2. Endometrial repair
4. cyclcity:
– Reorganization of uterine
endometruim
• High degree of
Lactation
The Mammary Gland
- Protection: immunoglobulins
The Mammary Gland
Embryo Origin:
–
The Mammary Gland
Secretory Tissues:
– Alveoli:
Alveolus:
– basic secretory unit; lined by epithelial cells
which synthesize and/or secrete:
• protein -
• lactose –
Blood Flow
(cattle)
Example:
What volume of blood would a 1400 lb. Holstein
pump per day?
• Estrogens:
– follicle, placenta,
• Progesterone:
– corpus luteum, placenta,
• Corticoids:
– adrenal cortex
Steroid Hormones and Mammogenesis
1)
2)
2)
Mammogenesis
(Mammary Growth and Development)
• Placental E2 + luteal P4 =
– duct development
– lobulo-alveolar development
– suppression of milk synthesis
(P4 suppresses
α-lactalbumin; lactose synthesis
Mammogenesis
(Mammary Growth and Development)
• increases glycogenolysis
• Lactogenesis = initiation of
milk synthesis
– initiated in the E2/P4
“primed” mammary
gland when:
• corpus luteum regresses
• P4 declines
• cortisol increases
• PRL, GH increase
– these circumstances occur
at parturition