Lymphoid Organs

Lab 2

Primary or Secondary
Primary Lymphoid Organs major sites of lymphocyte development produce a large repertoire of reactive cells and to eliminate selfreacting cells. Thymus and Bone Marrow

 Secondary Lymphoid Organs provide the environment for the proliferation and maturation of cells involved in the adaptive immune response for filtering and trapping antigens provide the environment for cell-cell interaction and cytokine-cell interaction. Spleen, Lymph nodes, MALT, GALT, BALT

Features of the Bone Marrow

production of blood cells in bone marrow begins roughly 4-5 months after conception. Stem cells immigrate from the liver into the bone marrow, where the "microenvironment" is decisive for the development of stem cells. This stroma consists of endothelial cells, fat cells, osteoblasts and fibrocytes. mature the B lymphocytes. stimulates the proliferation and differentiation of the precursor cells.

Characteristics of Thymus
T cells also referred as T lymphocytes largest and is in active stage mostly during pre adolescent stage and neonatal (childhood) stage. Thymus commences atrophy process of either incomplete or complete expenditure of body parts in case of early teenage. In such cases, thymic stromal cells are being replaced by fat (adipose) tissues.

 15 grams during the birth of child, about 35 grams during puberty stage, exactly 25 grams in adult life, as low as 15 grams in the age of 60 and less than 5 grams in the age of 70.

Spleen
commonly fist-shaped, purple, and about 4 inches long acts as a filter for blood as part of the immune system. Old red blood cells are recycled in the spleen, and platelets and white blood cells are stored there. The spleen also helps fight certain kinds of bacteria

 The mucosa-associated lymphoid tissue (MALT) (also called mucosa-associated lymphatic tissue) is the diffusion system of small concentrations of lymphoid tissue found in various sites of the body, such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin. GALT (gut-associated lymphoid tissue. Peyer's patches are a component of GALT found in the lining of the small intestines.) BALT (bronchus-associated lymphoid tissue)

 It is exemplified by the lymph nodes, and the lymphoid follicles in tonsils, Peyer's patches, spleen, adenoids, skin, etc. that are associated with the mucosa-associated lymphoid tissue (MALT).