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  • Gene Expression Altered in Postmortem Autism Brains

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    The Simons Foundation
    29 tayangan3 halaman
    Postmortem brain tissue from people with autism shows differences in expression of genes involved in a number of molecular pathways. Largest brain imaging study ever performed identifies candidate genes that influence brain size and general intelligence. Autism-associated variant in a gene that regulates the chemical messenger serotonin leads to autism-like behaviors in mice.

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    Newsletter 120424

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    Postmortem brain tissue from people with autism shows differences in expression of genes involved in a number of molecular pathways. Largest brain imaging study ever performed identifies candidate genes that influence brain size and general intelligence. Autism-associated variant in a gene that regulates the chemical messenger serotonin leads to autism-like behaviors in mice.

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    29 tayangan3 halaman

    Gene Expression Altered in Postmortem Autism Brains

    Diunggah oleh

    The Simons Foundation
    Postmortem brain tissue from people with autism shows differences in expression of genes involved in a number of molecular pathways. Largest brain imaging study ever performed identifies candidate genes that influence brain size and general intelligence. Autism-associated variant in a gene that regulates the chemical messenger serotonin leads to autism-like behaviors in mice.

    Hak Cipta:

    Attribution Non-Commercial (BY-NC)
    Unduh sebagai PDF, TXT atau baca online dari Scribd
    Tandai sebagai konten tidak pantas
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    SFARI NEWS

    le:///Volumes/Macintosh HD/Users/pkaplin/Desktop/120424/...

    24 April 2012

    A Newsletter from the Simons Foundation Autism Research Initiative

    NEWS Gene expression altered in postmortem autism brains Giant imaging study identifies genes that govern brain size IN BRIEF Genetics: Environment modulates autism symptoms in mice Cognition and behavior: Reward circuit abnormal in autism Molecular mechanisms: Serotonin regulation linked to autism TOOLBOX Chili pepper protein can alter behavior of mice BLOG Rate debate New diagnostic

    NEWS

    Gene expression altered in postmortem autism brains


    Postmortem brain tissue from people with autism shows differences in the expression of genes involved in a number of molecular pathways, including those that control cortical patterning, programmed cell death and differentiation, according to research published last month in PLoS Genetics.

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    Giant imaging study identifies genes that govern brain size


    The largest brain imaging study ever performed has identified candidate genes that influence brain size and general intelligence, according to research published 15 April in Nature Genetics.

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    SFARI NEWS

    le:///Volumes/Macintosh HD/Users/pkaplin/Desktop/120424/...

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    IN BRIEF

    Genetics: Environment modulates autism symptoms in mice


    Mutant mice with autism-like behaviors have fewer behavioral impairments when provided with toys, exercise wheels and contact with other mice, than do those that live in typical laboratory cages, according to a study published 5 April in Human Molecular Genetics.

    Read More >

    Cognition and behavior: Reward circuit abnormal in autism


    The reward center of the brain is less active in children with autism compared with controls in response both to praise and monetary rewards, according to a study published 11 April in Social Cognitive and Affective Neuroscience.

    Read More >

    Molecular mechanisms: Serotonin regulation linked to autism


    An autism-associated variant in a gene that regulates the chemical messenger serotonin leads to abnormal serotonin regulation and autism-like behaviors in mice. The results were published 3 April in the Proceedings of the National Academy of Sciences.

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    TOOLBOX

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    SFARI NEWS

    le:///Volumes/Macintosh HD/Users/pkaplin/Desktop/120424/...

    Chili pepper protein can alter behavior of mice


    By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.

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    BLOG

    Rate debate
    Do rising rates of autism point to a true increase in prevalence or simply reflect a growing awareness and thus diagnosis of the disorder?

    Read More >

    New diagnostic
    Parents searching for a genetic diagnosis for their child with autism now have a new option: a test that analyzes 62 different genes linked to syndromic autism, meaning cases of the disorder caused by mutation of a single gene.

    Read More >

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