Shen Y, et al. High magnitude of light retardation by the zona pellucida is associated with conception cycles. Human Reproduction, 2005 Jun;20(6):1596-606. Photography credits Front cover Retardance pseudocolor image of MII human oocyte Back cover Retardance grayscale image of MII human oocyte Before/After image above spec chart courtesy of RMA NJ
before after
No other contrast-enhancement technique delivers the performance of Oosight. With its unprecedented resolution and calibrated setup, Oosight provides the reproducibility and sensitivity Orientation Vector Map required of a grading routine, as well as the speed needed for micromanipulation.
after
normal
abnormal
On the left, human MII oocyte has a normal barrel-shaped spindle (azimuth skew from barrel shape is 5.12) . On the right, this human MII oocyte has an abnormal tri-polar spindle (azimuth skew from barrel shape is 49.4). Inner zona and spindle retardances are not shown, but these data are provided by the Oosight system as well.
Basic
Meta
Because spindle screening can improve efficiency of gamete selection, it should be considered when choosing eggs for freezing or fertilization by ICSI. Dr. N Noyes, NYU IVF Program
About CRi
Cambridge Research & Instrumentation, Inc (CRi) is a global leader in biomedical imaging dedicated to providing comprehensive solutions that enable our customers to perform cutting-edge research and provide better healthcare. CRi technology helps extract physiologically and medically significant information from biological and clinical samples with intact morphological and biochemical context in tissues and organisms. With over 80 patents pending and issued, CRis award-winning innovations are being utilized around the world.
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Notice to purchaser: The Oosight Imaging System is meant to be used for research purposes only.