BIOSTATISTICS
First Semester 1428/1429
Section# 15252 & 15254
Biostatistics:
If the information is obtained from biological and medical
sciences,thenweusethetermbiostatistics.
Populations:
Apopulationisthelargestgroupofpeopleorthingsinwhichwe
are interested at a particular time and about which we want to make
somestatementsorconclusions.
Samples:
From the population, we select various elements (or individuals)
on which we collect our information. This part of the population on
whichwecollectdataiscalledthesample.
Sample Size:
The number of elements in the sample is called the sample size
andisdenotedbyn.
Variables:
The characteristics to be measured on the elements of the
populationorsamplearecalledvariables.
Variables:
Thecharacteristicstobemeasuredontheelementsofthe
populationorsamplearecalledvariables.
Example of variables:
-Height
-no.ofcars
-sex
-educationallevel
Types of Variables:
(1)QuantitativeVariables:
Thevaluesofaquantitativevariablearenumbersindicatinghow
muchorhowmanyofsomething.
Examples:
-height
-familysize
-age
(2)
Qualitative Variables:
Thevalueofaqualitativevariablearewordsorattributes
indicatingtowhichcategory
anelementofthepopulationbelong.
Examples:
-bloodtype
-educationallevel
-nationality
Examples:
1. Family size (x = 0, 1, 2, 3, )
2. Number of patients (x = 0, 1, 2, 3, )
Continuous Variables:
Acontinuousvariablecanhaveanyvaluewithinacertain
intervalofvalues.
Variable
Quantitative
Discrete
Continuous
Qualitative
Used for:
- continuous quantitative variables
- discrete quantitative variables with large number of
different values
Example: (Simple frequency distribution or ungrouped
frequency distribution).
The following data represent the number of children of 16
Saudi women:
3, 5, 2, 4, 0, 1, 3, 5, 2, 3, 2, 3, 3, 2, 4, 1
Simplefrequencydistributionoftheno.ofchildren
no.ofchildren
(variable)
0
Frequency
(no.ofwomen)
1
0.125
12.5%
0.25
25%
0.3125
31.25%
0.125
12.5%
0.125
12.5%
1.00
100%
Total
n=16
RelativeFreq.(R.F.)
(=Freq/n)
0.0625
PercentageFreq.
(=R.F.*100%)
6.25%
Note
Totalofthefrequencies=n =esamplesizeTh
Relativefrequency=frequency/n
Percentagefrequency=Relativefrequency*100%
Example 1.2:
(grouped frequency distribution)
Thefollowingtablegivesthehemoglobinlevel(g/dl)ofasampleof50
men.
17.017.715.915.216.217.115.717.313.516.3
14.415.815.316.413.716.216.416.117.015.9
14.016.216.414.917.816.115.518.315.816.7
15.915.313.916.815.916.317.415.017.516.1
14.216.115.715.117.416.514.416.317.315.8
Frequency
(no.ofmen)
Relative
Frequency
Cumulative
Frequency
Cumulative
Relative
Frequency
13.0-13.9
14.0-14.9
15.0-15.9
16.0-16.9
17.0-17.9
18.0-18.9
3
5
15
16
10
1
0.06
0.10
0.30
0.32
0.20
0.02
3
8
23
39
49
50=n
0.06
0.16
0.46
0.78
0.98
1.00
Total
n=50
1.00
Notes
class interval = C. I.
Cumulative frequency of a class interval = no. of values (frequency)
obtainedinthatclassintervalorbefore.
upper limit + lower limit
Mid-Point(ClassMark)ofC.I=
2
ClassInterval
TrueC.I.
Classmid-point
frequency
13.0-13.9
14.0 - 14.9
15.0-15.9
16.0-16.9
17.0-17.9
18.0-18.9
12.95-13.95
13.95 - 14.95
14.95-15.95
15.95-16.95
16.95-17.95
17.95-18.95
3
5
15
16
10
1
lowerupper
limitslimits
(L.L)(U.L.)
TrueTrue
lowerupper
limitslimits
(13.0+13.9)/2=13.45
(14.9+14.9)/2=14.45
15.45
16.45
17.45
18.45
0.35
0.30
0.25
0.20
0.15
0.10
0.05
0.00
15
10
5
0
13.45
14.45
15.45
16.45
17.45
13.45
18.45
Hemoglobin level
15.45
16.45
17.45
18.45
Hemoglobin level
20
20
15
15
10
14.45
10
0
12.45 13.45 14.45 15.45 16.45 17.45 18.45 19.45
Hemoglobin level
0
12.45 13.45 14.45 15.45 16.45 17.45 18.45 19.45
Hemoglobin level
18
16
14
12
10
8
6
4
2
0
12.45
13.45
14.45
15.45
16.45
17.45
18.45
19.45
60
50
40
30
20
10
0
Mid 13.45 14.45 15.45 16.45 17.45 18.45
Point
Forrepresentingcumulativefrequencyorcumulativerelativefrequency
distributions:
CumulativeCurves
CumulativePolygon(ogives)