EMBRYOLOGY AND DEVELOPMENTAL BIOLOGY

Code: 90010 Curricular Year: 1st ECTS Semester: 2nd Compulsory Credits: 5.0

Lecturer(s): Fernando Garcia e Costa (CCP), Jos Ferreira da Silva (R) 1. Contact hours:
Lectures - 26 Praticals - 26 Total - 52

2. Objectives: Learning of morphological and functional / molecular aspects concerning fertilization, cleavage, gastrulation, neurulation and organogenesis. Learning of basic cellular and molecular mechanisms of embryonic / foetal development. Learning of basic notions about the mechanism of generation of some congenital malformations. 3. Programme: Theoretical programme - Fertilization morphological and molecular aspects. Embryogenesis morphological and molecular aspects of cleavage, gastrulation and neurulation; developping fate of the ectoderm, mesoderm and endoderm. Mechanisms of development differentiation (genome inalterability; restriction, determination and differentiation; regulation of cell diversity and differentiation); patterning; cellular migration; cell death; growth. Organogenesis serous membranes; respiratory, digestive, urinary, sexual (male and female), skeletal and muscular systems; face and pharyngeal arches. Practical programme Spermatogenesis and oogenesis. Observation of chicken telolecithal egg and its enveloping structures and observation of chicken embryo and its associated membranes. Sex chromatin. Observation of embryo models. Microscopical aspects of embryonic development and microscopic anatomy of early foetal organs. Anatomical classification of the placentae. Age determination in Mammal and Avian foetuses. Observation of some teratological cases in Domestic Mammals. 4. Bibliography: Sadler TW (2010) Langman: Embriologia Mdica. 11th edition. Editora Guanabara Koogan S.A. Climent S, Sarasa M, Domnguez L, Muniesa P & Terrado J (1998) Manual de Anatoma y Embriologa de los Animales Domsticos. Editorial Acribia S.A. mechanisms of development (Chapter 7) Carlson BM (2009) Human Embryology and Developmental Biology. 4th edition. Mosby-Elsevier fertilization and cleavage (Chapters 2 and 3) 4. Assessment: Practical matters knowledge is evaluated through the elaboration of reports concerning three practical themes along the semester. Its mean value contributes to 30% of the final score and must be equal or superior than 9.5 points (in 20). If this mean is less than 9.5 or if the student cannot be evaluated this way, he must be submitted to an oral practical exam, which note must be equal or superior than 9.5 points and contributes to 40% to the final score. Theoretical matters knowledge is evaluated through a written exam with multiple-choice questions, which contributes to 70% or 60% to the final score, according to the type of practical matters evaluation, and must be equal or superior than 9.5 points (in 20).
The scientific and pedagogic coordinator _______________________________ Data __ / __ / ____