Oncquest Laboratories Limited corporate profile

Everyone talks about QualityWe Practice and Deliver Quality

For Details please contact: Dr. Ravi Gaur Regd.Office: Oncquest Laboratories Limited, 3 - Factory Road, Adj. Safdarjung Hospital, New Delhi - 29 Tel.: 91-11-26101240, Facsimile: 91-11-26182231, E-mail: info@oncquest.net) Website: www.oncquest.net

Oncquest: Journey so far

Oncquest started its journey from 2003 as an advanced diagnostic laboratory with an incisive diagnosis in the field of oncology. In Year 2007,with its new identity i.e. Oncquest Laboratories Ltd turned out into a State of- The-Art Laboratory at New Delhi, fully equipped with molecular technologies like pharmocogenomics, proteomics, companion diagnostics, bioinformatics and biomarker studies providing a comprehensive menu of general pathology & specialty laboratory assays with unparalleled services

Oncquest: Journey so far

2002: 2003: 2004: 2006: 2008: 2009: 2011: Molecular Diagnostic Research Laboratory Commenced Commercial Operations
Molecular and Flow Cytometry

2011:

Surgical Pathology and IHC NABL accreditation as per ISO 15189: 2003 NABL accreditation as per ISO 15189: 2007 Introduction of PCRs for Infectious segment College of American Pathology (CAP) accreditation NABL accreditation (renewed)

Oncquest: Role & Objectives

Provide effective diagnostic solutions
Commercially available assay adoption and utilization Custom assay development using various molecular and pathological techniques

Develop novel molecular assays to provide:

Effective assessment of diagnosis, prognosis and monitoring Appropriate management of therapy and drug resistance Assessment of risk and predisposition

Identify Biomarkers
Therapeutic targets Clinical targets

Our Purpose
To facilitate Personalized Medicine at Point-ofCare
Integrate patients genomic profile with clinical data Support physician decisions Guide physicians to appropriate molecular & other diagnostics Support interpretation of results Notify physician when new information becomes available indicating change in treatment strategy

To reintegrate clinical data and drive novel drug development, and novel therapeutic practices

Our Mission
Making the Best Better "Extend the survival & improve the quality of life of cancer patients by evolving high end technologically advanced; cost effective; branded molecular testing algorithms; to assist doctors & patients to optimize cancer care and diagnose cancers at early stages of malignancy". Oncquest strives to extend the survival & improve the quality of life of patients by : discovering technologically advanced ; cost effective; branded, testing algorithms diagnosing with accuracy and reliability defending against wide array of disease

About Us
Having customer base of over 500 contracted hospitals. A geographic spread of pan-India with a network of patient services centres in major metros & sample collection centres in 85 major cities across India. Managing Multiple Hospital Labs & providing High End Assays to all major hospitals. Pioneer to launch Real-Time PCR in 2003. Achieved belief & conviction of 12000 renowned clinicians. Maintained Excellency in Quality & services in 2 million patients by providing wide range of investigations in different disease area. Clinical Trial services Research and development Services ( R & D ) Started complete diagnosis in 2009. Started Pharmacogenomics/Proteomics health care services in 2009.

About Us (contd)
Pioneer in introducing Clinical Face of Cancer Diagnostics in India:
Core competency lies within Cancer Diagnosis With a philosophy of enhancing our core competence in molecular diagnostics and maintaining international quality, Oncquest has set new benchmarks for others to follow, in just a span of 8 years. A key element of Oncquest 's services has been in establishing several new technologies and making these commercially available for the first time in India Oncquest has introduced many high - end technovations in Cancer diagnostics such as Flowcytometry Real-Time PCRs & Nested RT- PCRs Chromosomal Analysis & FISH (Fluorescent in-situ Hybridization), Histopathology & Immunohistochemistry Bi Directional Gene Sequencing

Team at helm of affairs

Mr. Aditya C. Burman

Director

Dr. Ravi Gaur

MD (Pathology ) : Vice President (Operations)

Team at helm of affairs

Molecular Pathology / FISH
Dr. Sarjana Dutt Dr. Monika Shashank Dr Dinesh Gupta Team Of Qualified Scientist and Technicians Surgical Pathology/IHC Dr. Ritesh Sachdev Dr. Sudhir Jain Dr. C.K. Kunwar Dr. Naveen Agarwal & Team

Flow Cytometry Dr. Ritesh Sachdev Dr. Naveen Agarwal & Team

Our Purpose
To facilitate Personalized Medicine at Point-ofCare
Integrate patients genomic profile with clinical data Support physician decisions Guide physicians to appropriate molecular & other diagnostics Support interpretation of results Notify physician when new information becomes available indicating change in treatment strategy

To reintegrate clinical data and drive novel drug development, and novel therapeutic practices

Organization
Marketing / Business Development Customer Care / Phlebotomy

Reference/ Central Laboratory

Satellite Laboratories

Clinical Trials Project Management

Logistics/ Purchase/ HR/ Finance

Industrial Training
Quality Assurance / Safety Management

Capabilities
Technical Centers of Excellence
Molecular Pathology Surgical Pathology Incl Immunohistochemistry (IHC) Hematology and Flow Cytometry Surgical Pathology

Cytogenetic & FISH Immunology

Biochemistry Research & Development:
PCR

Gene Sequencing
Assay development Biomarker studies

Super Specialized Range

Molecular oncology
BCR-ABL Translocation PML RaRA Translocation JAK-2 Mutation Analysis FIP1L1 PDGFR Mutation

Flowcytometry
Panels for diagnosis & prognosis of Leukemia and Lymphoma.

Gene Sequencing
Imatinib Resistance mutation analysis K-Ras Mutation analysis EGFR Mutation analysis C-Kit Mutation analysis

Immunohistochemistry
Final Diagnosis Panel

Flourescence In Situ Hybridization

Her2neu by FISH MDS Panel by FISH Multiple Myeloma by FISH

Clinical Trial Services

We are committed to serve the analytical part of clinical trials (Phase I IV)carried out by various pharmaceutical companies & CROs. A well qualified and trained project management team with extensive clinical trial laboratory experience to ensure quality results. Assists pharmaceutical and biotech companies with protocol design and also provide regulatory expertise and project management service tools to advance the process efficiencies. Salient Features of our Clinical Trials Services :
Centralized Reference Laboratory A Comprehensive Assay Menu of Over 1000 Assays Customized Protocol Assay Requisition Form Customized Trial Specific Specimen Kits Bar Coded Specimen Tracking Protocol Specific Investigator Instruction Manual Data Management Investigator Training Investigator Site Support Extensive Logistics Support Site Supplies Sample Storage

Clinical Trial Work Flow

Oncquest Laboratories (Central Laboratory)
Project Consultation Sample Logistics Sample Processing Customized Reporting Data Analysis and Archiving

Site
Site Training Logistic support for: delivery of consumables, collection and shipment, as per protocol Report delivery

Sponsor/CRO
Project Consultation Visualization as per protocol Customized Kits, TRFs, Labels & Lab Manual Customized reporting & IT support

General Work Flow

Research & Development Wing A quest for the best!

Oncquest focuses on :
Developing & making available clinically relevant, highly sensitive, accurate, need-based and cost effective tests. State-of-the-art technology for improved diagnosis ensuring valuable and economical healthcare solutions pertaining to India. Catering to the needs of National and International clients in the execution of customised projects. Creating scientific awareness with respect to basic clinical information as well as latest developments in clinical lab medicine. Becoming a National and International Reference Centre for carrying out clinical research and testing for a few selective diseases.

Quality At Fore Front

Quality Standards: The assurance of our Reliability
At Oncquest our core focus is to provide Quality testing. We strictly adhere to all Standard Operating Procedures under the able guidance of our core technical team. The design of the Quality Management System implemented at Oncquest is based on norms laid down by ISO: 15189: 2007 standards of Medical Laboratory Management Systems and NABL & CAP requirements The system reflects the organizations desire to be best-in-class as well as provide a framework for achieving patient satisfaction. This system incorporates the twin objectives of Customer Satisfaction and Continual Improvement into the organizations operations

Quality Audits & Inspections

Accreditation Audits
National Accreditation Board for Testing and Calibration Laboratories (NABL) College of American Pathologists (CAP)

Internal Audits

Third Party Audits

Clinical Trials Panel Companies [IHO]

Logistic Management
Efficient Logistics: Service to reach you closer
Oncquest logistics operations strictly complies with IATA/ICAO transport regulations. Large team of pick-up courier riders cum phlebotomists, extensive network of patient service centres, collection centres, nationwide tieups with reputed courier companies stretches our hands for a wider reach across the country. Oncquests logistics system ensures that the integrity of samples is maintained right from the time it is picked up till it is delivered to the processing workstation. A convenient home sample collection service brings world-class diagnostics to the patient's doorstep. Just a phone call and our welltrained phlebotomist will be at your doorstep for sample collection.

Test Menu

Oncquest offers over 1000 assays spanning the screening, diagnostic, monitoring & prognostic spectra of Laboratory assays. Constant upgradation of menu by new tests in pipeline Constantly upgradation of facilities by new technologically advanced instruments. With a test menu covering a wide range including:
Molecular Biology Histopathology incl Immunohistochemistry (IHC ) Haematology Flowcytometry Cytogenetic Immunology Biochemistry Clinical Pathology Microbiology ELISA

Oncquest is the first choice of over 10,000 doctors today

We Meet Them All

Parameter
Quality Management System Quality control programme

CAP

NABL

External Quality Assurance External Quality Audit(Second party audit by clinical research org) Internal Audit(Planned, Surprise,IQAS) Standard Operating Procedures Documentation Systems

Training

Storage and Archival

Oncquest has dedicated refrigerators and deep freezers for short and long time specimen storage Temperature controlled corrugated boxes used for transportation of samples.

Logistic network with cold chain facilities linked to the centralized laboratory to ensure minimal turnaround time.
Dedicated archival room for storage of records

Partnering with Oncquest

Partnering with Oncquest to manage the In House Hospital Laboratory
Quality Assurance and Quality Control NABL Consulting and Accreditation Pan-India Logistics Network Novel assay sourcing and deployment Localized marketing services Staff Training

Being a part of our Client Network for Clinical Trials and all Diagnostic Support Services across India
Oncquests partner network can be leveraged for conducting Clinical Trials and Clinical Studies The expertise residing with all of our centers can be leveraged to better address specialized diagnostic needs

Partnering with Oncquest

(Contd)

Oncquest offers consultation to its partners for:

Laboratory Design and Layout Equipment: Purchasing and Deployment Consumables: Purchasing, and Optimization Staffing and Training Quality Systems
Documentation and SOP Development Safety and Emergency Environmental cultures and documentation for NABH submission

Audit Coordination and Follow-Up

Partnering with Oncquest

(Contd)

Oncquest routinely gives CMEs with certificate of participation to its clients & prescribers
Seminars about new developments in Diagnostics
New test usage New technologies Compiled usage data

Clinical Trial Site Training and Instructions

Required by all CROs and Pharmaceutical Companies

Oncquest is happy to coordinate such sessions with weekly/monthly doctors meetings at our partner hospital

Instrumentation
FACS CALIBUR FACS CANTO ROCHE CTM 48 ABI BIO-RAD Olympus Metaphase finder Lab India Leica Automatic tissue processor Microtome

Flow Cytometery

Molecular Biology

Cytogenetics

Surgical Pathology

Sysmex KX-21 Beckman Coulter

Hitachi 902 Abbott Architect TECAN ELISA

Roche AVL Roche B G analyzer Tulip coagulometer Miscellaneous

Routine Assays

Hematology

Biochemistry/ Hormonal assays/ Immuno-assays

Continuous Improvement

Patient Feedback

Client Feedback Internal and External Suggestions

Future Activities
Tumor-Banking Services
Through Oncquest to Bio-Bank Partners On Site or Central Repositories
Cryo-Banking Fresh Tissue DNA & RNA Storage Slide and Block Storage

Environmental Microbiology Services

With the ongoing MSRA and other Antimicrobial Resistant Pathogen issues in India and globally, Oncquest aims to provide certified monitoring services for its Partner Hospitals

Oncology Patient Coordination and Logistics Services

Our Locations

Partnerships
It is rare to find a business partner who is selfless. If you are lucky it happens once in a lifetime. Michael Eisner In this new wave of technology, you can't do it all yourself, you have to form alliances. Carlos Slim Helu

Team Oncquest Acknowledges Your Valuable Time and Attention

Thank You
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