Mechanism of action
Indication
Contraindicati on
Adverse effect
Nursing alert
Omeprazole
Dosage
PO: 40 mg tab OD
Omeprazole is converted to active metabolites that irreversibly bind and inhibit H+-K+ATPase (an enzyme on the surface of gastric parietal cells). It inhibits transport of hydrogen ions into the gastric lumen. Omeprazole increases the gastric pH and reduces gastric acid formation
This medication was given to our patient Because his on NPO Diet which means the stomach of our patient continuously producing hydrochloric acid so to stop it the physician ordered omeprazole.
CNS: He a da c he , dizziness, asthenia, vertigo,insomnia, apathy,anxiety, paresthesias,drea m abnormalities Dermatologic: Rash,inflammation , urticaria, pruritus,alopecia, dry skin GI: Diarrhea, abdominal pain, nausea, vomiting, constipation, drymouth,
- Give before meals Rationale: to avoid stomach upset - Do not crush or chew tablets, swallow whole Rationale: chewed tablets and opened capsules decreased the effectiveness of drugs - Evaluate for therapeutic response like relief of Gastrointestinal symptoms Question if Gastrointestinal discomfort, nausea, and diarrhea occurs. Rationale: The patient is continually
28
evaluated for therapeutic response and the occurrence of drug side effects for evaluation of both the effectiveness and toxicity of the drug - when taking omeprazole be careful while driving or operating machinery because Dizziness may occur (avoid driving or performing hazardous tasks);headache (request medications); nausea,vomiting, diarrhea (maintain proper nutrition);symptoms of upper respiratory tract infection,cough (do not selfmedicate; consult with your health care provider if
29
uncomfortable). Rationale: Omeprazole generally does not cause any problems with your ability to drive a car or operate machinery. However, as with many other medicines, it could be dangerous if you were not fully alert
29
Name of drug
Mechanism of action
Indication
Contraindicatio n
Adverse effect
Nursing alert
Paracetamol
Dosage
Inhibits prostaglandi n synthesis in the CNS and blocks the pain impulse through a peripheral action. It acts on the hypothalamic heatregulating center, producing peripheral vasodilation. It results in antipyresis
This medication was given to our patient to Temporarily relieve pain and discomfort from fever, minor muscular aches, overexertion,
Early signs of toxicity: Anorex ia, nausea, diaphoresis (excessive sweating), generalized weakness within the first 12-24 hours.
- Assess patients pain or temperature before therapy and regularly thereafter Rationale: To indicate baseline data and monitor drugs effectiveness - Asses patients drug history and calculate total daily dosage accordingly Rationale: To prevent over dosage that could lead to toxicity and liver damage. - Be alert for signs of reactions and drug
28
Late signs of toxicity: Vomiti ng, right upper quadrant tenderness, elevated liver function tests within 48-72
interactions. Rationale: To establish proper preca utionary measures and management for possible adverse effects of drug. -Assess patients and familys knowledge of drug therapy.
Rationale: To determine the level of understanding of the patient and her family about the drug therapy
Name of drug
Mechanism of action
Indication
Contraindication
Adverse effect
Nursing alert
Ascorbic acid
GI: Nausea,
Classification: reactions, other metabolic Vitamin reactions. Vitamin C is involved in metabolism; carbohydrate utilization; Dosage synthesis of lipids, PO: 500 mg BID proteins, carnitine. It also preserves blood vessel integrity.
immune system.
alcohol, aspartame, saccharin, sugar, or tartrazine (FDC yellow dye #5) should be avoided in patients who have hypersensitivity or intolerance to these compounds.
vomiting, heartburn, diarrhea. Hematologic: Acute hemolytic anemia (patients with deficiency of G6PD); sickle cellcrisis. CNS: Headache (high doses). Urogenital: Arthritis, dysuria, crystalluria (high doses)
improvement (improved sense of well-being and sleep patterns). -Observe for reversal of deficiency symptoms (gingivitis, bleeding gums, poor wound healing, digestive difficulties, joint pain). Patient Teachings for Clients Taking Vitamin C -Abrupt vitamin C withdrawal may produce rebound deficiency. - Take large doses of vitamin C in divided amounts Rationale: the body uses only what is needed at a particular time and excretes the rest in urine
28
Name of drug
Mechanism of action
Indication
Contraindication
Adverse effect
Nursing alert
Tramadol
Tramadol binds to -opiate receptors and inhibits Classification: reuptake of norepinephrine Analgesic. and serotonin. It reduces intensity
should not be administered to patients who have previously demonstrated hypersensitivity to tramadol, any
agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting,
* For ambulatory patients: Be careful in rising and walking. Avoid driving and other potentially hazardous activities that require mental
28
of pain stimuli incoming from sensory nerve endings, altering pain perception and emotional response to pain. Dosage
severe pain.
diarrhea, loss of coordination, fainting; seizure (convulsions); a red, blistering, peeling skin rash; or shallow breathing, weak...
alertness until drugs CNS effects are known. * Avoid giving tramadol to patients with acute abdominal conditions Rationale: because it may mask evidence and disrupt assessment of the abdomen. * Monitor patient for drug dependence. Rationale: Drug can produce dependence similar to that of codeine or dextropropoxyphene and thus has potential for abuse.
Name of drug
Mechanism of action
Indication
Contraindicatio n
Adverse effect
Nursing alert
Ketorolac
Contraindicated with significant renal impairment, during labor and delivery , lactation, aspirin allergy, recent GI bleed or
- Patients who have asthma, aspirininduced allergy, and nasal polyps are at increased risk for developing hypersensitivity reactions. Assess for rhinitis, asthma, and
28
perforation
urticaria. - Ketorolac therapy should always be given initially by the IM or IV route. Oral therapy should be used only as a continuation of parenteral therapy. - Advise patient to consult if rash, itching, visual disturbances, tinnitus, weight gain, edema, black stools, persistent headche, or influenza-like syndromes (chills,fever,muscles aches, pain) occur. - Effectiveness of therapy can be demonstrated by decrease in severity of pain. Patients who do not respond to one NSAIDs may respond to another.
29
Name of drug
Mechanism of action
Indication
Contraindicatio n
Adverse effect
Nursing alert
Cefuroxime
Cefuroxime is used to our patient to prevent infection due to the Gunshot Wound.
*Contraindicated in patients hypersensitive to drug. * Use cautiously in patients hypersensitive to penicillin because of possibility of cross-sensitivity with other beta-
CV: phlebitis, thrombophlebitis GI: pseudomembran ous colitis, nausea, anorexia, vomiting, diarrhea Hematologic: transient
-Question for history of hypersensitivity to this drugs , particularly cephalosporins and penicillins. Rationale: to avoid allergy -Give without regards
28
lactam antibiotics.
Dosage
neutropenia, eosinophilia, hemolytic anemia, thrombocytopeni a Skin: maculopapular and erythematous rashes, urticaria, pain, induration, sterile abscesses, temperature elevation, tissue sloughing at intramuscular injection site Other: hypersensitivity reactions, serum sickness, anaphylaxis.
to meals. If GI upset occurs give with food or milk. -Avoid crushing tablets due to bitter taste. Rationale: chewed tablets decreased the effectiveness of drugs - Intramuscular injections must be administered deep IM rationale: to minimize discomfort. -Discomfort may occur with IM injection. -Doses should be evenly spaced. -Continue antibiotic therapy for full length of treatment.
29
29
Name of drug
Mechanism of action
Indication
Contraindica tion
Adverse effect
Nursing alert
Ciprofloxacin
Ciprofloxacin inhibits DNA enzyme in susceptible microorganisms . It interferes with bacterial DNA replication. Ciprofloxacin is also bactericidal.
Ciprofloxacin should be avoided by pregnant women as well as by lactating mothers since it could harm the baby. This drug is contraindicate d in patients who have shown hypersensitivit y to ciprofloxacin or to any other quinolones.
-severe dizziness, fainting, fast or pounding heartbeats -sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints; -diarrhea that is watery or bloody; -confusion, hallucinations, depression, unusual thoughts or behavior; -seizure (convulsions);
-Patients taking ciprofloxacin usually develop sensitivity of the skin to direct sunlight therefore these patients need to avoid direct exposure to the sun. -The medication should also be used with strict precautions in patients with history of seizures Rationale: it has been reported that this drug causes seizures.
Prescribed given:
30
Name of drug
Mechanism of action
Indication
Nursing alert
28
Methylcobal
Methycobal is a mecobalamin drug, a co-enzyme of Vitamin B that transpires in the blood and the cerebrospinal fluid. It is utilized by the nerve tissue more broadly than other homologues of vitamin B12.
Dosage
The drug is contraindicated to patients who has a known allergy to Mecobalamin. The drug is not recommended also with persons whoa re taking multiple medications. In such cases, it may be taken cautiously or unless if the drug is prescribed by your physician.
-Headache -Heat sensation -Feeling warm (general). -Pain around the intramuscular injection site -Pain at the intramuscular injection site -induration at the intramuscular injection site -A hardened mass forms within the muscle at the intramuscular injection site.
- While taking the drug Mecobalamin, it is not advised by the doctor to drink any alcoholic beverages because of the effects it produces on the drug. Patients with pernicious anemia may have to take the drug for the rest of his/her life to -Avoid irrevocable damage to the spinal cord. It is necessary to check your blood every three to six months to monitor progress.
29
29
Name of drug
Mechanism of action
Indication
Contraindicati on
Adverse effect
Nursing alert
Etoricoxib
The mechanism of action of this drug is a COX-2 selective Classification: inhibitor. This drug selectively inhibits Analgesic isoform 2 of cyclooxyginase enzymes /NSAID (COX-2). This reduces the generation of prostaglandins (PGs) from Dosage arachidonic acid. PO: 120 mg 1 Among the different cap OD for functions exerted by pain PGs, their role in the inflammation cascade should be highlighted. This drug non-steroidal anti-inflammatory drugs (NSAIDs). Prescribed COX is involved in given: producing prostaglandins, in August 23, response to certain 2011 diseases and injury.
-This medication is a nonsteroidal antiinflammator y drug (NSAID), prescribed for osteoarthriti s, rheumatoid arthritis and gouty arthritis. -relief of chronic musculoskel etal pain -relief of acute pain
Contraindicated in patients with peptic ulcer, severe heart disease, stroke, and hypersensitivity.
Central Nervous Systemnervousness, depression, drowsiness, insomnia, vertigo and ringing in the ear. Heart- Chest pain, high blood pressure and fluid retention. Metabolic- Taste disturbances, mouth ulcer, loss of appetite and weight loss. MiscellaneousKidney damage, fever, GI disorders, muscle pain and influenza-like syndrome.
-Administer with foods rationale: to prevent GI upset. -Use cautiously in patients with renal/liver dysfunction Rationale: to monitor for hepatic Failure and impair renal function -advice patient to avoid alcohol intake Rationale: GI upset or Gastric ulcer may result. -Instruct the patient to report occurrences of side effects. Rationale: To establish proper prec autionary measures
29
30