Esterified Fatty Acid Complex

NOTE Esterified oils are NOT the same as Essential oils

NOTE:
and therefore are not a source of omega 3 oils

By Dr. Kim Vanderlinden

April 22, 2009
ANTI-INFLAMMATORY
Double blind clinical studies have demonstrated
potent anti-inflammatory effects, both as a
topical cream and as an oral supplement.
 EFAC Properties
ABSORBED TOPICALLY
Therefore it is useful in a topical cream form.

With topical analgesics absorption or lack thereof is:

“THE CRITICAL ISSUE”
Skin permeability is highly selective. Is it logical to use
herbs or anti-inflammatory agents that are not absorbed?

Even if a substance has anti-inflammatory properties,

it is irrelevant if it doesn’t reach target tissues.
 INFLAMED TISSUE = PAINFUL TISSUE

Inflammation is acore pathology that impacts many

disorders besides arthritis: heart disease, cancer and asthma etc
Even the process of aging is largely effected by inflammation.

Helping your patients to limit inflammation can

have several positive impacts on their health.
Mechanism of Action:
EFAC promotes healthy cell membranes
It is believed that EFAC works similar to essential oils.
However clinically the trial results have demonstrated far
greater anti-inflammatory action than fish or omega 3 oils.

Unlike anti-inflammatories such as NSAIDs where inhibition of

cell growth is a concern, with EFAC research has shown new
tissue grow. In a gingivitis model, researchers found that new
tissue growth occurred with direct EFAC application.
Anecdotal reports from patients have often been
dramatic, and based on current treatment options,
at times seem almost too good to be true.

Patients have been using the EFAC cream for many

disorders ranging from the various types of arthritis to
migraines to shingles to fibromyalgia to restless leg etc.

However the research to date has primarily been on knee

osteoarthritis, as knees are often used as the benchmark
for studying arthritic and joint health.
Journal of Rheumatology 2004
WITHOUT MENTHOL
Journal of Strength and Conditioning 2005
WITHOUT MENTHOL
Journal of Strength and Conditioning 2005
WITH MENTHOL

GET INVOLVED IN RESEARCH!

 Journal of Rheumatology (without Menthol) 2004

KNEE OSTEOARTHRITIS
PATIENTS WERE TESTED:
Before applying the cream
30 minutes after the first application
30 days after applying the cream twice daily
WHAT WAS TESTED:
Range of Motion
Ability to ascend and descend stairs
Ease of getting up from a sitting position
Balance of patients stepping down
 RESEARCH RESULTS:
After 30 Minutes
Patients improved after a single application of the cream

After 30 Days
Patients improved after 30 days (applied cream twice daily),
demonstrating LONG-TERM benefit
Clinically Proven to Provide Relief in Minutes!

EFAC is absorbed topically

Menthol is added to EFAC to provide maximum benefit

-Counter irritant and cooling sensation of menthol
-Deep penetrating benefit of anti-inflammatory EFAC
to reach target tissues
-Enhance pre and post treatment results

EFAC is the topical of choice!

In my experience the majority of patients,
approx 80%, experience benefit within 10 minutes.
Therefore this is a great tool that enables you to help
most patients, including those in acute distress.

Relief usually lasts a couple of hours, but sometimes longer.

With regular use there is lasting benefit.

Less Pain
Less Stiffness
Less Cramping
 JOURNAL of RHEUMATOLOGY 2002

SCRIPP’S CONFERENCE SAN DIEGO, 2007

AWARDED BEST PAPER
Out of the 90 Papers Presented

GET INVOLVED IN RESEARCH!

 SCRIPP’S CONFERENCE 2007
AWARDED BEST PAPER
Patients with OA of the knees were tested to see if their pain
decreased and how far they could walk in a timed 6 minute walk
when they were supplemented with EFAC.

The walking portion of this double blind clinical trial is considered

very important due to the objective nature of the measurement.

Presumably patients with knee arthritis would walk slower due to

pain and/or stiffness.

Patients were tested prior to EFAC supplementation to establish a

baseline and then after 2, 4 and 8 weeks.
PAIN-
PAIN Patients reported less pain after 2 weeks and
their pain levels continued to decrease over the 8 weeks

NOTE: The placebo group of patients DID NOT

improve, making these results even more significant
 My Experience
I have used the caps on a wide range of inflammatory
disorders, often with excellent success. Patients usually
report benefit earlier, however I like to give it 6 or 7 weeks
to see if EFAC is going to help and if so continue at 3 caps

Dosage- I typically double the dose in the first month to 3

caps twice daily. Patients get better faster and of course
are pleased, and as a result are very committed.

EFAC is a great complement to other physical therapies.

I have taken EFAC for 4 years because I believe one of the

best ways to promote health is to limit inflammation.
EFAC and IP6 are by far the top selling supplements in my
practice. However I wrote a book on IP6 and so my IP6 sales are
higher than would be expected.

The use of EFAC is so high because pain is so prevalent and

inflammation impacts so many disorders. And for healthy adult
patients, limiting inflammation is a strategy I often employ in an
attempt to prevent future problems.

You will earn approx $200 when a patient uses EFAC for a year.
Depending on your patient load you can do the math.
More importantly because EFAC is so effective it can generate
new patient referrals because:

when something works people talk.

talk
 EFAC
Versus
Glucosamine
 Glucosamine Arthritis Intervention Trial

NIH National Institute of Health

The GAIT trial conducted by the NIH is the largest

(1583 patients) and most rigorous clinical trial ever
conducted on the effects of glucosamine and/or
chondroitin for joint health.
KNEE Osteoarthritis-10 groups
5 early OA 5 more advanced OA
1-Glucosamine only 2-Glucosamine Only
3-Chondroitin only 4-Chondroitin only
5-Glucosamine & Chondroitin 6-Glucosamine & Chondroitin
7-Placebo 8-Placebo
9-Celebrex 10-Celebrex

2 Part Trial: 2006 Pain 6 m treatment

2008 Cartilage 24 m treatment
5 of the 6 glucosamine and/or chondroitin treatment groups
numbers 1, 2, 3, 4, and 5 were not significantly different than
placebo at relieving pain by at least 20% after 6 months.

Only one glucosamine and chondroitin group (no 6) was better

than placebo. However the authors cautioned not to draw
conclusions due to the small size (72 patients out of the 1583).
Glucosamine sellers often only refer to this group and forget the
majority or the other 5 groups and the researcher’s conclusions!

Patients were given the option to continue for another 18 months

(2 years total) to see the effects on the cartilage. Ironically the
combined glucosamine chondroitin group had slightly more
cartilage loss than placebo.
 (or lack thereof )

Overall glucosamine and/or chondroitin

WAS NOT significantly different than placebo
at reducing knee pain after 6 months or
preventing the loss of cartilage after 2 years.
EFAC vs glucosamine
EFAC is Clinically PROVEN
EFAC is far more effective
EFAC provides Rapid Relief
Cream in Minutes
Capsules in 2 Weeks
Hence the EFAC brand name:

Superior to Glucosamine
 EFAC Cream EFAC
Capsules
TRUST THE SCIENCE!