INTRODUCTION
History
1. Contributing Scientists
A.) Robert Hooke (1665) looked at cork under a microscope, identified and
named cells.
B.) Anton Von Leeuwenhoek (1666) Dutch. Was the first person to identify
microorganisms.
C.) Mattias Schleiden (1838) German. Found that all plants are composed of
cells.
D.) Theodor Schwann (1839) German. Found that all animals are made of
cells.
E.) Rudolph Virchow* (1858) German. Concluded that all cells come from
pre-existing cells.
* Disputed the theory of spontaneous generation
2. Cell Theory
A.) All living things are made of cells.
B.) All cells come from other cells.
* Omnis cellula e cellula – Latin. From cells come cells.
3. Terminology
A.) cyte or cyto = cell
* cytology – the study of cells
* erythrocyte – a red blood cell
ADDITIONAL INFORMATION:
4.1: Microscopes
ADDITIONAL INFORMATION:
READ
3. Prokaryotic Cells
A.) key features:
1. Do NOT have:
a.) nucleus
b.) organelles
2. DO have:
a.) pili – help attach it to surfaces
b.) capsule – surrounds the cell wall and further protects the cell surface.
Also helps the cell stick to things. (is sugar-based)
c.) nucleoid region (DNA) – no membrane surrounds it.
d.) cell wall (protein bond) – protects the cell and helps maintain its shape.
e.) prokaryotic flagella (flagellum) – helps it move.
ADDITIONAL INFORMATION:
1. Defining features
A.) Nucleus
B.) Compartmentalized – divided into different compartments
C.) Contain organelles (complexity)
*Organelles
1. sub-cellular structures
2. membrane bound
3. have unique internal environments
2. List of Organelles:
A.) ALL eukaryotic cells have (organelles):
1. Nucleus
a.) nuclear envelope
b.) nuclear pores
c.) nucleoplasm
d.) nucleolus
e.) chromatin (DNA)
2. Rough Endoplasmic Reticulum (Rough ER)
3. Smooth Endoplasmic Reticulum (Smooth ER)
4. Golgi apparatus (bodies)
5. Transport vesicles
6. Mitochondrion
B.) Plant Cells ONLY (organelles)
1. Chloroplast
2. Central Vacuole
C.) Animal ONLY
1. Lysosome
D.) Protist ONLY
1. Contractile vacuole
ADDITIONAL INFORMATION:
1. Nucleus
A.) Function
1. Controls all cellular activity – brain
2. Storage of DNA
a.) chromosomal DNA (chromatin/ heredity)
- 46 chromosomes (38,000 genes)
B.) Structure
1. Surrounded by membrane (nuclear envelope)
- Nuclear pores allow passage
2. Contains nucleoplasm (water + solutes)
2. Nucleolus
A.) Function:
1. ribosome synthesis
B.) Structure:
1. Made of proteins
2. Housed in nucleus
3. Ribosomes
A.) Function
1. protein synthesis
B.) Structure
1. Made of protein and RNA
C.) Types:
1. Free Ribosomes
a.) local protein synthesis
2. Bound Ribosomes
a.) secreted proteins
ADDITIONAL INFORMATION:
Rough ER often adds sugar to a polypeptide, making a glycoprotein.
Transports glycoprotein to the Golgi Apparatus
6. Golgi Apparatus
A.) Function
1. processing, modification, sorting, shipping of molecules
produced by the ER
2. Synthesis of some molecules (sugars): hyaluronic acid
B.) Structure
1. Consists of several stacks of cisterna
2. Cis face – receiving in transport
3. trans face – shipping vesicles
ADDITIONAL INFORMATION:
The modified proteins become part of the plasma membrane itself or part of another
organelle
7. Lysosome
A.) Function
1. Digestion of macromolecules
*Intracellular Digestion
2. Recycling of materials (autophagy*)
*phagy = eating
*tadpoles
*humans
B.) Structure
1. membrane bound sac
2. contains hydrolytic enzymes
3. pH = 5 (the cell cytoplasm is about pH 7)
C.) Examples of Function:
1. phagocytosis – when a cell eats another cell
a.) amoeba
b.) macrophage:
8. Vacuoles
A.) Types of vacuoles
1. Central Vacuole (plants)
2. Contractile Vacuole (protist)
3. food vacuole (animal)
B.) Functions
1. central vacuole
A.) storage
- organic compounds
- ions
- waste materials
- pigments
- poisons (defense)
- water
C.) Structure of central vacuole
1. membrane bound sac
2. surrounding membrane = tonoplast
ADDITIONAL INFORMATION:
9. Peroxisome
A.) Function
1. Various metabolic tasks
2. Example:
H2O – catalose H2O + O2
B.) Structure:
1. membrane bound sac
2. contains metabolic enzymes
10. Mitochondrion
A.) Function:
- site of cellular respiration
*energy producer
C6H12O6 + O2 CO2 + H2O + energy
B.) Structure
1. Surrounded by double membrane
2. 1-10µm long
3. contains DNA (mDNA)
intermembrane
space
outermembrane
intermembrane
12. Chloroplast
A.) Function:
- photosynthesis (CO2 + H2O -- sunlight C6H12O6 + O2)
B.) Structure:
thylakoid
disc grana
intermembrane
intermembrane space
outermembrane stroma
(fluid)
13. Cytoskeleton
A.) Function:
1. shape and support of cell
2. movement
a.) cell
b.) organelles
B.) Structure:
1. Microtubules – made of tubulin – originate from (grow out of)
centriole. Main structural components of cilia and flagella. (anchor
organelles, act like tracks for organelle movement and also guide
the movement of chromosomes when cells divide.)
2. Microfilaments – solid rods composed of mainly globular
proteins called actin, arranged in a double chain. (support
structure)
3. Intermediate filaments – made of fiberous proteins and have a
ropelike structure. (reinforce cell shape, anchor certain
organelles like the nucleus)
14. Cilia
A.) Function
-swimming or sweeping
15. Flagella
A.) Function:
-swimming
17. Centrioles
A.) Function
-cell reproduction