The main efferent limb of all cardiovascular reflexes. Can change resistances and volumes of vessels Can change rate and force of contraction of heart Can alter renal excretion of salt and water
Circulation
Bulk transport Diffusion, limited by distance, gradient and molecular mass Circulation ensures exchange vessels in all tissues provided with nutrients All cells linked via the capillary exchange vessels
Ductus arteriosus
Lung s
Foramen Ovale
Liver
Ductus venosus
Splanchnic circulation
Kidneys
Placenta
Physiological Overview
Bulk flow system with variable demand Components are pump, fluid and vessels, potentially each of these can change properties to meet the bodies needs Flow created by energy differences Heart creates flow by creating energy differences, vessel properties modify the flow and this is reflected in the pressure gradients.
LV
Llandis diagram
The heart
Auscultation
First and second sounds First (mitral and tricuspid)
Normal Split
Split both
Auscultation
3rd and 4th heart sounds 3rd (often normal in young, pathological in older ones rushing in) 4th (ventricular malfunction in older people a stiff wall)
Auscultation
Murmurs
Characterised by timing, duration and localisation
ECG
ECG
Heart rate Duration of cardiac cycle Duration of ventricular systole Duration of ventricular diastole
E.H.Starling
The heart-lung preparation. Effectively an isolated heart preparation.
The flow of blood into the heart (pre-load) and the resistance against which the heart has to pump (after-load) can be varied independently
Ventricular volume, and therefore SV, and CO, and arterial and venous pressures can be measured.
The heart is isolated from the central nervous system so that there is no reflex control, heart rate therefore does not change significantly The chest is open so that intrathoracic pressure is constant at atmospheric pressure and does not vary with respiration
S
Increasing volume of heart
Observation s1
Observations 2