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(DMB 21)

M.Sc. (Final) DEGREE EXAMINATION, JUNE 2010. Second Year Microbiology Paper V MEDICAL MICROBIOLOGY Time : Three hours Maximum : 100 marks PART A (5 8 = 40 marks) Answer any FIVE questions. 1. 2. 3. 4. 5. 6. 7. 8. Endotoxins. Inflammation. Drug resistance. Asperigillosis. Chicken pox. Hepatitis-B. A2T. Amphotericin-B. PART B (4 15 = 60 marks) Answer ALL questions. 9. (a) Describe the normal flora human body and their significance. Or Elaborate the role of biological barriers to infection.

(b)

10.

(a)

How Neisseria menegitis in transmitted and elaborate its pathogenesis? Or

(b)

What is subcutaneous mycoses and elaborate on sporotrichosis? Write an essay on poliomyolitis and its control. Or

11.

(a)

(b)

Outline the protozoan diseases taking the example of entamoeba histolytica. Explain the antibacterial drugs that act on protein synthesis of bacteria. Or

12.

(a)

(b)

Describe the biochemical tests used for diagnosis of bacterial pathogens.

(DMB 21)

(DMB 22)
M.Sc. (Final) DEGREE EXAMINATION, JUNE 2010. Second Year Microbiology Paper VI IMMUNOLOGY AND CELLULAR MICROBIOLOGY Time : Three hours Maximum : 100 marks

PART A (5 8 = 40 marks) Answer any FIVE questions. 1. 2. 3. 4. 5. 6. Humoral Immunity. Macrophages. IgG structures. Anaphylaxis. Phagocytosis. Zipper mechanism.

7. 8.

Quorum sensing. Apoptosis. PART B (4 15 = 60 marks) Answer ALL questions.

9.

(a)

Outline the structure lymphoid organs. Or

and

function

of

(b)

Elaborate on the nature, structure and function of MHC. Explain the principle and application of ELISA. Or

10.

(a)

(b)

Give an account of autoimmune diseases and their control. Describe the bacterial Toxins and their mode of actions. Or

11.

(a)

(b)

What are secretion systems and elaborate on T-complex transfer system of Agrobacterium? 2

(DMB 22)

12.

(a)

Write an essay on prokaryotic cell to cell signalling. Or

(b)

Focus extracelluar first messengers and intracellular second messengers.

(DMB 22)

(DMB 23)
M.Sc. (Final) DEGREE EXAMINATION, JUNE 2010. Second Year Microbiology Paper VII MICROBIAL GENETICS AND MOLECULAR BIOLOGY Time : Three hours Maximum : 100 marks

PART A (5 8 = 40 marks) Answer any FIVE of the following. All questions carry equal marks. 1. 2. 3. 4. 5. 6. 7. 8. Conjugational gene making in bacteria. Genetic recombination by transduction. Unidirectional replication of DNA. Denaturation and renaturation of DNA. Transcription and translation. nif gene regulation in Rhizobium. Composit transposons and Tn3 transposons. Conservative and replicative transposition.

PART B (4 15 = 60 marks) Answer any FOUR questions. All questions carry equal marks. 9. (a) Explain the genetic recombination bacteria by transformation. Or (b) What are plasmids? Write an different plasmids and their application. What is mutation? Explain different types of mutations. Or (b) Write an the genetic code and its significance in biology. Explain the concept of operon. Write an repressible and attenuation regulation of gene expression. Or (b) Write a comparative explanation for protein synthesis in bacteria and yeasts. 2 in

10.

(a)

11.

(a)

(DMB 23)

12.

(a)

Explain different tools used in r-DNA technology. Or

(b)

Write an various applications of plans and animals developed by genetic engineering.

(DMB 23)

(DMB 24)
M.Sc. (Final) DEGREE EXAMINATION, JUNE 2010. Second Year Microbiology Paper VIII FOOD AND INDUSTRIAL MICROBIOLOGY Time : Three hours Maximum : 100 marks

PART A (5 8 = 40 marks) Answer any FIVE of the following. 1. 2. 3. 4. 5. 6. 7. 8. Canned foods. Irradiation of foods. Beer. Edible mushrooms. Fermentor body construction. Mutations and strain improvement. SSF. Amylases uses.

PART B (4 15 = 60 marks) Answer ALL questions. 9. (a) What are the microbes associated with foods and the sources of contamination? Or Describe the food preservation using the high and low temperatures. Elaborate on the pasteurization of milk and quality testing. Or Explain the food borne infections and their control. Write an essay on fermentation media. Or Discuss the role of microbial strain improvement in improving the fermentation process. How the fermentation end products are recovered and purified? Or Give an account of citric acid production and its uses.

(b)

10.

(a)

(b)

11.

(a) (b)

12.

(a)

(b)

(DMB 24)