol. – I”. Orient Longman, 1990.
MA111 MATHEMATICS – I L T P C
(Common for BT, BI & GN Branches) 3 1 0 4
UNIT I – MATRICES 9
*Review of determinants, its properties and applications.
Rank of a Matrix – Consistency and Inconsistency of a system of m linear equations in ‘n’
unknowns – Eigen values and Eigen vectors – Cayley-Hamilton theorem – Diagonalisation –
Orthogonal Reduction of Quadratic forms to Canonical forms.
UNIT II - TRIGONOMETRY 9
*Review of complex numbers – De Moivre’s theorem and its applications
Expansion of sin nθ, cos nθ in terms of sin θ and cos θ. Expansion of tan nθ in terms of tan θ.
n n
Expansions of sin θ and cos θ in terms of sines and cosines of multiples of θ. Hyperbolic
functions and inverse hyperbolic functions. Separation into real and imaginary parts of complex
functions.
REFERENCE BOOKS
th
• Kreyszig.E, Advanced Engineering Mathematics, 8 edition, John Wiley & Sons,
Singapore, 2001.
• Veerarajan T., Engineering Mathematics, Tata McGraw Hill Publishing Co., New Delhi,
2000.
th
• Kandasamy P etal. Engineering Mathematics, Vol. I (4 revised edition), S.Chand &
Co., New Delhi, 2000.
• Narayanan S., Manicavachagom Pillay T.K., Ramanaiah G., Advanced Mathematics for
nd
Engineering students, Volume I (2 edition), S.Viswanathan Printers and Publishers,
1992.
nd
• Venkataraman M.K., Engineering Mathematics – First Year (2 edition), National
Publishing Co., Chennai, 2000.
• Ramamurthy V. etal. Engineering Mathematics – Vol. I & II, Anuradha Publications.
PH101 PHYSICS L T P C
(Common for all Branches) 3 0 0 3
PURPOSE
The purpose of this course is to develop scientific temper and analytical capability in the
engineering graduates through learning of physical concepts and their applications in engineering
and technology. Comprehension of some basic physical concepts will enable graduates to
logically solve engineering problems they would come across in the fast developing new
technologies in their engineering career.
INSTRUCTIONAL OBJECTIVES
At the end of the course, student should be able to:
1. Understand scientific concepts
2. Logically explain the concepts
3. Apply the concepts in solving engineering problems
4. Explain scientifically the new developments in engineering and technology
5. Relate industrial developments to developments in the physical phenomena
UNIT I ACOUSTICS 9
Vibrating systems - longitudinal and transverse waves – expression for velocity in solids and
fluids - Ultrasonic - production – magnetostriction and piezo-electric methods – properties –
applications in industry and medicine – acoustics of buildings (elementary ideas)
TOTAL 45
TEXT BOOKS
• Arumugam .M., “Engineering Physics”, Anuradha publishers 1998.
• Gaur & Gupta, “Engineering Physics”, Dhanpatrai & sons, V edition 1986.
• John Thiruvadigal.D, Ponnusamy.S, Vasuhi.P.S and Kumar.C, " Physics for
Technologies", Vibrant Publications 2004.
REFERNCE BOOKS
• Jordan.C.and Balmain.K.G. “Electromagnetic Waves and Radiating System,” (2nd ed.).
• Prentice Hall of India 1994
• Feynman R.P, Leighton R.B, Sands.M, “The Feynman Lectures on Physics Vol,I, II, III”,
Narosa publishing House, New Delhi 1995
• Thyagarajan.K.and Ghatak A.K.”Laser Theory and Applications”, Mac Millan India Ltd.
New Delhi 1992
• C.K.Kao “Optical Fiber System Technology, Design and Applications,” McGraw Hill,
1982
CY101 CHEMISTRY L T P C
(Common for all branches) 3 0 0 3
PURPOSE
To develop analytical capability to characterize, transform and use materials in engineering and
to have in depth knowledge of chemistry of matter.
INSTRUCTIONAL OBJECTIVES
At the end of the course:
• Student should be able to understand and explain the concepts logically.
• Apply knowledge gained in solving related engineering problems.
• Understand the role of applied chemistry in the field of engineering.
Waste water Treatment: Importance of dissolved oxygen in water – Determination of COD, BOD.
Treatment of domestic waste water- primary, secondary, tertiary treatment.
REFERENCE BOOKS
• Uppal M.M, “A text books of Engineering Chemistry”, Khanna Publishers.1986.
th
• Dara S.S, Chand S. & Co., “A text books of Engineering Chemistry”, 10 revised Ed,
2003.
nd
• Glasstone .S & Lewis, “Elements of Physical Chemistry” MacMillan Education 2 Ed,
1987.
• Kuriacose J.C. and Rajaram J. “Chemistry in Engineering and Technology”, Volume II,
Tata McGraw Hill p.b. Co., 1988.
INSTRUCTIONAL OBJECTIVES
• To know about different materials and their properties.
• Engineering aspects related to buildings.
• To know about importance of Surveying.
• To know about the transportation systems.
• To get exposed to the rudiments of engineering related to Dams, Water Supply and
Sewage Disposal.
REFERENCE BOOKS
• Rangwala,S.C., Engineering Materials, Charotar Publishing House, Anand, 1980.
• National Building Code of India, Part V, Building Materials, 1983.
• Surendra Singh, Building Materials, Vikas Publishing Company, New Delhi, 1996.
INSTRUCTIONAL OBJECTIVES
To familiarize with
• The Source of Energy and Power Generation
• The various metal joining processes and metal working process
• The Basic theory of Lathe & Drilling Machines
Sheet Metal Work-Introduction, equipments, tools and accessories, Sheet Metal working process
– various types, applications, advantages / disadvantages.
Drilling machine- Introduction, types, and description, drilling tools. Tapping – tap tools.
TOTAL 30
TEXT BOOKS
• Venugopal.K., “Basic Mechanical Engineering”, Anuradha Publishers, 1997.
• Prabhu.T.J., Jai Ganesh.V., Jebaraj.S., “Basic Mechanical Engineering”, Scitech
Publications, 2000.
REFERENCE BOOKS
• Hajra Choudhary S.K. & Hajra Choudhary A.K., “Elements of Manufacturing
Technology” Vol. I & II”, Media Publishers, 1986.
• Palanichamy M.S., “Basic Civil & Mechanical Engineering”, TMH, 1991.
INSTRUCTIONAL OBJECTIVES
At the end of the course students will be able
• To understand the basic concepts of magnetic, AC & DC circuits.
• To explain the working principle, construction & applications of DC & AC machines.
• To gain knowledge about the fundamentals of electric components, devices, Transducers,
Measuring Instruments & integrated circuits.
PART A
UNIT I MAGNETIC CIRCUITS 8
Definition of mmf flux and reluctance analysis of composite magnetic circuits, leakage flux,
fringing, magnetic materials and B-H relationship.
Faradays laws, induced emf’s and inductances. Energy storage in magnetic systems, Hysteresis
and eddy currents.
REFERENCE BOOKS
• Kothari D P and Nagrath I J, "Basic Electrical Engineering", Tata McGraw Hill, 1991
• Mithal G K, Electronic Devices & Circuits, Khanna Publications, 1997
• Ben .G. Streetman, "Solid State Electronics Devices, Prentice Hall of India, 1999
INSTRUCTIONAL OBJECTIVES
At the end of the course, student should be able to:
• Understand scientific concepts
• Develop the skill in arranging and handling different measuring instruments
• Determine the errors in various measurements and planning / suggesting how these
contributions may be made of the same order so as to make the error in the final result small.
LIST OF EXPERIMENTS
1. To determine the frequency of AC, using vibrating rod/tuning fork method.
2. Determination of velocity of ultrasonic waves in liquids.
3. Particle size determination using laser
4. Calibration of voltmeter & ammeter
5. Determination of field intensity – Field along the axis of a circular coil
6. Determination of wave length-Diffraction grating.
7. Determination of dispersive power of a prism using spectrometer.
8. Determination of laser parameters - divergence and wave length for a given laser
source – Laser Grating
9. Study of attenuation and propagation characteristics of an optical fiber cable.
10. Determination of temperature co-efficient of resistance - Carey –Foster’s Bridge.
TOTAL 30
REFERENCE BOOKS
• Ouseph C.G., Practical Physics , S.Viswanathan Publishers, 1981
• Aroro C.L., Practical Physics, S. Chand & Co., 1989.
• John Thiruvadigal.D, Ponnusamy.S, Vasuhi.P.S and Kumar.C, "Hand Book of Practical
Physics", Vibrant Publications 2004.
PURPOSE
An integrated laboratory course consists of experiments from applied chemistry and is designed
to illustrate the underlying principles of measurement techniques, synthesis, dynamics and
chemical transformation.
INSTRUCTIONAL OBJECTIVES
Students should be able to understand the basic concept and its applications.
LIST OF EXPERIMENTS
1. Estimation of total hardness, permanent and temporary hardness by EDTA method.
2. Determination of Chloride content in water by Volhard’s method.
3. Determination of COD in waste water.
4. Conductometeric titration – determination of strength of an acid.
5. Estimation of iron by potentiometer – titration.
6. Determination of molecular weight of polymer by viscosity average – method.
7. Determination of dissolved oxygen in a water sample by Winkler’s method
8. Determination of corrosion rate.
9. Determination of pH / Acidity of water sample.
10. Estimation of Copper in ore.
11. Estimation of nickel in steel.
12. Determination of solubility product of sparingly soluble salts.
TOTAL 30
REFERENCE BOOKS
• Practical Chemistry – I, 2004 Edited by Dr. R. Jeyalakshmi.
• Practical Chemistry by Kamaraj & Arthanareeswari, Sudhandhira Publications, 2003.
PURPOSE
To familiarize the students with the fundamentals of operating systems, office package tools and
Programming basics
INSTRUCTIONAL OBJECTIVES
1. Introduction to DOS, UNIX, Windows
2. Word , Excel, Powerpoint , Access
3. C Programming Basics
LIST OF EXPERIMENTS
CYCLE - I
Fundamentals of Computers and Introduction to Operating Systems
Organization of Computers, Generation, Modern Computers , Applications
Operating Systems : DOS , UNIX , WINDOWS , Introduction to GUI.
CYCLE-II
Office Automation
Word Processing , DataBase Management , Spread sheet Package , Presentation tools.
CYCLE –III
C Programming Basics
1. Sum of Series , Sine, Cosine, Exponential
2. Counting number of words,vowels, lines in a text
3. Programs using Builtin math functions
4. Conversions : Hex to Decimal, Binary to Octal etc.
5. Matrix operations : Multiplication, Symmetric, Inverse
6. Student mark processing
PURPOSE
To provide the students with hands on experience on different trades of engineering like fitting,
carpentary, smithy, welding and sheet metal.
INSTRUCTIONAL OBJECTIVES
To familiarize with
• The basics of tools and equipments used in fitting, carpentary, sheet metal, welding and
smithy
• The production of simple models in the above trades
LIST OF EXPERIMENTS
EMPHASIS TO BE LAID ON REAL LIFE APPLICATIONS WHEN FRAMING THE EXERCISES.
1. FITTING
Tools & Equipments – Practice in chipping, filing & Drilling. Making Vee Joints, Square, dovetail
joints, Key making.
2. CARPENTARY
Tools & Equipments- Planing practice- Making Half Lap, dovetail, Mortise & Tenon joints, a mini
model of a single door window frame( Frame only)
3. SHEET METAL
Tools & equipments – Fabrication of a small cabinet, Rectangular Hopper, etc.,
4. WELDING
Tools & equipments – Arc welding of butt joint, Lap Joint, Tee Fillet. Demonstration of Gas
welding, TIG & MIG.
5. SMITHY
Tools & Equipments – Making simple parts like hexagonal headed bolt, chisel.
TOTAL 45
REFERENCE BOOKS
• Kannaiah.P. & Narayanan,K.C. “Manual on Workshop Practice”, Scitech Publications,
Chennai, 1999.
• Venkatachalapathy, V.S. “First year Engineering Workshop Practice”, Ramalinga
Publications, Madurai, 1999.
II SEMESTER
MA142 MATHEMATICS II L T P C
(Bio-Technology) 3 1 0 4
UNIT I - ALGEBRA 9
Binomial, exponential and logarithmic series (without proof) – problems on summation,
approximation and coefficients.
TEXT BOOKS
th
• Kandasamy P etal. Engineering Mathematics, Vol. I (4 revised edition), S.Chand &
Co., New Delhi, 2001 (Unit I – Chapter 2,3,4)
th
• Grewal B.S., Higher Engineering Mathematics, 36 edition, Khanna Publishers, 2001
(Unit II – Chapter 5 except Section 5.6, 5.10, Unit III – Chapter 13 except Section 13.8
(II), 13.10, Unit IV – Chapter 8 Section 8.4 – 8.6, 8.8-8.18, Unit V – Chapter 3 Section
3.13 – 3.17)
REFERENCE BOOKS
th
• Kreyszig.E, Advanced Engineering Mathematics, 8 edition, John Wiley & Sons,
Singapore, 2001.
th
• Kandasamy P etal. Engineering Mathematics, Vol. I & II (4 revised edition), S.Chand &
Co., New Delhi, 2000.
• Narayanan S., Manicavachagom Pillay T.K., Ramanaiah G., Advanced Mathematics for
nd
Engineering students, Volume I, & II (2 edition), S.Viswanathan Printers and
Publishers, 1992.
• Venkataraman M.K., Engineering Mathematics – Vol.III – A (13th edition), National
Publishing Co., Chennai, 1998.
• Ramamurthy V, etal Engineering Mathematics Vol. I and II, Anuradha Publications.
CY152 CHEMISTRY II L T P C
3 0 0 3
PURPOSE
The course provides advanced topics in chemistry required for bio-technology. It covers important
aspects of metal complexes, colloids, toxicology, dynamics of chemical process and solutions
INSTRUCTIONAL OBJECTIVE
At the end of the course:
• Student should be able to understand and explain the concepts logically.
• Apply knowledge gained in solving related engineering problems.
• Understand the role of applied chemistry in the field of engineering.
TOTAL 45
TEXT BOOKS
• Puri B.H.and Sharma L.R., “Principles of Physical Chemistry”, S.Nagin Chand and
Company, Delhi (1994).
• Kund and Jain, “Physical Chemistry”, S.Chand and Company, Delhi (1996)
• Kuriacose J.C., and Rajaram,J., “Chemistry in Engineering and Technology “, Volume 1
& 2, Tata McGraw Hill Publishing Co., Ltd, New Delhi, 1989.
• “Comprehensive Chemistry to Bio-Engineers”, Dr.R,Jeyalakshmi, Dr.P.Kamatchi,
P.Ramar, S.Kannan, Devi publications (in print).
REFERENCE BOOKS
• Gordon M. Barrow, “Physical Chemistry”, Sixth Edition, Tata McGraw Hill (1996).
• Dr.Dhiraj sud "Engineering Chemistry" Millennium Edition S.K. Kataria and Sons, 2000.
• Dara S.S., “A text books of Engineering Chemistry”, S.Chand and company Ltd., 2003
revised edition..
• Samuel Glasstone, “Physical Chemistry”, Macmillan II edition, 1969.
• Sharma B.K. “Industrial Chemistry”, V Edition, Geol publishing House, Meerut, U.P., V
edition (1997 – 1998).
INSTRUCTIONAL OBJECTIVES
Basics of C Language and its constructs
Programming in preliminary and advanced levels
Detailed understanding of OOPs and C++ language
Understanding and programming in inheritance, polymorphism
L: 45 P: 30
Total: 75
TEXT BOOKS
• Mullish Cooper, “The Sprit of C”, Jaico books 2002
• Stephen Prata, “C++ Primer Plus”, fourth edition, 2003
REFERENCE BOOKS
• E.Balagurusamy , “Programming in C” , Tata McGraw Hill
• Harvey Deital and Paul Deital , “ C++ How to Program”
rd
• S. B. Lippman & J. Lajoie, “C++ Primer”, 3 Edition, Addison Wesley, 2000.
BT102 BIOCHEMISTRY L T P C
3 0 0 3
PURPOSE
Deals with the study of structural and functional aspects of biomolecules.
INSTRUCTIONAL OBJECTIVES
• To study the structure and properties of carbohydrates.
• Discuss the structure, properties and reactions of proteins and amino acids
• Discuss the structure, properties of fats and lipids
• To study the composition, structure and functions of nucleic acids
• To discuss the functions, deficiency symptoms, properties and structural aspects of
vitamins.
UNIT I CARBOHYDRATES 9
Definition, classification, preparation, properties, reactions, functions and structure of mono and
disaccharides. Polysaccharides – structural aspects of starch. Metabolism of carbohydrates.
UNIT II PROTEINS 9
Amino acids – classification, properties and reactions. Proteins – composition, classification,
general properties, reactions and functions. General structure of proteins – primary, secondary,
tertiary and quaternary. Structural aspects of insulin. Metabolism of proteins
UNIT V VITAMINS 9
Definition, classification, general sources, functions, deficiency symptoms, properties and
structural aspects of vitamin A,D,E,K,C, Thiamine, riboflavin, niacin and biotin.
TOTAL 45
TEXT BOOKS
• Lehninger A.L., Nelson D.L., Cox .M.M, “Principles of Biochemistry”, CBS Publications,
1993.
• Stryer L. “Biochemistry”, Fourth Edition, W.H. Freeman & Company, New York, 1999.
REFERNECE BOOKS
• Voet D. Voet G, “Biochemistry”, Second Edition, John Wile and Sons, 1994.
• Zubay.G, “Biochemistry”, Second Edition, Maxwell Macmillan International Editors,
1987.
• Conn, E and P.K. Stump, “Outlines of Biochemistry”, Willey Eastern Ltd., New Delhi,
1984.
th
• Albert, L. Lehninger et al, “Biochemistry”, 5 edition, Worth Publishing, 2000.
BT104 MICROBIOLOGY L T P C
3 0 0 3
PURPOSE
Introducing the fundamentals of microbiology through the study of the characteristics of
microorganisms, multiplication, growth in different media, metabolic pathways, effects of microbe
and their control.
INSTUCTIONAL OBJECTIVES
1. To highlight the roles and characteristics of microorganisms
2. To impart knowledge on the basic concept of replication in microorganisms
3. To study in detail the growth of microorganisms and impact of environment on their
growth
4. To evaluate explicitly, the metabolic pathways, role of microbes in public health; insight
into the physical and chemical control of microorganisms.
TOTAL 45
TEXT BOOKS
• Pelczar M.J, “Microbiology”, Chan ECS and Krieg NR
• Prescott, Harley and Klen, “ Microbiology”, McGraw Hill publications Fifth edition 2003
UNIT – I 3
Value Education—Introduction – Definition of values – Why values? – Need for Inculcation
of values – Object of Value Education – Sources of Values – Types
Values:
• Personal values
• Social values
• Professional values
• Moral and spiritual values
• Behavioral (common) values
UNIT- II 3
Personal values – Definition of person – Self confidence – Self discipline – Self Assessment –
Self restraint – Self motivation – Determination – Ambition – Contentment – Humility and
Simplicity - Sympathy and Compassion – Gratitude -Forgiveness – Honesty – Courtesy.
UNIT – III 3
Social values – Definition of Society – Units of Society - Individual, family, different groups –
Community – Social consciousness – Equality and Brotherhood – Dialogue – Tolerance –
Sharing – Responsibility – Co-operation Freedom – Repentance and Magnanimity.
UNIT – IV 3
Professional values – Definition – Competence – Confidence – Devotion to duty –Efficiency –
Accountablility – Respect for learning /learned – Willingness to learn-Open and balanced mind –
Team spirit – Professional Ethic – Willingness for Discussion – Aims – Effort – Avoidance of
Procrastination and slothfulness –Alertness.
UNIT – V 3
Behavioral values – Individual values and group values – Good manners at home and outside –
Equality – Purity of thought, speech and action – Understanding the role of religion – Faith –
Understanding the commonness of religions – respect for other faiths – unity in diversity – Living
together – Tolerance – Non-violence – Truthfulness – Common aim – Unified effort towards
peace – Patriotism.
TOTAL 15
REFERENCE BOOKS
• Dr. S. Ignacimuthu S. J., Values for life, Better yourself Books, Bandra
• Mumbai-600 050 (1999).
• Values(Collection of Essays)., Published by : Sri Ramakrishna Math., Chennai—
4.,(1996)
• Prof. R.P.Dhokalia.,Eternal Human Values NCRT –Campus Sri Aurobindo Marg., New
Delhi - 110 011.
• Swami Vivekananda., Education., Sri Ramakrishna Math., Chennai-4(1957)
• Tirukural (English Translation by Dr.G.U.Pope).
• The Bible
• The Kuran
• The Bagavath Geetha
GE 108 BIOLOGY L T P C
(Common for all branches) 2 0 0 2
PURPOSE
It makes the students knowledgeable in basic cognitive aspects of the brain and relations with
modern machines
INSTRUCTIONAL OBJECTIVES
• To study human systems – nervous system, circulatory system
• To understand brain functions
• To understand the cognitive aspects of the brain
• To relate man machine interaction towards product development.
UNIT IV MEMORY 6
Memory stratification, Methods of processes used by the memory manager, Genetic structure
REFERENCE BOOKS
• Cognitive aspects of the Brain Relations with modern computers, Jose Molina 2003,
Molwick.
PURPOSE
To draw and interpret various projections of ID, 2D and 3D objects.
INSTRUCTIONAL OBJECTIVES
To familarise with
The construction of geometrical figures
The projection of 1D, 2D & 3D elements.
REFERENCE BOOKS
• Bhatt.N.D., “Elementary Engineering Drawing”, (First Angle Projection), Charotar
Publishing Co., Anand, 1999.
• Venugopal .K, “Engineering Drawing & Graphics”, New age international Pvt. Ltd.,
1999.
INSTRUCTIONAL OBJECTIVES
Students should be able to understand the basic concept and its applications.
LIST OF EXPERIMENTS
1. Determination of TOTAL alkanity and acidity of a water sample.
2. Phase rule – simple eutectic ( two component system )
3. Estimation of percentage of lime.
4. Determination of rate constant for hydrolysis of ester.
5. Preparation of colloids solution (sol) of starch and its purification.
6. Determination of partition coefficient of iodine in water and carbon tetra chloride.
7. Determination of melting point and molecular weight.
8. Estimation of barium by gravimetric method.
9. Estimation of percentage composition of Glycerol (Viscometer method)
10. Estimation of Cobalt by gravimetry.
TOTAL 45
REFERENCE BOOKS:
• Practical Chemistry – II, 2004 –edited by Dr. R. Jeyalakshmi.
• Analytical Methods in Chemistry by Kamaraj & Arthanareeswari, Sudhandhira
Publications, 2004.
III SEMESTER
INSTRUCTIONAL OBJECTIVES
To impart knowledge on
• Nucleic acids and their characteristics
• Transcription and translation
• Gene regulation and mutation
• Mendelian genetics
TUTORIAL15
TOTAL 60
TEXT BOOKS
• T.A.Brown, “Genetics- A molecular approach”, Chapman & Hall, Third edition, 1998 -
for UNIT I, II & III.
• Benjamin Lewin, “Gene VII”, Oxford University Press, 2000- for UNIT I, II & III.
• Gardener, Simmons and Snustad, “Principles of Genetics “, John wiley & sons, 1991.-
for UNIT IV and V.
REFERENCE BOOKS
• H.K.Jain, “Genetics – Principles, Concepts, and Implications”, Oxford, 1999.
• C.B Powar, “Genetics – VOL 1 & 2”, Himalaya Publishing House, 2003.
• John Ringo,”Fundamental Genetics”, Cambridge, 2004.
BI 203 BIOPHYSICS L T P C
3 0 0 3
PURPOSE
To introduce the theories and concepts of biophysics of biomolecules which are considered
important in biotechnology applications.
INSTRUCTIONAL OBJECTIVES
• Learn the structures of biological molecules
• To understand the concepts of structural analysis
• Lear the techniques for analysis and determination of structure of biomolecules.
UNIT I INTRODUCTION 6
Levels of structures in biological macromolecules – Basic strategies in biophysics conformational
analysis – forces that determine protein and nucleic acid structure – basic problems – polypeptide
chain geometrics – potential energy – calculations – observed values for rotation angles,
hydrogen bonding, hydrophobic interactions and water. Structures – ionic interactions –
disulphide bonds.
BI205 BIOINFORMATICS L T P C
3 1 0 4
PURPOSE
Aims at providing an elementary knowledge of bioinformatics and Biological Information on the
web.
INSTRUCTIONAL OBJECTIVES
• Scope of bioinformatics
• Types of Databases and their use
• DNA structure and Analysis
• Pairwise and Sequence alignment
• Internet resources and Data mining.
UNIT–-I INTRODUCTION 9
Introduction - Definitions-Analytical approaches-Applications-Three Levels, Components and
Principles of Bioinformatics –Biological databases available in public domain-Inputs for
Emergence of Bioinformatics- Commercial uses of Bioinformatics-Role of Bio and Chemo
Informatics in drug design- Bioinformatics in Life sciences-Biological Information to knowledge-
Biocomputing -Developing Bioinformatics Computer Skills.
TEXT BOOKS
st
• T K Attwood, D J parry-Smith,”Introduction to Bioinformatics”,Pearson Education,1
th
Edition, 11 Reprint 2005.Chapters:
st
• C S V Murthy,”Bioinformatics”,Himalaya Publishing House,1 Edition 2003.Chapters:
REFERENCE BOOKS
• Stephen A.Krawetz,David D.Womble,”Introduction To Bioinformatics A Theoretical and
Practical Approach”,HumanA Press,2003
• Hooman H.Rashidi,Lukas K.Ruehler,”Bioinformatics Basics-Applications in Biological
Science and Medicine”,CRC press
• Jean-Michel Claverie,Cedric Notredame,”Bioinformatics-A Beginner’s Guide”,Wiley
• S.C.Rastogi & others, “ Bioinformatics- Concepts,Skills, and Applications”,CBS
Publishing,2003
• Michael R Barnes & Ian C Gray , “ Bioinformatics for Geneticists”,John Wiley,2003.
• Andreas D Baxevanis & B F Francis,” Bioinformatics- A practical guide to analysis of
genes & proteins”,John Wiley,2002
PURPOSE
The purpose of this subject is to study about the basic fundamentals of data structures and their
applications in ‘C’
OBJECTIVES
• Basic fundamentals and stack, queue Implementation
• Trees and their applications
• Various types of sortings
• Graphs and their applications
• Various search techniques
UNIT-III SORTINGS 9
Sorting- Exchange sorts-Selection and Tree sorting-Insertion Sort- Heap Sort- Merge Sort- Quick
Sort - Bucket Sort.
UNIT- V SEARCHING 9
Basic Search Techniques-Tree Searching-General Search Trees-Hashing
TUTORIAL 15
TOTAL 60
TEXT BOOKS
• Mark Allen Weiss,”Data Structures and Algorithm Analysis in C”,Addison Wesley
nd
Publications,2 Edition,1998.Chapters:2,3,4,5,6,7,9,10.
• Aaron M.Tanenbaum,Yedidyah Langsam,Moshe J.Augensten,”Data Structures Using
C”,PHI.Chapters:5,6,7.
REFERENCE BOOKS
• Jeffrev Esakov Tom Weiss,”Data Structures An Advanced Approach using C”,PHI.
• Alfred V.Aho,John E. Hopcroft,Jeffrey D.Ullman,”Data Structures and
th
• Algorithms”, 10 Reprint 2004, Pearaon Education.
• Jean-Paul Tremblay, Paul G.Sorenson”, An Introduction to Data Structures with
nd
Applications”,2 Edition,Tata Mcgraw-Hill Edition
OBJECTIVES
• Operators of Java and its applications
• Control statements of Java.
• Threading in Java.
• Event Handling and controls in Java
• Using Java in Bioinformatics.
UNIT- I INTRODUCTION 8
An Overview of Java: OOP, A Simple Program,Data Types,Variables, amd
Arrays,Operators:Arithmethic Operators, The Bitwise Operators, Relational Operators and Logical
Operators
UNIT- V APPLICATIONS 7
Application of Java in bioinformatics.
TUTORIAL 15
TOTAL 60
TEXT BOOKS
1. Herbert Schildt, “The Complete Reference JAVA 2 Fourth Edition”, Tata Mcgraw
Hill.Chapters:2,3,4,5,6,7,8,9,10,11,12
INTRUCTIONAL OBJECTIVES
To implement the following java Programming Techniques and to apply it in Bioinformatics.
LIST OF EXERCISES
INSTRUCTIONAL OBJECTIVES
The students should be able to develop their skills
Develop their skills in the preparation, identification and quantification of microorganisms
Isolation of plasmid DNA, genomic DNA and RNA
Electrophoresis
LIST OF EXPERIMENTS
1. Sterilization techniques
2. Media preparation
3. Microscopy and Micrometry
4. Isolation, enumeration and purification of microbes from a given sample
5. Staining Techniques (Simple, Gram staining, spore staining and Hanging drop technique)
6. Preparation of Agarose Gel
7. Isloation of Genomic DNA from blood
8. Isloation of RNA
9. Formaladyhyde gel elctrophoresis of RNA
10. UV mutation
IV SEMESTER
OBJECTIVES
• To provide basic knowledge about statistics
• To provide the calculation tools to various distribution methods.
• Testing techniques for samples.
• Analysis knowledge and correlation methods
TEXTBOOK
• Marcello Pagano and Kimberlee Gauvreau, “Principles of Biostatistics”, Thomson
nd
Learning, 2 Edition.
Unit I: 2.1,3.1-3.4
Unit II 6.1-6.3,7.1-7.4.
Unit III 9.1-9.4,10.4,12.1,15.1,11.1-11.2
Unit IV 12.1.1,12.1.2,12.2,14.6.
Unit V 17.1-17.3,18.1,18.2
REFERENCES:
• Wayne W. Daniel, “Bio statistics: A Foundation for Analysis in the Health sciences “ ,
th
John Wiley and Sons, 7 Edition
• Warren J. Ewens and Gregory R. Grant , “Statistical Methods in Bioinformatics an
introduction”, Springer International Edition
• N.Gurumani , “ An Introduction to BIOSTATISTICS”, MJP Publishers
rd
• Norman T.J. Bailey , “ Statistical Methods in Biology” , Cambridge, 3 Edition
INSTRUCTIONAL OBJECTIVES
This course emphasizes on the following:
• Importance of biological databases
• Different types of Biological databases
• DNA and genome sequencing methods
TUTORIAL 15
TOTAL 60
TEXT BOOKS
• T.K.Attwood, “Introduction to bioinformatics”, Prentice hall, I edition, 2001.
• P. K. Gupta, “Cell and Molecular Biology”, Rastogi publications, II edition, 2003.
REFERENCE BOOKS
• David W. Mount, “Bioinformatics: Sequence and Genome Analysis”, Cold spring harbor,
II edition, 2004.
• Arthur M.Lesk, “Introduction to bioinformatics”, Oxford university press, 2002.
BI204 GENOMICS L T P C
3 0 0 3
PURPOSE
The students will be aware of the structure and functions of the genomes together with the
computational approaches to analyze the genomes.
INSTRUCTIONAL OBJECTIVES
It gives emphasize on
• Structure, function and organization of genomes
• Computational approaches to analyze the genomes
• Microarray
• Functional and comparative genomics
TEXT BOOKS
• T.A.Brown, “Genome”, John Wiley & sons, II edition- for UNIT I & II.
• Bioinformatics: Sequence and Genome Analysis, David W. Mount, Cold Spring Harbor
Laboratory Press, I edition, 2001- for UNIT III & V.
• Stekel Dov, “Microarray bioinformatics”, Cambridge University Press, 2003- for UNIT IV.
REFERENCE BOOKS
• Issac S kohane, “Microarrays for an integrative genomics”, The MIT Press, 2002.
• Benjamin Lewin, “Gene VII”, Oxford University Press, 2000- for UNIT I, II & III.
INSTRUCTIONAL OBJECTIVES
• Notation and different types of Algorithms
• Mapping Algorithms and Greedy approaches.
• Dynamic programming for sequence alignment
• DNA analysis using graph Algorithms.
• Clustering and trees.
UNIT I INTRODUCTION
Algorithms and Complexity: Biological algorithms versus computer algorithms – The change
problem –Correct versus Incorrect Algorithms – Recursive Algorithms – Iterative versus
Recursive Algorithms – Big-O Notations – Algorithm Design Techniques.
TEXT BOOK
• Neil.C.Jones and Pavel.A.Pevzner, “An Introduction to Bioinformatics Algorithms”, MIT
Press, First Indian Reprint 2005.
REFERENCES
• Gusfields.G Algorithms on strings, trees and sequences: ComputerScience and
Computational Biology, Cambridge University Press 1997.
• Gary Benson Roderic page(Eds), “Algorithms in Bioinformatics”, Springer International
Edition, First Indian Reprint 2004.
UNIT I: INTRODUCTION
Overview of RDBMS, Advantages of RDBMS over DBMS, Normalization, Oracle data types.
Introduction to SQL, DDL, DML & TCL Commands. Data Definition Language, Data Manipulation
Language, Transaction Control & Data, Control Language Grant & Revoke Privilage Command.
REFERENCE BOOKS
• George Koch and Kevin Loney; ORACLE 8-The COMPLETE REFERENCE, Tata
MCGraw –Hill Edition, 1998.
• Michael Abbey and Michael J. Correy; ORACLE 8- ABEGINNERS GUIDE,1997
BI 210 PERL PROGRAMMING L T P C
3 0 0 3
TEXT BOOKS
• Harshawardhan P Bal,”Perl Programming for Bioinformatics”, Tata McGraw Hill,2003.
REFERENCE BOOKS
• D.Curtis Jamison, Perl Programming for Bioinformatics & Biologists, John Wiley &
Sons, INC., 2004
• Michael Moorhouse Paul Barry,” Bioinformatics Biocomputing and Perl”,Wiley
REFERENCE BOOKS
• Lab Manual
V SEMESTER
PURPOSE
This course helps the students to understand the proteomics and transcriptomics from the scratch
INSTRUCTIONAL OBJECTIVES
• Various Protein identification and Quantitation methods
• Protein chips
• Basics of Transcriptomics
UNIT I: INTRODUCTION 7
An Overview of Proteomics, Need, scope and challenges of proteomics, strategies for Protein
Separation: 2D gel electrophoresis- principle and applications, Liquid chromatography- principle
and applications, multidimensional liquid chromatography
UNIT V: TRANSCRIPTOMICS 10
Features of RNA secondary structure, Basics of RNA structure prediction, Limitations of
prediction, Development of RNA prediction methods, Methods –Self- complementary regions in
RNA, minimum free energy method, MFOLD, Sequence covariation method
TOTAL 45
TEXT BOOK
• R. M. Twyman, "Principles of Proteomics (Advanced Text Series)", Bios Scientific,
2004.
• David W Mount, "Bioinformatics- Sequence and genome analysis ", Cold Spring
Harbor Laboratory Press, second edition
REFERENCE BOOKS
• S. R. Pennington, M. J. Dunn, “Proteomics: From Protein Sequence to Function”,
Springer publications, first edition
PURPOSE
To learn the Internet Technologies
INSTRUCTIONAL OBJECTIVES
• To learn about Java, HTML, DHTML concepts
• To know about server side programming
• Knowledge of XML and its applications
TUTORIAL 15
TOTAL 60
TEXT BOOKS
• Deital and Deital, Goldberg, “Internet & World Wide Web, How To Program”, third
edition, Pearson Education, 2004
REFERENCE BOOKS
• Jame Jaworski, “Java unleased”, SAMS Techmedia Publications, 1999
• Naughton, Herbert Schildt, “Java2, Complete Reference”, 4th edition, TMH, 2000
• Deital & Deital, “Java How to program”, Prentice hall 2000
• Gary Cornell, Cay S.Horstmann, Core Java Vol.1 and Vol.2, Sun Microsystems
• T
ed coombs, Jason coombs, Brewer, “ Active X source book”, John Wiley
PURPOSE
This course enables to understand the concepts of Data Warehousing and Data Mining and its
applications in Bioinformatics
INSTRUCTIONAL OBJECTIVES
9. OLTP and Developing a Data Warehouse.
10. Data mining techniques and algorithms.
11. Data Mining environments and applications in Bioinformatics
TOTAL 45
TEXT BOOK
1. Berry and Linoff, “Mastering Data Mining: The Art and Science of Customer Relationship
Management”, John Wiley and Sons, 2001.
2. C.S.R. Prabhu, “Data Ware housing: Concepts, Techniques, Products
and Applications”, Prentice Hall of India, 2001.
3. L. De Raedt, A. Siebes, “Principles of Data Mining and Knowledge Discovery”, Springer
publications, 2001
REFERENCE BOOKS
• J.Han, M.Kamber, “Data Mining: Concepts and Techniques”, Academic Press, Morgan
Kanf man Publishers, 2001.
• Pieter Adrians, Dolf Zantinge, “Data Mining”, Addison Wesley, 2000.
rd
• W.H.Inmon, “ Building the DataWarehouse”, 3 Edition, Wiley Dreamtech 2002.
• Sam Anabory & Dennis Murray, “Data Warehousing in the real world”, Addisson
Wesley, 1997.
• Amitesh Sinha, “Data Ware Housing “, Thomson Asia, 2002.
PURPOSE
This course provides the basic concept of Phylogenetics and evolution at molecular level.
INSTRUCTIONAL OBJECTIVES
11. To understand the various methods of phylogenetic tree construction
12. Accuracies and statistical methods of optimization
13. Molecular evolution
UNIT II METHODS 9
Maximum parsimony methods: Strategies of searching for MP trees, consensus trees, branch
length estimation, weighted parsimony, MP methods for protein data, Maximum likelihood
methods
UNIT III STATISTICAL APPROACH 9
Optimization principle and topological errors, interior branch tests, bootstrap tests, Tests of
topological differences, advantages and disadvantages, molecular clocks and linearized trees
UNIT V: EVOLUTION 9
Molecular basis of evolution, synonymous and non- synonymous mutations, genetic
polymorphism and evolution, Population trees from genetic markers
TUTORIAL 15
TOTAL 60
TEXT BOOK
• Masatoshi Nei, “Molecular Evolution and Phylogenetics”, Oxford University Press, 2000.
REFERENCE BOOKS
• David W Mount, "Bioinformatics- Sequence and genome analysis ", Cold Spring
Harbor Laboratory Press, second edition
PURPOSE:
This subject gives the students an idea on the applications of information technology in medical
field.
INSTRUCTIONAL OBJECTIVES:
1. Hospital management and information system
2. Computer assisted instructions
3. Computer assisted surgical techniques
4. Telecommunications based systems
UNIT I: INTRODUCTION 9
Introduction, Hospital management and information system: functional area, pre-requisites,
integrated hospital information systems, health information system, and disaster management
plan
TOTAL 45
TEXT BOOKS
• Mohan Bansal, “Medical Informatics- a primer”, Tata McGraw-Hill, 2003.
REFERENCE BOOKS
Charles P. Friedman, Jeremy C. (EDT) Wyatt, “Evaluation Methods in Medical Informatics”,
Springer verlag, 1997
PURPOSE
This subject enables the students to learn about the protein and DNA structures, which are very
important in Bioinformatics
INSTRUCTIONAL OBJECTIVES
• Hierarchy of protein structure
• Super secondary structures of proteins
• Structure of DNA
UNIT I BASICS 9
Basics of protein structures, alpha helix, β sheets, loop regions, topological diagrams, and β
motifs: hairpin, Greek key, beta-alpha-beta, domains, and classes of proteins
REFERENCE BOOKS
• Voet D. Voet G, “Biochemistry”, Second Edition, John Wile and Sons, 1994
PURPOSE
To train the students to better in their overall competence
OBJECTIVES
The students will be able to improve the skills and learn new practices, emulate good manners
and get Good placement.
TOTAL 15
TEXT BOOK:
• S.P.Sharma “Personality Development”.
• Gearge Weinberg , “Practical Ways To A Powerful Personality”, 1999
• Dale Carnegie,”How To Win Friends And Influence People”, 2001
• Dale Carnegie, “Public Speaking”, 2000
REFERENCE BOOKS
• Sambrook et al “ Molecular Cloning” A Laboratory manual
PURPOSE
This laboratory course gives a complete understanding of the Internet programming concepts
using Java application, applets, HTML, XML and MS-FrontPage.
INSTRUCTIONAL OBJECTIVES
• Implementing HTML
• Practicing RMI, JDBC, JSP
• Animation concepts
LIST OF EXPERIMENTS
1. Exercises on creating HTML pages
2. Implementation of Package Bio-Data
3. Shapes Class Hierarchy
4. Animation using Java Applets
5. MS-FrontPage
6. Implementation of simple TCP/IP Client and server
7. Operations on Employee table using JDBC
8. Constructing a simple database using XML
9. An interactive Web application in JSP
10. Using cookies to track users in browsers from the web servers
11. Constructing a secured FTP client – server application
REFERENCE BOOKS
• Laboratory Manual
VI SEMESTER
PURPOSE
This course provides the fundamental knowledge on upcoming field of metabolomics and the
metabolic engineering in post genomics era.
INSTRUCTIONAL OBJECTIVES
• Metabolic engineering
• Comprehensive models cellular reactions
• Regulation of metabolic pathways
• Metabolic flux analysis and its applications
UNIT I: INTRODUCTION 9
Importance of metabolic engineering, Comprehensive models for cellular reactions, material
balances and data consistency
TOTAL 45
TEXT BOOK:
• Gregory N. Stephanopoulos, “Metabolic Engineering: Principles and Methodologies”,
Academic press, First Edition.
REFERENCE BOOKS:
• S. Cortassa, “An Introduction to Metabolic and Cellular Engineering”, World scientific
public company Ltd. 2002
BI302 CHEMOINFORMATICS L T P C
3 1 0 4
PURPOSE
This course provides knowledge on upcoming field of chemoinformatics.
INSTRUCTIONAL OBJECTIVES
• Molecular descriptors
• High throughput screening
• Virtual screening
• Combinatorial chemistry and library design
TUTORIAL 15
TOTAL 60
TEXT BOOK:
• Andrew R Leach, Valerie J Gillet, “An Introduction to Chemoinformatics”, Kluwer
academic publishers, 2003.
REFERENCE BOOKS:
• Johann Gasteiger, Thomas Engel, “ Chemoinformatics: A Textbook”, Wiley-VCH, 2003
PURPOSE
This course provides the fundamental knowledge of Molecular Modeling
INSTRUCTIONAL OBJECTIVES
• Basics in molecular mechanics
• Force fields
• Simulation methods
UNIT I INTRODUCTION 9
Useful concepts in Molecular Modeling- one electron and poly electron atoms and molecules-
molecular orbital calculations- Hartree-Fock equations
UNIT II ABINITIO METHODS 10
Approximate molecular orbital theories- semi-empirical methods- huckel theory- performance of
semi-empirical methods- Advanced ab initio methods, density functional theory and solid- state
quantum mechanics.
TUTORIAL 15
TOTAL 60
TEXT BOOK
• Andrew R. Leach, “ Molecular Modelling- Principles and applications”, Prentice hall, II
edition
PURPOSE
This course enables the students to understand the computational neuroscience from the basics.
INSTRUCTIONAL OBJECTIVES
• Neurons, Population dynamics
• Perceptions, models of neuroscience
• Supervised Learning and Rewards Systems
UNIT I: INTRODUCTION 9
Definition, Domains in Computational Neuroscience, Emergence and from exploration to a theory
of the brain, Modeling biological neurons, Basic synaptic mechanisms and the generation of
action potentials: Hodgkin-Huxley equations, dendritic trees, the propagation of action potentials,
and compartmental models, Hodgkin-Huxley neuron
TOTAL 45
TEXT BOOK
• Thomas Trappenberg, “Fundamentals of Computational Neuroscience”, oxford
University Press, June 2002.
REFERENCE BOOKS
• Lytton, William W, “From Computer to Brain - Foundations of Computational
Neuroscience, Springer publications, 2002.
PURPOSE:
This subject portraits the fundamentals and applications of computer aided drug designing
INSTRUCTIONAL OBJECTIVES:
• Fundamentals of Computer Aided Drug Designing (CADD)
• Drug development
• Methods and applications
TEXT BOOK
• Andrew R. Leach, “ Molecular Modelling- Principles and applications”, Prentice hall, II
edition (unit I)
• Rick Ng, “Drugs: From Discovery to Approval”, John Wiley & sons, 2004. (Units II, III).
• Paul S Charifson, “Practical Application of Computer-Aided Drug Design”,
OBJECTIVES
The students will be able to improve the skills and learn new practices, emulate good manners
and get good placement.
TEXT BOOK
• S.P.Sharma, “Personality Development”.
• George Weinberg , “Practical Ways To A Powerful Personality”, 1999
• Dale Carnegie,” How To Win Friends And Influence People”, 2001
• Dale Carnegie, “Public Speaking”, 2000
PURPOSE
Provides an opportunity to experimentally verify the theoretical concepts already studied. it also
helps in understanding the theoretical principles in a more explicit and concentrated manner
INSTRUCTIONAL OBJECTIVES
The students should be able to develop their skills
• Isolation of antibodies
• Purification of antibodies
• Immunoelectrophoresis
• Blood grouping
• Leucocyte count
• PBMC preparation and their enumeration
• Production of polyclonal antibodies – preparation of antigen – protocol for immunization
in rabbits
• methods of bleeding-purification of polyclonal antibodies
• Antigen-antibody reaction-Haemagglutination, precipitation-Widal and VDRL
• Immunodiffusion, Immunoelectrophoresis.
• Affinity chromatiography for antibody purification.
• ELISA-DOT and plate ELISA
• Western blotting
REFERENCE BOOKS
• A hand book of Practical and Clinical Immunology by Talwar GP and Gupta SK Vol.12
CBS Publication
INSTRUCTIONAL OBJECTIVES
• To identify the targets
• To find the possible drug targets
LIST OF EXERCISE
Homology modelling of proteins
Threading methods
Characterization of proteins
Analysis of 2D and 3D structures of proteins
Finding the active sites in a receptor
Docking methodologies
REFERENCE
• LAB MANUAL
VII SEMESTER
PURPOSE
This course gives a complete understanding of the concepts of Genetic algorithm.
INSTRUCTIONAL OBJECTIVES
Mathematical foundations for Genetic algorithm, operators
Applications of Genetic Algorithms.
Genetic based machine learning and its applications.
UNIT II GA OPERATORS 11
Data structures – Reproduction- Roulette-wheel Selection – Boltzman Selection – Tournament
Selection-Rank Selection – Steady –state selection –Crossover mutation – A time to reproduce,
a time to cross. – Get with the Main program. – How well does it work. – Mapping objective
functions to fitness forum. – Fitness scaling. Coding – A Multi parameter, Mapped, Fixed – point
coding – Discretization – constraints.
TEXT BOOK
• David E. Gold Berg, “Genetic Algorithms in Search, Optimization & Machine Learning”,
Pearson Education, 2001.
• S.Rajasekaran, G.A.Vijayalakshmi Pai, “Neural Networks, Fuzzy Logic and Genetic
Algorithms“, PHI, 2003 (Chapters 8 and 9).
REFERENCE BOOKS
• Kalyanmoy Deb, “Optimization for Engineering Design, algorithms and examples”, PHI
1995.
PURPOSE
This course provides the knowledge on advanced Molecular Modeling
INSTRUCTIONAL OBJECTIVES
Molecular dynamics simulation methods
Monte carlo simulation methods
Conformational analysis
Protein structure prediction methods
TUTORIAL 15
TOTAL 60
TEXT BOOK
• Andrew R. Leach, “ Molecular Modelling- Principles and applications”, Prentice hall, II
edition
INSTRUCTIONAL OBJECTIVES
Promise of personalized medicines
Pharmacogenetics
UNIT I: INTRODUCTION 8
Historical aspects of Pharmacogenetics, Pharmacogenomics, Biomarkers, and the promise of
personalized medicine
UNIV V: SAGE 7
Serial Analysis of Gene Expression (SAGE)- functional biology, mapping of disease loci
TOTAL 45
TEXT BOOK
• Werner Kalow, Rachel F Tyndale, Urs A Meyer, “Pharmacogenomics”, Marcel Dekker
Inc., 2001
REFERENCE BOOKS
• Adam Hedgecoe, “The Politics of Personalized Medicine: Pharmacogenetics in the
Clinic”, Cambridge University Press, first edition.
BI407 IMMUNOINFORMATICS L T P C
3 0 0 3
PURPOSE
This course gives the fundamental knowledge on Immunoinformatics
INSTRUCTIONAL OBJECTIVES
Methods Applied in Immunological Bioinformatics
Prediction methods
Application of microarray in Immunology
TOTAL 45
TEXT BOOKS
• Ole Lund, “Immunological Bioinformatics”, MIT press, September 2005
REFERENCE BOOKS
• Rammensee, “Immunoinformatics: Bioinformatics Strategies for Better Understanding
of Immune Function”, No. 254 [E-Book], Novartis Foundation
PURPOSE
This laboratory course gives a complete understanding of immuno informatics,
INSTRUCTIONAL OBJECTIVES
Immunoinformatics
LIST OF EXPERIMENTS
1. Immuno informatics
2. Epitope prediction
3. Conformational epitope prediction
4. Sequential epitope prediction
5. Promiscuous regions predictions
6. MHC-I binding sites predictions
7. MHC –II binding sites predictions
REFERENCE BOOKS
• Laboratory Manual
PURPOSE:
This is the first phase of the project work that is to be completed during the eighth semester. The
students are expected to form groups and finalize project title. Requirement specification and
design phases should be completed during the semester. The students are also expected to
show the profound percentage of their actual work. Internal Assessment will be based on the
reviews (minimum 2) conducted.
VIII SEMESTER
PURPOSE
Total Quality Technology includes a number of methodologies, tools and techniques used at
either or both strategic and operational levels
INSTRUCTIONAL OBJECTIVES
To deal with interface of total quality with wide spectrum of activities ranging from design,
purchasing, manufacturing, process control, technology, systems, maintenance, service and
customer satisfaction
.
UNIT I INTRODUCTION TO TOTAL QUALITY MANAGEMENT 6
Evolution to Total Quality Management – Classical approaches to TQM – Developed models of
TQM – Japanese versus American Approach towards TQM – Humanistic approaches of TQM –
contributors towards TQM –Authors: Edwards Deming, Joseph M.Juran, Philip B.Crosby, and
Genichi Taguchi
TOTAL 45
TEXT BOOK
• Sunil Sharma , “Total Quality Engineering Management”, –– Macmillan India
• Dr.D.D.Sharma – Sultan Chand, “Total Quality Management” –TQM – K.Sridhara Bhat
– Himalayan Pub.
• Dale H. Besterfield, “Total Quality Management” – Pearson Education, First edition.
REFERENCE BOOKS
• Sundarajan S.M., “Total Quality Management”, –, TAT Mc Graw Hill
• Bureau of IS, Guidelines for ISO 9000 implementation.
Group I Electives
PURPOSE
This course provides a fundamental knowledge of Digital Image Processing Techniques
INSTRUCTIONAL OBJECTIVES
Digital Image fundamentals, Image Transform
Image enhancement and restoration techniques
Image segmentation and Compression
TOTAL 45
TEXT BOOK
• Gonzalez, R.C and Woods, R.E, “Digital Image Processing “, Addition – Wesley, 2000.
• Anil.K.Jain “Fundamentals of digital image processing”, PHI, 1997.
REFERENCE BOOKS
• Umbaugh,S.E , “Computer vision and image processing”, Prentice Hall International,
Inc,1998
• William. K. Pratt, “Digital image processing”. Wiley Interscience, 2000.
BI352 GENETIC ENGINEERING L T P C
(same as BT303)
3 0 0 3
PURPOSE
Provides an opportunity to understand the theoretical concepts of genetic engineering principles
in a more explicit and concentrated manner.
INSTRUCTIONAL OBJECTIVE
• Learn the basic tools in recombinant technology
• Understand the various concepts of cloning vectors
• Learn the cloning strategies
• Acquire knowledge on the applications of genetic engineering
TOTAL 45
TEXT BOOK:
• T.A. Brown, “Gene Cloning and DNA Analysis: An Introduction”, Blackwell Science
(UK), 5th Edition, 2001
• Old R.W.Primrose SB, “Principles of Gene Manipulation, An Introduction to Genetic
Engineering”, Blackwell Scientific Publications
REFERENCES:
• Winnacker, “From Genes to Clones: Introduction to gene technology”, VCH publishers,
1987.
BI354 ARTIFICIAL INTELLIGENCE L T P C
(Same as IT459)
3 0 0 3
PURPOSE
The purpose of this course is to give students an in-depth understanding of Artificial Intelligence
methodologies, techniques, tools and results. Interactions between Artificial Intelligence and other
disciplines will be explored.
OBJECTIVES
To enable the student to understand
Various searching techniques used in problem solving, deal with ignorance and vagueness
Planning agents and the algorithm used.
UNIT I INTRODUCTION 6
What Is AI - The Foundations of Artificial Intelligence -The History of Artificial Intelligence,
Intelligent Agents-How Agents Should Act - Structure of Intelligent Agents -Environments
TOTAL 45
TEXT BOOK
• Stuart Russel and Peter Norvig, “Artificial Intelligence: A Modern Approach”, Prentice
Hall, 1995.
REFERENCE BOOKS
th
• George F Luger, “Artificial Intelligence”, Pearson Education, 4 Edition, 2001.
• Engene Charniak and Drew Mc Dermott, “Introduction to Artificial Intelligence”, Addison
Wesley, 2000.
• Nils J. Nilsson, “Principles of Artificial Intelligence”, Narosa Publishing House, 2000.
• Dan W. Patterson, “Introduction to Artificial Intelligence and Expert systems”, Prentice
Hall of India, 1992.
• Robert J Schalkoff, “Artificial Intelligence: An Engineering Approach”, McGraw Hill,
1990.
BI356 IMMUNOLOGY L T P C
(Same as BT207)
3 0 0 3
PURPOSE
Aimed at introducing the science of immunology and detail study various types of
immune systems their classification structure and mechanism of immune activation.
INSTRUCTIONAL OBJECTIVES
The immune system, their structure and classification, genetic control of antibody production
Cellular immunology
Mechanism of activation in hypersensitive immune reaction
UNIT V MOLECULARIMMUNOLOGY 7
Preparation of vaccines-application of DNA technologies catalytic antibodies-Immunotherapy with
genetically engineered antibodies-techniques-Immunodiffusion, RIA, ELISA western blot-Epitope
mapping
TOTAL 45
TEXT BOOK
• Janus Kuby “Immunology” W.H.Freeman&Co.
• Roitt, I.M., Brastoff.J., and Male D.K., “Immunology” Mosby Publication
PURPOSE
This course provides a way to study the Artificial Neural Networks and its applications.
INSTRUCTIONAL OBJECTIVES
To learn the basics of ANN in comparison with Human brain
To learn the various architectures of building an ANN and its applications
Advanced methods of representing information in ANN like self-organizing networks
and competitive learning
UNIT I INTRODUCTION 9
Artificial Neural Networks - Architectures, Definition and Fundamental Concepts - A Brief
Overview - Engineering Approaches to Neural Computing - The Mappings View point - The
Structure Viewpoint - Learning Approaches - Mathematical Foundations for ANN Study: Vector
and Matrix Fundamentals - Geometry for State - Space Visualization- Optimization.
UNIT II PERCEPTRONS 9
Elementary ANN Building Blocks: Biological Neural Units - Artificial Unit Structures - Unit Net
Activation to Output Characteristics - Artificial Unit Model Extensions - Single Unit Mappings and
Perceptron : Introduction - Linear Separability - Techniques to Directly Obtain Linear Unit
Parameters - Perceptrons and Adaline / Madaline Units and Networks - Multilayer Perceptrons -
Gradient Descent Training using Sigmoidal Activation Functions.
TOTAL 45
TEXT BOOK
Robert.J.Schalkoff, “Artificial Neural Networks”, McGraw Hill International Ed..1997.
REFERENCE BOOKS
James. A.Freeman and David. M.Skapura, “Neural Networks Algorithms, Applications and
programming Techniques”, Pearson Education, 2002.
Simon Haykin,"Neural Networks - A Comprehensive Foundation”, Pearson Education Asia. 2002.
B.Yegnanarayana,"Artificial Neural Networks", Prentice -Hal of India, 2001.
Group II Electives
INSTRUCTIONAL OBJECTIVES
Microarray designing
Image processing and normalization
Analysis of Microarray data
UNIT I: INTRODUCTION 9
Microarray- making and using microarrays, types of Microarray, sequence databases for
microarrays
TOTAL 45
TEXT BOOK
Dov Stekel,” Microarray Bioinformatics”, Cambridge University Press, 2003.
REFERENCE BOOKS
David W Mount, "Bioinformatics- Sequence and genome analysis ", Cold Spring Harbor
Laboratory Press, second edition
PURPOSE
The course imparts advanced knowledge on proteins through a detailed study of protein
Structure, its characteristics property and significance in biological systems
INSTRUCTIONAL OBJECTIVE
To focus and advanced knowledge on primary secondary structure of and their determined
Protein design principles and database analysis
UNIT I PRIMARY AND SECONDARY STRUCTURE 9
Primary structure and its determination secondary structure prediction and determination of super
secondary structures, proteins folding pathways.
UNIT II RECEPTORS 9
Membrane proteins and receptors, bacteriohodopsin, photosynthetic centres, epidermal growth
factor. Insulin and PDGF receptors and their interaction with effectors, protein phosphorylation,
immunoglobulins, Nucleotide and binding proteins, enzymes serine proteases, ribonuclease,
lysozyme
TOTAL 45
TEXT BOOK
• Moody PCE, and Wilkinson AJ – “ Protein Engineering ”, IRL press oxford 1990
• Branden C, Tooze R “Introduction of Protein structure”, Garland 1993.
REFERENCE BOOKS
• Creighton, TE, “ Proteins “, Freeman WH Second Ed 1993
BI454 BIOCONFINEMENT OF GENETICALLY MODIFIED L T P C
ORGANISMS
(same as GN451)
3 0 0 3
PURPOSE
This course deals with the importance of bioconfinement of genetically modified organisms.
INSTRUCTIONAL OBJECTIVES
• To make the students to understand the need of bioconfinement of genetically
engineered organisms
• To impart knowledge on methods of bioconfinement
TOTAL 45
TEXT BOOK
• Biological confinement of genetically engineered organisms by national research
council : National Academics press
PURPOSE
This subject puts emphasis on the basic engineering principles of bioprocess. It also highlights
the modern application of biotechnological process and the role of bio process engineer in
biotechnological industry
INSTRUCTIONAL OBJECTIVE
To study the historical development of bio process technology
To evaluate the kinetics and thermodynamics of enzymatic process
To teach the principle of sterilization design
To study the stoichiometry and energetics of cell growth and product formation
To evaluate the kinetics and mechanism of microbial growth
TOTAL 45
REFERENCE BOOKS
Bailey and Ollis, “Biochemical Engineering Fundamentals”, McGraw Hill (2nd Ed.). 1986.
Shule and Kargi, “Bioprocess Engineering”, Prentice Hall, 1992.
Alba S., Humphrey E and Milli N.R., “Bio Chemical Engineering”, Academic Press, 1973.
PURPOSE
This course creates awareness on the management, and diversification of bio-technological
processes
INSTRUCTIONAL OBJECTIVE
To introduce the characterizations and distributions of biodiversity
To familiarize the students, with the principles, monitoring, analysis of biodiversity and ecosystem
To emphasize on communication biotechnology
To highlight upon the economic values and human influences on biodiversity
To create awareness on measures for conservation of biodiversity
UNIT I INTRODUCTION 9
Introduction – characterization of biodiversity magnitude and distribution of biodiversity
Generation and maintenance and loss of biodiversity
TOTAL 45
TEXT BOOKS
Heywood V.H and Watscen R.T, “ Global Biodiversity Assessments ” Cambridge Univ Press 1995
PURPOSE
This course provides a way to learn the various pattern recognition techniques and their
applications.
INSTRUCTIONAL OBJECTIVES
Pattern features and Statistical techniques.
Cluster analysis and synthetic pattern recognition.
Feature extraction techniques and advances in the field.
UNIT I INTRODUCTION 7
Pattern and features – Training and learning in pattern recognition systems – Pattern recognition
approaches – Statistical pattern recognition – Syntactic pattern recognition – Neural pattern
recognition – Reasoning driven pattern recognition – Discriminant functions – Linear and Fisher’s
discriminant functions.
TEXT BOOK
Earl Gose, Richard Johnsonbaugh, Steve Jost, “Pattern Recognition and Image Analysis”,
Prentice Hall of India Private Ltd., New Delhi – 110 001, 1999.
Duda R.O. and Hart P.E., “Pattern Classification and Scene Analysis”, Wiley, New York, 1973.
REFERENCE BOOKS
Morton Nadler and Eric Smith P., “Pattern Recognition Engineering”, John Wiley and Sons, New
York, 1993.
Touand, Gonzalez R. “Patten Recognition Principles” Addison Wesley, 1974.
Robert J, Schalkoff, “Pattern Recognition: Statistical, Structural and Neural Approaches”, John
Wiley & Sons Inc., New York, 1992.
INSTRUCTIONAL OBJECTIVES
Fuzzy sets and representations.
Fuzzy relations and Logic.
Fuzzy systems and applications.
UNIT I INTRODUCTION 9
Crisp sets: an overview-Basic types of fuzzy sets - Basic Concepts of fuzzy sets-Characteristics
and Significance - Fuzzy sets Vs Crisp sets – Additional properties of Alpha Cuts –
Representation of Fuzzy sets – Extension principle for Fuzzy sets - Operations on Fuzzy Sets –
types of operations- Fuzzy compliments, Union, Intersection – Combination of Operations –
Aggregation Operations- Fuzzy Arithmetic – Fuzzy numbers – Linguistic variables – Arithmetic
Operation on Intervals And Fuzzy numbers – Lattice of Fuzzy numbers - Fuzzy Equation.
UNIT V APPLICATIONS 9
Engineering & Other applications – Introduction – Civil Engineering – Mechanical Engineering –
Industrial Engineering – Computer Science Engineering – Reliability Theory – Robotics –
Medicine – Economics – Decision Making-Fuzzy Systems & Genetic Algorithms – Fuzzy
Regression – Interpersonal Communication.
TOTAL 45
TEXT BOOK
George J. Klir & Bo Yuan, “Fuzzy Sets And Fuzzy Logic Theory And Applications
REFERENCE BOOKS
George J. Klir & Tina A. Folger,”Fuzzy Sets Uncertainty & Information”, PHI, 2001.
J.S.R.Jang, C.T.Sun, E.Mizutani, “ Neuro-Fuzzy and Soft Computing “, PHI, 2003
PURPOSE
This course on Computer Graphics will provide an in-depth knowledge of Graphics principles and
its applications.
INSTRUCTIONAL OBJECTIVES
Graphics Primitives and Hardware requirements.
2D and 3D representations and Algorithms.
User interfaces and Coloring and illumination techniques for surfaces.
UNIT IV 3D REPRESENTATION 9
Polygon Surfaces – Curved lines & Surfaces – Quadric Surfaces – Superquadrics – Spline –
Cubic Spline – Bezier Curves & Surfaces – B-Spline Curves & Surfaces – Beta Splines – Rational
Splines – Fractal Geometry Methods – Shape Grammar – Visualization of Data Set.
TOTAL 45
TEXT BOOK
Foley, Vandam , Feiner, Hughes , “ Computer Graphics: Principles & Practice”, Pearson
Education , 2000.
nd
Hearn.D , Baker.M.P , “Computer Graphics”, 2 edition PHI , 2001.
REFERENCE BOOKS
Harrington – “Computer Graphics”, McGraw Hill, 87.
nd
Newman W.M, Sproull R.F., “Principles of Interactive Computer Graphics” 2 edition, Tata
McGraw Hill, 1997.
BI457 ADVANCED JAVA PROGRAMMING L T P C
3 0 0 3
PURPOSE
This course provides an in-depth knowledge of Advanced Java language and programming.
INSTRUCTIONAL OBJECTIVES
Java Data structure.
Java Networking and Beans.
Java Data Base and Graphics.
TOTAL 45
TEXT BOOK
Jame Jaworski, “Java Unleashed”, SAMS Techmedia Publications, 1999.
REFERENCE BOOKS
Campione, Walrath and Huml, “The Java Tutorial”, Addison Wesley, 1999.
Duane A.Bailey, “Java Structures”, McGraw-Hill Publications, 1999.
Jeff Frentzen and Sobotka, ‘Java Script”, Tata McGraw-Hill, 1999.
PURPOSE
The 3D Modeling & Animation course is designed to teach the students the fundamentals of
producing professional quality animation products for a variety of multimedia environments.
INSTRUCTIONAL OBJECTIVES
To learn the Principles and techniques of computer generated modeling
To familiarize with the Principles and techniques of animation
To understand the Principles and techniques of 3D modeling and 3D animation.
UNIT IV 3D MODELING 9
Various Views – Primitive Placements – Modeling – Light rendered 3D Image.
UNIT V 3D ANIMATION 9
Lights – Camera – Object Animation – Object Metamorphosis – Hierarchical Motion Description –
Editing Motion Path – Rendering Animation – Exporting to other Environments.
TOTAL 45
TEXT BOOK
Michael O’Rourke, “Principles of 3D Computer Animation: Modeling, Rendering & Animation with
3D Computer Graphics”, Norton, 1998.
REFERNCE BOOKS
Brain A. Borsky, “Geometric Modelling Using Beta Splines”, Springer, 1989.
Hearn & Baker, “Computer Graphics”, Prentice Hall of India, 1996.
Group IV Electives
PURPOSE
Most professionals are deeply involved with information technology throughout their careers.
Many professionals elect to lead, or are asked to lead, an IT unit. This cross-disciplinary course
introduces students to the skills needed to manage modern IT organization.
OBJECTIVES
To understand dynamics of IT management, strategic planning and execution.
To know portfolio management and managing portfolio resources.
To learn to manage application development.
To understand and control information resources.
To understand and describe the role of various information specialists in the provision of systems
and services.
Learn to manage people.
To describe the global information environment and its impact on information systems and
services in organizations.
UNIT II IT TRENDS 9
Software and hardware trends-Advances in telecomm-Application portfolio resources:
Introduction-Application and data resource-process for portfolio management.
Managing application development: Traditional life cycle approach-Application project
management –Resource allocation and control-Alternatives to traditional development-Successful
end user computing.
TOTAL 45
TEXT BOOK
Carrol W.Frenzel, “Management of Information Technology”, Boyd and Frosee Publishing
Company, 1992
REFERENCE BOOKS
Dickson, Gary N, James Wetherbe, “Management Information System”, McGraw Hill, 1985.
BI462 NANOBIOTECHNOLOGY L T P C
PURPOSE
The subject focuses on the latest techniques and outcomes in Nanobiotechnology.
INSTRUCTIONAL OBJECTIVES
Bionanomachines
Biomolecular design
Structural and functional principles
Present and future of Nanobiotechnology
UNIT I: INTRODUCTION 8
Quest for Nanotechnology, from biotechnology to Bionanotechnology, unfamiliar world of
Bionanomachines, modern biomaterials, legacy of evolution
TEXT BOOK
David S. Goodsell, “Bionanotechnology: Lessons from Nature”, Wiley-Liss, 2004.
REFERENCE
Christof M. Niemeyer, “Nanobiotechnology: Concepts, Applications and Perspectives”, John
Wiley & Sons, 2004.
BI464 BIOPYTHON L T P C
PURPOSE
The subject focuses on the basic concepts and applications of Biopython.
INSTRUCTIONAL OBJECTIVES
Types and operators
Basic statements and functions
Modules and classes
Applications
UNIT II : FUNCTIONS 8
Functions basics, scope rules, argument passing, Odds and Ends, Function Gotchas
UNIT IV :TOOLS 10
Built-in Tools, Common Tasks in Python
UNIT V : APPLICATIONS 11
An Automated Complaint System, Interfacing with COM: Cheap Public Relations, A Tkinter-
Based GUI Editor for Managing Form Data, Design Considerations, And JPython: The Felicitous
Union of Python and Java
TOTAL 45
TEXT BOOK
Patrick O'Brien, “Beginning Python for Bioinformatics”, O'Reilly, 2002
REFERENCE
Cynthia Gibas, Per Jambeck, “Developing Bioinformatics Computer Skills”, O'Reilly, 2001
PURPOSE
It provides a comprehensive overview of Genomics study related to microbes.
INSTRUCTIONAL OBJECTIVES
Microbial Bioinformatics
Microbial metabolism
Genomics-Based Analysis of the Bacterial Cell Cycle
Plant pathogens
UNIT I: INRODUCTION 9
History, Bioinformatics and microbial pathogenesis, bacteriophage Bioinformatics
UNIT V: APPLICATION 9
Application of Genomics to Biocatalysis and Biodegradation, microbial proteomics
TOTAL 45
TEXT BOOK
Fraser, Claire M, Read, Timothy, Nelson, Karen E. “Microbial Genomes”, Humana Press 2004.
PURPOSE
It provides a comprehensive knowledge on the concepts and applications of systems biology.
INSTRUCTIONAL OBJECTIVES
Standard models and approaches in systems biology
Modeling of gene expression
Evolution and self organization
UNIT I: INTRODUCTION 8
Basic principles of systems biology, experimental techniques
UNIT V: APPLICATIONS 9
Systems biology in various fields, databases and tools, modeling tools
TOTAL 45
TEXT BOOK
Edda Klipp, Ralf Herwig, ”Systems Biology in Practice-Concepts, Implementation and
Application”, Wiley VCH, I Edition
Group V Electives
PURPOSE
It provides a comprehensive knowledge on simulation and modeling
INSTRUCTIONAL OBJECTIVES
Protein folding problem
Mathematical models
Computer simulation
TOTAL 45
TEXT BOOK
S. Sitharama Iyengar, “Computer modeling and simulations of complex biological systems”, CRC-
Press, second edition.
BI463 MICROFLUIDICS L T P C
PURPOSE
This subject facilitate the understanding of the latest concepts of Microfluidics
INSTRUCTIONAL OBJECTIVES
Micropumps and types
Design Rules for Micropumps
Modelling and Simulation
UNIT I: INTRODUCTION 9
Micropumps- mechanical micropumps, non- mechanical micropumps, Design Rules for
Micropumps, Preliminary Design, Compression Ratio, Criterion for Switching of Valve
TEXT BOOKS
Tay, Francis E.H., “Microfluidics and BioMEMS Applications”, Springer publications, 2002
PURPOSE
This subject provides the in-depth knowledge on evolutionary computing
INSTRUCTIONAL OBJECTIVES
Evolution strategies
Evolutionary programming
Memetic algorithms
UNIT I: EVOLUTIONARY ALGORITHM 8
Evolutionary algorithms, Components, Applications, evolutionary computing and global
optimization
TOTAL 45
TEXT BOOK
Eiben, A. E., Smith, J. E. “Introduction to Evolutionary Computing”, Springer publications, 2003.
REFERENCE
L. Kallel, B. Naudts, A. Rogers, “Theoretical aspects of evolutionary computing”, Springer
publications, 2001.
PURPOSE
This subject gives the overall idea on the basic concepts in plant genomics
INSTRUCTIONAL OBJECTIVES
Computational gene finding in plants
Computational modeling of gene structure in Arabidopsis thaliana
Directed plant transformation for the post-genomic era
UNIT I: INTRODUCTION 8
Comparative analysis of plant chromosomal DNA, Plant genome evolution: lessons from
comparative genomics at the DNA level
UNIT V: ADVANCES 10
Metabolomics - the link between genotypes and phenotypes, Gene replacement by homologous
recombination in plants, Recombinase-directed plant transformation for the post-genomic era
TOTAL 45
TEXTBOOKS
Chris Town, “Functional Genomics”, Springer; 1 edition
PURPOSE
To get people to understand as much as possible about important ideas in NLP and recent work
in NLP within one quarter.
INSTRUCTIONAL OBJECTIVES
This course is designed to introduce students to the fundamental concepts and ideas in natural
language processing (NLP), and to get them up to speed with current research in the area. It
develops an in-depth understanding of both the algorithms available for the processing of
linguistic information and the underlying computational properties of natural languages.
UNIT I INTRODUCTION 7
Introduction; Issues and Difficulties in NLP; Study of Language; Evaluating Language
Understanding System; Different Levels of Language; Representations; Organization of NLP
Systems; Linguistic Issues; Types of NLP Systems.
TOTAL 45
TEXT BOOK
James Allen, Benjamin & Cummings, “Natural Language Understanding”, Addison-Wesley Pub
Co, 2nd Edition 1995.
Ronald Hausser, Spring & Verleg, “Foundations of Computational Linguistics”, Springer Verlag,
1999.
REFERENCE BOOKS
Gerald Gazer and Chris Mellish, “Natural Language Processing for PROLOG Programmers”,
Prentice Hall of India, 1995.
Ashkar Bharathi & Vineet Chaitanya & Rajeev Sangal, “Natural Language Processing: A Paining
Perspective”, Prentice Hall of India, 1995.
Ralph Grishman, “Computational Linguistics: An Introduction”, Cambridge University Press, 1986.
Gross & Jones & Webber, “Readings in Natural Language Processing”, Morgan Konfmann
Publishers, 1986.
Werner, “Talking with Computers in Natural Language”, Springer Verlag, 1986.
“Building Natural Language Generation Systems”, Cambridge University Press, 2000.
BI402 PROJECT L T P C
0 0 16 8
BI404 COMPREHENSION L T P C
1 0 0 1