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Drug name

Indication and Dosage


Adverse effect GI: Nausea, vomiting, heartburn, diarrhea. Hematologic: Acute hemolytic anemia (patients with deficiency of G6PD); sickle cell crisis. CNS: Headache (high doses). Urogenital: Urethritis, dysuria, crystalluria (high doses). Other: Mild soreness at injection site; dizziness and temporary faintness with rapid IV administration.

Contraindication Use of sodium ascorbate in patients on sodium restriction; use of calcium ascorbate in patients receiving digitalis. Safety during pregnancy (category C) or lactation

Nursing Consideration Assessment & Drug Effects Lab tests: Periodic Hct & Hgb, serum electrolytes. Monitor for S&S of acute hemolytic anemia, sickle cell crisis. Patient & Family Education Take large doses of vitamin C in divided amounts because the body uses only what is needed at a particular time and excretes the rest in urine. Megadoses can interfere with absorption of vitamin B12. Note: Vitamin C increases the absorption of iron when taken at the same time as iron-rich foods

Ascorbic Acid

Prophylaxis and treatment of scurvy and as a dietary supplement. Increases protection mechanism of the immune system, thus supporting wound healing. Necessary for wound healing and resistance to infection.


Drug name Seroquel

Indication and Dosage indicated for the short-term treatment of acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.

Classification Anti-Psychotic

Adverse effect Side effects of Seroquel may include mood or behavior changes, constipation, drowsiness, headache, and trouble sleeping. Older adults with dementia may have a slightly increased risk of death when taking this medication.

Contraindication Seroquel contraindications include hypersensitivity to the medication or any of its ingredients. People with a history of seizures should consult their doctor before using Seroquel, as should patients with cardiovascular disease, cerebrovascular disease, dehydration, diabetes, hyperglycemia, pancreas problems, hypovolemia, Alzheimer's disease, hypothyroidism, pregnancy, and hepatic impairment.

Nursing Consideration

-Monitor patient for tardive dyskinesia. Condition may not appear until months or years after starting drug and may disappear spontaneously or persist for life, despite discontinuation of drug. -Monitor patient's vital signs carefully, especially during the 3- to 5day period of initial dose titration, when re-initiating treatment, or when increasing dosages. -Assess patient's risk for physical injury due to drug's CNS side effects. -Be alert for adverse reactions and drug interactions. -Evaluate patient's and family's knowledge of drug therapy.